3F49
 
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1KN6
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3CO0
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3BGO
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1ZXH
 | | G311 mutant protein | | 分子名称: | Immunoglobulin G binding protein G | | 著者 | He, Y, Yeh, D.C, Alexander, P, Bryan, P.N, Orban, J. | | 登録日 | 2005-06-08 | | 公開日 | 2005-11-08 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution NMR structures of IgG binding domains with artificially evolved high levels of sequence identity but different folds.
Biochemistry, 44, 2005
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1ZXG
 | | Solution structure of A219 | | 分子名称: | Immunoglobulin G binding protein A | | 著者 | He, Y, Yeh, D.C, Alexander, P, Bryan, P.N, Orban, J. | | 登録日 | 2005-06-08 | | 公開日 | 2005-11-08 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution NMR structures of IgG binding domains with artificially evolved high levels of sequence identity but different folds.
Biochemistry, 44, 2005
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6UAI
 | | Imidazole-triggered RAS-specific subtilisin SUBT_BACAM complexed with YSAM peptide | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Toth, E.A, Bryan, P.N, Orban, J. | | 登録日 | 2019-09-10 | | 公開日 | 2020-09-16 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Engineering subtilisin proteases that specifically degrade active RAS.
Commun Biol, 4, 2021
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6UAO
 | | Imidazole-triggered RAS-specific subtilisin SUBT_BACAM complexed with the peptide EEYSAM | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Peptide EEYSAM, ... | | 著者 | Toth, E.A, Bryan, P.N, Orban, J. | | 登録日 | 2019-09-11 | | 公開日 | 2020-09-16 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | Engineering subtilisin proteases that specifically degrade active RAS.
Commun Biol, 4, 2021
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6UBE
 | | Azide-triggered subtilisin SUBT_BACAM complexed with the peptide LFRAL | | 分子名称: | AZIDE ION, GLYCEROL, Peptide LFRAL, ... | | 著者 | Toth, E.A, Bryan, P.N, Orban, J, Gallagher, D.T, Custer, G. | | 登録日 | 2019-09-11 | | 公開日 | 2020-09-16 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Engineering subtilisin proteases that specifically degrade active RAS.
Commun Biol, 4, 2021
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6U9L
 | | Imidazole-triggered RAS-specific subtilisin SUBT_BACAM | | 分子名称: | GLYCEROL, POTASSIUM ION, SUBTILISIN BPN', ... | | 著者 | Toth, E.A, Bryan, P.N, Orban, J. | | 登録日 | 2019-09-09 | | 公開日 | 2020-09-16 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Engineering subtilisin proteases that specifically degrade active RAS.
Commun Biol, 4, 2021
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3CNQ
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1AU9
 | | SUBTILISIN BPN' MUTANT 8324 IN CITRATE | | 分子名称: | CALCIUM ION, ISOPROPYL ALCOHOL, SUBTILISIN BPN', ... | | 著者 | Whitlow, M, Howard, A.J, Wood, J.F. | | 登録日 | 1997-09-12 | | 公開日 | 1997-12-31 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Large increases in general stability for subtilisin BPN' through incremental changes in the free energy of unfolding.
Biochemistry, 28, 1989
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1AK9
 | | SUBTILISIN MUTANT 8321 | | 分子名称: | CALCIUM ION, ISOPROPYL ALCOHOL, SODIUM ION, ... | | 著者 | Whitlow, M, Howard, A.J, Wood, J.F. | | 登録日 | 1997-05-30 | | 公開日 | 1997-11-12 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Large increases in general stability for subtilisin BPN' through incremental changes in the free energy of unfolding.
Biochemistry, 28, 1989
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1S01
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1A2Q
 | | SUBTILISIN BPN' MUTANT 7186 | | 分子名称: | ACETONE, CALCIUM ION, SUBTILISIN BPN' | | 著者 | Gilliland, G.L, Whitlow, M, Howard, A.J. | | 登録日 | 1998-01-08 | | 公開日 | 1998-04-29 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Large increases in general stability for subtilisin BPN' through incremental changes in the free energy of unfolding.
Biochemistry, 28, 1989
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1AQN
 | | SUBTILISIN MUTANT 8324 | | 分子名称: | CALCIUM ION, ISOPROPYL ALCOHOL, SUBTILISIN 8324, ... | | 著者 | Whitlow, M, Howard, A.J, Wood, J.F. | | 登録日 | 1997-07-31 | | 公開日 | 1998-01-14 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Large increases in general stabilityfor subtilisin BPN' through incremental changes in the free energy of unfolding
To be published
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7MN2
 | | Rules for designing protein fold switches and their implications for the folding code | | 分子名称: | Sb2 | | 著者 | He, Y, Chen, Y, Ruan, B, Choi, J, Chen, Y, Motabar, D, Solomon, T, Simmerman, R, Kauffman, T, Gallagher, T, Bryan, P, Orban, J. | | 登録日 | 2021-04-30 | | 公開日 | 2022-05-18 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Design and characterization of a protein fold switching network.
Nat Commun, 14, 2023
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7MP7
 | | Rules for designing protein fold switches and their implications for the folding code | | 分子名称: | Sb3 | | 著者 | He, Y, Chen, Y, Ruan, B, Choi, J, Chen, Y, Motabar, D, Solomon, T, Simmerman, R, Kauffman, T, Gallagher, T, Bryan, P, Orban, J. | | 登録日 | 2021-05-04 | | 公開日 | 2022-05-18 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Design and characterization of a protein fold switching network.
Nat Commun, 14, 2023
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7MN1
 | | Rules for designing protein fold switches and their implications for the folding code | | 分子名称: | Sa1 | | 著者 | He, Y, Chen, Y, Ruan, B, Choi, J, Chen, Y, Motabar, D, Solomon, T, Simmerman, R, Kauffman, T, Gallagher, T, Bryan, P, Orban, J. | | 登録日 | 2021-04-30 | | 公開日 | 2022-05-18 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Design and characterization of a protein fold switching network.
Nat Commun, 14, 2023
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7MQ4
 | | Rules for designing protein fold switches and their implications for the folding code | | 分子名称: | Sb1 | | 著者 | He, Y, Chen, Y, Ruan, B, Choi, J, Chen, Y, Motabar, D, Solomon, T, Simmerman, R, Kauffman, T, Gallagher, T, Bryan, P, Orban, J. | | 登録日 | 2021-05-05 | | 公開日 | 2022-05-18 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Design and characterization of a protein fold switching network.
Nat Commun, 14, 2023
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2KDM
 | | NMR structures of GA95 and GB95, two designed proteins with 95% sequence identity but different folds and functions | | 分子名称: | DESIGNED PROTEIN | | 著者 | He, Y, Alexander, P, Chen, Y, Bryan, P, Orban, J. | | 登録日 | 2009-01-12 | | 公開日 | 2009-12-29 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | From the Cover: A minimal sequence code for switching protein structure and function.
Proc.Natl.Acad.Sci.USA, 106, 2009
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2LHD
 | | GB98 solution structure | | 分子名称: | GB98 | | 著者 | He, Y, Chen, Y, Alexander, P, Bryan, P, Orban, J. | | 登録日 | 2011-08-08 | | 公開日 | 2012-02-29 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Mutational tipping points for switching protein folds and functions.
Structure, 20, 2012
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2LU1
 | | pfsub2 solution NMR structure | | 分子名称: | Subtilase | | 著者 | He, Y, Chen, Y, Ruan, B, O'Brochta, D, Bryan, P, Orban, J. | | 登録日 | 2012-06-06 | | 公開日 | 2012-10-03 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution NMR structure of a sheddase inhibitor prodomain from the malarial parasite Plasmodium falciparum.
Proteins, 80, 2012
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2JWS
 | | Solution NMR structures of two designed proteins with 88% sequence identity but different fold and function | | 分子名称: | Ga88 | | 著者 | He, Y, Chen, Y, Alexander, P, Bryan, P, Orban, J. | | 登録日 | 2007-10-24 | | 公開日 | 2008-09-09 | | 最終更新日 | 2024-05-08 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR structures of two designed proteins with high sequence identity but different fold and function
Proc.Natl.Acad.Sci.Usa, 105, 2008
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2KDL
 | | NMR structures of GA95 and GB95, two designed proteins with 95% sequence identity but different folds and functions | | 分子名称: | designed protein | | 著者 | He, Y, Alexander, P, Chen, Y, Bryan, P, Orban, J. | | 登録日 | 2009-01-12 | | 公開日 | 2009-12-29 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A minimal sequence code for switching protein structure and function.
Proc.Natl.Acad.Sci.USA, 106, 2009
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