3SPW
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![BU of 3spw by Molmil](/molmil-images/mine/3spw) | Structure of Osh4p/Kes1p in complex with phosphatidylinositol 4-phosphate | 分子名称: | (2R)-1-(heptadecanoyloxy)-3-{[(R)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate, Protein KES1 | 著者 | Delfosse, V, de Saint-Jean, M, Douguet, D, Antonny, B, Drin, G, Bourguet, W. | 登録日 | 2011-07-04 | 公開日 | 2011-11-23 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Osh4p exchanges sterols for phosphatidylinositol 4-phosphate between lipid bilayers. J.Cell Biol., 195, 2011
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2Y8T
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![BU of 2y8t by Molmil](/molmil-images/mine/2y8t) | Co-structure of AMA1 with a surface exposed region of RON2 from Toxoplasma gondii | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, APICAL MEMBRANE ANTIGEN, PUTATIVE, ... | 著者 | Tonkin, M.L, Roques, M, Lamarque, M.H, Pugniere, M, Douguet, D, Crawford, J, Lebrun, M, Boulanger, M.J. | 登録日 | 2011-02-10 | 公開日 | 2011-08-03 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Host Cell Invasion by Apicomplexan Parasites: Insights from the Co-Structure of Ama1 with a Ron2 Peptide Science, 333, 2011
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2Y8S
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![BU of 2y8s by Molmil](/molmil-images/mine/2y8s) | Co-structure of an AMA1 mutant (Y230A) with a surface exposed region of RON2 from Toxoplasma gondii | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, APICAL MEMBRANE ANTIGEN, PUTATIVE, ... | 著者 | Tonkin, M.L, Roques, M, Lamarque, M.H, Pugniere, M, Douguet, D, Crawford, J, Lebrun, M, Boulanger, M.J. | 登録日 | 2011-02-10 | 公開日 | 2011-08-03 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Host Cell Invasion by Apicomplexan Parasites: Insights from the Co-Structure of Ama1 with a Ron2 Peptide Science, 333, 2011
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2Y8R
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![BU of 2y8r by Molmil](/molmil-images/mine/2y8r) | Crystal structure of apo AMA1 mutant (Tyr230Ala) from Toxoplasma gondii | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, APICAL MEMBRANE ANTIGEN, PUTATIVE | 著者 | Tonkin, M.L, Roques, M, Lamarque, M.H, Pugniere, M, Douguet, D, Crawford, J, Lebrun, M, Boulanger, M.J. | 登録日 | 2011-02-10 | 公開日 | 2011-08-03 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Host Cell Invasion by Apicomplexan Parasites: Insights from the Co-Structure of Ama1 with a Ron2 Peptide Science, 333, 2011
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5DU1
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![BU of 5du1 by Molmil](/molmil-images/mine/5du1) | Crystal structure of Dendroaspis polylepis mambalgin-1 wild-type in P21 space group. | 分子名称: | Mambalgin-1 | 著者 | Stura, E.A, Tepshi, L, Mourier, G, Kessler, P, Servent, D. | 登録日 | 2015-09-18 | 公開日 | 2015-12-30 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Mambalgin-1 Pain-relieving Peptide, Stepwise Solid-phase Synthesis, Crystal Structure, and Functional Domain for Acid-sensing Ion Channel 1a Inhibition. J.Biol.Chem., 291, 2016
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5DO6
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![BU of 5do6 by Molmil](/molmil-images/mine/5do6) | Crystal structure of Dendroaspis polylepis venom mambalgin-1 T23A mutant | 分子名称: | 1,2-ETHANEDIOL, IODIDE ION, Mambalgin-1, ... | 著者 | Stura, E.A, Tepshi, L, Kessler, P, Gilles, M, Servent, D. | 登録日 | 2015-09-10 | 公開日 | 2015-12-30 | 最終更新日 | 2017-01-25 | 実験手法 | X-RAY DIFFRACTION (1.697 Å) | 主引用文献 | Mambalgin-1 Pain-relieving Peptide, Stepwise Solid-phase Synthesis, Crystal Structure, and Functional Domain for Acid-sensing Ion Channel 1a Inhibition. J.Biol.Chem., 291, 2016
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5DZ5
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![BU of 5dz5 by Molmil](/molmil-images/mine/5dz5) | Crystal structure of Dendroaspis polylepis mambalgin-1 wild-type in P41212 space group | 分子名称: | Mambalgin-1 | 著者 | Stura, E.A, Tepshi, L, Mourier, G, Kessler, P, Servent, D. | 登録日 | 2015-09-25 | 公開日 | 2015-12-30 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Mambalgin-1 Pain-relieving Peptide, Stepwise Solid-phase Synthesis, Crystal Structure, and Functional Domain for Acid-sensing Ion Channel 1a Inhibition. J.Biol.Chem., 291, 2016
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4J5B
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![BU of 4j5b by Molmil](/molmil-images/mine/4j5b) | Human Cyclophilin D Complexed with an Inhibitor | 分子名称: | 1-(4-aminobenzyl)-3-(2-{(2R)-2-[2-(methylsulfanyl)phenyl]pyrrolidin-1-yl}-2-oxoethyl)urea, Peptidyl-prolyl cis-trans isomerase F, mitochondrial | 著者 | Gelin, M, Colliandre, L, Bessin, Y, Guichou, J.F. | 登録日 | 2013-02-08 | 公開日 | 2014-02-19 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities. Nat Commun, 7, 2016
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4J5D
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![BU of 4j5d by Molmil](/molmil-images/mine/4j5d) | Human Cyclophilin D Complexed with an Inhibitor | 分子名称: | 1-(4-aminobenzyl)-3-{2-[(2R)-2-(2-bromophenyl)pyrrolidin-1-yl]-2-oxoethyl}urea, Peptidyl-prolyl cis-trans isomerase F, mitochondrial | 著者 | Gelin, M, Colliandre, L, Bessin, Y, Guichou, J.F. | 登録日 | 2013-02-08 | 公開日 | 2014-02-19 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.32 Å) | 主引用文献 | Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities. Nat Commun, 7, 2016
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4J58
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![BU of 4j58 by Molmil](/molmil-images/mine/4j58) | Human Cyclophilin D Complexed with an Inhibitor | 分子名称: | 1-(4-aminobenzyl)-3-[2-oxo-2-(pyrrolidin-1-yl)ethyl]urea, PHOSPHATE ION, Peptidyl-prolyl cis-trans isomerase F, ... | 著者 | Colliandre, L, Gelin, M, Bessin, Y, Guichou, J.F. | 登録日 | 2013-02-08 | 公開日 | 2014-02-19 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.28 Å) | 主引用文献 | Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities. Nat Commun, 7, 2016
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4J5C
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![BU of 4j5c by Molmil](/molmil-images/mine/4j5c) | Human Cyclophilin D Complexed with an Inhibitor | 分子名称: | 1-(4-aminobenzyl)-3-[(2S)-4-(methylsulfanyl)-1-{(2R)-2-[2-(methylsulfanyl)phenyl]pyrrolidin-1-yl}-1-oxobutan-2-yl]urea, Peptidyl-prolyl cis-trans isomerase F, mitochondrial | 著者 | Gelin, M, Colliandre, L, Bessin, Y, Guichou, J.F. | 登録日 | 2013-02-08 | 公開日 | 2014-02-19 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.03 Å) | 主引用文献 | Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities. Nat Commun, 7, 2016
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4J5E
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![BU of 4j5e by Molmil](/molmil-images/mine/4j5e) | Human Cyclophilin D Complexed with an Inhibitor | 分子名称: | 1-(4-aminobenzyl)-3-{2-[(2R)-2-(2-methoxyphenyl)pyrrolidin-1-yl]-2-oxoethyl}urea, Peptidyl-prolyl cis-trans isomerase F, mitochondrial | 著者 | Gelin, M, Colliandre, L, Bessin, Y, Guichou, J.F. | 登録日 | 2013-02-08 | 公開日 | 2014-02-19 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (0.99 Å) | 主引用文献 | Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities. Nat Commun, 7, 2016
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4J59
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![BU of 4j59 by Molmil](/molmil-images/mine/4j59) | Human Cyclophilin D Complexed with an Inhibitor | 分子名称: | 1-(4-aminobenzyl)-3-{2-[(2R)-2-(naphthalen-1-yl)pyrrolidin-1-yl]-2-oxoethyl}urea, Peptidyl-prolyl cis-trans isomerase F, mitochondrial | 著者 | Gelin, M, Colliandre, L, Bessin, Y, Guichou, J.F. | 登録日 | 2013-02-08 | 公開日 | 2014-02-19 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities. Nat Commun, 7, 2016
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4J5A
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![BU of 4j5a by Molmil](/molmil-images/mine/4j5a) | Human Cyclophilin D Complexed with an Inhibitor | 分子名称: | 1-(4-aminobenzyl)-3-{2-[(2R)-2-(2,5-dimethoxyphenyl)pyrrolidin-1-yl]-2-oxoethyl}urea, DIMETHYL SULFOXIDE, Peptidyl-prolyl cis-trans isomerase F, ... | 著者 | Gelin, M, Colliandre, L, Bessin, Y, Guichou, J.F. | 登録日 | 2013-02-08 | 公開日 | 2014-02-19 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | 主引用文献 | Rationnal Design of small-molecule inhibitors of human Cyclophilins and HCV replication. to be published
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3R4G
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![BU of 3r4g by Molmil](/molmil-images/mine/3r4g) | Human Cyclophilin D Complexed with a Fragment | 分子名称: | 4-sulfamoylbenzoic acid, GLYCEROL, Peptidyl-prolyl cis-trans isomerase F, ... | 著者 | Colliandre, L, Ahmed-Belkacem, H, Bessin, Y, Pawlotsky, J.M, Guichou, J.F. | 登録日 | 2011-03-17 | 公開日 | 2012-03-21 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | 主引用文献 | Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities. Nat Commun, 7, 2016
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3R57
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![BU of 3r57 by Molmil](/molmil-images/mine/3r57) | Human Cyclophilin D Complexed with a Fragment | 分子名称: | GLYCEROL, N-(3-aminophenyl)acetamide, Peptidyl-prolyl cis-trans isomerase F, ... | 著者 | Colliandre, L, Ahmed-Belkacem, H, Bessin, Y, Pawlotsky, J.M, Guichou, J.F. | 登録日 | 2011-03-18 | 公開日 | 2012-03-21 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | 主引用文献 | Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities. Nat Commun, 7, 2016
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3RCF
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![BU of 3rcf by Molmil](/molmil-images/mine/3rcf) | Human cyclophilin D complexed with N-[(4-aminophenyl)sulfonyl]benzamide | 分子名称: | N-[(4-aminophenyl)sulfonyl]benzamide, Peptidyl-prolyl cis-trans isomerase F, mitochondrial | 著者 | Colliandre, L, Ahmed-Belkacem, H, Bessin, Y, Pawlotsky, J.M, Guichou, J.F. | 登録日 | 2011-03-31 | 公開日 | 2012-03-21 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | 主引用文献 | Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities. Nat Commun, 7, 2016
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3RCL
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![BU of 3rcl by Molmil](/molmil-images/mine/3rcl) | Human Cyclophilin D Complexed with a Fragment | 分子名称: | 3-(1,3-oxazol-5-yl)aniline, O-ACETALDEHYDYL-HEXAETHYLENE GLYCOL, Peptidyl-prolyl cis-trans isomerase F, ... | 著者 | Colliandre, L, Ahmed-Belkacem, H, Bessin, Y, Pawlotsky, J.M, Guichou, J.F. | 登録日 | 2011-03-31 | 公開日 | 2012-03-21 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities. Nat Commun, 7, 2016
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3R49
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![BU of 3r49 by Molmil](/molmil-images/mine/3r49) | Human cyclophilin D complexed with quinolin-8-amine | 分子名称: | Peptidyl-prolyl cis-trans isomerase F, mitochondrial, quinolin-8-amine | 著者 | Colliandre, L, Ahmed-Belkacem, H, Bessin, Y, Pawlotsky, J.M, Guichou, J.F. | 登録日 | 2011-03-17 | 公開日 | 2012-03-21 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities. Nat Commun, 7, 2016
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3RD9
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![BU of 3rd9 by Molmil](/molmil-images/mine/3rd9) | Human Cyclophilin D Complexed with a Fragment | 分子名称: | 3-(3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide, DI(HYDROXYETHYL)ETHER, Peptidyl-prolyl cis-trans isomerase F, ... | 著者 | Colliandre, L, Ahmed-Belkacem, H, Bessin, Y, Pawlotsky, J.M, Guichou, J.F. | 登録日 | 2011-04-01 | 公開日 | 2012-03-21 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities. Nat Commun, 7, 2016
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3R59
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![BU of 3r59 by Molmil](/molmil-images/mine/3r59) | Human Cyclophilin D Complexed with a Fragment | 分子名称: | 1-(3-aminophenyl)ethanone, Peptidyl-prolyl cis-trans isomerase F, mitochondrial | 著者 | Colliandre, L, Ahmed-Belkacem, H, Bessin, Y, Pawlotsky, J.M, Guichou, J.F. | 登録日 | 2011-03-18 | 公開日 | 2012-03-21 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities. Nat Commun, 7, 2016
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3RDA
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![BU of 3rda by Molmil](/molmil-images/mine/3rda) | Human Cyclophilin D Complexed with a Fragment | 分子名称: | 3-methyl-1,2-oxazol-5-amine, Peptidyl-prolyl cis-trans isomerase F, mitochondrial | 著者 | Colliandre, L, Ahmed-Belkacem, H, Bessin, Y, Pawlotsky, J.M, Guichou, J.F. | 登録日 | 2011-04-01 | 公開日 | 2012-03-21 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.07 Å) | 主引用文献 | Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities. Nat Commun, 7, 2016
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3RDB
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![BU of 3rdb by Molmil](/molmil-images/mine/3rdb) | Human Cyclophilin D Complexed with a Fragment | 分子名称: | 3-[5-(chloromethyl)-1,2,4-oxadiazol-3-yl]aniline, O-ACETALDEHYDYL-HEXAETHYLENE GLYCOL, Peptidyl-prolyl cis-trans isomerase F, ... | 著者 | Colliandre, L, Ahmed-Belkacem, H, Bessin, Y, Pawlotsky, J.M, Guichou, J.F. | 登録日 | 2011-04-01 | 公開日 | 2012-03-21 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities. Nat Commun, 7, 2016
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3R54
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![BU of 3r54 by Molmil](/molmil-images/mine/3r54) | Human Cyclophilin D Complexed with a Fragment | 分子名称: | Peptidyl-prolyl cis-trans isomerase F, mitochondrial, pyrrolidine-1-carbaldehyde | 著者 | Colliandre, L, Ahmed-Belkacem, H, Bessin, Y, Pawlotsky, J.M, Guichou, J.F. | 登録日 | 2011-03-18 | 公開日 | 2012-03-21 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities. Nat Commun, 7, 2016
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3RCK
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![BU of 3rck by Molmil](/molmil-images/mine/3rck) | Human Cyclophilin D Complexed with a Fragment | 分子名称: | Peptidyl-prolyl cis-trans isomerase F, mitochondrial, piperazine-1-carbaldehyde | 著者 | Colliandre, L, Ahmed-Belkacem, H, Bessin, Y, Pawlotsky, J.M, Guichou, J.F. | 登録日 | 2011-03-31 | 公開日 | 2012-03-21 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.26 Å) | 主引用文献 | Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities. Nat Commun, 7, 2016
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