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7RAF
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BU of 7raf by Molmil
AncAR1-Rev - progesterone - Tif2
分子名称: Ancestral androgen receptor, GLYCEROL, PROGESTERONE, ...
著者Colucci, J.K.
登録日2021-07-01
公開日2022-07-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.551 Å)
主引用文献AncAR1-Rev - progesterone - Tif2
To Be Published
4LTW
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BU of 4ltw by Molmil
Ancestral Ketosteroid Receptor-Progesterone-Mifepristone Complex
分子名称: 11-(4-DIMETHYLAMINO-PHENYL)-17-HYDROXY-13-METHYL-17-PROP-1-YNYL-1,2,6,7,8,11,12,13,14,15,16,17-DODEC AHYDRO-CYCLOPENTA[A]PHENANTHREN-3-ONE, Ancestral Steroid Receptor 2, GLYCEROL, ...
著者Ortlund, E.A, Colucci, J.K.
登録日2013-07-24
公開日2013-12-25
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.045 Å)
主引用文献X-ray crystal structure of the ancestral 3-ketosteroid receptor-progesterone-mifepristone complex shows mifepristone bound at the coactivator binding interface.
Plos One, 8, 2013
4FN9
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BU of 4fn9 by Molmil
X-ray Crystal structure of the Ancestral 3-keto steroid receptor - Progesterone complex
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, GLYCEROL, ...
著者Colucci, J.K, Ortlund, E.A, Thornton, J.W.
登録日2012-06-19
公開日2012-12-26
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Evolution of minimal specificity and promiscuity in steroid hormone receptors.
PLoS Genet., 8, 2012
4FNE
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BU of 4fne by Molmil
X-ray Crystal structure of the Ancestral 3-keto steroid receptor - DOC complex
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, DESOXYCORTICOSTERONE, ...
著者Ortlund, E.A, Colucci, J.K, Thornton, J, Eick, G, Harms, M.
登録日2012-06-19
公開日2012-12-12
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.78 Å)
主引用文献Evolution of minimal specificity and promiscuity in steroid hormone receptors.
PLoS Genet, 8, 2012
8F8M
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BU of 8f8m by Molmil
LRH-1 bound to small molecule Tet and fragment of coactivator Tif2
分子名称: (1~{R},3~{a}~{R},6~{a}~{R})-4-phenyl-3~{a}-(1-phenylethenyl)-5-[9-(1~{H}-1,2,3,4-tetrazol-5-yl)nonyl]-2,3,6,6~{a}-tetrahydro-1~{H}-pentalen-1-ol, Nuclear receptor coactivator 2, Nuclear receptor subfamily 5 group A member 2
著者Cato, M.L, Ortlund, E.A.
登録日2022-11-22
公開日2023-11-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Isosteric improvements to liver receptor homolog-1 small molecule modulators
To Be Published
5UFS
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BU of 5ufs by Molmil
X-Ray Crystal Structure of the Ancestral Glucocorticoid Receptor 2 ligand binding domain in complex with triamcinolone acetonide and SHP coregulator fragment
分子名称: Ancestral Glucocorticoid Receptor2, SHP NR Box 1 Peptide, Triamcinolone acetonide
著者Weikum, E.R, Ortlund, E.A.
登録日2017-01-05
公開日2017-04-26
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.118 Å)
主引用文献Structural Analysis of the Glucocorticoid Receptor Ligand-Binding Domain in Complex with Triamcinolone Acetonide and a Fragment of the Atypical Coregulator, Small Heterodimer Partner.
Mol. Pharmacol., 92, 2017

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件を2024-08-07に公開中

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