3NZK
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3RQD
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![BU of 3rqd by Molmil](/molmil-images/mine/3rqd) | Ideal Thiolate-Zinc Coordination Geometry in Depsipeptide Binding to Histone Deacetylase 8 | 分子名称: | Histone deacetylase 8, Largazole, POTASSIUM ION, ... | 著者 | Cole, K.E, Dowling, D.P, Christianson, D.W. | 登録日 | 2011-04-28 | 公開日 | 2011-08-24 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.143 Å) | 主引用文献 | Structural basis of the antiproliferative activity of largazole, a depsipeptide inhibitor of the histone deacetylases. J.Am.Chem.Soc., 133, 2011
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5FCW
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![BU of 5fcw by Molmil](/molmil-images/mine/5fcw) | HDAC8 Complexed with a Hydroxamic Acid | 分子名称: | 4-naphthalen-1-yl-~{N}-oxidanyl-benzamide, GLYCEROL, HEXAETHYLENE GLYCOL, ... | 著者 | Cole, K.E, Perry, K. | 登録日 | 2015-12-15 | 公開日 | 2016-10-26 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.979 Å) | 主引用文献 | Structure of 'linkerless' hydroxamic acid inhibitor-HDAC8 complex confirms the formation of an isoform-specific subpocket. J.Struct.Biol., 195, 2016
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4M1B
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5DZ2
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![BU of 5dz2 by Molmil](/molmil-images/mine/5dz2) | Geosmin synthase from Streptomyces coelicolor N-terminal domain complexed with three Mg2+ ions and alendronic acid | 分子名称: | ALENDRONATE, Germacradienol/geosmin synthase, MAGNESIUM ION | 著者 | Harris, G.G, Lombardi, P.M, Pemberton, T.A, Matsui, T, Weiss, T.M, Cole, K.E, Koksal, M, Murphy, F.V, Vedula, L.S, Chou, W.K.W, Cane, D.E, Christianson, D.W. | 登録日 | 2015-09-25 | 公開日 | 2015-12-09 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.111 Å) | 主引用文献 | Structural Studies of Geosmin Synthase, a Bifunctional Sesquiterpene Synthase with alpha alpha Domain Architecture That Catalyzes a Unique Cyclization-Fragmentation Reaction Sequence. Biochemistry, 54, 2015
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5DW7
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![BU of 5dw7 by Molmil](/molmil-images/mine/5dw7) | Crystal structure of the unliganded geosmin synthase N-terminal domain from Streptomyces coelicolor | 分子名称: | Germacradienol/geosmin synthase | 著者 | Lombardi, P.M, Harris, G.G, Pemberton, T.A, Matsui, T, Weiss, T.M, Cole, K.E, Koksal, M, Murphy, F.V, Vedula, L.S, Chou, W.K, Cane, D.E, Christianson, D.W. | 登録日 | 2015-09-22 | 公開日 | 2015-11-25 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.202 Å) | 主引用文献 | Structural Studies of Geosmin Synthase, a Bifunctional Sesquiterpene Synthase with alpha alpha Domain Architecture That Catalyzes a Unique Cyclization-Fragmentation Reaction Sequence. Biochemistry, 54, 2015
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