3C91
| Thermoplasma acidophilum 20S proteasome with an open gate | 分子名称: | Proteasome subunit alpha, Proteasome subunit beta | 著者 | Rabl, J, Smith, D.M, Yu, Y, Chang, S.C, Goldberg, A.L, Cheng, Y. | 登録日 | 2008-02-14 | 公開日 | 2008-08-05 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (6.8 Å) | 主引用文献 | Mechanism of gate opening in the 20S proteasome by the proteasomal ATPases. Mol.Cell, 30, 2008
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5A5B
| Structure of the 26S proteasome-Ubp6 complex | 分子名称: | 26S PROTEASE REGULATORY SUBUNIT 4 HOMOLOG, 26S PROTEASE REGULATORY SUBUNIT 6A, 26S PROTEASE REGULATORY SUBUNIT 6B HOMOLOG, ... | 著者 | Aufderheide, A, Beck, F, Stengel, F, Hartwig, M, Schweitzer, A, Pfeifer, G, Goldberg, A.L, Sakata, E, Baumeister, W, Foerster, F. | 登録日 | 2015-06-17 | 公開日 | 2015-07-22 | 最終更新日 | 2017-08-30 | 実験手法 | ELECTRON MICROSCOPY (9.5 Å) | 主引用文献 | Structural Characterization of the Interaction of Ubp6 with the 26S Proteasome. Proc.Natl.Acad.Sci.USA, 112, 2015
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3C92
| Thermoplasma acidophilum 20S proteasome with a closed gate | 分子名称: | Proteasome subunit alpha, Proteasome subunit beta | 著者 | Rabl, J, Smith, D.M, Yu, Y, Chang, S.C, Goldberg, A.L, Cheng, Y. | 登録日 | 2008-02-14 | 公開日 | 2008-08-05 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (6.8 Å) | 主引用文献 | Mechanism of gate opening in the 20S proteasome by the proteasomal ATPases. Mol.Cell, 30, 2008
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3IPM
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5E0S
| crystal structure of the active form of the proteolytic complex clpP1 and clpP2 | 分子名称: | ATP-dependent Clp protease proteolytic subunit 1, ATP-dependent Clp protease proteolytic subunit 2 | 著者 | LI, M, Wlodawer, A, Maurizi, M. | 登録日 | 2015-09-29 | 公開日 | 2016-02-17 | 最終更新日 | 2016-04-13 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structure and Functional Properties of the Active Form of the Proteolytic Complex, ClpP1P2, from Mycobacterium tuberculosis. J.Biol.Chem., 291, 2016
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5DZK
| Crystal structure of the active form of the proteolytic complex clpP1 and clpP2 | 分子名称: | ATP-dependent Clp protease proteolytic subunit 1, ATP-dependent Clp protease proteolytic subunit 2, BEZ-LEU-LEU | 著者 | LI, M, Wlodawer, A, Maurizi, M. | 登録日 | 2015-09-25 | 公開日 | 2016-02-17 | 最終更新日 | 2016-04-13 | 実験手法 | X-RAY DIFFRACTION (3.07 Å) | 主引用文献 | Structure and Functional Properties of the Active Form of the Proteolytic Complex, ClpP1P2, from Mycobacterium tuberculosis. J.Biol.Chem., 291, 2016
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3MDJ
| ER Aminopeptidase, ERAP1, Bound to the Zinc Aminopeptidase Inhibitor, Bestatin | 分子名称: | 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Nguyen, T.T, Stern, L.J. | 登録日 | 2010-03-30 | 公開日 | 2011-03-30 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Structural basis for antigenic peptide precursor processing by the endoplasmic reticulum aminopeptidase ERAP1. Nat.Struct.Mol.Biol., 18, 2011
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6VGQ
| ClpP1P2 complex from M. tuberculosis with GLF-CMK bound to ClpP1 | 分子名称: | ATP-dependent Clp protease proteolytic subunit, ATP-dependent Clp protease proteolytic subunit 1, Z-Gly-leu-phe-CH2Cl | 著者 | Ripstein, Z.A, Vahidi, S, Rubinstein, J.L, Kay, L.E. | 登録日 | 2020-01-08 | 公開日 | 2020-03-18 | 最終更新日 | 2024-10-09 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | An allosteric switch regulatesMycobacterium tuberculosisClpP1P2 protease function as established by cryo-EM and methyl-TROSY NMR. Proc.Natl.Acad.Sci.USA, 117, 2020
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6VGK
| ClpP1P2 complex from M. tuberculosis | 分子名称: | ATP-dependent Clp protease proteolytic subunit 1, ATP-dependent Clp protease proteolytic subunit 2 | 著者 | Ripstein, Z.A, Vahidi, S, Rubinstein, J.L, Kay, L.E. | 登録日 | 2020-01-08 | 公開日 | 2020-03-18 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | An allosteric switch regulatesMycobacterium tuberculosisClpP1P2 protease function as established by cryo-EM and methyl-TROSY NMR. Proc.Natl.Acad.Sci.USA, 117, 2020
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7QXN
| Proteasome-ZFAND5 Complex Z+A state | 分子名称: | 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... | 著者 | Zhu, Y, Lu, Y. | 登録日 | 2022-01-26 | 公開日 | 2023-02-08 | 最終更新日 | 2024-09-04 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Molecular mechanism for activation of the 26S proteasome by ZFAND5. Mol.Cell, 83, 2023
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7QYA
| Proteasome-ZFAND5 Complex Z-B state | 分子名称: | 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... | 著者 | Zhu, Y, Lu, Y. | 登録日 | 2022-01-27 | 公開日 | 2023-02-08 | 最終更新日 | 2024-10-23 | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | 主引用文献 | Molecular mechanism for activation of the 26S proteasome by ZFAND5. Mol.Cell, 83, 2023
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7QXP
| Proteasome-ZFAND5 Complex Z+B state | 分子名称: | 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... | 著者 | Zhu, Y, Lu, Y. | 登録日 | 2022-01-26 | 公開日 | 2023-02-08 | 最終更新日 | 2024-09-04 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Molecular mechanism for activation of the 26S proteasome by ZFAND5. Mol.Cell, 83, 2023
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7QXX
| Proteasome-ZFAND5 Complex Z+E state | 分子名称: | 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, 26S protease regulatory subunit 7, ... | 著者 | Zhu, Y, Lu, Y. | 登録日 | 2022-01-27 | 公開日 | 2023-02-08 | 最終更新日 | 2024-11-06 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Molecular mechanism for activation of the 26S proteasome by ZFAND5. Mol.Cell, 83, 2023
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7QYB
| Proteasome-ZFAND5 Complex Z-C state | 分子名称: | 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... | 著者 | Zhu, Y, Lu, Y. | 登録日 | 2022-01-27 | 公開日 | 2023-02-08 | 最終更新日 | 2024-09-04 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Molecular mechanism for activation of the 26S proteasome by ZFAND5. Mol.Cell, 83, 2023
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7QY7
| Proteasome-ZFAND5 Complex Z-A state | 分子名称: | 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... | 著者 | Zhu, Y, Lu, Y. | 登録日 | 2022-01-27 | 公開日 | 2023-02-08 | 最終更新日 | 2024-09-04 | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | 主引用文献 | Molecular mechanism for activation of the 26S proteasome by ZFAND5. Mol.Cell, 83, 2023
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7QXW
| Proteasome-ZFAND5 Complex Z+D state | 分子名称: | 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, 26S protease regulatory subunit 7, ... | 著者 | Zhu, Y, Lu, Y. | 登録日 | 2022-01-27 | 公開日 | 2023-02-08 | 最終更新日 | 2024-10-16 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Molecular mechanism for activation of the 26S proteasome by ZFAND5. Mol.Cell, 83, 2023
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7QXU
| Proteasome-ZFAND5 Complex Z+C state | 分子名称: | 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, 26S protease regulatory subunit 7, ... | 著者 | Zhu, Y, Lu, Y. | 登録日 | 2022-01-27 | 公開日 | 2023-02-08 | 最終更新日 | 2024-11-06 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Molecular mechanism for activation of the 26S proteasome by ZFAND5. Mol.Cell, 83, 2023
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6VGN
| ClpP1P2 complex from M. tuberculosis bound to ADEP | 分子名称: | ATP-dependent Clp protease proteolytic subunit, ATP-dependent Clp protease proteolytic subunit 1, R0M-WFP-ALO-PRO-YCP-ALA-MP8 | 著者 | Ripstein, Z.A, Vahidi, S, Rubinstein, J.L, Kay, L.E. | 登録日 | 2020-01-08 | 公開日 | 2020-03-18 | 最終更新日 | 2020-04-01 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | An allosteric switch regulatesMycobacterium tuberculosisClpP1P2 protease function as established by cryo-EM and methyl-TROSY NMR. Proc.Natl.Acad.Sci.USA, 117, 2020
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2FZP
| Crystal structure of the USP8 interaction domain of human NRDP1 | 分子名称: | ring finger protein 41 isoform 1 | 著者 | Walker, J.R, Avvakumov, G.V, Xue, S, Newman, E.M, Butler-Cole, C, Finerty Jr, P.J, Weigelt, J, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | 登録日 | 2006-02-10 | 公開日 | 2006-03-28 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | Amino-terminal Dimerization, NRDP1-Rhodanese Interaction, and Inhibited Catalytic Domain Conformation of the Ubiquitin-specific Protease 8 (USP8). J.Biol.Chem., 281, 2006
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1DO0
| ORTHORHOMBIC CRYSTAL FORM OF HEAT SHOCK LOCUS U (HSLU) FROM ESCHERICHIA COLI | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PROTEIN (HEAT SHOCK LOCUS U), ... | 著者 | Bochtler, M, Hartmann, C, Song, H.K, Bourenkov, G.P, Bartunik, H.D. | 登録日 | 1999-12-18 | 公開日 | 2000-02-18 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | The structures of HsIU and the ATP-dependent protease HsIU-HsIV. Nature, 403, 2000
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1DO2
| TRIGONAL CRYSTAL FORM OF HEAT SHOCK LOCUS U (HSLU) FROM ESCHERICHIA COLI | 分子名称: | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, PROTEIN (HEAT SHOCK LOCUS U) | 著者 | Bochtler, M, Hartmann, C, Song, H.K, Bourenkov, G.P, Bartunik, H.D. | 登録日 | 1999-12-18 | 公開日 | 2000-02-18 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (4 Å) | 主引用文献 | The structures of HsIU and the ATP-dependent protease HsIU-HsIV. Nature, 403, 2000
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1G4B
| CRYSTAL STRUCTURES OF THE HSLVU PEPTIDASE-ATPASE COMPLEX REVEAL AN ATP-DEPENDENT PROTEOLYSIS MECHANISM | 分子名称: | ATP-DEPENDENT HSL PROTEASE ATP-BINDING SUBUNIT HSLU, ATP-DEPENDENT PROTEASE HSLV | 著者 | Wang, J, Song, J.J, Franklin, M.C, Kamtekar, S, Im, Y.J, Rho, S.H, Seong, I.S, Lee, C.S, Chung, C.H, Eom, S.H. | 登録日 | 2000-10-26 | 公開日 | 2001-02-21 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (7 Å) | 主引用文献 | Crystal structures of the HslVU peptidase-ATPase complex reveal an ATP-dependent proteolysis mechanism. Structure, 9, 2001
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1E94
| HslV-HslU from E.coli | 分子名称: | HEAT SHOCK PROTEIN HSLU, HEAT SHOCK PROTEIN HSLV, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | 著者 | Song, H.K, Hartmann, C, Ravishankar, R, Bochtler, M. | 登録日 | 2000-10-07 | 公開日 | 2000-11-17 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Mutational Studies on Hslu and its Docking Mode with Hslv Proc.Natl.Acad.Sci.USA, 97, 2000
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1G4A
| CRYSTAL STRUCTURES OF THE HSLVU PEPTIDASE-ATPASE COMPLEX REVEAL AN ATP-DEPENDENT PROTEOLYSIS MECHANISM | 分子名称: | 2'-DEOXYADENOSINE-5'-DIPHOSPHATE, ATP-DEPENDENT HSL PROTEASE ATP-BINDING SUBUNIT HSLU, ATP-DEPENDENT PROTEASE HSLV | 著者 | Wang, J, Song, J.J, Franklin, M.C, Kamtekar, S, Im, Y.J, Rho, S.H, Seong, I.S, Lee, C.S, Chung, C.H, Eom, S.H. | 登録日 | 2000-10-26 | 公開日 | 2001-02-21 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal structures of the HslVU peptidase-ATPase complex reveal an ATP-dependent proteolysis mechanism. Structure, 9, 2001
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