2WRS
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![BU of 2wrs by Molmil](/molmil-images/mine/2wrs) | Crystal Structure of the Mono-Zinc Metallo-beta-lactamase VIM-4 from Pseudomonas aeruginosa | 分子名称: | BETA-LACTAMASE VIM-4, CITRATE ANION, CITRIC ACID, ... | 著者 | Lassaux, P, Hamel, M, Gulea, M, Delbruck, H, Traore, D.A.K, Mercuri, P.S, Horsfall, L, Dehareng, D, Gaumont, A.-C, Frere, J.-M, Ferrer, J.-L, Hoffmann, K, Galleni, M, Bebrone, C. | 登録日 | 2009-09-02 | 公開日 | 2010-06-23 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | 主引用文献 | Mercaptophosphonate Compounds as Broad-Spectrum Inhibitors of the Metallo-Beta-Lactamases. J.Med.Chem., 53, 2010
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8E23
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![BU of 8e23 by Molmil](/molmil-images/mine/8e23) | Human DNA polymerase theta in complex with allosteric inhibitor | 分子名称: | 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*GP*TP*CP*CP*AP*AP*TP*GP*AP*CP*AP*GP*CP*CP*GP*C)-3'), DNA (5'-D(*GP*C*GP*GP*CP*TP*GP*TP*CP*AP*TP*TP*G)-3'), ... | 著者 | Mader, P, Pau, V.P.T, Sicheri, F. | 登録日 | 2022-08-13 | 公開日 | 2022-09-28 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | 主引用文献 | Identification of RP-6685 , an Orally Bioavailable Compound that Inhibits the DNA Polymerase Activity of Pol theta. J.Med.Chem., 65, 2022
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8E24
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![BU of 8e24 by Molmil](/molmil-images/mine/8e24) | Human DNA polymerase theta in complex with allosteric inhibitor | 分子名称: | 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, 2-[2,4-bis(trifluoromethyl)phenyl]-N-phenyl-N-[3-(pyridazin-3-yl)prop-2-yn-1-yl]acetamide, DNA, ... | 著者 | Mader, P, Pau, V.P.T, Sicheri, F. | 登録日 | 2022-08-13 | 公開日 | 2022-09-28 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | 主引用文献 | Identification of RP-6685 , an Orally Bioavailable Compound that Inhibits the DNA Polymerase Activity of Pol theta. J.Med.Chem., 65, 2022
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3IOG
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![BU of 3iog by Molmil](/molmil-images/mine/3iog) | Crystal structure of CphA N220G mutant with inhibitor 18 | 分子名称: | Beta-lactamase, GLYCEROL, SULFATE ION, ... | 著者 | Delbruck, H, Bebrone, C, Hoffmann, K.M.V. | 登録日 | 2009-08-14 | 公開日 | 2010-06-23 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.41 Å) | 主引用文献 | Mercaptophosphonate Compounds as Broad-Spectrum Inhibitors of the Metallo-beta-lactamases J.Med.Chem., 53, 2010
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3IOF
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![BU of 3iof by Molmil](/molmil-images/mine/3iof) | Crystal structure of CphA N220G mutant with inhibitor 10a | 分子名称: | Beta-lactamase, GLYCEROL, SULFATE ION, ... | 著者 | Delbruck, H, Bebrone, C, Hoffmann, K.M.V. | 登録日 | 2009-08-14 | 公開日 | 2010-06-23 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.44 Å) | 主引用文献 | Mercaptophosphonate Compounds as Broad-Spectrum Inhibitors of the Metallo-beta-lactamases J.Med.Chem., 53, 2010
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