7JYY
Crystal Structure of SARS-CoV-2 Nsp16/10 Heterodimer in Complex with (m7GpppA)pUpUpApApA (Cap-0) and S-Adenosylmethionine (SAM).
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | 2'-O-methyltransferase | polymer | 300 | 33556.4 | 2 | UniProt (P0DTD1) Pfam (PF06460) In PDB | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) | NSP16 |
2 | B, D | Non-structural protein 10 | polymer | 141 | 15004.1 | 2 | UniProt (P0DTD1) Pfam (PF09401) In PDB | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) | NSP10 |
3 | E, F | RNA (5'-D(*(M7G))-R(P*AP*UP*UP*A)-3') | polymer | 7 | 2324.4 | 2 | Severe acute respiratory syndrome coronavirus 2 | ||
4 | A, C | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 2 | Chemie (SAM) | |||
5 | A, C | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
6 | A, C | SODIUM ION | non-polymer | 23.0 | 3 | Chemie (NA) | |||
7 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
8 | A, C | FORMIC ACID | non-polymer | 46.0 | 7 | Chemie (FMT) | |||
9 | B, D | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
10 | water | water | 18.0 | 520 | Chemie (HOH) |
Sequence modifications
A, C: 6799 - 7096 (UniProt: P0DTD1)
B, D: 4254 - 4392 (UniProt: P0DTD1)
PDB | External Database | Details |
---|---|---|
Ser 6797 | - | expression tag |
Asn 6798 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Ser 4252 | - | expression tag |
Asn 4253 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 101769.9 | |
Non-Polymers* | Number of molecules | 19 |
Total formula weight | 1533.7 | |
All* | Total formula weight | 103303.6 |