4LTW
Ancestral Ketosteroid Receptor-Progesterone-Mifepristone Complex
Summary for 4LTW
| Entry DOI | 10.2210/pdb4ltw/pdb |
| Descriptor | Ancestral Steroid Receptor 2, PROGESTERONE, 11-(4-DIMETHYLAMINO-PHENYL)-17-HYDROXY-13-METHYL-17-PROP-1-YNYL-1,2,6,7,8,11,12,13,14,15,16,17-DODEC AHYDRO-CYCLOPENTA[A]PHENANTHREN-3-ONE, ... (6 entities in total) |
| Functional Keywords | nuclear receptor, steroid receptor, hormone receptor |
| Biological source | Ancestral Gene |
| Total number of polymer chains | 1 |
| Total formula weight | 30472.51 |
| Authors | Ortlund, E.A.,Colucci, J.K. (deposition date: 2013-07-24, release date: 2013-12-25, Last modification date: 2023-09-20) |
| Primary citation | Colucci, J.K.,Ortlund, E.A. X-ray crystal structure of the ancestral 3-ketosteroid receptor-progesterone-mifepristone complex shows mifepristone bound at the coactivator binding interface. Plos One, 8:e80761-e80761, 2013 Cited by PubMed: 24260475DOI: 10.1371/journal.pone.0080761 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.045 Å) |
Structure validation
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