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1Q5X
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BU of 1q5x by Molmil
Structure of OF RRAA (MENG), a protein inhibitor of RNA processing
分子名称: REGULATOR OF RNASE E ACTIVITY A
著者Monzingo, A.F, Gao, J, Qiu, J, Georgiou, G, Robertus, J.D.
登録日2003-08-11
公開日2003-09-30
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The X-ray Structure of Escherichia coli RraA (MenG), A Protein Inhibitor of RNA Processing.
J.Mol.Biol., 332, 2003
1T3B
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BU of 1t3b by Molmil
X-ray Structure of DsbC from Haemophilus influenzae
分子名称: Thiol:disulfide interchange protein dsbC
著者Zhang, M, Monzingo, A.F, Segatori, L, Georgiou, G, Robertus, J.D.
登録日2004-04-26
公開日2004-09-07
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of DsbC from Haemophilus influenzae.
Acta Crystallogr.,Sect.D, 60, 2004
3ETB
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BU of 3etb by Molmil
Crystal structure of the engineered neutralizing antibody M18 complexed with anthrax protective antigen domain 4
分子名称: Anthrax Protective Antigen, Antibody M18 light chain and antibody M18 heavy chain linked with a synthetic (GGGGS)4 linker
著者Monzingo, A.F, Leysath, C.E, Barnett, J, Iverson, B.L, Georgiou, G, Robertus, J.D.
登録日2008-10-07
公開日2009-04-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Crystal structure of the engineered neutralizing antibody M18 complexed to domain 4 of the anthrax protective antigen.
J.Mol.Biol., 387, 2009
3ESU
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BU of 3esu by Molmil
Crystal structure of anthrax-neutralizing single-chain antibody 14b7
分子名称: Antibody 14b7* light chain and antibody 14b7* heavy chain linked with a synthetic (GGGGS)4 linker
著者Monzingo, A.F, Maynard, J.A, Iverson, B.L, Georgiou, G, Robertus, J.D.
登録日2008-10-06
公開日2009-04-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Crystal structure of the engineered neutralizing antibody m18 complexed to domain 4 of the anthrax protective antigen.
J.Mol.Biol., 387, 2009
3ET9
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BU of 3et9 by Molmil
Crystal structure of the engineered neutralizing antibody 1H
分子名称: Antibody 1H light chain and antibody 1H heavy chain linked with a synthetic (GGGGS)4 linker
著者Leysath, C.E, Monzingo, A.F, Barnett, J, Iverson, B.L, Georgiou, G, Robertus, J.D.
登録日2008-10-07
公開日2009-04-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of the engineered neutralizing antibody m18 complexed to domain 4 of the anthrax protective antigen.
J.Mol.Biol., 387, 2009
3ESV
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BU of 3esv by Molmil
Crystal structure of the engineered neutralizing antibody M18
分子名称: Antibody M18 light chain and antibody M18 heavy chain linked with a synthetic (GGGGS)4 linker
著者Monzingo, A.F, Leysath, C.E, Barnett, J, Iverson, B.L, Georgiou, G, Robertus, J.D.
登録日2008-10-06
公開日2009-04-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of the engineered neutralizing antibody m18 complexed to domain 4 of the anthrax protective antigen.
J.Mol.Biol., 387, 2009
3S7G
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BU of 3s7g by Molmil
Aglycosylated human igg1 fc fragment
分子名称: Ig gamma-1 chain C region
著者Borrok, M.J, Georgiou, G.
登録日2011-05-26
公開日2012-05-30
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.13 Å)
主引用文献Structural Analysis of an Aglycosylated Fc
To be Published
4OCS
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BU of 4ocs by Molmil
Crystal structure of human Fab CAP256-VRC26.10, a potent V1V2-directed HIV-1 neutralizing antibody
分子名称: CAP256-VRC26.10 heavy chain, CAP256-VRC26.10 light chain
著者Gorman, J, Doria-Rose, N.A, Schramm, C.A, Moore, P.L, Mascola, J.R, Shapiro, L, Morris, L, Kwong, P.D.
登録日2014-01-09
公開日2014-02-26
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.901 Å)
主引用文献Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies.
Nature, 509, 2014
4OCW
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BU of 4ocw by Molmil
Crystal structure of human Fab CAP256-VRC26.06, a potent V1V2-directed HIV-1 neutralizing antibody
分子名称: CAP256-VRC26.06 heavy chain, CAP256-VRC26.06 light chain
著者Gorman, J, Doria-Rose, N.A, Schramm, C.A, Moore, P.L, Mascola, J.R, Shapiro, L, Morris, L, Kwong, P.D.
登録日2014-01-09
公開日2014-02-26
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (3.001 Å)
主引用文献Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies.
Nature, 509, 2014
7M8J
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BU of 7m8j by Molmil
SARS-CoV-2 S-NTD + Fab CM25
分子名称: CM25 Fab - Heavy Chain, CM25 Fab - Light Chain, Spike protein S1
著者Johnson, N.V, Mclellan, J.S.
登録日2021-03-29
公開日2021-05-19
最終更新日2021-06-16
実験手法ELECTRON MICROSCOPY (3.48 Å)
主引用文献Prevalent, protective, and convergent IgG recognition of SARS-CoV-2 non-RBD spike epitopes.
Science, 372, 2021
4ET0
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BU of 4et0 by Molmil
Crystal structure of circularly permuted human asparaginase-like protein 1
分子名称: L-asparaginase, SODIUM ION
著者Li, W.Z, Yogesha, S.D, Zhang, Y.
登録日2012-04-23
公開日2012-09-26
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Uncoupling Intramolecular Processing and Substrate Hydrolysis in the N-Terminal Nucleophile Hydrolase hASRGL1 by Circular Permutation.
Acs Chem.Biol., 7, 2012
5IBU
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BU of 5ibu by Molmil
6652 Fab (unbound)
分子名称: 6652 Heavy Chain, 6652 Light Chain
著者Raymond, D.D, Harrison, S.C.
登録日2016-02-22
公開日2016-11-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Influenza immunization elicits antibodies specific for an egg-adapted vaccine strain.
Nat. Med., 22, 2016
5IBT
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BU of 5ibt by Molmil
UCA Fab (unbound) from 6515 Lineage
分子名称: GLYCEROL, UCA Heavy Chain, UCA Light Chain
著者Raymond, D.D, Harrison, S.C.
登録日2016-02-22
公開日2016-11-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Influenza immunization elicits antibodies specific for an egg-adapted vaccine strain.
Nat. Med., 22, 2016
5IBL
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BU of 5ibl by Molmil
Human antibody 6639 in complex with influenza hemagglutinin H1 X-181
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 6639 Heavy Chain, 6639 Light Chain, ...
著者Raymond, D.D, Harrison, S.C.
登録日2016-02-22
公開日2016-11-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.39 Å)
主引用文献Influenza immunization elicits antibodies specific for an egg-adapted vaccine strain.
Nat. Med., 22, 2016
6OVG
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BU of 6ovg by Molmil
L-Methionine Depletion with an Engineered Human Enzyme Disrupts Prostate Cancer Metabolism
分子名称: Cystathionine gamma-lyase, SULFATE ION
著者Yan, W, Irani, S, Zhang, J.
登録日2019-05-07
公開日2020-04-22
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.719 Å)
主引用文献Enzyme-mediated depletion of serum l-Met abrogates prostate cancer growth via multiple mechanisms without evidence of systemic toxicity.
Proc.Natl.Acad.Sci.USA, 117, 2020
6P79
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BU of 6p79 by Molmil
Engineered single chain antibody C9+C14 ScFv
分子名称: Engineered antibody heavy chain, Engineered antibody light chain
著者Zhang, Y, Li, W, Marshall, N.
登録日2019-06-05
公開日2020-04-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.583 Å)
主引用文献Computer-based Engineering of Thermostabilized Antibody Fragments.
Aiche J, 66, 2020
7S3V
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BU of 7s3v by Molmil
Structure of HsKYNase_66, an evolved variant of human kynureninase with greatly increased activity towards kynurenine
分子名称: Kynureninase
著者Burkholder, N.T, Zhang, Y.J.
登録日2021-09-08
公開日2022-12-21
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.249 Å)
主引用文献Bypassing evolutionary dead ends and switching the rate-limiting step of a human immunotherapeutic enzyme.
Nat Catal, 5, 2022
7KJP
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BU of 7kjp by Molmil
Disulfide Stabilized Norovirus GI.1 VLP Shell Region
分子名称: Capsid protein VP1
著者Gorman, J, Kwong, P.D.
登録日2020-10-26
公開日2020-12-02
最終更新日2020-12-30
実験手法ELECTRON MICROSCOPY (3.86 Å)
主引用文献Disulfide stabilization of human norovirus GI.1 virus-like particles focuses immune response toward blockade epitopes.
NPJ Vaccines, 5, 2020
8TMA
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BU of 8tma by Molmil
Antibody N3-1 bound to RBD in the up conformation
分子名称: N3-1 Fab heavy chain, N3-1 Fab light chain, Spike glycoprotein
著者Hsieh, C.-L, McLellan, J.S.
登録日2023-07-29
公開日2024-01-17
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献SARS-COV-2 Omicron variants conformationally escape a rare quaternary antibody binding mode.
Commun Biol, 6, 2023
8TM1
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BU of 8tm1 by Molmil
Antibody N3-1 bound to RBDs in the up and down conformations
分子名称: N3-1 Fab heavy chain, N3-1 Fab light chain, Spike glycoprotein
著者Hsieh, C.-L, McLellan, J.S.
登録日2023-07-27
公開日2024-01-17
実験手法ELECTRON MICROSCOPY (2.79 Å)
主引用文献SARS-COV-2 Omicron variants conformationally escape a rare quaternary antibody binding mode.
Commun Biol, 6, 2023
2E7P
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BU of 2e7p by Molmil
Crystal structure of the holo form of glutaredoxin C1 from populus tremula x tremuloides
分子名称: FE2/S2 (INORGANIC) CLUSTER, GLUTATHIONE, Glutaredoxin
著者Unno, H, Takahashi, T, Kawakami, T, Aimoto, S, Hase, T, Kusunoki, M, Rouhier, N, Jacquot, J.P.
登録日2007-01-12
公開日2007-09-25
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Functional, structural, and spectroscopic characterization of a glutathione-ligated [2Fe-2S] cluster in poplar glutaredoxin C1
Proc.Natl.Acad.Sci.Usa, 104, 2007
6MTO
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BU of 6mto by Molmil
Crystal structure of VRC42.01 Fab in complex with T117-F MPER scaffold
分子名称: Antibody VRC42.01 Fab heavy chain, Antibody VRC42.01 Fab light chain, VRC42 epitope T117-F scaffold
著者Kwon, Y.D, Druz, A, Law, W.H, Peng, D, Zhang, B, Doria-Rose, N.A, Kwong, P.D.
登録日2018-10-21
公開日2019-03-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.634 Å)
主引用文献Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual.
Immunity, 50, 2019
6MTR
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BU of 6mtr by Molmil
Crystal structure of VRC43.01 Fab
分子名称: Antibody VRC43.01 Fab heavy chain, Antibody VRC43.01 Fab light chain
著者Kwon, Y.D, Druz, A, Law, W.H, Peng, D, Zhang, B, Doria-Rose, N.A, Kwong, P.D.
登録日2018-10-21
公開日2019-03-27
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.798 Å)
主引用文献Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual.
Immunity, 50, 2019
6MTS
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BU of 6mts by Molmil
Crystal structure of VRC43.03 Fab
分子名称: Antibody VRC43.03 Fab heavy chain, Antibody VRC43.03 Fab light chain
著者Kwon, Y.D, Druz, A, Law, W.H, Peng, D, Doria-Rose, N.A, Kwong, P.D.
登録日2018-10-21
公開日2019-03-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.437 Å)
主引用文献Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual.
Immunity, 50, 2019
6MTP
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Crystal structure of VRC42.04 Fab in complex with gp41 peptide
分子名称: Antibody VRC42.04 Fab heavy chain, Antibody VRC42.04 Fab light chain, RV217 founder virus gp41 peptide
著者Kwon, Y.D, Druz, A, Law, W.H, Peng, D, Zhang, B, Doria-Rose, N.A, Kwong, P.D.
登録日2018-10-21
公開日2019-03-27
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.036 Å)
主引用文献Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual.
Immunity, 50, 2019

 

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