8UW3
| Human LINE-1 retrotransposon ORF2 protein engaged with template RNA in elongation state | 分子名称: | Complementary DNA, LINE-1 retrotransposable element ORF2 protein, THYMIDINE-5'-TRIPHOSPHATE, ... | 著者 | Thawani, A, Florez Ariza, A.J, Collins, K, Nogales, E. | 登録日 | 2023-11-06 | 公開日 | 2023-12-20 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Template and target-site recognition by human LINE-1 in retrotransposition. Nature, 626, 2024
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7BGB
| The H/ACA RNP lobe of human telomerase | 分子名称: | H/ACA ribonucleoprotein complex subunit 1, H/ACA ribonucleoprotein complex subunit 2, H/ACA ribonucleoprotein complex subunit 3, ... | 著者 | Nguyen, T.H.D, Ghanim, G.E, Fountain, A.J, van Roon, A.M.M, Rangan, R, Das, R, Collins, K. | 登録日 | 2021-01-06 | 公開日 | 2021-04-28 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structure of human telomerase holoenzyme with bound telomeric DNA. Nature, 593, 2021
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7BG9
| The catalytic core lobe of human telomerase in complex with a telomeric DNA substrate | 分子名称: | DNA (5'-D(P*TP*TP*AP*GP*GP*G)-3'), Histone H2A, Histone H2B, ... | 著者 | Nguyen, T.H.D, Ghanim, G.E, Fountain, A.J, van Roon, A.M.M, Rangan, R, Das, R, Collins, K. | 登録日 | 2021-01-06 | 公開日 | 2021-04-28 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structure of human telomerase holoenzyme with bound telomeric DNA. Nature, 593, 2021
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8SH4
| Crystal structure of the tRNA (m1G37) methyltransferase apoenzyme from Anaplasma phagocytophilum | 分子名称: | GLYCEROL, tRNA (guanine-N(1)-)-methyltransferase | 著者 | Jannotta, C, Edele, D, Levanti, D, Carson, M, Prucha, G, Caesar, J, Picchiello, C, Collins, K, Garland, E, Handley-Pendleton, J, Hernandez, V, Leffler, S, Williams, D, Stojanoff, V, Perez, A, Halloran, J, Bolen, R. | 登録日 | 2023-04-13 | 公開日 | 2024-04-17 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal structure of the m1G37 tRNA methyltransferase apoenzyme from Anaplasma phagocytophilum To Be Published
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4ERD
| Crystal structure of the C-terminal domain of Tetrahymena telomerase protein p65 in complex with stem IV of telomerase RNA | 分子名称: | 5'-R(P*GP*GP*UP*CP*GP*AP*CP*AP*UP*CP*UP*UP*CP*GP*GP*AP*UP*GP*GP*AP*CP*C)-3', POTASSIUM ION, Telomerase associated protein p65 | 著者 | Singh, M, Wang, Z, Koo, B.-K, Patel, A, Cascio, D, Collins, K, Feigon, J. | 登録日 | 2012-04-19 | 公開日 | 2012-06-20 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (2.589 Å) | 主引用文献 | Structural Basis for Telomerase RNA Recognition and RNP Assembly by the Holoenzyme La Family Protein p65. Mol.Cell, 47, 2012
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4EYT
| Crystal structure of the C-terminal domain of Tetrahymena telomerase protein p65 | 分子名称: | SULFATE ION, Telomerase associated protein p65 | 著者 | Singh, M, Wang, Z, Koo, B.-K, Patel, A, Cascio, D, Collins, K, Feigon, J. | 登録日 | 2012-05-01 | 公開日 | 2012-06-20 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural Basis for Telomerase RNA Recognition and RNP Assembly by the Holoenzyme La Family Protein p65. Mol.Cell, 47, 2012
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2M21
| Solution structure of the Tetrahymena telomerase RNA stem IV terminal loop | 分子名称: | 5'-R(*GP*GP*CP*GP*AP*UP*AP*CP*AP*CP*UP*AP*UP*UP*UP*AP*UP*CP*GP*CP*C)-3' | 著者 | Cash, D.D, Richards, R.J, Wu, H, Trantirek, L, O'Connor, C.M, Feigon, J, Collins, K. | 登録日 | 2012-12-11 | 公開日 | 2013-03-20 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural study of elements of Tetrahymena telomerase RNA stem-loop IV domain important for function. Rna, 12, 2006
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3ZGQ
| Crystal structure of human interferon-induced protein IFIT5 | 分子名称: | DI(HYDROXYETHYL)ETHER, INTERFERON-INDUCED PROTEIN WITH TETRATRICOPEPTIDE REPEATS 5 | 著者 | Katibah, G.E, Lee, H.J, Huizar, J.P, Vogan, J.M, Alber, T, Collins, K. | 登録日 | 2012-12-19 | 公開日 | 2013-01-23 | 最終更新日 | 2013-03-06 | 実験手法 | X-RAY DIFFRACTION (2.203 Å) | 主引用文献 | TRNA Binding, Structure, and Localization of the Human Interferon-Induced Protein Ifit5. Mol.Cell, 49, 2013
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2KYE
| Solution structure of the pseudouridine modified P6.1 hairpin of human telomerase RNA | 分子名称: | RNA (5'-R(*GP*AP*GP*AP*GP*(PSU)P*(PSU)P*GP*GP*GP*CP*(PSU)P*CP*(PSU)P*C)-3') | 著者 | Kim, N.-K, Theimer, C.A, Mitchell, J.R, Collins, K, Feigon, J. | 登録日 | 2010-05-25 | 公開日 | 2010-06-30 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Effect of pseudouridylation on the structure and activity of the catalytically essential P6.1 hairpin in human telomerase RNA. Nucleic Acids Res., 38, 2010
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2LSL
| Solution structure of the C-terminal domain of Tetrahymena telomerase protein p65 | 分子名称: | Telomerase associated protein p65 | 著者 | Singh, M, Wang, Z, Koo, B, Patel, A, Cascio, D, Collins, K, Feigon, J. | 登録日 | 2012-05-01 | 公開日 | 2012-06-20 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural Basis for Telomerase RNA Recognition and RNP Assembly by the Holoenzyme La Family Protein p65. Mol.Cell, 47, 2012
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5KMZ
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3U50
| Crystal Structure of the Tetrahymena telomerase processivity factor Teb1 OB-C | 分子名称: | Telomerase-associated protein 82, ZINC ION | 著者 | Zeng, Z, Huang, J, Yang, Y, Lei, M. | 登録日 | 2011-10-10 | 公開日 | 2011-12-14 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis for Tetrahymena telomerase processivity factor Teb1 binding to single-stranded telomeric-repeat DNA. Proc.Natl.Acad.Sci.USA, 108, 2011
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3U58
| Crystal Structure of the Tetrahymena telomerase processivity factor Teb1 AB | 分子名称: | DNA (5'-D(*GP*GP*GP*T)-3'), Tetrahymena Teb1 AB | 著者 | Zeng, Z, Huang, J, Yang, Y, Lei, M. | 登録日 | 2011-10-11 | 公開日 | 2011-12-28 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.613 Å) | 主引用文献 | Structural basis for Tetrahymena telomerase processivity factor Teb1 binding to single-stranded telomeric-repeat DNA. Proc.Natl.Acad.Sci.USA, 108, 2011
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3U4V
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3U4Z
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6PEY
| MTHFR with mutation Asp120Ala | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Methylenetetrahydrofolate reductase | 著者 | Gallagher, E.L, Gurney, L.A, Frasco, F.G, Trimmer, E, Bolen, R.L, Collins, K, Garland, E, Halloran, J, Handley-Pendelton, J, Hernandez, V, Leffler, S, Perez, A, Soares, A, Stojanoff, V, Williams, D. | 登録日 | 2019-06-21 | 公開日 | 2019-09-25 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.88 Å) | 主引用文献 | Examination of Asp120Ala a Chemically Important Novel Mutation in the Enzyme Mthylenetetrahydrofolate Reductase To be published
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3II5
| The Complex of wild-type B-RAF with Pyrazolo pyrimidine inhibitor | 分子名称: | B-Raf proto-oncogene serine/threonine-protein kinase, N-[3-(3-{4-[(dimethylamino)methyl]phenyl}pyrazolo[1,5-a]pyrimidin-7-yl)phenyl]-3-(trifluoromethyl)benzamide, PHOSPHATE ION | 著者 | Xu, W, Breger, D, Torres, N, Dutia, M, Powell, D, Ciszewski, G. | 登録日 | 2009-07-31 | 公開日 | 2009-11-10 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | 主引用文献 | Non-hinge-binding pyrazolo[1,5-a]pyrimidines as potent B-Raf kinase inhibitors. Bioorg.Med.Chem.Lett., 19, 2009
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5DFM
| Structure of Tetrahymena telomerase p19 fused to MBP | 分子名称: | GLYCEROL, Maltose-binding periplasmic protein,Telomerase-associated protein 19, SULFATE ION, ... | 著者 | Chan, H, Cascio, D, Sawaya, M.R, Feigon, J. | 登録日 | 2015-08-27 | 公開日 | 2015-10-28 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.301 Å) | 主引用文献 | Structure of Tetrahymena telomerase reveals previously unknown subunits, functions, and interactions. Science, 350, 2015
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5DFN
| Structure of Tetrahymena Telomerase P45 C-terminal domain | 分子名称: | Telomerase associated protein p45 | 著者 | Chan, H, Cascio, D, Sawaya, M.R, Feigon, J. | 登録日 | 2015-08-27 | 公開日 | 2015-10-28 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.382 Å) | 主引用文献 | Structure of Tetrahymena telomerase reveals previously unknown subunits, functions, and interactions. Science, 350, 2015
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5DOI
| Crystal structure of Tetrahymena p45N and p19 | 分子名称: | Telomerase associated protein p45, Telomerase-associated protein 19 | 著者 | Wan, B, Tang, T, Wu, J, Lei, M. | 登録日 | 2015-09-11 | 公開日 | 2015-11-25 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The Tetrahymena telomerase p75-p45-p19 subcomplex is a unique CST complex Nat.Struct.Mol.Biol., 22, 2015
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5DOF
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5DOK
| Crystal structure of Tetrahymena p45C | 分子名称: | MAGNESIUM ION, Telomerase associated protein p45 | 著者 | Wan, B, Tang, T, Wu, J, Lei, M. | 登録日 | 2015-09-11 | 公開日 | 2015-11-25 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The Tetrahymena telomerase p75-p45-p19 subcomplex is a unique CST complex Nat.Struct.Mol.Biol., 22, 2015
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