5KWN
 
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1AJJ
 | | LDL RECEPTOR LIGAND-BINDING MODULE 5, CALCIUM-COORDINATING | | 分子名称: | CALCIUM ION, LOW-DENSITY LIPOPROTEIN RECEPTOR, SULFATE ION | | 著者 | Fass, D, Blacklow, S.C, Kim, P.S, Berger, J.M. | | 登録日 | 1997-05-04 | | 公開日 | 1997-07-07 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Molecular basis of familial hypercholesterolaemia from structure of LDL receptor module.
Nature, 388, 1997
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8G2Y
 | | Cryo-EM structure of ADGRF1 coupled to miniGs/q | | 分子名称: | Adhesion G-protein-coupled receptor F1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Jones, D, Rawson, S, Blacklow, S. | | 登録日 | 2023-02-06 | | 公開日 | 2023-05-10 | | 実験手法 | ELECTRON MICROSCOPY (3.44 Å) | | 主引用文献 | Tethered agonist activated ADGRF1 structure and signalling analysis reveal basis for G protein coupling.
Nat Commun, 14, 2023
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3V79
 | | Structure of human Notch1 transcription complex including CSL, RAM, ANK, and MAML-1 on HES-1 promoter DNA sequence | | 分子名称: | DNA 5'-D(*GP*TP*TP*AP*CP*TP*GP*TP*GP*GP*GP*AP*AP*AP*GP*AP*AP*A)-3', DNA 5'-D(*TP*TP*TP*CP*TP*TP*TP*CP*CP*CP*AP*CP*AP*GP*TP*AP*AP*C)-3', Mastermind-like protein 1, ... | | 著者 | Nam, Y, Sliz, P, Blacklow, S. | | 登録日 | 2011-12-20 | | 公開日 | 2012-02-15 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.85 Å) | | 主引用文献 | Conformational Locking upon Cooperative Assembly of Notch Transcription Complexes.
Structure, 20, 2012
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4WIV
 | | Crystal Structure of the first bromodomain of human BRD4 in complex with a novel inhibitor UMB32 (N-TERT-BUTYL-2-[4-(3,5-DIMETHYL-1,2-OXAZOL-4-YL) PHENYL]IMIDAZO[1,2-A]PYRAZIN-3-AMINE) | | 分子名称: | 1,2-ETHANEDIOL, Bromodomain-containing protein 4, GLYCEROL, ... | | 著者 | Xu, X, Blacklow, S. | | 登録日 | 2014-09-26 | | 公開日 | 2014-10-29 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | | 主引用文献 | Biased multicomponent reactions to develop novel bromodomain inhibitors.
J.Med.Chem., 57, 2014
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4WVL
 | | Structure-Guided DOT1L Probe Optimization by Label-Free Ligand Displacement | | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Histone-lysine N-methyltransferase, ... | | 著者 | Xu, X, Dhe-Paganon, S, Blacklow, S. | | 登録日 | 2014-11-06 | | 公開日 | 2014-12-03 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | | 主引用文献 | Structure-Guided DOT1L Probe Optimization by Label-Free Ligand Displacement.
Acs Chem.Biol., 10, 2015
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