4ZWO
 
 | | Crystal structure of organophosphate anhydrolase/prolidase mutant Y212F | | 分子名称: | GLYCEROL, GLYCOLIC ACID, MANGANESE (II) ION, ... | | 著者 | Daczkowski, C.M, Pegan, S.D, Harvey, S.P. | | 登録日 | 2015-05-19 | | 公開日 | 2015-10-14 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.141 Å) | | 主引用文献 | Engineering the Organophosphorus Acid Anhydrolase Enzyme for Increased Catalytic Efficiency and Broadened Stereospecificity on Russian VX.
Biochemistry, 54, 2015
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4ZWP
 | | Crystal structure of organophosphate anhydrolase/prolidase mutant Y212F | | 分子名称: | BARIUM ION, GLYCEROL, MANGANESE (II) ION, ... | | 著者 | Daczkowski, C.M, Pegan, S.D, Harvey, S.P. | | 登録日 | 2015-05-19 | | 公開日 | 2015-10-14 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.397 Å) | | 主引用文献 | Engineering the Organophosphorus Acid Anhydrolase Enzyme for Increased Catalytic Efficiency and Broadened Stereospecificity on Russian VX.
Biochemistry, 54, 2015
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4ZWU
 | | Crystal structure of organophosphate anhydrolase/prolidase mutant Y212F, V342L, I215Y | | 分子名称: | BARIUM ION, GLYCEROL, GLYCOLIC ACID, ... | | 著者 | Daczkowski, C.M, Pegan, S.D, Harvey, S.P. | | 登録日 | 2015-05-19 | | 公開日 | 2015-10-14 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Engineering the Organophosphorus Acid Anhydrolase Enzyme for Increased Catalytic Efficiency and Broadened Stereospecificity on Russian VX.
Biochemistry, 54, 2015
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5W8T
 | | Crystal structure of MERS-CoV papain-like protease in complex with the C-terminal domain of human ISG15 | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, ORF1ab, Ubiquitin-like protein ISG15, ... | | 著者 | Daczkowski, C.M, Goodwin, O.Y, Dzimianski, J.V, Farhat, J.J, Pegan, S.D. | | 登録日 | 2017-06-22 | | 公開日 | 2017-09-27 | | 最終更新日 | 2024-04-24 | | 実験手法 | X-RAY DIFFRACTION (2.758 Å) | | 主引用文献 | Structurally Guided Removal of DeISGylase Biochemical Activity from Papain-Like Protease Originating from Middle East Respiratory Syndrome Coronavirus.
J. Virol., 91, 2017
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5W8U
 | | Crystal structure of MERS-CoV papain-like protease in complex with the C-terminal domain of human ISG15 | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, ORF1ab, Ubiquitin-like protein ISG15, ... | | 著者 | Daczkowski, C.M, Goodwin, O.Y, Dzimianski, J.D, Pegan, S.D. | | 登録日 | 2017-06-22 | | 公開日 | 2017-09-27 | | 最終更新日 | 2024-04-24 | | 実験手法 | X-RAY DIFFRACTION (2.411 Å) | | 主引用文献 | Structurally Guided Removal of DeISGylase Biochemical Activity from Papain-Like Protease Originating from Middle East Respiratory Syndrome Coronavirus.
J. Virol., 91, 2017
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5TL6
 | | Crystal structure of SARS-CoV papain-like protease in complex with the C-terminal domain of human ISG15 | | 分子名称: | Replicase polyprotein 1ab, SULFATE ION, Ubiquitin-like protein ISG15, ... | | 著者 | Dzimianski, J.V, Daczkowski, C.M, Pegan, S.D. | | 登録日 | 2016-10-10 | | 公開日 | 2017-05-03 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.618 Å) | | 主引用文献 | Structural Insights into the Interaction of Coronavirus Papain-Like Proteases and Interferon-Stimulated Gene Product 15 from Different Species.
J. Mol. Biol., 429, 2017
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5TLA
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7MC9
 | | X-RAY STRUCTURE OF PEDV PAPAIN-LIKE PROTEASE 2 bound to UB-PA | | 分子名称: | 3C-like proteinase, Ubiquitin, ZINC ION, ... | | 著者 | Durie, I.A, Dzimianski, J.V, Daczkowski, C.M, Pegan, S.D. | | 登録日 | 2021-04-01 | | 公開日 | 2021-07-07 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.099 Å) | | 主引用文献 | Structural insights into the interaction of papain-like protease 2 from the alphacoronavirus porcine epidemic diarrhea virus and ubiquitin
Acta Cryst. D, 77, 2021
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6DWX
 | | Crystal structure of SeMet phased viral OTU domain protease from Qalyub virus | | 分子名称: | RNA-dependent RNA polymerase | | 著者 | Dzimianski, J.V, Beldon, B.S, Daczkowski, C.M, Goodwin, O.Y, Pegan, S.D. | | 登録日 | 2018-06-28 | | 公開日 | 2018-12-19 | | 最終更新日 | 2019-12-18 | | 実験手法 | X-RAY DIFFRACTION (2.395 Å) | | 主引用文献 | Probing the impact of nairovirus genomic diversity on viral ovarian tumor domain protease (vOTU) structure and deubiquitinase activity.
PLoS Pathog., 15, 2019
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6DX1
 | | Crystal structure of the viral OTU domain protease from Qalyub virus | | 分子名称: | RNA-dependent RNA polymerase | | 著者 | Dzimianski, J.V, Beldon, B.S, Daczkowski, C.M, Goodwin, O.Y, Pegan, S.D. | | 登録日 | 2018-06-28 | | 公開日 | 2018-12-19 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.652 Å) | | 主引用文献 | Probing the impact of nairovirus genomic diversity on viral ovarian tumor domain protease (vOTU) structure and deubiquitinase activity.
PLoS Pathog., 15, 2019
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6DX3
 | | Crystal structure of the viral OTU domain protease from Taggert virus | | 分子名称: | MAGNESIUM ION, RNA-dependent RNA polymerase | | 著者 | Dzimianski, J.V, Beldon, B.S, Daczkowski, C.M, Goodwin, O.Y, Pegan, S.D. | | 登録日 | 2018-06-28 | | 公開日 | 2018-12-19 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.052 Å) | | 主引用文献 | Probing the impact of nairovirus genomic diversity on viral ovarian tumor domain protease (vOTU) structure and deubiquitinase activity.
PLoS Pathog., 15, 2019
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6DX2
 | | Crystal structure of the viral OTU domain protease from Dera Ghazi Khan virus | | 分子名称: | RNA-dependent RNA polymerase | | 著者 | Beldon, B.S, Dzimianski, J.V, Daczkowski, C.M, Goodwin, O.Y, Pegan, S.D. | | 登録日 | 2018-06-28 | | 公開日 | 2018-12-19 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.614 Å) | | 主引用文献 | Probing the impact of nairovirus genomic diversity on viral ovarian tumor domain protease (vOTU) structure and deubiquitinase activity.
PLoS Pathog., 15, 2019
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6DX5
 | | Crystal structure of the viral OTU domain protease from Farallon virus | | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, RNA-dependent RNA polymerase | | 著者 | Beldon, B.S, Dzimianski, J.V, Daczkowski, C.M, Goodwin, O.Y, Pegan, S.D. | | 登録日 | 2018-06-28 | | 公開日 | 2018-12-19 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.224 Å) | | 主引用文献 | Probing the impact of nairovirus genomic diversity on viral ovarian tumor domain protease (vOTU) structure and deubiquitinase activity.
PLoS Pathog., 15, 2019
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6MDH
 | | X-ray crystal structure of ISG15 from Myotis davidii | | 分子名称: | Ubiquitin-like protein ISG15 | | 著者 | Goodwin, O.Y, Langley, C.A, Dzimianski, J.V, Daczkowski, C.M, Pegan, S.D. | | 登録日 | 2018-09-04 | | 公開日 | 2018-12-12 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | | 主引用文献 | Structure of interferon-stimulated gene product 15 (ISG15) from the bat species Myotis davidii and the impact of interdomain ISG15 interactions on viral protein engagement.
Acta Crystallogr D Struct Biol, 75, 2019
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5TL7
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5JZE
 | | Erve virus viral OTU domain protease in complex with mouse ISG15 | | 分子名称: | CITRATE ANION, RNA-dependent RNA polymerase, Ubiquitin-like protein ISG15, ... | | 著者 | Deaton, M.K, Dzimianski, J.V, Pegan, S.D. | | 登録日 | 2016-05-16 | | 公開日 | 2016-10-19 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | | 主引用文献 | Biochemical and Structural Insights into the Preference of Nairoviral DeISGylases for Interferon-Stimulated Gene Product 15 Originating from Certain Species.
J.Virol., 90, 2016
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6OMV
 | | CryoEM structure of the LbCas12a-crRNA-AcrVA4-DNA complex | | 分子名称: | AcrVA4, Cpf1, DNA (5'-D(*CP*GP*TP*CP*CP*TP*TP*TP*AP*GP*GP*A)-3'), ... | | 著者 | Chang, L, Li, Z, Zhang, H. | | 登録日 | 2019-04-19 | | 公開日 | 2019-06-12 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structural Basis for the Inhibition of CRISPR-Cas12a by Anti-CRISPR Proteins.
Cell Host Microbe, 25, 2019
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6NMA
 | | CryoEM structure of the LbCas12a-crRNA-AcrVA4 complex | | 分子名称: | AcrVA1, Cpf1, MAGNESIUM ION, ... | | 著者 | Chang, L, Li, Z, Zhang, H. | | 登録日 | 2019-01-10 | | 公開日 | 2019-06-12 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.38 Å) | | 主引用文献 | Structural Basis for the Inhibition of CRISPR-Cas12a by Anti-CRISPR Proteins.
Cell Host Microbe, 25, 2019
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6NM9
 | | CryoEM structure of the LbCas12a-crRNA-AcrVA4 dimer | | 分子名称: | AcrVA4, Cpf1, MAGNESIUM ION, ... | | 著者 | Chang, L, Li, Z, Zhang, H. | | 登録日 | 2019-01-10 | | 公開日 | 2019-06-12 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.38 Å) | | 主引用文献 | Structural Basis for the Inhibition of CRISPR-Cas12a by Anti-CRISPR Proteins.
Cell Host Microbe, 25, 2019
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6NME
 | | Structure of LbCas12a-crRNA | | 分子名称: | Cpf1, MAGNESIUM ION, crRNA | | 著者 | Chang, L, Li, Z, Zhang, H. | | 登録日 | 2019-01-10 | | 公開日 | 2019-06-12 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (5.67 Å) | | 主引用文献 | Structural Basis for the Inhibition of CRISPR-Cas12a by Anti-CRISPR Proteins.
Cell Host Microbe, 25, 2019
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6NMC
 | | CryoEM structure of the LbCas12a-crRNA-2xAcrVA1 complex | | 分子名称: | AcrVA1, Cpf1, MAGNESIUM ION, ... | | 著者 | Chang, L, Li, Z, Zhang, H. | | 登録日 | 2019-01-10 | | 公開日 | 2019-06-12 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (4.24 Å) | | 主引用文献 | Structural Basis for the Inhibition of CRISPR-Cas12a by Anti-CRISPR Proteins.
Cell Host Microbe, 25, 2019
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6NMD
 | | cryo-EM Structure of the LbCas12a-crRNA-AcrVA1 complex | | 分子名称: | AcrVA1, Cpf1, MAGNESIUM ION, ... | | 著者 | Chang, L, Li, Z, Zhang, H. | | 登録日 | 2019-01-10 | | 公開日 | 2019-06-12 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.49 Å) | | 主引用文献 | Structural Basis for the Inhibition of CRISPR-Cas12a by Anti-CRISPR Proteins.
Cell Host Microbe, 25, 2019
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7JYY
 | | Crystal Structure of SARS-CoV-2 Nsp16/10 Heterodimer in Complex with (m7GpppA)pUpUpApApA (Cap-0) and S-Adenosylmethionine (SAM). | | 分子名称: | 2'-O-methyltransferase, CHLORIDE ION, FORMIC ACID, ... | | 著者 | Minasov, G, Shuvalova, L, Rosas-Lemus, M, Kiryukhina, O, Brunzelle, J.S, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2020-09-01 | | 公開日 | 2020-09-16 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Mn 2+ coordinates Cap-0-RNA to align substrates for efficient 2'- O -methyl transfer by SARS-CoV-2 nsp16.
Sci.Signal., 14, 2021
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7L6R
 | | Crystal Structure of SARS-CoV-2 Nsp16/10 Heterodimer in Complex with (m7GpppA2m)pUpUpApApA (Cap-1), S-Adenosyl-L-homocysteine (SAH) and Manganese (Mn). | | 分子名称: | 2'-O-methyltransferase, CHLORIDE ION, MANGANESE (II) ION, ... | | 著者 | Minasov, G, Shuvalova, L, Rosas-Lemus, M, Kiryukhina, O, Brunzelle, J.S, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2020-12-23 | | 公開日 | 2021-01-06 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Mn 2+ coordinates Cap-0-RNA to align substrates for efficient 2'- O -methyl transfer by SARS-CoV-2 nsp16.
Sci.Signal., 14, 2021
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7L6T
 | | Crystal Structure of SARS-CoV-2 Nsp16/10 Heterodimer in Complex with (m7GpppA2m)pUpUpApApA (Cap-1), S-Adenosyl-L-homocysteine (SAH) and two Magnesium (Mg) ions. | | 分子名称: | 2'-O-methyltransferase, CHLORIDE ION, FORMIC ACID, ... | | 著者 | Minasov, G, Shuvalova, L, Rosas-Lemus, M, Kiryukhina, O, Brunzelle, J.S, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2020-12-23 | | 公開日 | 2021-01-06 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Mn 2+ coordinates Cap-0-RNA to align substrates for efficient 2'- O -methyl transfer by SARS-CoV-2 nsp16.
Sci.Signal., 14, 2021
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