8QZT

Single particle cryo-EM co-structure of E. coli AcrB with bound BDM91531 inhibitor at 3.52 A resolution

Summary for 8QZT

• Entry DOI: 10.2210/pdb8qzt/pdb
• Related: 8QZQ
• EMDB information: 18780 18782
• Descriptor: Multidrug efflux pump subunit AcrB, [3-(3-chloranyl-2-piperazin-1-yl-quinolin-6-yl)phenyl]methanamine (2 entities in total)
• Functional Keywords: efflux pump inhibitor, transmembrane binding, antibiotic resistance, transport protein
• Biological source: Escherichia coli K-12
• Total number of polymer chains: 3
• Total formula weight: 341701.26

Authors

Boernsen, C.,Mueller, R.T.,Pos, K.M.,Frangakis, A.S. (deposition date: 2023-10-29, release date: 2024-11-06)

• Primary citation: Boernsen, C.,Mueller, R.T.; Single particle cryo-EM co-structure of E. coli AcrB with bound BDM91531 inhibitor at 3.52 A resolution; To be published,

Experimental method

ELECTRON MICROSCOPY (3.52 Å)