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7S37
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BU of 7s37 by Molmil
Cas9:sgRNA (S. pyogenes) in the open-protein conformation
分子名称: CRISPR-associated endonuclease Cas9/Csn1, Single-guide RNA
著者Cofsky, J.C, Soczek, K.M, Knott, G.J, Nogales, E, Doudna, J.A.
登録日2021-09-04
公開日2022-04-20
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献CRISPR-Cas9 bends and twists DNA to read its sequence.
Nat.Struct.Mol.Biol., 29, 2022
7S38
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BU of 7s38 by Molmil
Cas9:sgRNA:DNA (S. pyogenes) forming a 3-base-pair R-loop
分子名称: CRISPR-associated endonuclease Cas9/Csn1, Non-target DNA strand, Single-guide RNA, ...
著者Cofsky, J.C, Soczek, K.M, Knott, G.J, Nogales, E, Doudna, J.A.
登録日2021-09-04
公開日2022-04-20
最終更新日2022-05-04
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献CRISPR-Cas9 bends and twists DNA to read its sequence.
Nat.Struct.Mol.Biol., 29, 2022
7S3H
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BU of 7s3h by Molmil
Cas9:sgRNA:DNA (S. pyogenes) with 0 RNA:DNA base pairs, open-protein/linear-DNA conformation
分子名称: CRISPR-associated endonuclease Cas9/Csn1, Non-target DNA strand, Single-guide RNA, ...
著者Cofsky, J.C, Soczek, K.M, Knott, G.J, Nogales, E, Doudna, J.A.
登録日2021-09-06
公開日2022-04-20
最終更新日2022-05-04
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献CRISPR-Cas9 bends and twists DNA to read its sequence.
Nat.Struct.Mol.Biol., 29, 2022
7S36
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BU of 7s36 by Molmil
Cas9:sgRNA:DNA (S. pyogenes) with 0 RNA:DNA base pairs, closed-protein/bent-DNA conformation
分子名称: CRISPR-associated endonuclease Cas9/Csn1, Non-target DNA strand, Single-guide RNA, ...
著者Cofsky, J.C, Soczek, K.M, Knott, G.J, Nogales, E, Doudna, J.A.
登録日2021-09-04
公開日2022-04-20
最終更新日2022-05-04
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献CRISPR-Cas9 bends and twists DNA to read its sequence.
Nat.Struct.Mol.Biol., 29, 2022
7THB
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BU of 7thb by Molmil
Crystal structure of an RNA-5'/DNA-3' strand exchange junction
分子名称: DNA (5'-D(*GP*AP*TP*GP*CP*TP*C)-3'), DNA (5'-D(*GP*TP*AP*AP*GP*CP*AP*GP*CP*AP*TP*C)-3'), RNA (5'-R(*AP*GP*CP*UP*UP*AP*C)-3')
著者Cofsky, J.C, Knott, G.J, Gee, C.L, Doudna, J.A.
登録日2022-01-10
公開日2022-04-27
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Crystal structure of an RNA/DNA strand exchange junction.
Plos One, 17, 2022
5WDP
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BU of 5wdp by Molmil
H-Ras mutant L120A bound to GMP-PNP at 277K
分子名称: CALCIUM ION, GTPase HRas, MAGNESIUM ION, ...
著者Cofsky, J.C, Bandaru, P, Gee, C.L, Kuriyan, J.
登録日2017-07-05
公開日2017-07-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Deconstruction of the Ras switching cycle through saturation mutagenesis.
Elife, 6, 2017
5WDO
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BU of 5wdo by Molmil
H-Ras bound to GMP-PNP at 277K
分子名称: CALCIUM ION, GTPase HRas, MAGNESIUM ION, ...
著者Cofsky, J.C, Bandaru, P, Gee, C.L, Kuriyan, J.
登録日2017-07-05
公開日2017-07-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Deconstruction of the Ras switching cycle through saturation mutagenesis.
Elife, 6, 2017
5WDQ
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BU of 5wdq by Molmil
H-Ras mutant L120A bound to GMP-PNP at 100K
分子名称: ACETATE ION, CALCIUM ION, GTPase HRas, ...
著者Bandaru, P, Gee, C.L, Kuriyan, J.
登録日2017-07-05
公開日2017-07-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Deconstruction of the Ras switching cycle through saturation mutagenesis.
Elife, 6, 2017
5WDR
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BU of 5wdr by Molmil
Choanoflagellate Salpingoeca rosetta Ras with GMP-PNP
分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras protein, ...
著者Kondo, Y, Gee, C.L, Kuriyan, J.
登録日2017-07-05
公開日2017-07-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Deconstruction of the Ras switching cycle through saturation mutagenesis.
Elife, 6, 2017
5W1H
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BU of 5w1h by Molmil
Crystal structure of LbaCas13a (C2c2) bound to mature crRNA (24-nt spacer)
分子名称: GLYCEROL, IODIDE ION, LbaCas13a (C2c2), ...
著者Knott, G.J, Doudna, J.A.
登録日2017-06-03
公開日2017-09-13
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Guide-bound structures of an RNA-targeting A-cleaving CRISPR-Cas13a enzyme.
Nat. Struct. Mol. Biol., 24, 2017
5W1I
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BU of 5w1i by Molmil
Crystal structure of LbaCas13a (C2c2) bound to mature crRNA (20-nt spacer)
分子名称: IODIDE ION, LbaCas13a (C2c2), mature crRNA
著者Knott, G.J, Doudna, J.A.
登録日2017-06-03
公開日2017-09-13
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Guide-bound structures of an RNA-targeting A-cleaving CRISPR-Cas13a enzyme.
Nat. Struct. Mol. Biol., 24, 2017
5WLH
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BU of 5wlh by Molmil
Crystal structure of LbaCas13a H328A (C2c2) bound to pre-crRNA (24-nt spacer)
分子名称: GLYCEROL, IODIDE ION, LbaCas13a H328A (C2c2), ...
著者Knott, G.J, Doudna, J.A.
登録日2017-07-26
公開日2017-09-13
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.80001032 Å)
主引用文献Guide-bound structures of an RNA-targeting A-cleaving CRISPR-Cas13a enzyme.
Nat. Struct. Mol. Biol., 24, 2017
5WDS
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BU of 5wds by Molmil
Choanoflagellate Salpingoeca rosetta Ras with GDP bound
分子名称: GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Kondo, Y, Gee, C.L, Kuriyan, J.
登録日2017-07-05
公開日2017-07-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Deconstruction of the Ras switching cycle through saturation mutagenesis.
Elife, 6, 2017
5VGB
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BU of 5vgb by Molmil
Crystal structure of NmeCas9 HNH domain bound to anti-CRISPR AcrIIC1
分子名称: Anti-CRISPR protein (AcrIIC1), CRISPR-associated endonuclease Cas9, GLYCEROL, ...
著者Harrington, L.B, Doxzen, K.W, Ma, E, Knott, G.J, Kranzusch, P.J, Doudna, J.A.
登録日2017-04-10
公開日2017-08-30
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.497 Å)
主引用文献A Broad-Spectrum Inhibitor of CRISPR-Cas9.
Cell, 170, 2017

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件を2024-07-17に公開中

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