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4YZS
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BU of 4yzs by Molmil
Crystal structures reveal transient PERK luminal domain tetramerization in ER stress signaling
分子名称: Eukaryotic translation initiation factor 2-alpha kinase 3, TUNGSTEN ION
著者Carrara, M, Prischi, F, Ali, M.M.U.
登録日2015-03-25
公開日2015-05-13
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (3.14 Å)
主引用文献Crystal structures reveal transient PERK luminal domain tetramerization in endoplasmic reticulum stress signaling.
Embo J., 34, 2015
4YZY
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BU of 4yzy by Molmil
Crystal structures reveal transient PERK luminal domain tetramerization in ER stress signaling
分子名称: Eukaryotic translation initiation factor 2-alpha kinase 3
著者Carrara, M, Prischi, F, Ali, M.M.U.
登録日2015-03-25
公開日2015-05-13
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structures reveal transient PERK luminal domain tetramerization in endoplasmic reticulum stress signaling.
Embo J., 34, 2015
6EM9
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BU of 6em9 by Molmil
S.aureus ClpC resting state, asymmetric map
分子名称: ATP-dependent Clp protease ATP-binding subunit ClpC
著者Carroni, M, Mogk, A, Bukau, B, Franke, K.
登録日2017-10-01
公開日2017-12-27
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (8.4 Å)
主引用文献Regulatory coiled-coil domains promote head-to-head assemblies of AAA+ chaperones essential for tunable activity control.
Elife, 6, 2017
6EMW
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BU of 6emw by Molmil
Structure of S.aureus ClpC in complex with MecA
分子名称: ATP-dependent Clp protease ATP-binding subunit, ATP-dependent Clp protease ATP-binding subunit ClpC, Adapter protein MecA, ...
著者Carroni, M, Mogk, A, Bukau, B, Franke, K.
登録日2017-10-03
公開日2017-12-27
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (11 Å)
主引用文献Regulatory coiled-coil domains promote head-to-head assemblies of AAA+ chaperones essential for tunable activity control.
Elife, 6, 2017
6EM8
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BU of 6em8 by Molmil
S.aureus ClpC resting state, C2 symmetrised
分子名称: ATP-dependent Clp protease ATP-binding subunit ClpC
著者Carroni, M, Mogk, A.
登録日2017-10-01
公開日2017-12-27
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (8.4 Å)
主引用文献Regulatory coiled-coil domains promote head-to-head assemblies of AAA+ chaperones essential for tunable activity control.
Elife, 6, 2017
4D2Q
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BU of 4d2q by Molmil
Negative-stain electron microscopy of E. coli ClpB mutant E432A (BAP form bound to ClpP)
分子名称: CLPB
著者Carroni, M, Kummer, E, Oguchi, Y, Clare, D.K, Wendler, P, Sinning, I, Kopp, J, Mogk, A, Bukau, B, Saibil, H.R.
登録日2014-05-12
公開日2014-06-04
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (18 Å)
主引用文献Head-to-Tail Interactions of the Coiled-Coil Domains Regulate Clpb Activity and Cooperation with Hsp70 in Protein Disaggregation.
Elife, 3, 2014
4D2X
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BU of 4d2x by Molmil
Negative-stain electron microscopy of E. coli ClpB of Y503D hyperactive mutant (BAP form bound to ClpP)
分子名称: CHAPERONE PROTEIN CLPB
著者Carroni, M, Kummer, E, Oguchi, Y, Clare, D.K, Wendler, P, Sinning, I, Kopp, J, Mogk, A, Bukau, B, Saibil, H.R.
登録日2014-05-13
公開日2014-06-04
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (20 Å)
主引用文献Head-to-Tail Interactions of the Coiled-Coil Domains Regulate Clpb Activity and Cooperation with Hsp70 in Protein Disaggregation.
Elife, 3, 2014
4D2U
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BU of 4d2u by Molmil
Negative-stain electron microscopy of E. coli ClpB (BAP form bound to ClpP)
分子名称: CHAPERONE PROTEIN CLPB
著者Carroni, M, Kummer, E, Oguchi, Y, Clare, D.K, Wendler, P, Sinning, I, Kopp, J, Mogk, A, Bukau, B, Saibil, H.R.
登録日2014-05-13
公開日2014-06-04
最終更新日2024-11-13
実験手法ELECTRON MICROSCOPY (17 Å)
主引用文献Head-to-Tail Interactions of the Coiled-Coil Domains Regulate Clpb Activity and Cooperation with Hsp70 in Protein Disaggregation.
Elife, 3, 2014
8PYQ
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BU of 8pyq by Molmil
10 micrometer HEWL crystals solved at room-temperature using fixed-target serial crystallography.
分子名称: CHLORIDE ION, Lysozyme C, SODIUM ION
著者Mason, T.J, Carrillo, M, Beale, J.H, Padeste, C.
登録日2023-07-25
公開日2023-08-16
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Micro-structured polymer fixed targets for serial crystallography at synchrotrons and XFELs.
Iucrj, 10, 2023
8PYO
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BU of 8pyo by Molmil
5 micrometer HEWL crystals solved at room-temperature using fixed-target serial crystallography.
分子名称: CHLORIDE ION, Lysozyme C, SODIUM ION
著者Mason, T.J, Carrillo, M, Beale, J.H, Padeste, C.
登録日2023-07-25
公開日2023-08-16
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献Micro-structured polymer fixed targets for serial crystallography at synchrotrons and XFELs.
Iucrj, 10, 2023
8PYP
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BU of 8pyp by Molmil
25 micrometer HEWL crystals solved at room-temperature using fixed-target serial crystallography.
分子名称: CHLORIDE ION, Lysozyme C, SODIUM ION
著者Mason, T.J, Carrillo, M, Beale, J.H, Padeste, C.
登録日2023-07-25
公開日2023-08-16
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Micro-structured polymer fixed targets for serial crystallography at synchrotrons and XFELs.
Iucrj, 10, 2023
7QVK
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BU of 7qvk by Molmil
NM-02 in complex with HER2-ECD
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, NM-02, Receptor tyrosine-protein kinase erbB-2, ...
著者Cowan, R, Hall, G, Carr, M.
登録日2022-01-21
公開日2023-02-01
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Co-crystallisation and humanisation of an anti-HER2 single-domain antibody as a theranostic tool.
Plos One, 18, 2023
1POS
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BU of 1pos by Molmil
CRYSTAL STRUCTURE OF A NOVEL DISULFIDE-LINKED "TREFOIL" MOTIF FOUND IN A LARGE FAMILY OF PUTATIVE GROWTH FACTORS
分子名称: PORCINE PANCREATIC SPASMOLYTIC POLYPEPTIDE
著者De, A, Brown, D, Gorman, M, Carr, M, Sanderson, M.R, Freemont, P.S.
登録日1993-10-08
公開日1994-01-31
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of a disulfide-linked "trefoil" motif found in a large family of putative growth factors.
Proc.Natl.Acad.Sci.USA, 91, 1994
8BYP
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BU of 8byp by Molmil
Botulinum neurotoxin serotype X in complex with NTNH/X
分子名称: Botulinum neurotoxin type X, NTNH/X
著者Martinez-Carranza, M, Skerlova, J, Stenmark, P.
登録日2022-12-15
公開日2023-02-08
最終更新日2025-04-02
実験手法ELECTRON MICROSCOPY (3.12 Å)
主引用文献Activity of botulinum neurotoxin X and its structure when shielded by a non-toxic non-hemagglutinin protein.
Commun Chem, 7, 2024
1XU6
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BU of 1xu6 by Molmil
Structure of the C-terminal domain from Trypanosoma brucei Variant Surface Glycoprotein MITat1.2
分子名称: Variant surface glycoprotein MITAT 1.2
著者Chattopadhyay, A, Jones, N.G, Nietlispach, D, Nielsen, P.R, Voorheis, H.P, Mott, H.R, Carrington, M.
登録日2004-10-25
公開日2004-11-30
最終更新日2024-10-30
実験手法SOLUTION NMR
主引用文献Structure of the C-terminal domain from Trypanosoma brucei variant surface glycoprotein MITat1.2
J.Biol.Chem., 280, 2004
8C5Y
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BU of 8c5y by Molmil
RPA tetrameric supercomplex from Pyrococcus abyssi
分子名称: RPA14 subunit of the hetero-oligomeric complex involved in homologous recombination, RPA32 subunit of the hetero-oligomeric complex involved in homologous recombination, Replication factor A, ...
著者Madru, C, Martinez-Carranza, M, Legrand, P, Sauguet, L.
登録日2023-01-10
公開日2023-05-03
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.35 Å)
主引用文献DNA-binding mechanism and evolution of replication protein A.
Nat Commun, 14, 2023
8C5Z
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BU of 8c5z by Molmil
RPA tetrameric supercomplex with AROD-OB-1
分子名称: RPA14 subunit of the hetero-oligomeric complex involved in homologous recombination, RPA32 subunit of the hetero-oligomeric complex involved in homologous recombination, Replication factor A, ...
著者Madru, C, Martinez-Carranza, M, Legrand, P, Sauguet, L.
登録日2023-01-10
公開日2023-05-10
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献DNA-binding mechanism and evolution of replication protein A.
Nat Commun, 14, 2023
6ZJK
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BU of 6zjk by Molmil
Ribonucleotide reductase R2 subunit from Clostridium botulinum
分子名称: FE (III) ION, GLYCEROL, Ribonucleoside-diphosphate reductase subunit beta
著者Martinez-Carranza, M, Stenmark, P.
登録日2020-06-29
公開日2020-09-30
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A ribonucleotide reductase from Clostridium botulinum reveals distinct evolutionary pathways to regulation via the overall activity site.
J.Biol.Chem., 295, 2020
7PFP
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BU of 7pfp by Molmil
Full-length cryo-EM structure of the native human uromodulin (UMOD)/Tamm-Horsfall protein (THP) filament
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Uromodulin, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Jovine, L, Xu, C, Stsiapanava, A, Carroni, M, Tunyasuvunakool, K, Jumper, J, Wu, B.
登録日2021-08-11
公開日2022-03-16
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (6.1 Å)
主引用文献Structure of the decoy module of human glycoprotein 2 and uromodulin and its interaction with bacterial adhesin FimH.
Nat.Struct.Mol.Biol., 29, 2022
8C5H
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BU of 8c5h by Molmil
NbSyt1 anti-(rat Synaptotagmin-1) nanobody bound to target cytosolic domain of Synaptotagmin-1
分子名称: CALCIUM ION, GLYCEROL, NbSyt1 nanobody, ...
著者Martinez-Carranza, M, Stenmark, P.
登録日2023-01-09
公開日2023-08-02
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献A Versatile Synaptotagmin-1 Nanobody Provides Perturbation-Free Live Synaptic Imaging And Low Linkage-Error in Super-Resolution Microscopy.
Small Methods, 7, 2023
7Q3N
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BU of 7q3n by Molmil
Cryo-EM of the complex between human uromodulin (UMOD)/Tamm-Horsfall protein (THP) and the FimH lectin domain from uropathogenic E. coli
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Type 1 fimbiral adhesin FimH, ...
著者Jovine, L, Xu, C, Stsiapanava, A, Carroni, M, Tunyasuvunakool, K, Jumper, J, Wu, B.
登録日2021-10-28
公開日2022-03-16
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (7.4 Å)
主引用文献Structure of the decoy module of human glycoprotein 2 and uromodulin and its interaction with bacterial adhesin FimH.
Nat.Struct.Mol.Biol., 29, 2022
7QFQ
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BU of 7qfq by Molmil
Cryo-EM structure of Botulinum neurotoxin serotype B
分子名称: Botulinum neurotoxin type B
著者Kosenina, S, Martinez-Carranza, M, Davies, J.R, Masuyer, G, Stenmark, P.
登録日2021-12-06
公開日2022-01-26
最終更新日2024-11-13
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural Analysis of Botulinum Neurotoxins Type B and E by Cryo-EM.
Toxins, 14, 2021
7QFP
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Cryo-EM structure of Botulinum neurotoxin serotype E
分子名称: Botulinum neurotoxin
著者Kosenina, S, Martinez-Carranza, M, Davies, J.R, Masuyer, G, Stenmark, P.
登録日2021-12-06
公開日2022-01-26
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural Analysis of Botulinum Neurotoxins Type B and E by Cryo-EM.
Toxins, 14, 2021
6I2G
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BU of 6i2g by Molmil
ALFA-tag binding nanobody (NbALFA) bound to ALFA-tag peptide.
分子名称: ALFA nanobody, N7P-SER-ARG-LEU-GLU-GLU-GLU-LEU-ARG-ARG-ARG-LEU-THR-GLU-LPD, SULFATE ION
著者Martinez-Carranza, M, Stenmark, P.
登録日2018-11-01
公開日2019-09-25
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The ALFA-tag is a highly versatile tool for nanobody-based bioscience applications.
Nat Commun, 10, 2019
9F29
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BU of 9f29 by Molmil
Pyrococcus abyssi PolD in complex with Rpa2 winged-helix domain class 1 (composite map)
分子名称: DNA polymerase II large subunit, DNA polymerase II small subunit, FE (III) ION, ...
著者Martinez-Carranza, M, Sauguet, L.
登録日2024-04-22
公開日2024-12-04
最終更新日2025-01-22
実験手法ELECTRON MICROSCOPY (2.94 Å)
主引用文献Communication between DNA polymerases and Replication Protein A within the archaeal replisome.
Nat Commun, 15, 2024

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件を2025-04-16に公開中

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