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4V9D
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BU of 4v9d by Molmil
Structures of the bacterial ribosome in classical and hybrid states of tRNA binding
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Dunkle, J.A, Wang, L, Feldman, M.B, Pulk, A, Chen, V.B, Kapral, G.J, Noeske, J, Richardson, J.S, Blanchard, S.C, Cate, J.H.D.
登録日2012-07-31
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structures of the bacterial ribosome in classical and hybrid states of tRNA binding.
Science, 332, 2011
6UY5
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BU of 6uy5 by Molmil
E. coli cysteine desulfurase SufS with a spontaneously rotated beta-hairpin
分子名称: Cysteine desulfurase, PYRIDOXAL-5'-PHOSPHATE
著者Dunkle, J.A, Frantom, P.A.
登録日2019-11-11
公開日2020-03-25
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.501 Å)
主引用文献Structural evidence for a latch mechanism regulating access to the active site of SufS-family cysteine desulfurases
Acta Crystallogr.,Sect.D, 76, 2020
4V7S
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BU of 4v7s by Molmil
Crystal structure of the E. coli ribosome bound to telithromycin.
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Dunkle, J.A, Xiong, L, Mankin, A.S, Cate, J.H.D.
登録日2010-08-05
公開日2014-07-09
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (3.2547 Å)
主引用文献Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action.
Proc.Natl.Acad.Sci.USA, 107, 2010
4V7T
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BU of 4v7t by Molmil
Crystal structure of the E. coli ribosome bound to chloramphenicol.
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Dunkle, J.A, Xiong, L, Mankin, A.S, Cate, J.H.D.
登録日2010-08-14
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.1942 Å)
主引用文献Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action.
Proc.Natl.Acad.Sci.USA, 107, 2010
4V7U
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BU of 4v7u by Molmil
Crystal structure of the E. coli ribosome bound to erythromycin.
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Dunkle, J.A, Xiong, L, Mankin, A.S, Cate, J.H.D.
登録日2010-08-15
公開日2014-07-09
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action.
Proc.Natl.Acad.Sci.USA, 107, 2010
4OX9
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BU of 4ox9 by Molmil
Crystal structure of the aminoglycoside resistance methyltransferase NpmA bound to the 30S ribosomal subunit
分子名称: 16S rRNA, 16S rRNA (adenine(1408)-N(1))-methyltransferase, 30S ribosomal protein S10, ...
著者Dunkle, J.A, Conn, G.L, Dunham, C.M.
登録日2014-02-04
公開日2014-04-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.8035 Å)
主引用文献Molecular recognition and modification of the 30S ribosome by the aminoglycoside-resistance methyltransferase NpmA.
Proc.Natl.Acad.Sci.USA, 111, 2014
4V7V
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BU of 4v7v by Molmil
Crystal structure of the E. coli ribosome bound to clindamycin.
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Dunkle, J.A, Xiong, L, Mankin, A.S, Cate, J.H.D.
登録日2010-08-16
公開日2014-07-09
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (3.2891 Å)
主引用文献Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action.
Proc.Natl.Acad.Sci.USA, 107, 2010
6MRH
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BU of 6mrh by Molmil
E. coli cysteine desulfurase SufS E96A with a cysteine persulfide intermediate
分子名称: Cysteine desulfurase, PYRIDOXAL-5'-PHOSPHATE
著者Dunkle, J.A, Frantom, P.A.
登録日2018-10-12
公開日2019-01-09
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Structural Evidence for Dimer-Interface-Driven Regulation of the Type II Cysteine Desulfurase, SufS.
Biochemistry, 58, 2019
6MRE
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BU of 6mre by Molmil
E. coli cysteine desulfurase SufS R92A with a cysteine persulfide intermediate
分子名称: Cysteine desulfurase, PYRIDOXAL-5'-PHOSPHATE
著者Dunkle, J.A, Frantom, P.A.
登録日2018-10-12
公開日2019-01-09
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Evidence for Dimer-Interface-Driven Regulation of the Type II Cysteine Desulfurase, SufS.
Biochemistry, 58, 2019
6MR6
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BU of 6mr6 by Molmil
E. coli cysteine desulfurase SufS H55A with a cysteine persulfide intermediate
分子名称: Cysteine desulfurase, PYRIDOXAL-5'-PHOSPHATE
著者Dunkle, J.A, Frantom, P.A.
登録日2018-10-11
公開日2019-01-09
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.019 Å)
主引用文献Structural Evidence for Dimer-Interface-Driven Regulation of the Type II Cysteine Desulfurase, SufS.
Biochemistry, 58, 2019
6MR2
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BU of 6mr2 by Molmil
E. coli cysteine desulfurase SufS with a cysteine persulfide intermediate
分子名称: Cysteine desulfurase, PYRIDOXAL-5'-PHOSPHATE
著者Dunkle, J.A, Frantom, P.A.
登録日2018-10-11
公開日2019-01-09
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.404 Å)
主引用文献Structural Evidence for Dimer-Interface-Driven Regulation of the Type II Cysteine Desulfurase, SufS.
Biochemistry, 58, 2019
6MRI
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BU of 6mri by Molmil
E. coli cysteine desulfurase SufS E250A with a cysteine persulfide intermediate
分子名称: Cysteine desulfurase, PYRIDOXAL-5'-PHOSPHATE
著者Dunkle, J.A, Frantom, P.A.
登録日2018-10-12
公開日2019-01-09
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Structural Evidence for Dimer-Interface-Driven Regulation of the Type II Cysteine Desulfurase, SufS.
Biochemistry, 58, 2019
9D2D
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BU of 9d2d by Molmil
E. coli cysteine desulfurase SufS R359A
分子名称: CHLORIDE ION, Cysteine desulfurase
著者Dunkle, J.A, Frantom, P.A.
登録日2024-08-08
公開日2024-10-23
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献To be published
To Be Published
8VBS
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BU of 8vbs by Molmil
E. coli cysteine desulfurase SufS bound to SufE C51A
分子名称: Cysteine desulfurase, Cysteine desulfuration protein SufE
著者Dunkle, J.A, Frantom, P.A, Gilbert, N.C.
登録日2023-12-12
公開日2024-10-16
実験手法X-RAY DIFFRACTION (3.31 Å)
主引用文献E. coli cysteine desulfurase SufS bound to SufE C51A
To Be Published
7RRN
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BU of 7rrn by Molmil
E. coli cysteine desulfurase SufS R56A
分子名称: CHLORIDE ION, Cysteine desulfurase, PYRIDOXAL-5'-PHOSPHATE
著者Dunkle, J.A, Gogar, R, Frantom, P.A.
登録日2021-08-10
公開日2023-01-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Contributions of the active site floor in cysteine desulfurase activity
To be published
7RW3
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BU of 7rw3 by Molmil
E. coli cysteine desulfurase SufS N99D
分子名称: Cysteine desulfurase, PYRIDOXAL-5'-PHOSPHATE
著者Dunkle, J.A, Gogar, R, Frantom, P.A.
登録日2021-08-19
公開日2023-01-25
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The beta-latch structural element of the SufS cysteine desulfurase mediates active site accessibility and SufE transpersulfurase positioning.
J.Biol.Chem., 299, 2023
7RUJ
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BU of 7ruj by Molmil
E. coli cysteine desulfurase SufS N99A
分子名称: CHLORIDE ION, Cysteine desulfurase, PYRIDOXAL-5'-PHOSPHATE
著者Dunkle, J.A, Gogar, R, Frantom, P.A.
登録日2021-08-17
公開日2023-01-25
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The beta-latch structural element of the SufS cysteine desulfurase mediates active site accessibility and SufE transpersulfurase positioning.
J.Biol.Chem., 299, 2023
6O12
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BU of 6o12 by Molmil
E. coli cysteine desulfurase SufS H123A
分子名称: CHLORIDE ION, Cysteine desulfurase, PYRIDOXAL-5'-PHOSPHATE
著者Dunkle, J.A, Frantom, P.A.
登録日2019-02-17
公開日2019-06-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Direct observation of intermediates in the SufS cysteine desulfurase reaction reveals functional roles of conserved active-site residues.
J.Biol.Chem., 294, 2019
6O13
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BU of 6o13 by Molmil
E. coli cysteine desulfurase SufS H123A with a Cys-ketimine intermediate
分子名称: CHLORIDE ION, Cys-ketimine, Cysteine desulfurase
著者Dunkle, J.A, Frantom, P.A.
登録日2019-02-17
公開日2019-07-03
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.203 Å)
主引用文献Direct observation of intermediates in the SufS cysteine desulfurase reaction reveals functional roles of conserved active-site residues.
J.Biol.Chem., 294, 2019
6O11
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BU of 6o11 by Molmil
E. coli cysteine desulfurase SufS C364A with a Cys-aldimine intermediate
分子名称: CHLORIDE ION, Cysteine desulfurase, N-({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)-L-CYSTEINE
著者Dunkle, J.A, Frantom, P.A.
登録日2019-02-17
公開日2019-06-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Direct observation of intermediates in the SufS cysteine desulfurase reaction reveals functional roles of conserved active-site residues.
J.Biol.Chem., 294, 2019
6O10
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BU of 6o10 by Molmil
E. coli cysteine desulfurase SufS
分子名称: CHLORIDE ION, Cysteine desulfurase, PYRIDOXAL-5'-PHOSPHATE
著者Dunkle, J.A, Frantom, P.A.
登録日2019-02-17
公開日2019-06-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Direct observation of intermediates in the SufS cysteine desulfurase reaction reveals functional roles of conserved active-site residues.
J.Biol.Chem., 294, 2019
4V6E
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BU of 4v6e by Molmil
Crystal structure of the E. coli 70S ribosome in an intermediate state of ratcheting
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Zhang, W, Dunkle, J.A, Cate, J.H.D.
登録日2009-06-28
公開日2014-07-09
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.712 Å)
主引用文献Structures of the ribosome in intermediate States of ratcheting.
Science, 325, 2009
4W4G
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BU of 4w4g by Molmil
Postcleavage state of 70S bound to HigB toxin and AAA (lysine) codon
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Schureck, M.A, Maehigashi, T, Dunkle, J.A, Dunham, C.M.
登録日2014-08-14
公開日2015-10-21
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Defining the mRNA recognition signature of a bacterial toxin protein.
Proc.Natl.Acad.Sci.USA, 112, 2015
4V6D
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BU of 4v6d by Molmil
Crystal structure of the E. coli 70S ribosome in an intermediate state of ratcheting
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Zhang, W, Dunkle, J.A, Cate, J.H.D.
登録日2009-06-27
公開日2014-07-09
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3.814 Å)
主引用文献Structures of the ribosome in intermediate States of ratcheting.
Science, 325, 2009
4V8J
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BU of 4v8j by Molmil
Crystal structure of the bacterial ribosome ram mutation G347U.
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Fagan, C.E, Dunkle, J.A, Maehigashi, T, Dunham, C.M.
登録日2011-12-20
公開日2014-07-09
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献Reorganization of an intersubunit bridge induced by disparate 16S ribosomal ambiguity mutations mimics an EF-Tu-bound state.
Proc.Natl.Acad.Sci.USA, 110, 2013

 

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