4RKO
| Crystal structure of thrombin mutant S195T bound with PPACK | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, ... | 著者 | Pelc, A.L, Chen, Z, Gohara, D.W, Vogt, A.D, Pozzi, N, Di Cera, E. | 登録日 | 2014-10-13 | 公開日 | 2015-03-11 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | Why ser and not thr brokers catalysis in the trypsin fold. Biochemistry, 54, 2015
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4R0E
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2IJD
| Crystal Structure of the Poliovirus Precursor Protein 3CD | 分子名称: | Picornain 3C, RNA-directed RNA polymerase, SULFATE ION, ... | 著者 | Marcotte, L.L, Gohara, D.W, Filman, D.J, Hogle, J.M. | 登録日 | 2006-09-29 | 公開日 | 2007-02-13 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Crystal structure of poliovirus 3CD: virally-encoded protease and precursor to the RNA-dependent RNA polymerase. J.Virol., 81, 2007
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4RKJ
| Crystal structure of thrombin mutant S195T (free form) | 分子名称: | GLYCEROL, POTASSIUM ION, Thrombin heavy chain, ... | 著者 | Pelc, A.L, Chen, Z, Gohara, D.W, Vogt, A.D, Pozzi, N, Di Cera, E. | 登録日 | 2014-10-13 | 公開日 | 2015-03-11 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Why ser and not thr brokers catalysis in the trypsin fold. Biochemistry, 54, 2015
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4HZH
| Structure of recombinant Gla-domainless prothrombin mutant S525A | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Prothrombin | 著者 | Pozzi, N, Niu, W, Gohara, D.W, Chen, Z, Di Cera, E. | 登録日 | 2012-11-15 | 公開日 | 2013-06-26 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Crystal structure of prothrombin reveals conformational flexibility and mechanism of activation. J.Biol.Chem., 288, 2013
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2IJF
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5JDU
| Crystal structure for human thrombin mutant D189A | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GLYCEROL, ... | 著者 | Pozzi, N, Chen, Z, Di Cera, E. | 登録日 | 2016-04-17 | 公開日 | 2016-07-13 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Loop Electrostatics Asymmetry Modulates the Preexisting Conformational Equilibrium in Thrombin. Biochemistry, 55, 2016
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