5JCG
 
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3L21
 | | The crystal structure of a dimeric mutant of dihydrodipicolinate synthase (DAPA, RV2753C) from Mycobacterium Tuberculosis - DHDPS-A204R | | 分子名称: | ACETATE ION, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... | | 著者 | Evans, G.L, Schuldt, L, Jamerson, G.B, Devenish, S.R, Weiss, M.S, Gerrard, J.A. | | 登録日 | 2009-12-14 | | 公開日 | 2010-12-15 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | A dimeric mutant of DHDPS from Mycobacterium tuberculosis
To be Published
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4OY5
 | | 0.89 Angstrom resolution crystal structure of (Gly-Pro-Hyp)10 | | 分子名称: | Collagen | | 著者 | Suzuki, H, Mahapatra, D, Steel, P.J, Dyer, J, Dobson, R.C.J, Gerrard, J.A, Valery, C. | | 登録日 | 2014-02-10 | | 公開日 | 2015-03-04 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (0.89 Å) | | 主引用文献 | Sub-angstrom structure of the collagen model peptide (GPO)10 shows a hydrated triple helix with pitch variation and two proline ring conformations
To Be Published
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2OJP
 | | The crystal structure of a dimeric mutant of Dihydrodipicolinate synthase from E.coli- DHDPS-L197Y | | 分子名称: | Dihydrodipicolinate synthase, GLYCEROL | | 著者 | Griffin, M.D.W, Dobson, R.C.J, Antonio, L, Perugini, M.A, Jameson, G.B, Gerrard, J.A. | | 登録日 | 2007-01-13 | | 公開日 | 2008-01-01 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Evolution of quaternary structure in a homotetrameric enzyme.
J.Mol.Biol., 380, 2008
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2PUR
 | | Structure of dihydrodipicolinate synthase mutant Thr44Ser at 1.7 A. | | 分子名称: | Dihydrodipicolinate synthase, GLYCEROL, PHOSPHATE ION, ... | | 著者 | Dobson, R.C.J, Jameson, G.B, Gerrard, J.A. | | 登録日 | 2007-05-09 | | 公開日 | 2008-05-27 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Specificity versus catalytic potency: The role of threonine 44 in Escherichia coli dihydrodipicolinate synthase mediated catalysis.
Biochimie, 91, 2009
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5UCX
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3DEN
 | | Structure of E. coli DHDPS mutant Y107W | | 分子名称: | Dihydrodipicolinate synthase, GLYCEROL, PHOSPHATE ION, ... | | 著者 | Pearce, F.G, Gerrard, J.A, Perugini, M.A, Jameson, G.B. | | 登録日 | 2008-06-10 | | 公開日 | 2008-11-25 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Mutating the tight-dimer interface of dihydrodipicolinate synthase disrupts the enzyme quaternary structure: toward a monomeric enzyme
Biochemistry, 47, 2008
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3DU0
 | | E. coli dihydrodipicolinate synthase with first substrate, pyruvate, bound in active site | | 分子名称: | CHLORIDE ION, Dihydrodipicolinate synthase, GLYCEROL, ... | | 著者 | Dobson, R.C.J, Devenish, S.R.A, Gerrard, J.A, Jameson, G.B. | | 登録日 | 2008-07-16 | | 公開日 | 2008-11-18 | | 最終更新日 | 2019-12-18 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The high-resolution structure of dihydrodipicolinate synthase from Escherichia coli bound to its first substrate, pyruvate.
Acta Crystallogr.,Sect.F, 64, 2008
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3DAQ
 | | Crystal structure of dihydrodipicolinate synthase from methicillin-resistant Staphylococcus aureus | | 分子名称: | CHLORIDE ION, Dihydrodipicolinate synthase, GLYCEROL | | 著者 | Dobson, R.C.J, Burgess, B.R, Jameson, G.B, Gerrard, J.A, Parker, M.W, Perugini, M.A. | | 登録日 | 2008-05-29 | | 公開日 | 2008-08-05 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Structure and evolution of a novel dimeric enzyme from a clinically-important bacterial pathogen.
J.Biol.Chem., 2008
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1S5T
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1S5V
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1S5W
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3I7Q
 | | Dihydrodipicolinate synthase mutant - K161A | | 分子名称: | Dihydrodipicolinate synthase, GLYCEROL, PHOSPHATE ION, ... | | 著者 | Dobson, R.C.J, Jameson, G.B, Gerrard, J.A, Soares da Costa, T.P. | | 登録日 | 2009-07-08 | | 公開日 | 2010-04-14 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | How essential is the 'essential' active-site lysine in dihydrodipicolinate synthase?
Biochimie, 92, 2010
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3I7R
 | | Dihydrodipicolinate synthase - K161R | | 分子名称: | CHLORIDE ION, Dihydrodipicolinate synthase, GLYCEROL, ... | | 著者 | Dobson, R.C.J, Jameson, G.B, Gerrard, J.A, Soares da Costa, T.P. | | 登録日 | 2009-07-08 | | 公開日 | 2010-04-14 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | How essential is the 'essential' active-site lysine in dihydrodipicolinate synthase?
Biochimie, 92, 2010
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3I7S
 | | Dihydrodipicolinate synthase mutant - K161A - with the substrate pyruvate bound in the active site. | | 分子名称: | Dihydrodipicolinate synthase, GLYCEROL, PHOSPHATE ION, ... | | 著者 | Dobson, R.C.J, Jameson, G.B, Gerrard, J.A, Soares da Costa, T.P. | | 登録日 | 2009-07-08 | | 公開日 | 2010-04-14 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | How essential is the 'essential' active-site lysine in dihydrodipicolinate synthase?
Biochimie, 92, 2010
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2A6N
 | | Dihydrodipicolinate synthase (E. coli)- mutant R138A | | 分子名称: | Dihydrodipicolinate synthase, POTASSIUM ION | | 著者 | Dobson, R.C, Devenish, S.R, Turner, L.A, Clifford, V.R, Pearce, F.G, Jameson, G.B, Gerrard, J.A. | | 登録日 | 2005-07-03 | | 公開日 | 2005-10-18 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Role of Arginine 138 in the Catalysis and Regulation of Escherichia coli Dihydrodipicolinate Synthase.
Biochemistry, 44, 2005
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1YXC
 | | Structure of E. coli dihydrodipicolinate synthase to 1.9 A | | 分子名称: | CHLORIDE ION, POTASSIUM ION, dihydrodipicolinate synthase | | 著者 | Dobson, R.C.J, Griffin, M.D.W, Jameson, G.B, Gerrard, J.A. | | 登録日 | 2005-02-20 | | 公開日 | 2005-08-02 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The crystal structures of native and (S)-lysine-bound dihydrodipicolinate synthase from Escherichia coli with improved resolution show new features of biological significance.
Acta Crystallogr.,Sect.D, 61, 2005
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2ATS
 | | Dihydrodipicolinate synthase co-crystallised with (S)-lysine | | 分子名称: | CHLORIDE ION, D-LYSINE, POTASSIUM ION, ... | | 著者 | Devenish, S.R.A, Dobson, R.C.J, Jameson, G.B, Gerrard, J.A. | | 登録日 | 2005-08-26 | | 公開日 | 2006-09-19 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The co-crystallisation of (S)-lysine-bound dihydrodipicolinate synthase from E. coli indicates that domain movements are not responsible for (S)-lysine inhibition
To be published
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1YXD
 | | Structure of E. coli dihydrodipicolinate synthase bound with allosteric inhibitor (S)-lysine to 2.0 A | | 分子名称: | CHLORIDE ION, LYSINE, POTASSIUM ION, ... | | 著者 | Dobson, R.C.J, Griffin, M.D.W, Jameson, G.B, Gerrard, J.A. | | 登録日 | 2005-02-20 | | 公開日 | 2005-08-02 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The crystal structures of native and (S)-lysine-bound dihydrodipicolinate synthase from Escherichia coli with improved resolution show new features of biological significance.
Acta Crystallogr.,Sect.D, 61, 2005
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2A6L
 | | Dihydrodipicolinate synthase (E. coli)- mutant R138H | | 分子名称: | Dihydrodipicolinate synthase, POTASSIUM ION | | 著者 | Dobson, R.C, Devenish, S.R, Turner, L.A, Clifford, V.R, Pearce, F.G, Jameson, G.B, Gerrard, J.A. | | 登録日 | 2005-07-03 | | 公開日 | 2005-10-18 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Role of Arginine 138 in the Catalysis and Regulation of Escherichia coli Dihydrodipicolinate Synthase.
Biochemistry, 44, 2005
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4DPP
 | | The structure of dihydrodipicolinate synthase 2 from Arabidopsis thaliana | | 分子名称: | Dihydrodipicolinate synthase 2, chloroplastic, SODIUM ION | | 著者 | Griffin, M.D.W, Billakanti, J.M, Gerrard, J.A, Dobson, R.C.J, Pearce, F.G. | | 登録日 | 2012-02-14 | | 公開日 | 2012-07-18 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Characterisation of the first enzymes committed to lysine biosynthesis in Arabidopsis thaliana
Plos One, 7, 2012
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4DPQ
 | | The structure of dihydrodipicolinate synthase 2 from Arabidopsis thaliana in complex with (S)-lysine | | 分子名称: | Dihydrodipicolinate synthase 2, chloroplastic, LYSINE, ... | | 著者 | Griffin, M.D.W, Billakanti, J.M, Gerrard, J.A, Dobson, R.C.J, Pearce, F.G. | | 登録日 | 2012-02-14 | | 公開日 | 2012-07-18 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.202 Å) | | 主引用文献 | Characterisation of the first enzymes committed to lysine biosynthesis in Arabidopsis thaliana
Plos One, 7, 2012
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3HIJ
 | | Crystal structure of dihydrodipicolinate synthase from Bacillus anthracis in complex with its substrate, pyruvate | | 分子名称: | Dihydrodipicolinate synthase, GLYCEROL, SODIUM ION | | 著者 | Voss, J.E, Scally, S.W, Dobson, R.C.J, Perugini, M.A. | | 登録日 | 2009-05-20 | | 公開日 | 2009-11-24 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Substrate-mediated Stabilization of a Tetrameric Drug Target Reveals Achilles Heel in Anthrax.
J.Biol.Chem., 285, 2010
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3TUU
 | | Structure of dihydrodipicolinate synthase from the common grapevine | | 分子名称: | BROMIDE ION, CHLORIDE ION, dihydrodipicolinate synthase | | 著者 | Perugini, M.A, Dobson, R.C, Atkinson, S.C. | | 登録日 | 2011-09-19 | | 公開日 | 2012-07-25 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal, Solution and In silico Structural Studies of Dihydrodipicolinate Synthase from the Common Grapevine.
Plos One, 7, 2012
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3VFL
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