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5KHU
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BU of 5khu by Molmil
Model of human Anaphase-promoting complex/Cyclosome (APC15 deletion mutant), in complex with the Mitotic checkpoint complex (APC/C-CDC20-MCC) based on cryo EM data at 4.8 Angstrom resolution
分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ...
著者Yamaguchi, M, VanderLinden, R, Dube, P, Stark, H, Schulman, B.
登録日2016-06-15
公開日2016-09-07
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献Cryo-EM of Mitotic Checkpoint Complex-Bound APC/C Reveals Reciprocal and Conformational Regulation of Ubiquitin Ligation.
Mol.Cell, 63, 2016
5KHR
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BU of 5khr by Molmil
Model of human Anaphase-promoting complex/Cyclosome complex (APC15 deletion mutant) in complex with the E2 UBE2C/UBCH10 poised for ubiquitin ligation to substrate (APC/C-CDC20-substrate-UBE2C)
分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ...
著者VanderLinden, R, Yamaguchi, M, Dube, P, Haselbach, D, Stark, H, Schulman, B.A.
登録日2016-06-15
公開日2016-08-24
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (6.1 Å)
主引用文献Cryo-EM of Mitotic Checkpoint Complex-Bound APC/C Reveals Reciprocal and Conformational Regulation of Ubiquitin Ligation.
Mol.Cell, 63, 2016
5L9U
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BU of 5l9u by Molmil
Model of human Anaphase-promoting complex/Cyclosome (APC/C-CDH1) with a cross linked Ubiquitin variant-substrate-UBE2C (UBCH10) complex representing key features of multiubiquitination
分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ...
著者Brown, N.G, VanderLinden, R, Dube, P, Haselbach, D, Peters, J.M, Stark, H, Schulman, B.A.
登録日2016-06-11
公開日2016-09-14
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (6.4 Å)
主引用文献Dual RING E3 Architectures Regulate Multiubiquitination and Ubiquitin Chain Elongation by APC/C.
Cell, 165, 2016
5L9T
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BU of 5l9t by Molmil
Model of human Anaphase-promoting complex/Cyclosome (APC/C-CDH1) with E2 UBE2S poised for polyubiquitination where UBE2S, APC2, and APC11 are modeled into low resolution density
分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ...
著者Brown, N.G, VanderLinden, R, Dube, P, Haselbach, D, Peters, J.M, Stark, H, Schulman, B.A.
登録日2016-06-11
公開日2016-10-26
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (6.4 Å)
主引用文献Dual RING E3 Architectures Regulate Multiubiquitination and Ubiquitin Chain Elongation by APC/C.
Cell, 165, 2016
4R2Y
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BU of 4r2y by Molmil
Crystal structure of APC11 RING domain
分子名称: Anaphase-promoting complex subunit 11, ZINC ION
著者Brown, N.G, Watson, E.R, Weissmann, F, Jarvis, M.A, Vanderlinden, R, Grace, C.R.R, Frye, J.J, Dube, P, Qiao, R, Petzold, G, Cho, S.E, Alsharif, O, Bao, J, Zheng, J, Nourse, A, Kurinov, I, Peters, J.M, Stark, H, Schulman, B.A.
登録日2014-08-13
公開日2014-10-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.755 Å)
主引用文献Mechanism of Polyubiquitination by Human Anaphase-Promoting Complex: RING Repurposing for Ubiquitin Chain Assembly.
Mol.Cell, 56, 2014
5JG6
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BU of 5jg6 by Molmil
APC11-Ubv shows role of noncovalent RING-Ubiquitin interactions in processive multiubiquitination and Ubiquitin chain elongation by APC/C
分子名称: Anaphase-promoting complex subunit 11, Polyubiquitin-B, ZINC ION
著者Brown, N.G, Zhang, W, Yu, S, Miller, D.J, Sidhu, S.S, Schulman, B.A.
登録日2016-04-19
公開日2016-06-15
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.0013 Å)
主引用文献Dual RING E3 Architectures Regulate Multiubiquitination and Ubiquitin Chain Elongation by APC/C.
Cell, 165, 2016
2MT5
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BU of 2mt5 by Molmil
Isolated Ring domain
分子名称: Anaphase-promoting complex subunit 11, ZINC ION
著者Brown, N.G, Watson, E.R, Weissman, F, Royappa, G, Schulman, B, Jarvis, M, Vanderlinden, R, Frye, J.J, Qiao, R, Petzold, G, Peters, J, Stark, H.
登録日2014-08-13
公開日2014-10-29
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Mechanism of Polyubiquitination by Human Anaphase-Promoting Complex: RING Repurposing for Ubiquitin Chain Assembly.
Mol.Cell, 56, 2014
6XFN
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BU of 6xfn by Molmil
Crystal structure of the SARS-CoV-2 (COVID-19) main protease in complex with UAW243
分子名称: 3C-like proteinase, GLYCEROL, UAW243
著者Sacco, M, Ma, C, Wang, J, Chen, Y.
登録日2020-06-15
公開日2020-06-24
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure and inhibition of the SARS-CoV-2 main protease reveal strategy for developing dual inhibitors against M pro and cathepsin L.
Sci Adv, 6, 2020
6XBI
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BU of 6xbi by Molmil
Crystal structure of the SARS-CoV-2 (COVID-19) main protease in complex with inhibitor UAW248
分子名称: 3C-like proteinase, DIMETHYL SULFOXIDE, GLYCEROL, ...
著者Sacco, M, Ma, C, Wang, J, Chen, Y.
登録日2020-06-06
公開日2020-06-17
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure and inhibition of the SARS-CoV-2 main protease reveal strategy for developing dual inhibitors against M pro and cathepsin L.
Sci Adv, 6, 2020
6XBH
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BU of 6xbh by Molmil
Crystal structure of the SARS-CoV-2 (COVID-19) main protease in complex with inhibitor UAW247
分子名称: 3C-like proteinase, GLYCEROL, SODIUM ION, ...
著者Sacco, M, Ma, C, Wang, J, Chen, Y.
登録日2020-06-06
公開日2020-06-17
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure and inhibition of the SARS-CoV-2 main protease reveal strategy for developing dual inhibitors against M pro and cathepsin L.
Sci Adv, 6, 2020
6XA4
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BU of 6xa4 by Molmil
Crystal structure of the SARS-CoV-2 (COVID-19) main protease in complex with UAW241
分子名称: 3C-like proteinase, GLYCEROL, inhibitor UAW241
著者Sacco, M, Ma, C, Wang, J, Chen, Y.
登録日2020-06-03
公開日2020-06-17
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structure and inhibition of the SARS-CoV-2 main protease reveal strategy for developing dual inhibitors against M pro and cathepsin L.
Sci Adv, 6, 2020
6XBG
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BU of 6xbg by Molmil
Crystal structure of the SARS-CoV-2 (COVID-19) main protease in complex with inhibitor UAW246
分子名称: 3C-like proteinase, GLYCEROL, SODIUM ION, ...
著者Sacco, M, Ma, C, Wang, J, Chen, Y.
登録日2020-06-05
公開日2020-06-17
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structure and inhibition of the SARS-CoV-2 main protease reveal strategy for developing dual inhibitors against M pro and cathepsin L.
Sci Adv, 6, 2020
3EQX
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BU of 3eqx by Molmil
CRYSTAL STRUCTURE OF A FIC FAMILY PROTEIN (SO_4266) FROM SHEWANELLA ONEIDENSIS AT 1.6 A RESOLUTION
分子名称: FIC DOMAIN CONTAINING TRANSCRIPTIONAL REGULATOR, TRIETHYLENE GLYCOL
著者Joint Center for Structural Genomics (JCSG)
登録日2008-10-01
公開日2008-10-14
最終更新日2023-02-01
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure of the Fic (Filamentation induced by cAMP) family protein SO4266 (gi|24375750) from Shewanella oneidensis MR-1 at 1.6 A resolution.
Proteins, 75, 2009
3F1Z
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BU of 3f1z by Molmil
Crystal structure of putative nucleic acid-binding lipoprotein (YP_001337197.1) from Klebsiella pneumoniae subsp. pneumoniae MGH 78578 at 2.46 A resolution
分子名称: DI(HYDROXYETHYL)ETHER, putative nucleic acid-binding lipoprotein
著者Joint Center for Structural Genomics (JCSG)
登録日2008-10-28
公開日2008-11-18
最終更新日2023-02-01
実験手法X-RAY DIFFRACTION (2.46 Å)
主引用文献The structure of KPN03535 (gi|152972051), a novel putative lipoprotein from Klebsiella pneumoniae, reveals an OB-fold.
Acta Crystallogr.,Sect.F, 66, 2010
2IAY
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BU of 2iay by Molmil
Crystal structure of a duf1831 family protein (lp2179) from lactobacillus plantarum at 1.20 A resolution
分子名称: CHLORIDE ION, GLYCEROL, Hypothetical protein
著者Joint Center for Structural Genomics (JCSG)
登録日2006-09-08
公開日2006-10-10
最終更新日2023-01-25
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Structure of LP2179, the first representative of Pfam family PF08866, suggests a new fold with a role in amino-acid metabolism.
Acta Crystallogr.,Sect.F, 66, 2010
2ICH
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BU of 2ich by Molmil
CRYSTAL STRUCTURE OF A PUTATIVE ATTH (NE1406) FROM NITROSOMONAS EUROPAEA AT 2.00 A RESOLUTION
分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, GLYCEROL, Putative AttH, ...
著者Joint Center for Structural Genomics (JCSG)
登録日2006-09-12
公開日2006-10-03
最終更新日2023-01-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of the first representative of Pfam family PF09410 (DUF2006) reveals a structural signature of the calycin superfamily that suggests a role in lipid metabolism.
Acta Crystallogr.,Sect.F, 66, 2010
1J6U
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BU of 1j6u by Molmil
Crystal structure of UDP-N-acetylmuramate-alanine ligase MurC (TM0231) from Thermotoga maritima at 2.3 A resolution
分子名称: UDP-N-acetylmuramate-alanine ligase MurC
著者Joint Center for Structural Genomics (JCSG)
登録日2002-08-29
公開日2002-11-06
最終更新日2023-01-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of an Udp-n-acetylmuramate-alanine ligase MurC (TM0231) from Thermotoga maritima at 2.3 A resolution.
Proteins, 55, 2004
3H0N
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BU of 3h0n by Molmil
Crystal structure of a duf1470 family protein (jann_2411) from jannaschia sp. ccs1 at 1.45 A resolution
分子名称: ACETATE ION, GLYCEROL, NICKEL (II) ION, ...
著者Joint Center for Structural Genomics (JCSG)
登録日2009-04-09
公開日2009-04-21
最終更新日2023-02-01
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献The structure of Jann_2411 (DUF1470) from Jannaschia sp. at 1.45  resolution reveals a new fold (the ABATE domain) and suggests its possible role as a transcription regulator.
Acta Crystallogr.,Sect.F, 66, 2010
3L5O
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BU of 3l5o by Molmil
Crystal structure of protein with unknown function from DUF364 family (ZP_00559375.1) from Desulfitobacterium hafniense DCB-2 at 2.01 A resolution
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, IMIDAZOLE, ...
著者Joint Center for Structural Genomics, Joint Center for Structural Genomics (JCSG)
登録日2009-12-22
公開日2010-02-02
最終更新日2023-02-01
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Structure of the first representative of Pfam family PF04016 (DUF364) reveals enolase and Rossmann-like folds that combine to form a unique active site with a possible role in heavy-metal chelation.
Acta Crystallogr.,Sect.F, 66, 2010
3BYQ
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BU of 3byq by Molmil
Crystal structure of a duf1185 family protein (bb2672) from bordetella bronchiseptica rb50 at 1.70 A resolution
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, TETRAETHYLENE GLYCOL, ...
著者Joint Center for Structural Genomics (JCSG)
登録日2008-01-16
公開日2008-01-29
最終更新日2023-02-01
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structures of the first representatives of Pfam family PF06684 (DUF1185) reveal a novel variant of the Bacillus chorismate mutase fold and suggest a role in amino-acid metabolism.
Acta Crystallogr.,Sect.F, 66, 2010
3BY7
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BU of 3by7 by Molmil
CRYSTAL STRUCTURE OF A PROTEIN STRUCTURALLY SIMILAR TO SM/LSM-LIKE RNA-BINDING PROTEINS (JCVI_PEP_1096686650277) FROM UNCULTURED MARINE ORGANISM AT 2.60 A RESOLUTION
分子名称: uncharacterized protein
著者Joint Center for Structural Genomics (JCSG)
登録日2008-01-15
公開日2008-01-29
最終更新日2023-02-01
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of a novel Sm-like protein of putative cyanophage origin at 2.60 A resolution.
Proteins, 75, 2009
3K5J
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BU of 3k5j by Molmil
Crystal structure of Putative SUFU (suppressor of fused protein) homolog (YP_208451.1) from Neisseria gonorrhoeae FA 1090 at 1.40 A resolution
分子名称: GLYCEROL, SULFATE ION, Suppressor of fused family protein
著者Joint Center for Structural Genomics (JCSG)
登録日2009-10-07
公開日2010-01-26
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献The crystal structure of a bacterial Sufu-like protein defines a novel group of bacterial proteins that are similar to the N-terminal domain of human Sufu.
Protein Sci., 19, 2010
3DEE
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BU of 3dee by Molmil
CRYSTAL STRUCTURE OF A PUTATIVE REGULATORY PROTEIN INVOLVED IN TRANSCRIPTION (NGO1945) FROM NEISSERIA GONORRHOEAE FA 1090 AT 2.25 A RESOLUTION
分子名称: CHLORIDE ION, IMIDAZOLE, Putative regulatory protein
著者Joint Center for Structural Genomics (JCSG)
登録日2008-06-09
公開日2008-08-05
最終更新日2023-02-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The structure of the first representative of Pfam family PF09836 reveals a two-domain organization and suggests involvement in transcriptional regulation.
Acta Crystallogr.,Sect.F, 66, 2010
3KK7
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BU of 3kk7 by Molmil
Crystal structure of Putative cell invasion protein with MAC/Perforin domain (NP_812351.1) from BACTERIODES THETAIOTAOMICRON VPI-5482 at 2.46 A resolution
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, CHLORIDE ION, ...
著者Joint Center for Structural Genomics (JCSG)
登録日2009-11-04
公開日2009-11-24
最終更新日2023-02-01
実験手法X-RAY DIFFRACTION (2.46 Å)
主引用文献Structure of a membrane-attack complex/perforin (MACPF) family protein from the human gut symbiont Bacteroides thetaiotaomicron.
Acta Crystallogr.,Sect.F, 66, 2010
2OOC
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BU of 2ooc by Molmil
Crystal structure of Histidine Phosphotransferase ShpA (NP_419930.1) from Caulobacter crescentus at 1.52 A resolution
分子名称: GLYCEROL, Histidine phosphotransferase, TETRAETHYLENE GLYCOL
著者Joint Center for Structural Genomics (JCSG)
登録日2007-01-25
公開日2007-02-06
最終更新日2023-01-25
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献Crystal structure of histidine phosphotransfer protein ShpA, an essential regulator of stalk biogenesis in Caulobacter crescentus.
J.Mol.Biol., 390, 2009

 

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