4OJF
 
 | | Humanised 3D6 Fab complexed to amyloid beta 1-8 | | 分子名称: | Amyloid beta A4 protein, Humanised 3D6 Fab Heavy Chain, Humanised 3D6 Fab Light Chain | | 著者 | Miles, L.A, Crespi, G.A.N, Parker, M.W. | | 登録日 | 2014-01-21 | | 公開日 | 2015-01-28 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.998 Å) | | 主引用文献 | Crystallization and preliminary X-ray diffraction analysis of the Fab portion of the Alzheimer's disease immunotherapy candidate bapineuzumab complexed with amyloid-beta
ACTA CRYSTALLOGR.,SECT.F, 70, 2014
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3U0W
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4XXD
 | | Crystal Structure of mid-region amyloid beta capture by solanezumab | | 分子名称: | Amyloid-beta fragment, Fab Heavy Chain, Fab Light Chain | | 著者 | Hermans, S.J, Crespi, G.A.N, Parker, M.W, Miles, L.A. | | 登録日 | 2015-01-30 | | 公開日 | 2015-04-29 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | | 主引用文献 | Molecular basis for mid-region amyloid-beta capture by leading Alzheimer's disease immunotherapies.
Sci Rep, 5, 2015
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4HIX
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8V5T
 | | Crystal structure of Alzheimers disease phospholipase D3 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5'-3' exonuclease PLD3, GLYCEROL, ... | | 著者 | Ishii, K, Hermans, S.J, Nero, T.L, Gorman, M.A, Parker, M.W. | | 登録日 | 2023-12-01 | | 公開日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of Alzheimer's disease phospholipase D3 provides a molecular basis for understanding its normal and pathological functions.
Febs J., 2024
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6D48
 | | Cell Surface Receptor | | 分子名称: | Myeloid cell surface antigen CD33 | | 著者 | Hermans, S.J, Miles, L.A, Parker, M.W. | | 登録日 | 2018-04-17 | | 公開日 | 2019-04-17 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.776 Å) | | 主引用文献 | Small Molecule Binding to Alzheimer Risk Factor CD33 Promotes A beta Phagocytosis.
Iscience, 19, 2019
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6D49
 | | Cell Surface Receptor in Complex with Ligand at 1.80-A Resolution | | 分子名称: | 2-aminoethyl 5-{[(4-cyclohexyl-1H-1,2,3-triazol-1-yl)acetyl]amino}-3,5,9-trideoxy-9-[(4-hydroxy-3,5-dimethylbenzene-1-carbonyl)amino]-D-glycero-alpha-D-galacto-non-2-ulopyranonosyl-(2->6)-beta-D-galactopyranosyl-(1->4)-beta-D-glucopyranoside, GLYCEROL, Myeloid cell surface antigen CD33 | | 著者 | Hermans, S.J, Miles, L.A, Parker, M.W. | | 登録日 | 2018-04-17 | | 公開日 | 2019-04-17 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.801 Å) | | 主引用文献 | Small Molecule Binding to Alzheimer Risk Factor CD33 Promotes A beta Phagocytosis.
Iscience, 19, 2019
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6D4A
 | | Cell Surface Receptor with Bound Ligand at 1.75-A Resolution | | 分子名称: | 2-aminoethyl 5-{[(4-cyclohexyl-1H-1,2,3-triazol-1-yl)acetyl]amino}-3,5,9-trideoxy-9-[(4-hydroxy-3,5-dimethylbenzene-1-carbonyl)amino]-D-glycero-alpha-D-galacto-non-2-ulopyranonosyl-(2->6)-beta-D-galactopyranosyl-(1->4)-beta-D-glucopyranoside, GLYCEROL, Myeloid cell surface antigen CD33 | | 著者 | Hermans, S.J, Miles, L.A, Parker, M.W. | | 登録日 | 2018-04-17 | | 公開日 | 2019-04-17 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.751 Å) | | 主引用文献 | Small Molecule Binding to Alzheimer Risk Factor CD33 Promotes A beta Phagocytosis.
Iscience, 19, 2019
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5BUO
 | | A receptor molecule | | 分子名称: | 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, ACETATE ION, Amyloid beta A4 protein, ... | | 著者 | Gao, C, Crespi, G.A.N, Gorman, M.A, Nero, T.L, Parker, M.W, Miles, L.A. | | 登録日 | 2015-06-04 | | 公開日 | 2016-07-13 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | NULL
To Be Published
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