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7RH2
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BU of 7rh2 by Molmil
IRF4 Transcription factor mutant -K59R
分子名称: DNA (5'-D(*CP*AP*AP*CP*TP*GP*AP*AP*AP*CP*CP*GP*AP*GP*AP*AP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*TP*TP*CP*TP*CP*GP*GP*TP*TP*TP*CP*AP*GP*TP*TP*G)-3'), ICSAT transcription factor
著者Williams, S.J, Sundararaj, S, Casarotto, M.G.
登録日2021-07-16
公開日2022-05-25
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.47 Å)
主引用文献The molecular basis for the development of adult T-cell leukemia/lymphoma in patients with an IRF4 K59R mutation.
Protein Sci., 31, 2022
1JZP
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BU of 1jzp by Molmil
Modified Peptide A (D18-A1) of the Rabbit Skeletal Dihydropyridine Receptor
分子名称: Skeletal Dihydropydrine Receptor
著者Green, D, Pace, S, Sakowska, M, Dulhunty, A.F, Casarotto, M.G.
登録日2001-09-17
公開日2002-03-20
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献The three-dimensional structural surface of two beta-sheet scorpion toxins mimics that of an alpha-helical dihydropyridine receptor segment.
Biochem.J., 370, 2003
7JM4
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BU of 7jm4 by Molmil
IRF Transcription Factor
分子名称: Interferon regulatory factor 4, Interferon-Stimulated Response Elements
著者Sundararaj, S, Williams, S.J, Casarotto, M.G.
登録日2020-07-31
公開日2021-03-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Structural determinants of the IRF4/DNA homodimeric complex.
Nucleic Acids Res., 49, 2021
1DU1
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BU of 1du1 by Molmil
PEPTIDE FRAGMENT THR671-LEU690 OF THE RABBIT SKELETAL DIHYDROPYRIDINE RECEPTOR
分子名称: SKELETAL DIHYDROPYRIDINE RECEPTOR
著者Casarotto, M, Dulhunty, A.
登録日2000-01-13
公開日2000-07-19
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献A structural requirement for activation of skeletal ryanodine receptors by peptides of the dihydropyridine receptor II-III loop.
J.Biol.Chem., 275, 2000
6PNN
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Human GSTO1-1 complexed with 2-chloro-N-(4-chloro-3-(N-(2-methoxyethyl)-N-methylsulfamoyl)phenyl)acetamide
分子名称: 2-chloro-N-{4-chloro-3-[(2-methoxyethyl)(methyl)sulfamoyl]phenyl}acetamide, Glutathione S-transferase omega-1, L(+)-TARTARIC ACID, ...
著者Oakley, A.J.
登録日2019-07-02
公開日2019-07-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Development of Benzenesulfonamide Derivatives as Potent Glutathione Transferase Omega-1 Inhibitors.
J.Med.Chem., 63, 2020
6PNM
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Human GSTO1-1 complexed with 2-chloro-N-(4-chloro-3-(morpholinosulfonyl)phenyl)acetamide
分子名称: 2-chloro-N-{4-chloro-3-[(morpholin-4-yl)sulfonyl]phenyl}acetamide, Glutathione S-transferase omega-1, L(+)-TARTARIC ACID, ...
著者Oakley, A.J.
登録日2019-07-02
公開日2019-07-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Development of Benzenesulfonamide Derivatives as Potent Glutathione Transferase Omega-1 Inhibitors.
J.Med.Chem., 63, 2020
6PNO
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BU of 6pno by Molmil
Human GSTO1-1 complexed with 2-chloro-N-(4-chloro-3-(N-isopropylsulfamoyl)phenyl)acetamide
分子名称: 2-chloro-N-{4-chloro-3-[(propan-2-yl)sulfamoyl]phenyl}acetamide, Glutathione S-transferase omega-1, L(+)-TARTARIC ACID, ...
著者Oakley, A.J.
登録日2019-07-02
公開日2019-07-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Development of Benzenesulfonamide Derivatives as Potent Glutathione Transferase Omega-1 Inhibitors.
J.Med.Chem., 63, 2020
5V3Q
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Human GSTO1-1 complexed with ML175
分子名称: Glutathione S-transferase omega-1, N-{3-[(2-chloro-acetyl)-(4-nitro-phenyl)-amino]-propyl}-2,2,2-trifluoro-acetamide, SULFATE ION
著者Oakley, A.J.
登録日2017-03-07
公開日2017-12-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献GSTO1-1 plays a pro-inflammatory role in models of inflammation, colitis and obesity.
Sci Rep, 7, 2017
4ZW2
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Crystal structure of the Mouse voltage gated calcium channel beta subunit isoform 1a in complex with Alpha Interaction Domain peptide.
分子名称: TRIETHYLENE GLYCOL, Voltage-dependent L-type calcium channel subunit alpha-1S, Voltage-dependent L-type calcium channel subunit beta-1,Voltage-dependent L-type calcium channel subunit beta-1
著者Norris, N.C, Oakley, A.J.
登録日2015-05-19
公開日2016-06-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Structural and biophysical analyses of the skeletal dihydropyridine receptor beta subunit beta 1a reveal critical roles of domain interactions for stability.
J. Biol. Chem., 292, 2017
3LFL
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Crystal Structure of human Glutathione Transferase Omega 1, delta 155
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, GLUTATHIONE, Glutathione S-transferase omega-1
著者Brock, J.
登録日2010-01-18
公開日2010-11-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Novel folding and stability defects cause a deficiency of human glutathione transferase omega 1.
J.Biol.Chem., 286, 2011

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件を2024-08-07に公開中

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