8QZQ
| Single particle cryo-EM co-structure of E. coli AcrB with bound BDM91531 inhibitor | 分子名称: | Multidrug efflux pump subunit AcrB, [(2~{R})-1-[[(2~{R})-2,3-bis(oxidanyl)propoxy]-oxidanyl-phosphoryl]oxy-3-undecanoyloxy-propan-2-yl] tricosanoate, [3-(3-chloranyl-2-piperazin-1-yl-quinolin-6-yl)phenyl]methanamine | 著者 | Boernsen, C, Mueller, R.T, Pos, K.M, Frangakis, A.S. | 登録日 | 2023-10-29 | 公開日 | 2024-11-06 | 実験手法 | ELECTRON MICROSCOPY (3.23 Å) | 主引用文献 | Single particle cryo-EM co-structure of E. coli AcrB with bound BDM91531 inhibitor at 3.23 A resolution To be published
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8QZL
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8QZT
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8P1I
| Single particle cryo-EM co-structure of Klebsiella pneumoniae AcrB with the BDM91288 efflux pump inhibitor at 2.97 Angstrom resolution | 分子名称: | 1,2-DIOCTANOYL-SN-GLYCERO-3-[PHOSPHO-RAC-(1-GLYCEROL), 3-chloranyl-2,6-di(piperazin-4-ium-1-yl)quinoline, Efflux pump membrane transporter, ... | 著者 | Boernsen, C, Mueller, R.T, Pos, K.M, Frangakis, A.S. | 登録日 | 2023-05-12 | 公開日 | 2024-01-17 | 最終更新日 | 2024-01-31 | 実験手法 | ELECTRON MICROSCOPY (2.97 Å) | 主引用文献 | Pyridylpiperazine efflux pump inhibitor boosts in vivo antibiotic efficacy against K. pneumoniae. Embo Mol Med, 16, 2024
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