1LQU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1lqu by Molmil](/molmil-images/mine/1lqu) | Mycobacterium tuberculosis FprA in complex with NADPH | 分子名称: | ACETATE ION, FLAVIN-ADENINE DINUCLEOTIDE, FprA, ... | 著者 | Bossi, R.T, Aliverti, A, Raimondi, D, Fischer, F, Zanetti, G, Ferrari, D, Tahallah, N, Maier, C.S, Heck, A.J.R, Rizzi, M, Mattevi, A, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2002-05-13 | 公開日 | 2002-07-31 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | A covalent modification of NADP+ revealed by the atomic resolution structure of FprA, a Mycobacterium tuberculosis oxidoreductase. Biochemistry, 41, 2002
|
|
1LQT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1lqt by Molmil](/molmil-images/mine/1lqt) | A covalent modification of NADP+ revealed by the atomic resolution structure of FprA, a Mycobacterium tuberculosis oxidoreductase | 分子名称: | 4-OXO-NICOTINAMIDE-ADENINE DINUCLEOTIDE PHOSPHATE, ACETATE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... | 著者 | Bossi, R.T, Aliverti, A, Raimondi, D, Fischer, F, Zanetti, G, Ferrari, D, Tahallah, N, Maier, C.S, Heck, A.J.R, Rizzi, M, Mattevi, A, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2002-05-13 | 公開日 | 2002-07-31 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | 主引用文献 | A covalent modification of NADP+ revealed by the atomic resolution structure of FprA, a Mycobacterium tuberculosis oxidoreductase. Biochemistry, 41, 2002
|
|
3C75
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3c75 by Molmil](/molmil-images/mine/3c75) | Paracoccus versutus methylamine dehydrogenase in complex with amicyanin | 分子名称: | Amicyanin, COPPER (II) ION, Methylamine dehydrogenase heavy chain, ... | 著者 | Cavalieri, C, Biermann, N, Vlasie, M.D, Einsle, O, Merli, A, Ferrari, D, Rossi, G.L, Ubbink, M. | 登録日 | 2008-02-06 | 公開日 | 2008-12-30 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural comparison of crystal and solution states of the 138 kDa complex of methylamine dehydrogenase and amicyanin from Paracoccus versutus. Biochemistry, 47, 2008
|
|
1LM1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1lm1 by Molmil](/molmil-images/mine/1lm1) | Structural studies on the synchronization of catalytic centers in glutamate synthase: native enzyme | 分子名称: | ACETATE ION, FE3-S4 CLUSTER, FLAVIN MONONUCLEOTIDE, ... | 著者 | van Den Heuvel, R.H, Ferrari, D, Bossi, R.T, Ravasio, S, Curti, B, Vanoni, M.A, Florencio, F.J, Mattevi, A. | 登録日 | 2002-04-30 | 公開日 | 2002-07-31 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural studies on the synchronization of catalytic centers in glutamate synthase J.BIOL.CHEM., 277, 2002
|
|
1LLW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1llw by Molmil](/molmil-images/mine/1llw) | Structural studies on the synchronization of catalytic centers in glutamate synthase: complex with 2-oxoglutarate | 分子名称: | 2-OXOGLUTARIC ACID, FE3-S4 CLUSTER, FLAVIN MONONUCLEOTIDE, ... | 著者 | van den Heuvel, R.H, Ferrari, D, Bossi, R.T, Ravasio, S, Curti, B, Vanoni, M.A, Florencio, F.J, Mattevi, A. | 登録日 | 2002-04-30 | 公開日 | 2002-07-31 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural studies on the synchronization of catalytic centers in glutamate synthase J.BIOL.CHEM., 277, 2002
|
|
1LLZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1llz by Molmil](/molmil-images/mine/1llz) | Structural studies on the synchronization of catalytic centers in glutamate synthase: reduced enzyme | 分子名称: | FE3-S4 CLUSTER, FLAVIN MONONUCLEOTIDE, Ferredoxin-dependent glutamate synthase | 著者 | van den Heuvel, R.H, Ferrari, D, Bossi, R.T, Ravasio, S, Curti, B, Vanoni, M.A, Florencio, F.J, Mattevi, A. | 登録日 | 2002-04-30 | 公開日 | 2002-07-31 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural studies on the synchronization of catalytic centers in glutamate synthase J.BIOL.CHEM., 277, 2002
|
|
2UZX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2uzx by Molmil](/molmil-images/mine/2uzx) | Structure of the human receptor tyrosine kinase Met in complex with the Listeria monocytogenes invasion protein InlB: Crystal form I | 分子名称: | HEPATOCYTE GROWTH FACTOR RECEPTOR, INTERNALIN B | 著者 | Niemann, H.H, Jager, V, Butler, P.J.G, Van Den Heuvel, J, Schmidt, S, Ferraris, D, Gherardi, E, Heinz, D.W. | 登録日 | 2007-05-02 | 公開日 | 2007-08-07 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure of the Human Receptor Tyrosine Kinase met in Complex with the Listeria Invasion Protein Inlb Cell(Cambridge,Mass.), 130, 2007
|
|
2UZY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2uzy by Molmil](/molmil-images/mine/2uzy) | Structure of the human receptor tyrosine kinase Met in complex with the Listeria monocytogenes invasion protein inlb: low resolution, Crystal form II | 分子名称: | HEPATOCYTE GROWTH FACTOR RECEPTOR, INTERNALIN B | 著者 | Niemann, H.H, Jager, V, Butler, P.J.G, van den Heuvel, J, Schmidt, S, Ferraris, D, Gherardi, E, Heinz, D.W. | 登録日 | 2007-05-02 | 公開日 | 2007-08-07 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (4 Å) | 主引用文献 | Structure of the Human Receptor Tyrosine Kinase met in Complex with the Listeria Invasion Protein Inlb Cell(Cambridge,Mass.), 130, 2007
|
|
6G0W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6g0w by Molmil](/molmil-images/mine/6g0w) | Human PARP14 (ARTD8), catalytic fragment in complex with inhibitor MCD72 | 分子名称: | 4-[3-[4-(4-fluorophenyl)piperidin-1-yl]carbonylphenoxy]benzamide, Poly [ADP-ribose] polymerase 14 | 著者 | Karlberg, T, Thorsell, A.G, Holechek, J, Lease, R, Ferraris, D, Schuler, H. | 登録日 | 2018-03-20 | 公開日 | 2018-05-23 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | 主引用文献 | Design, synthesis and evaluation of potent and selective inhibitors of mono-(ADP-ribosyl)transferases PARP10 and PARP14. Bioorg. Med. Chem. Lett., 28, 2018
|
|
2H47
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2h47 by Molmil](/molmil-images/mine/2h47) | Crystal Structure of an Electron Transfer Complex Between Aromatic Amine Dephydrogenase and Azurin from Alcaligenes Faecalis (Form 1) | 分子名称: | Aromatic Amine Dehydrogenase, Azurin, COPPER (II) ION | 著者 | Sukumar, N, Chen, Z, Leys, D, Scrutton, N.S, Ferrati, D, Merli, A, Rossi, G.L, Bellamy, H.D, Chistoserdov, A, Davidson, V.L, Mathews, F.S. | 登録日 | 2006-05-23 | 公開日 | 2006-11-21 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal Structure of an Electron Transfer Complex between Aromatic Amine Dehydrogenase and Azurin from Alcaligenes faecalis. Biochemistry, 45, 2006
|
|
2H3X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2h3x by Molmil](/molmil-images/mine/2h3x) | Crystal Structure of an Electron Transfer Complex Between Aromatic Amine Dehydrogenase and Azurin from Alcaligenes Faecalis (Form 3) | 分子名称: | Aromatic Amine Dehydrogenase, Azurin, COPPER (II) ION | 著者 | Sukumar, N, Chen, Z, Leys, D, Scrutton, N.S, Ferrati, D, Merli, A, Rossi, G.L, Bellamy, H.D, Chistoserdov, A, Davidson, V.L, Mathews, F.S. | 登録日 | 2006-05-23 | 公開日 | 2006-11-21 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal Structure of an Electron Transfer Complex between Aromatic Amine Dehydrogenase and Azurin from Alcaligenes faecalis. Biochemistry, 45, 2006
|
|
2IAA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2iaa by Molmil](/molmil-images/mine/2iaa) | Crystal Structure of an Electron Transfer Complex Between Aromatic Amine Dephydrogenase and Azurin from Alcaligenes Faecalis (Form 2) | 分子名称: | Aromatic Amine Dehydrogenase, Azurin, COPPER (II) ION | 著者 | Sukumar, N, Chen, Z, Leys, D, Scrutton, N.S, Ferrati, D, Merli, A, Rossi, G.L, Bellamy, H.D, Chistoserdov, A, Davidson, V.L, Mathews, F.S. | 登録日 | 2006-09-07 | 公開日 | 2006-11-21 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystal Structure of an Electron Transfer Complex between Aromatic Amine Dehydrogenase and Azurin from Alcaligenes faecalis. Biochemistry, 45, 2006
|
|
5ELY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ely by Molmil](/molmil-images/mine/5ely) | X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with a hydroxamate inhibitor JHU242 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[(2~{R})-2-carboxy-5-(oxidanylamino)-5-oxidanylidene-pentyl]benzoic acid, ... | 著者 | Barinka, C, Novakova, Z, Pavlicek, J. | 登録日 | 2015-11-05 | 公開日 | 2016-04-27 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | 主引用文献 | Unprecedented Binding Mode of Hydroxamate-Based Inhibitors of Glutamate Carboxypeptidase II: Structural Characterization and Biological Activity. J.Med.Chem., 59, 2016
|
|
8TV7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8tv7 by Molmil](/molmil-images/mine/8tv7) | SARS-CoV-2 Mac1 in complex with MDOLL-0229 | 分子名称: | (1R,2R)-2-{[3-(methoxycarbonyl)-4,5,6,7,8,9-hexahydrocycloocta[b]thiophen-2-yl]carbamoyl}cyclohexane-1-carboxylic acid, GLYCEROL, Papain-like protease nsp3 | 著者 | Wazir, S, Maksimainen, M, Lehtio, L. | 登録日 | 2023-08-17 | 公開日 | 2024-04-24 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Discovery of 2-Amide-3-methylester Thiophenes that Target SARS-CoV-2 Mac1 and Repress Coronavirus Replication, Validating Mac1 as an Antiviral Target. J.Med.Chem., 67, 2024
|
|
8TV6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8tv6 by Molmil](/molmil-images/mine/8tv6) | SARS-CoV-2 Mac1 in complex with MDOLL-0169 | 分子名称: | (1R,6R)-6-{[3-(methoxycarbonyl)-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophen-2-yl]carbamoyl}cyclohex-3-ene-1-carboxylic acid, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | 著者 | Wazir, S, Maksimainen, M, Lehtio, L. | 登録日 | 2023-08-17 | 公開日 | 2024-04-17 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | Discovery of 2-Amide-3-methylester Thiophenes that Target SARS-CoV-2 Mac1 and Repress Coronavirus Replication, Validating Mac1 as an Antiviral Target. J.Med.Chem., 67, 2024
|
|
5NQE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5nqe by Molmil](/molmil-images/mine/5nqe) | Human PARP14 (ARTD8), catalytic fragment in complex with an N-aryl piperazine inhibitor | 分子名称: | 3-[[4-[4-(4-fluorophenyl)piperazin-1-yl]-4-oxidanylidene-butanoyl]amino]benzamide, Poly [ADP-ribose] polymerase 14 | 著者 | Karlberg, T, Thorsell, A.G, Schuler, H. | 登録日 | 2017-04-20 | 公開日 | 2017-05-24 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | 主引用文献 | Design and synthesis of potent inhibitors of the mono(ADP-ribosyl)transferase, PARP14. Bioorg. Med. Chem. Lett., 27, 2017
|
|
5D29
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5d29 by Molmil](/molmil-images/mine/5d29) | X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with a hydroxamate inhibitor JHU241 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[(2~{S})-2-carboxy-5-(oxidanylamino)-5-oxidanylidene-pentyl]benzoic acid, ... | 著者 | Barinka, C, Novakova, Z, Pavlicek, J. | 登録日 | 2015-08-05 | 公開日 | 2016-04-27 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Unprecedented Binding Mode of Hydroxamate-Based Inhibitors of Glutamate Carboxypeptidase II: Structural Characterization and Biological Activity. J.Med.Chem., 59, 2016
|
|