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6X1K
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BU of 6x1k by Molmil
Solution NMR structure of de novo designed TMB2.3
分子名称: De novo designed transmembrane beta-barrel TMB2.3
著者Liang, B, Vorobieva, A.A, Chow, C.M, Baker, D, Tamm, L.K.
登録日2020-05-19
公開日2021-02-17
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献De novo design of transmembrane beta barrels.
Science, 371, 2021
7UWY
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BU of 7uwy by Molmil
NMR solution structure of the De novo designed small beta-barrel protein 29_bp_sh3
分子名称: De novo designed small beta-barrel protein 29_bp_sh3
著者Peterson, F.C, Kim, D.E, Jensen, D.R, Saleem, A, Chow, C.M, Volkman, B.F, Baker, D.
登録日2022-05-04
公開日2023-03-22
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献De novo design of small beta barrel proteins.
Proc.Natl.Acad.Sci.USA, 120, 2023
7UWZ
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BU of 7uwz by Molmil
NMR solution structure of the De novo designed small beta-barrel protein 33_bp_sh3
分子名称: De novo designed small beta-barrel protein 33_bp_sh3
著者Peterson, F.C, Kim, D.E, Jensen, D.R, Saleem, A, Chow, C.M, Volkman, B.F, Baker, D.
登録日2022-05-04
公開日2023-03-22
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献De novo design of small beta barrel proteins.
Proc.Natl.Acad.Sci.USA, 120, 2023
7CBC
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BU of 7cbc by Molmil
Crystal structure of a de novo designed switch protein caging a hemagglutinin binder
分子名称: De novo designed switch protein caging a hemagglutinin binder (sCageHA267_1S), ETHANOL
著者Lee, H, Oh, B.-H, Baker, D.
登録日2020-06-11
公開日2020-12-23
最終更新日2021-03-31
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献De novo design of modular and tunable protein biosensors.
Nature, 591, 2021
6W2Q
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BU of 6w2q by Molmil
Junction 34, DHR53-DHR4
分子名称: CALCIUM ION, Junction 34
著者Bick, M.J, Brunette, T.J, Baker, D.
登録日2020-03-08
公開日2020-04-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Modular repeat protein sculpting using rigid helical junctions.
Proc.Natl.Acad.Sci.USA, 117, 2020
6W3D
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BU of 6w3d by Molmil
Rd1NTF2_05 with long sheet
分子名称: Rd1NTF2_05
著者Bick, M.J, Basanta, B, Sankaran, B, Baker, D.
登録日2020-03-09
公開日2020-04-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.38 Å)
主引用文献An enumerative algorithm for de novo design of proteins with diverse pocket structures.
Proc.Natl.Acad.Sci.USA, 117, 2020
6W3G
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BU of 6w3g by Molmil
Rd1NTF2_04 with long sheet
分子名称: Rd1NTF2_04
著者Bick, M.J, Basanta, B, Sankaran, B, Baker, D.
登録日2020-03-09
公開日2020-04-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献An enumerative algorithm for de novo design of proteins with diverse pocket structures.
Proc.Natl.Acad.Sci.USA, 117, 2020
6W2W
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BU of 6w2w by Molmil
Junction 24, DHR14-DHR18
分子名称: Junction 24 DHR14-DHR18
著者Bick, M.J, Brunette, T.J, Baker, D.
登録日2020-03-08
公開日2020-04-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Modular repeat protein sculpting using rigid helical junctions.
Proc.Natl.Acad.Sci.USA, 117, 2020
6W2R
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BU of 6w2r by Molmil
Junction 19, DHR54-DHR79
分子名称: Junction 19 DHR54-DHR79
著者Bick, M.J, Brunette, T.J, Baker, D.
登録日2020-03-08
公開日2020-04-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.344 Å)
主引用文献Modular repeat protein sculpting using rigid helical junctions.
Proc.Natl.Acad.Sci.USA, 117, 2020
6W3F
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BU of 6w3f by Molmil
Rd1NTF2_05_I64F_A80G_T94P_D101K_L106W
分子名称: Rd1NTF2_05_I64F_A80G_T94P_D101K_L106W
著者Bick, M.J, Basanta, B, Sankaran, B, Baker, D.
登録日2020-03-09
公開日2020-04-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献An enumerative algorithm for de novo design of proteins with diverse pocket structures.
Proc.Natl.Acad.Sci.USA, 117, 2020
6W40
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BU of 6w40 by Molmil
An enumerative algorithm for de novo design of proteins with diverse pocket structures
分子名称: DENOVO NTF2
著者Bera, A.K, Basanta, B, Sankaran, B, Baker, D.
登録日2020-03-09
公開日2020-04-08
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献An enumerative algorithm for de novo design of proteins with diverse pocket structures.
Proc.Natl.Acad.Sci.USA, 117, 2020
6XNS
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BU of 6xns by Molmil
C3_crown-05
分子名称: C3_crown-05
著者Bick, M.J, Hsia, Y, Sankaran, B, Baker, D.
登録日2020-07-04
公開日2020-12-23
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.19 Å)
主引用文献Design of multi-scale protein complexes by hierarchical building block fusion.
Nat Commun, 12, 2021
6XT4
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BU of 6xt4 by Molmil
C3_HD-1069 (1BH-69) - fusion protein of helical bundle and repeat protein
分子名称: 1BH_69
著者Bick, M.J, Hsia, Y, Sankaran, B, Baker, D.
登録日2020-07-17
公開日2020-12-23
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Design of multi-scale protein complexes by hierarchical building block fusion.
Nat Commun, 12, 2021
6XSS
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BU of 6xss by Molmil
CryoEM structure of designed helical fusion protein C4_nat_HFuse-7900
分子名称: C4_nat_HFuse-7900
著者Redler, R.L, Edman, N.I, Baker, D, Ekiert, D, Bhabha, G.
登録日2020-07-16
公開日2020-12-23
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Design of multi-scale protein complexes by hierarchical building block fusion.
Nat Commun, 12, 2021
6X9Z
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BU of 6x9z by Molmil
De novo design of transmembrane beta-barrels
分子名称: Transmembrane beta-barrels
著者Bera, A.K, Vorobieva, A.A, Kang, A.S, Baker, D.
登録日2020-06-03
公開日2021-02-17
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献De novo design of transmembrane beta barrels.
Science, 371, 2021
6XI6
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BU of 6xi6 by Molmil
Hierarchical design of multi-scale protein complexes by combinatorial assembly of oligomeric helical bundle and repeat protein building blocks
分子名称: helical fusion design
著者Bera, A.K, Hsia, Y, Kang, A.S, Shankaran, B, Baker, D.
登録日2020-06-19
公開日2021-06-02
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Design of multi-scale protein complexes by hierarchical building block fusion.
Nat Commun, 12, 2021
6XH5
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BU of 6xh5 by Molmil
Hierarchical design of multi-scale protein complexes by combinatorial assembly of oligomeric helical bundle and repeat protein building blocks
分子名称: helical fusion design
著者Bera, A.K, Hsia, Y, Kang, A.S, Baker, D.
登録日2020-06-18
公開日2021-06-02
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.32 Å)
主引用文献Design of multi-scale protein complexes by hierarchical building block fusion.
Nat Commun, 12, 2021
7KUW
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BU of 7kuw by Molmil
High-throughput design and refinement of stable proteins using sequence-only models
分子名称: Sequence-Based Designed Protein nmt_0994_guided_02
著者Bera, A.K, Stewart, L, Kang, A.S, Baker, D.
登録日2020-11-25
公開日2021-12-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.43 Å)
主引用文献Large-scale design and refinement of stable proteins using sequence-only models.
Plos One, 17, 2022
7M0Q
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BU of 7m0q by Molmil
Crystal structure of deep network hallucinated protein 0738_mod
分子名称: Network hallucinated protein 0738_mod
著者Pellock, S.J, Bera, A.K, Anishchenko, I, Baker, D.
登録日2021-03-11
公開日2021-12-29
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献De novo protein design by deep network hallucination.
Nature, 600, 2021
7LMX
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BU of 7lmx by Molmil
A HIGHLY SPECIFIC INHIBITOR OF INTEGRIN ALPHA-V BETA-6 WITH A DISULFIDE
分子名称: Integrin inhibitor
著者Dong, X, Bera, A.K, Roy, A, Shi, L, Springer, T.A, Baker, D.
登録日2021-02-06
公開日2022-08-10
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献De novo design of highly selective miniprotein inhibitors of integrins alpha v beta 6 and alpha v beta 8.
Nat Commun, 14, 2023
7LMV
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BU of 7lmv by Molmil
SPECIFIC INHIBITOR OF INTEGRIN ALPHA-V BETA-6
分子名称: Integrin inhibitor
著者Dong, X, Bera, A.K, Roy, A, Shi, L, Springer, T.A, Baker, D.
登録日2021-02-05
公開日2022-08-10
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献De novo design of highly selective miniprotein inhibitors of integrins alpha v beta 6 and alpha v beta 8.
Nat Commun, 14, 2023
7M5T
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BU of 7m5t by Molmil
Solution NMR structure of de novo designed protein 0515
分子名称: De novo designed protein 0515
著者Ramelot, T.A, Hao, J, Baker, D, Montelione, G.T.
登録日2021-03-24
公開日2021-12-15
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献De novo protein design by deep network hallucination.
Nature, 600, 2021
8TCF
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BU of 8tcf by Molmil
Integrin alpha-v beta-8 in complex with minibinder B8_BP_dsulf
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Campbell, M.G, Fernandez, A, Roy, A, Kraft, J, Baker, D.
登録日2023-06-30
公開日2023-09-27
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献De novo design of highly selective miniprotein inhibitors of integrins alpha v beta 6 and alpha v beta 8.
Nat Commun, 14, 2023
8TCG
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BU of 8tcg by Molmil
Integrin alpha-v beta-6 in complex with minibinder B6_BP_dslf
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Integrin alpha-V heavy chain, ...
著者Campbell, M.G, Fernandez, A, Roy, A, Kraft, J, Baker, D.
登録日2023-06-30
公開日2023-09-27
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献De novo design of highly selective miniprotein inhibitors of integrins alpha v beta 6 and alpha v beta 8.
Nat Commun, 14, 2023
6OHH
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BU of 6ohh by Molmil
Structure of EF1p2_mFAP2b bound to DFHBI
分子名称: (5Z)-5-(3,5-difluoro-4-hydroxybenzylidene)-2,3-dimethyl-3,5-dihydro-4H-imidazol-4-one, CALCIUM ION, EF1p2_mFAP2b
著者Doyle, L.A, Stoddard, B.L.
登録日2019-04-05
公開日2020-04-08
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Incorporation of sensing modalities into de novo designed fluorescence-activating proteins
Nat Commun, 12, 2021

 

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