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8QZQ
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BU of 8qzq by Molmil
Single particle cryo-EM co-structure of E. coli AcrB with bound BDM91531 inhibitor
分子名称: Multidrug efflux pump subunit AcrB, [(2~{R})-1-[[(2~{R})-2,3-bis(oxidanyl)propoxy]-oxidanyl-phosphoryl]oxy-3-undecanoyloxy-propan-2-yl] tricosanoate, [3-(3-chloranyl-2-piperazin-1-yl-quinolin-6-yl)phenyl]methanamine
著者Boernsen, C, Mueller, R.T, Pos, K.M, Frangakis, A.S.
登録日2023-10-29
公開日2024-11-06
実験手法ELECTRON MICROSCOPY (3.23 Å)
主引用文献Single particle cryo-EM co-structure of E. coli AcrB with bound BDM91531 inhibitor at 3.23 A resolution
To be published
8QZL
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BU of 8qzl by Molmil
Single particle cryo-EM co-structure of Klebsiella pneumoniae AcrB with the BDM91288 efflux pump inhibitor at 3.42 Angstrom resolution
分子名称: 3-chloranyl-2,6-di(piperazin-4-ium-1-yl)quinoline, Efflux pump membrane transporter
著者Boernsen, C, Mueller, R.T, Pos, K.M, Frangakis, A.S.
登録日2023-10-27
公開日2024-11-06
実験手法ELECTRON MICROSCOPY (3.42 Å)
主引用文献Single particle cryo-EM co-structure of Klebsiella pneumoniae AcrB with the BDM91288 efflux pump inhibitor at 3.42 Angstrom resolution
To be published
8QZT
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BU of 8qzt by Molmil
Single particle cryo-EM co-structure of E. coli AcrB with bound BDM91531 inhibitor at 3.52 A resolution
分子名称: Multidrug efflux pump subunit AcrB, [3-(3-chloranyl-2-piperazin-1-yl-quinolin-6-yl)phenyl]methanamine
著者Boernsen, C, Mueller, R.T, Pos, K.M, Frangakis, A.S.
登録日2023-10-29
公開日2024-11-06
実験手法ELECTRON MICROSCOPY (3.52 Å)
主引用文献Single particle cryo-EM co-structure of E. coli AcrB with bound BDM91531 inhibitor at 3.52 A resolution
To be published
8P1I
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BU of 8p1i by Molmil
Single particle cryo-EM co-structure of Klebsiella pneumoniae AcrB with the BDM91288 efflux pump inhibitor at 2.97 Angstrom resolution
分子名称: 1,2-DIOCTANOYL-SN-GLYCERO-3-[PHOSPHO-RAC-(1-GLYCEROL), 3-chloranyl-2,6-di(piperazin-4-ium-1-yl)quinoline, Efflux pump membrane transporter, ...
著者Boernsen, C, Mueller, R.T, Pos, K.M, Frangakis, A.S.
登録日2023-05-12
公開日2024-01-17
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (2.97 Å)
主引用文献Pyridylpiperazine efflux pump inhibitor boosts in vivo antibiotic efficacy against K. pneumoniae.
Embo Mol Med, 16, 2024

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件を2024-11-06に公開中

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