3F49
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1KN6
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![BU of 1kn6 by Molmil](/molmil-images/mine/1kn6) | |
3CO0
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![BU of 3co0 by Molmil](/molmil-images/mine/3co0) | |
3BGO
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1ZXH
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![BU of 1zxh by Molmil](/molmil-images/mine/1zxh) | G311 mutant protein | 分子名称: | Immunoglobulin G binding protein G | 著者 | He, Y, Yeh, D.C, Alexander, P, Bryan, P.N, Orban, J. | 登録日 | 2005-06-08 | 公開日 | 2005-11-08 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR structures of IgG binding domains with artificially evolved high levels of sequence identity but different folds. Biochemistry, 44, 2005
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1ZXG
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![BU of 1zxg by Molmil](/molmil-images/mine/1zxg) | Solution structure of A219 | 分子名称: | Immunoglobulin G binding protein A | 著者 | He, Y, Yeh, D.C, Alexander, P, Bryan, P.N, Orban, J. | 登録日 | 2005-06-08 | 公開日 | 2005-11-08 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR structures of IgG binding domains with artificially evolved high levels of sequence identity but different folds. Biochemistry, 44, 2005
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6UAI
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![BU of 6uai by Molmil](/molmil-images/mine/6uai) | Imidazole-triggered RAS-specific subtilisin SUBT_BACAM complexed with YSAM peptide | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Toth, E.A, Bryan, P.N, Orban, J. | 登録日 | 2019-09-10 | 公開日 | 2020-09-16 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Engineering subtilisin proteases that specifically degrade active RAS. Commun Biol, 4, 2021
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6UAO
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![BU of 6uao by Molmil](/molmil-images/mine/6uao) | Imidazole-triggered RAS-specific subtilisin SUBT_BACAM complexed with the peptide EEYSAM | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Peptide EEYSAM, ... | 著者 | Toth, E.A, Bryan, P.N, Orban, J. | 登録日 | 2019-09-11 | 公開日 | 2020-09-16 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | Engineering subtilisin proteases that specifically degrade active RAS. Commun Biol, 4, 2021
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6UBE
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![BU of 6ube by Molmil](/molmil-images/mine/6ube) | Azide-triggered subtilisin SUBT_BACAM complexed with the peptide LFRAL | 分子名称: | AZIDE ION, GLYCEROL, Peptide LFRAL, ... | 著者 | Toth, E.A, Bryan, P.N, Orban, J, Gallagher, D.T, Custer, G. | 登録日 | 2019-09-11 | 公開日 | 2020-09-16 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Engineering subtilisin proteases that specifically degrade active RAS. Commun Biol, 4, 2021
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6U9L
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![BU of 6u9l by Molmil](/molmil-images/mine/6u9l) | Imidazole-triggered RAS-specific subtilisin SUBT_BACAM | 分子名称: | GLYCEROL, POTASSIUM ION, SUBTILISIN BPN', ... | 著者 | Toth, E.A, Bryan, P.N, Orban, J. | 登録日 | 2019-09-09 | 公開日 | 2020-09-16 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Engineering subtilisin proteases that specifically degrade active RAS. Commun Biol, 4, 2021
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3CNQ
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1AU9
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![BU of 1au9 by Molmil](/molmil-images/mine/1au9) | SUBTILISIN BPN' MUTANT 8324 IN CITRATE | 分子名称: | CALCIUM ION, ISOPROPYL ALCOHOL, SUBTILISIN BPN', ... | 著者 | Whitlow, M, Howard, A.J, Wood, J.F. | 登録日 | 1997-09-12 | 公開日 | 1997-12-31 | 最終更新日 | 2021-11-03 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Large increases in general stability for subtilisin BPN' through incremental changes in the free energy of unfolding. Biochemistry, 28, 1989
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1AK9
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![BU of 1ak9 by Molmil](/molmil-images/mine/1ak9) | SUBTILISIN MUTANT 8321 | 分子名称: | CALCIUM ION, ISOPROPYL ALCOHOL, SODIUM ION, ... | 著者 | Whitlow, M, Howard, A.J, Wood, J.F. | 登録日 | 1997-05-30 | 公開日 | 1997-11-12 | 最終更新日 | 2021-11-03 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Large increases in general stability for subtilisin BPN' through incremental changes in the free energy of unfolding. Biochemistry, 28, 1989
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1S01
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1A2Q
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![BU of 1a2q by Molmil](/molmil-images/mine/1a2q) | SUBTILISIN BPN' MUTANT 7186 | 分子名称: | ACETONE, CALCIUM ION, SUBTILISIN BPN' | 著者 | Gilliland, G.L, Whitlow, M, Howard, A.J. | 登録日 | 1998-01-08 | 公開日 | 1998-04-29 | 最終更新日 | 2021-11-03 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Large increases in general stability for subtilisin BPN' through incremental changes in the free energy of unfolding. Biochemistry, 28, 1989
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1AQN
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![BU of 1aqn by Molmil](/molmil-images/mine/1aqn) | SUBTILISIN MUTANT 8324 | 分子名称: | CALCIUM ION, ISOPROPYL ALCOHOL, SUBTILISIN 8324, ... | 著者 | Whitlow, M, Howard, A.J, Wood, J.F. | 登録日 | 1997-07-31 | 公開日 | 1998-01-14 | 最終更新日 | 2021-11-03 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Large increases in general stabilityfor subtilisin BPN' through incremental changes in the free energy of unfolding To be published
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7MN2
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![BU of 7mn2 by Molmil](/molmil-images/mine/7mn2) | Rules for designing protein fold switches and their implications for the folding code | 分子名称: | Sb2 | 著者 | He, Y, Chen, Y, Ruan, B, Choi, J, Chen, Y, Motabar, D, Solomon, T, Simmerman, R, Kauffman, T, Gallagher, T, Bryan, P, Orban, J. | 登録日 | 2021-04-30 | 公開日 | 2022-05-18 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Design and characterization of a protein fold switching network. Nat Commun, 14, 2023
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7MP7
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![BU of 7mp7 by Molmil](/molmil-images/mine/7mp7) | Rules for designing protein fold switches and their implications for the folding code | 分子名称: | Sb3 | 著者 | He, Y, Chen, Y, Ruan, B, Choi, J, Chen, Y, Motabar, D, Solomon, T, Simmerman, R, Kauffman, T, Gallagher, T, Bryan, P, Orban, J. | 登録日 | 2021-05-04 | 公開日 | 2022-05-18 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Design and characterization of a protein fold switching network. Nat Commun, 14, 2023
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7MN1
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![BU of 7mn1 by Molmil](/molmil-images/mine/7mn1) | Rules for designing protein fold switches and their implications for the folding code | 分子名称: | Sa1 | 著者 | He, Y, Chen, Y, Ruan, B, Choi, J, Chen, Y, Motabar, D, Solomon, T, Simmerman, R, Kauffman, T, Gallagher, T, Bryan, P, Orban, J. | 登録日 | 2021-04-30 | 公開日 | 2022-05-18 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Design and characterization of a protein fold switching network. Nat Commun, 14, 2023
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7MQ4
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![BU of 7mq4 by Molmil](/molmil-images/mine/7mq4) | Rules for designing protein fold switches and their implications for the folding code | 分子名称: | Sb1 | 著者 | He, Y, Chen, Y, Ruan, B, Choi, J, Chen, Y, Motabar, D, Solomon, T, Simmerman, R, Kauffman, T, Gallagher, T, Bryan, P, Orban, J. | 登録日 | 2021-05-05 | 公開日 | 2022-05-18 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Design and characterization of a protein fold switching network. Nat Commun, 14, 2023
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2KDM
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![BU of 2kdm by Molmil](/molmil-images/mine/2kdm) | NMR structures of GA95 and GB95, two designed proteins with 95% sequence identity but different folds and functions | 分子名称: | DESIGNED PROTEIN | 著者 | He, Y, Alexander, P, Chen, Y, Bryan, P, Orban, J. | 登録日 | 2009-01-12 | 公開日 | 2009-12-29 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | From the Cover: A minimal sequence code for switching protein structure and function. Proc.Natl.Acad.Sci.USA, 106, 2009
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2LHD
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![BU of 2lhd by Molmil](/molmil-images/mine/2lhd) | GB98 solution structure | 分子名称: | GB98 | 著者 | He, Y, Chen, Y, Alexander, P, Bryan, P, Orban, J. | 登録日 | 2011-08-08 | 公開日 | 2012-02-29 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Mutational tipping points for switching protein folds and functions. Structure, 20, 2012
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2LU1
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![BU of 2lu1 by Molmil](/molmil-images/mine/2lu1) | pfsub2 solution NMR structure | 分子名称: | Subtilase | 著者 | He, Y, Chen, Y, Ruan, B, O'Brochta, D, Bryan, P, Orban, J. | 登録日 | 2012-06-06 | 公開日 | 2012-10-03 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR structure of a sheddase inhibitor prodomain from the malarial parasite Plasmodium falciparum. Proteins, 80, 2012
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2JWS
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![BU of 2jws by Molmil](/molmil-images/mine/2jws) | Solution NMR structures of two designed proteins with 88% sequence identity but different fold and function | 分子名称: | Ga88 | 著者 | He, Y, Chen, Y, Alexander, P, Bryan, P, Orban, J. | 登録日 | 2007-10-24 | 公開日 | 2008-09-09 | 最終更新日 | 2024-05-08 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structures of two designed proteins with high sequence identity but different fold and function Proc.Natl.Acad.Sci.Usa, 105, 2008
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2KDL
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![BU of 2kdl by Molmil](/molmil-images/mine/2kdl) | NMR structures of GA95 and GB95, two designed proteins with 95% sequence identity but different folds and functions | 分子名称: | designed protein | 著者 | He, Y, Alexander, P, Chen, Y, Bryan, P, Orban, J. | 登録日 | 2009-01-12 | 公開日 | 2009-12-29 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | A minimal sequence code for switching protein structure and function. Proc.Natl.Acad.Sci.USA, 106, 2009
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