8QZL

Single particle cryo-EM co-structure of Klebsiella pneumoniae AcrB with the BDM91288 efflux pump inhibitor at 3.42 Angstrom resolution

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	Efflux pump membrane transporter	polymer	1056	114489.9	3	UniProt (J2LW81) Pfam (PF00873) UniProt (by SIFTS) (W1DJX9)	Klebsiella pneumoniae subsp. pneumoniae DSM 30104 = JCM 1662 = NBRC 14940
2	D, E (A, C)	3-chloranyl-2,6-di(piperazin-4-ium-1-yl)quinoline	non-polymer		333.9	2	Chemie (WQW)

Sequence modifications

A, B, C: 1 - 1048 (UniProt: J2LW81)

PDB	External Database	Details
Leu 1049	-	expression tag
Glu 1050	-	expression tag
His 1051	-	expression tag
His 1052	-	expression tag
His 1053	-	expression tag
His 1054	-	expression tag
His 1055	-	expression tag
His 1056	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	343469.8
Non-Polymers*	Number of molecules	2
	Total formula weight	667.7
All*	Total formula weight	344137.6

*Water molecules are not included.