8QZL

Single particle cryo-EM co-structure of Klebsiella pneumoniae AcrB with the BDM91288 efflux pump inhibitor at 3.42 Angstrom resolution

Summary for 8QZL

• Entry DOI: 10.2210/pdb8qzl/pdb
• Related: 8P1I
• EMDB information: 17350 18777
• Descriptor: Efflux pump membrane transporter, 3-chloranyl-2,6-di(piperazin-4-ium-1-yl)quinoline (2 entities in total)
• Functional Keywords: efflux pump inhibitor, transmembrane binding, antibiotic resistance, transport protein
• Biological source: Klebsiella pneumoniae subsp. pneumoniae DSM 30104 = JCM 1662 = NBRC 14940
• Total number of polymer chains: 3
• Total formula weight: 344137.55

Authors

Boernsen, C.,Mueller, R.T.,Pos, K.M.,Frangakis, A.S. (deposition date: 2023-10-27, release date: 2024-11-06)

• Primary citation: Boernsen, C.,Mueller, R.T.; Single particle cryo-EM co-structure of Klebsiella pneumoniae AcrB with the BDM91288 efflux pump inhibitor at 3.42 Angstrom resolution; To be published,

Experimental method

ELECTRON MICROSCOPY (3.42 Å)