8SUT
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![BU of 8sut by Molmil](/molmil-images/mine/8sut) | Crystal structure of YisK from Bacillus subtilis in complex with reaction product 4-Hydroxy-2-oxoglutaric acid | 分子名称: | (2~{R})-2-oxidanyl-4-oxidanylidene-pentanedioic acid, Fumarylacetoacetate hydrolase family protein, MANGANESE (II) ION | 著者 | Krieger, I.V, Chemelewski, V, Guo, T, Sperber, A, Herman, J, Sacchettini, J.C. | 登録日 | 2023-05-13 | 公開日 | 2023-11-01 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Bacillus subtilis YisK possesses oxaloacetate decarboxylase activity and exhibits Mbl-dependent localization. J.Bacteriol., 206, 2024
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8SUU
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![BU of 8suu by Molmil](/molmil-images/mine/8suu) | Crystal structure of YisK from Bacillus subtilis in apo form | 分子名称: | Fumarylacetoacetate hydrolase family protein, MANGANESE (II) ION | 著者 | Krieger, I.V, Chemelewski, V, Guo, T, Sperber, A, Herman, J, Sacchettini, J.C. | 登録日 | 2023-05-13 | 公開日 | 2023-11-01 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | Bacillus subtilis YisK possesses oxaloacetate decarboxylase activity and exhibits Mbl-dependent localization. J.Bacteriol., 206, 2024
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8SKY
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![BU of 8sky by Molmil](/molmil-images/mine/8sky) | Crystal structure of YisK from Bacillus subtilis in complex with oxalate | 分子名称: | Fumarylacetoacetate hydrolase family protein, MANGANESE (II) ION, OXALATE ION | 著者 | Krieger, I.V, Chemelewski, V, Guo, T, Sperber, A, Herman, J, Sacchettini, J.C. | 登録日 | 2023-04-20 | 公開日 | 2023-11-01 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Bacillus subtilis YisK possesses oxaloacetate decarboxylase activity and exhibits Mbl-dependent localization. J.Bacteriol., 206, 2024
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7XKC
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![BU of 7xkc by Molmil](/molmil-images/mine/7xkc) | Crystal structure of Daucus Carrot hypoglycemic peptide (DCHP) | 分子名称: | DCHP, SULFATE ION | 著者 | Guo, T, Ren, J.Q, Wang, L, Shi, Y.W, Feng, W. | 登録日 | 2022-04-19 | 公開日 | 2022-05-18 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | 主引用文献 | Characterization of a thermostable, protease-tolerant inhibitor of alpha-glycosidase from carrot: A potential oral additive for treatment of diabetes. Int.J.Biol.Macromol., 209, 2022
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8D4Z
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![BU of 8d4z by Molmil](/molmil-images/mine/8d4z) | Crystal structure of USP7 in complex with allosteric inhibitor FX1-3763 | 分子名称: | 1-({(7M)-7-[1-(azetidin-3-yl)-6-chloro-1,2,3,4-tetrahydroquinolin-8-yl]thieno[3,2-b]pyridin-2-yl}methyl)pyrrolidine-2,5-dione, GLYCEROL, Ubiquitin carboxyl-terminal hydrolase 7 | 著者 | Bell, J.A. | 登録日 | 2022-06-03 | 公開日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | Novel USP7 inhibitors demonstrate potent anti-cancer activity in models of AML, synergy with BCL2 inhibition, and a differentiated mechanism of action To Be Published
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5JXC
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![BU of 5jxc by Molmil](/molmil-images/mine/5jxc) | SynGAP Coiled-coil trimer | 分子名称: | Ras/Rap GTPase-activating protein SynGAP | 著者 | Shang, Y, Zhang, M. | 登録日 | 2016-05-13 | 公開日 | 2016-09-28 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Phase Transition in Postsynaptic Densities Underlies Formation of Synaptic Complexes and Synaptic Plasticity. Cell, 166, 2016
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5IZU
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![BU of 5izu by Molmil](/molmil-images/mine/5izu) | |
5JXB
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3CID
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![BU of 3cid by Molmil](/molmil-images/mine/3cid) | Structure of BACE Bound to SCH726222 | 分子名称: | Beta-secretase 1, D(-)-TARTARIC ACID, N'-[(1S,2S)-2-[(4S)-1-benzyl-5-oxoimidazolidin-4-yl]-1-(3,5-difluorobenzyl)-2-hydroxyethyl]-5-methyl-N,N-dipropylbenzene-1,3-dicarboxamide | 著者 | Strickland, C, Cumming, J. | 登録日 | 2008-03-11 | 公開日 | 2008-06-10 | 最終更新日 | 2017-10-25 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Rational design of novel, potent piperazinone and imidazolidinone BACE1 inhibitors Bioorg.Med.Chem.Lett., 18, 2008
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3CIC
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![BU of 3cic by Molmil](/molmil-images/mine/3cic) | Structure of BACE Bound to SCH709583 | 分子名称: | Beta-secretase 1, D(-)-TARTARIC ACID, N'-[(1S,2S)-2-[(2S)-4-benzyl-3-oxopiperazin-2-yl]-1-(3,5-difluorobenzyl)-2-hydroxyethyl]-5-methyl-N,N-dipropylbenzene-1,3-dicarboxamide | 著者 | Strickland, C, Cumming, J. | 登録日 | 2008-03-11 | 公開日 | 2008-06-10 | 最終更新日 | 2017-10-25 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Rational design of novel, potent piperazinone and imidazolidinone BACE1 inhibitors Bioorg.Med.Chem.Lett., 18, 2008
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3LPI
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![BU of 3lpi by Molmil](/molmil-images/mine/3lpi) | Structure of BACE Bound to SCH745132 | 分子名称: | Beta-secretase 1, L(+)-TARTARIC ACID, N'-{(1S,2S)-1-(3,5-difluorobenzyl)-2-hydroxy-2-[(2R)-4-(phenylsulfonyl)piperazin-2-yl]ethyl}-5-methyl-N,N-dipropylbenzene-1,3-dicarboxamide | 著者 | Strickland, C, Cumming, J. | 登録日 | 2010-02-05 | 公開日 | 2010-04-14 | 最終更新日 | 2017-11-01 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Piperazine sulfonamide BACE1 inhibitors: design, synthesis, and in vivo characterization. Bioorg.Med.Chem.Lett., 20, 2010
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3LPK
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![BU of 3lpk by Molmil](/molmil-images/mine/3lpk) | Structure of BACE Bound to SCH747123 | 分子名称: | Beta-secretase 1, L(+)-TARTARIC ACID, N-[(1S,2S)-1-(3,5-difluorobenzyl)-2-hydroxy-2-{(2R)-4-[(3-methylphenyl)sulfonyl]piperazin-2-yl}ethyl]-3-{[(2R)-2-(methoxymethyl)pyrrolidin-1-yl]carbonyl}-5-methylbenzamide | 著者 | Strickland, C, Cumming, J. | 登録日 | 2010-02-05 | 公開日 | 2010-04-14 | 最終更新日 | 2017-11-01 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Piperazine sulfonamide BACE1 inhibitors: design, synthesis, and in vivo characterization. Bioorg.Med.Chem.Lett., 20, 2010
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3LPJ
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![BU of 3lpj by Molmil](/molmil-images/mine/3lpj) | Structure of BACE Bound to SCH743641 | 分子名称: | Beta-secretase 1, L(+)-TARTARIC ACID, N'-[(1S,2S)-2-[(2R)-4-benzylpiperazin-2-yl]-1-(3,5-difluorobenzyl)-2-hydroxyethyl]-5-methyl-N,N-dipropylbenzene-1,3-dicarboxamide | 著者 | Strickland, C, Cumming, J. | 登録日 | 2010-02-05 | 公開日 | 2010-04-14 | 最終更新日 | 2017-11-01 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Piperazine sulfonamide BACE1 inhibitors: design, synthesis, and in vivo characterization. Bioorg.Med.Chem.Lett., 20, 2010
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3LNK
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![BU of 3lnk by Molmil](/molmil-images/mine/3lnk) | Structure of BACE bound to SCH743813 | 分子名称: | Beta-secretase 1, L(+)-TARTARIC ACID, N'-{(1S,2S)-1-(3,5-difluorobenzyl)-2-hydroxy-2-[(2R)-4-(phenylcarbonyl)piperazin-2-yl]ethyl}-5-methyl-N,N-dipropylbenzene-1,3-dicarboxamide | 著者 | Orth, P, Cumming, J. | 登録日 | 2010-02-02 | 公開日 | 2010-04-14 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Piperazine sulfonamide BACE1 inhibitors: design, synthesis, and in vivo characterization. Bioorg.Med.Chem.Lett., 20, 2010
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4LN0
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![BU of 4ln0 by Molmil](/molmil-images/mine/4ln0) | Crystal structure of the VGLL4-TEAD4 complex | 分子名称: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Transcription cofactor vestigial-like protein 4, ... | 著者 | Wang, H, Shi, Z, Zhou, Z. | 登録日 | 2013-07-11 | 公開日 | 2014-02-26 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.896 Å) | 主引用文献 | A Peptide Mimicking VGLL4 Function Acts as a YAP Antagonist Therapy against Gastric Cancer. Cancer Cell, 25, 2014
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4FRS
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3CIB
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![BU of 3cib by Molmil](/molmil-images/mine/3cib) | Structure of BACE Bound to SCH727596 | 分子名称: | Beta-secretase 1, D(-)-TARTARIC ACID, N'-[(1S,2R)-2-[(2R,4S)-4-benzylpiperidin-2-yl]-1-(3,5-difluorobenzyl)-2-hydroxyethyl]-5-methyl-N,N-dipropylbenzene-1,3-dicarboxamide | 著者 | Strickland, C, Cumming, J. | 登録日 | 2008-03-11 | 公開日 | 2008-06-10 | 最終更新日 | 2017-10-25 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Rational design of novel, potent piperazinone and imidazolidinone BACE1 inhibitors Bioorg.Med.Chem.Lett., 18, 2008
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6IW2
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![BU of 6iw2 by Molmil](/molmil-images/mine/6iw2) | Crystal structure of 5A ScFv in complex with YFV-17D sE in prefusion state | 分子名称: | Envelope protein E, Heavy chain of monoclonal antibody 5A, Light chain of monoclonal antibody 5A | 著者 | Lu, X.S, Xiao, H.X, Li, S.H, Pang, X.F. | 登録日 | 2018-12-04 | 公開日 | 2019-02-13 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Double Lock of a Human Neutralizing and Protective Monoclonal Antibody Targeting the Yellow Fever Virus Envelope. Cell Rep, 26, 2019
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6IW5
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![BU of 6iw5 by Molmil](/molmil-images/mine/6iw5) | |
6IW1
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![BU of 6iw1 by Molmil](/molmil-images/mine/6iw1) | |
6IW4
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![BU of 6iw4 by Molmil](/molmil-images/mine/6iw4) | |
6J9O
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![BU of 6j9o by Molmil](/molmil-images/mine/6j9o) | |
6J67
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![BU of 6j67 by Molmil](/molmil-images/mine/6j67) | |
6IVZ
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![BU of 6ivz by Molmil](/molmil-images/mine/6ivz) | Crystal structure of 5A ScFv complexed with YFV-China sE in postfusion state | 分子名称: | Envelope protein, Heavy chain of monoclonal antibody 5A, Light chain of monoclonal antibody 5A | 著者 | Lu, X.S, Xiao, H.X, Li, S.H, Pang, X.F. | 登録日 | 2018-12-04 | 公開日 | 2019-02-13 | 最終更新日 | 2019-02-27 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Double Lock of a Human Neutralizing and Protective Monoclonal Antibody Targeting the Yellow Fever Virus Envelope. Cell Rep, 26, 2019
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6IW0
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![BU of 6iw0 by Molmil](/molmil-images/mine/6iw0) | Crystal structure of 5A ScFv in complex with YFV-17D sE in postfusion state | 分子名称: | Envelope protein E, Heavy chain of monoclonal antibody 5A, Light chain of monoclonal antibody 5A | 著者 | Lu, X.S, Xiao, H.X, Li, S.H, Pang, X.F. | 登録日 | 2018-12-04 | 公開日 | 2019-02-13 | 最終更新日 | 2019-02-27 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | Double Lock of a Human Neutralizing and Protective Monoclonal Antibody Targeting the Yellow Fever Virus Envelope. Cell Rep, 26, 2019
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