7JYY

Crystal Structure of SARS-CoV-2 Nsp16/10 Heterodimer in Complex with (m7GpppA)pUpUpApApA (Cap-0) and S-Adenosylmethionine (SAM).

Summary for 7JYY

Descriptor2'-O-methyltransferase, Non-structural protein 10, RNA (5'-D(*(M7G))-R(P*AP*UP*UP*A)-3'), ... (10 entities in total)
Functional Keywordsstructural genomics, center for structural genomics of infectious diseases, csgid, nsp16, nsp10, complex, viral protein, sam, cap-0, viral protein-rna complex, viral protein/rna
Biological sourceSevere acute respiratory syndrome coronavirus 2 (2019-nCoV)
More
Total number of polymer chains6
Total molecular weight103305.65
Authors
Primary citation
Minasov, G.,Shuvalova, L.,Rosas-Lemus, M.,Kiryukhina, O.,Brunzelle, J.S.,Satchell, K.J.F.,Center for Structural Genomics of Infectious Diseases (CSGID)
Crystal Structure of SARS-CoV-2 Nsp16/10 Heterodimer in Complex with (m7GpppA)pUpUpApApA (Cap-0) and S-Adenosylmethionine (SAM).
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.05 Å)
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliersRNA backbone 0.191300 14.3% 0.29MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
169436
PDB entries from 2020-09-30