1H15
 
 | | X-ray crystal structure of HLA-DRA1*0101/DRB5*0101 complexed with a peptide from Epstein Barr Virus DNA polymerase | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DNA POLYMERASE, ... | | 著者 | Lang, H, Jacobsen, H, Ikemizu, S, Andersson, C, Harlos, K, Madsen, L, Hjorth, P, Sondergaard, L, Svejgaard, A, Wucherpfennig, K, Stuart, D.I, Bell, J.I, Jones, E.Y, Fugger, L. | | 登録日 | 2002-07-02 | | 公開日 | 2002-10-03 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | A Functional and Structural Basis for Tcr Cross-Reactivity in Multiple Sclerosis
Nat.Immunol., 3, 2002
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1UVQ
 | | Crystal structure of HLA-DQ0602 in complex with a hypocretin peptide | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETIC ACID, GLYCINE, ... | | 著者 | Siebold, C, Hansen, B.E, Wyer, J.R, Harlos, K, Esnouf, R.E, Svejgaard, A, Bell, J.I, Strominger, J.L, Jones, E.Y, Fugger, L. | | 登録日 | 2004-01-22 | | 公開日 | 2004-02-05 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal Structure of Hla-Dq0602 that Protects Against Type 1 Diabetes and Confers Strong Susceptibility to Narcolepsy
Proc.Natl.Acad.Sci.USA, 101, 2004
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2XPG
 | | Crystal structure of a MHC class I-peptide complex | | 分子名称: | BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-3 ALPHA CHAIN, ... | | 著者 | McMahon, R.M, Friis, L, Siebold, C, Friese, M.A, Fugger, L, Jones, E.Y. | | 登録日 | 2010-08-26 | | 公開日 | 2011-04-27 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure of Hla-A0301 in Complex with a Peptide of Proteolipid Protein: Insights Into the Role of Hla-A Alleles in Susceptibility to Multiple Sclerosis
Acta Crystallogr.,Sect.D, 67, 2011
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3MFF
 | | 1F1E8hu TCR | | 分子名称: | ARGININE, GLYCEROL, T cell receptor alpha chain, ... | | 著者 | van Boxel, G.I, Holmes, S, Fugger, L, Jones, E.Y. | | 登録日 | 2010-04-02 | | 公開日 | 2010-06-02 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | An alternative conformation of the T-cell receptor alpha constant region
J.Mol.Biol., 400, 2010
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6VQ2
 | | HLA-B*27:05 presenting an HIV-1 14mer peptide | | 分子名称: | 14-mer peptide, Beta-2-microglobulin, GLYCEROL, ... | | 著者 | Pymm, P, Tenzer, S, Wee, E, Weimershaus, M, Burgevin, A, Kollnberger, S, Gerstoft, J, Josephs, T.M, Ladell, K, Mclaren, J.E, Appay, V, Price, D.A, Fugger, L, Bell, J.I, Hansjorg, S, Van Endert, P, Harkiolaki, M, Iversen, A.K.N. | | 登録日 | 2020-02-04 | | 公開日 | 2021-02-10 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Epitope length variants balance protective immune responses and viral escape in HIV-1 infection
Cell Rep, 38, 2022
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6VQE
 | | HLA-B*27:05 presenting an HIV-1 13mer peptide | | 分子名称: | 13-mer peptide, Beta-2-microglobulin, GLYCEROL, ... | | 著者 | Pymm, P, Tenzer, S, Wee, E, Weimershaus, M, Burgevin, A, Kollnberger, S, Gerstoft, J, Josephs, T.M, Ladell, K, Mclaren, J.E, Appay, V, Price, D.A, Fugger, L, Bell, J.I, Hansjorg, S, Van Endert, P, Harkiolaki, M, Iversen, A.K.N. | | 登録日 | 2020-02-05 | | 公開日 | 2021-02-10 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | Epitope length variants balance protective immune responses and viral escape in HIV-1 infection
Cell Rep, 38, 2022
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6VQD
 | | HLA-B*27:05 presenting an HIV-1 8mer peptide | | 分子名称: | 8-mer peptide, Beta-2-microglobulin, GLYCEROL, ... | | 著者 | Pymm, P, Tenzer, S, Wee, E, Weimershaus, M, Burgevin, A, Kollnberger, S, Gerstoft, J, Josephs, T.M, Ladell, K, Mclaren, J.E, Appay, V, Price, D.A, Fugger, L, Bell, J.I, Hansjorg, S, Van Endert, P, Harkiolaki, M, Iversen, A.K.N. | | 登録日 | 2020-02-05 | | 公開日 | 2021-02-10 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | | 主引用文献 | Epitope length variants balance protective immune responses and viral escape in HIV-1 infection
Cell Rep, 38, 2022
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6VQY
 | | HLA-B*27:05 presenting an HIV-1 7mer peptide | | 分子名称: | 7-mer peptide, ARGININE, Beta-2-microglobulin, ... | | 著者 | Pymm, P, Tenzer, S, Wee, E, Weimershaus, M, Burgevin, A, Kollnberger, S, Gerstoft, J, Josephs, T.M, Ladell, K, Mclaren, J.E, Appay, V, Price, D.A, Fugger, L, Bell, J.I, Hansjorg, S, Van Endert, P, Harkiolaki, M, Iversen, A.K.N. | | 登録日 | 2020-02-06 | | 公開日 | 2021-02-10 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | | 主引用文献 | Epitope length variants balance protective immune responses and viral escape in HIV-1 infection
Cell Rep, 38, 2022
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6VQZ
 | | HLA-B*27:05 presenting an HIV-1 6mer peptide | | 分子名称: | 6-mer peptide, ARGININE, Beta-2-microglobulin, ... | | 著者 | Pymm, P, Tenzer, S, Wee, E, Weimershaus, M, Burgevin, A, Kollnberger, S, Gerstoft, J, Josephs, T.M, Ladell, K, Mclaren, J.E, Appay, V, Price, D.A, Fugger, L, Bell, J.I, Hansjorg, S, Van Endert, P, Harkiolaki, M, Iversen, A.K.N. | | 登録日 | 2020-02-06 | | 公開日 | 2021-02-10 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Epitope length variants balance protective immune responses and viral escape in HIV-1 infection
Cell Rep, 38, 2022
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6VPZ
 | | HLA-B*27:05 presenting an HIV-1 11mer peptide | | 分子名称: | 11-mer peptide, Beta-2-microglobulin, GLYCEROL, ... | | 著者 | Pymm, P, Tenzer, S, Wee, E, Weimershaus, M, Burgevin, A, Kollnberger, S, Gerstoft, J, Josephs, T.M, Ladell, K, Mclaren, J.E, Appay, V, Price, D.A, Fugger, L, Bell, J.I, Hansjorg, S, Van Endert, P, Harkiolaki, M, Iversen, A.K.N. | | 登録日 | 2020-02-04 | | 公開日 | 2021-02-10 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Epitope length variants balance protective immune responses and viral escape in HIV-1 infection
Cell Rep, 38, 2022
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2WBJ
 | | TCR complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN, ... | | 著者 | Harkiolaki, M, Holmes, S.L, Svendsen, P, Gregersen, J.W, Jensen, L.T, McMahon, R, Friese, M.A, van Boxel, G, Etzensperger, R, Tzartos, J.S, Kranc, K, Sainsbury, S, Harlos, K, Mellins, E.D, Palace, J, Esiri, M.M, van der Merwe, P.A, Jones, E.Y, Fugger, L. | | 登録日 | 2009-03-02 | | 公開日 | 2009-04-07 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | T Cell-Mediated Autoimmune Disease due to Low-Affinity Crossreactivity to Common Microbial Peptides.
Immunity, 30, 2009
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2C7U
 | | Conflicting selective forces affect CD8 T-cell receptor contact sites in an HLA-A2 immunodominant HIV epitope. | | 分子名称: | BETA-2-MICROGLOBULIN, GAG PROTEIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ... | | 著者 | Iversen, A.K, Stewart-Jones, G, Learn, G.H, Christie, N, Sylvester-Hviid, C, Armitage, A.E, Kaul, R, Beattie, T, Lee, J.K, Li, Y, Chotiyarnwong, P, Dong, T, Xu, X, Luscher, M.A, MacDonald, K, Ullum, H, Klarlund-Pedersen, B, Skinhoj, P, Fugger, J.L, Buus, S, Mullins, J.I, Jones, E.Y, van der Merwe, P.A, McMichael, A.J. | | 登録日 | 2005-11-29 | | 公開日 | 2006-03-08 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | | 主引用文献 | Conflicting Selective Forces Affect T Cell Receptor Contacts in an Immunodominant Human Immunodeficiency Virus Epitope.
Nat.Immunol., 7, 2006
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5HEZ
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8EQ6
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5VGE
 | | Crystal structure of HLA-C*07:02 in complex with RYR peptide | | 分子名称: | ARG-TYR-ARG-PRO-GLY-THR-VAL-ALA-LEU, Beta-2-microglobulin, ZINC ION, ... | | 著者 | Mobbs, J.I, Vivian, J.P, Gras, S, Rossjohn, J. | | 登録日 | 2017-04-11 | | 公開日 | 2017-06-07 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural and regulatory diversity shape HLA-C protein expression levels.
Nat Commun, 8, 2017
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5VGD
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3GIV
 | | Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance | | 分子名称: | Beta-2-microglobulin, HIV-1 peptide, HLA class I histocompatibility antigen, ... | | 著者 | Stewart-Jones, G, Iversen, A.K.N, Jones, E.Y. | | 登録日 | 2009-03-06 | | 公開日 | 2009-06-30 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance
Nat.Immunol., 10, 2009
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5V4N
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5V4M
 | | Structure of HLA-DR15 with bound alpha3(135-145) peptide | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HLA-DRA1, ... | | 著者 | Petersen, J, Rossjohn, J. | | 登録日 | 2017-03-10 | | 公開日 | 2017-05-03 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells.
Nature, 545, 2017
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