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4TX0
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BU of 4tx0 by Molmil
The Fk1 domain of FKBP51 in complex with (1S,5S,6R)-10-[(3,5-dichlorophenyl)sulfonyl]-5-(2-methoxyethoxy)-3-(2-methoxyethyl)-3,10-diazabicyclo[4.3.1]decan-2-one
分子名称: (1S,5S,6R)-10-[(3,5-dichlorophenyl)sulfonyl]-5-(2-methoxyethoxy)-3-(2-methoxyethyl)-3,10-diazabicyclo[4.3.1]decan-2-one, Peptidyl-prolyl cis-trans isomerase FKBP5
著者Bischoff, M, Sippel, C, Bracher, A, Hausch, F.
登録日2014-07-02
公開日2014-10-15
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.03 Å)
主引用文献Stereoselective Construction of the 5-Hydroxy Diazabicyclo[4.3.1]decane-2-one Scaffold, a Privileged Motif for FK506-Binding Proteins.
Org.Lett., 16, 2014
4NZL
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Extracellular proteins of Staphylococcus aureus inhibit the neutrophil serine proteases
分子名称: Neutrophil elastase, Uncharacterized protein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose
著者Stapels, D.A.C, von Koeckritz-Blickwede, M, Ramyar, K.X, Bischoff, M, Milder, F, Ruyken, M, Scheepmaker, L, McWhorter, W.J, Herrmann, M, van Kessel, K.P.M, Geisbrecht, B.V, Rooijakkers, S.H.M.
登録日2013-12-12
公開日2014-08-20
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Staphylococcus aureus secretes a unique class of neutrophil serine protease inhibitors.
Proc.Natl.Acad.Sci.USA, 111, 2014
7A5V
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BU of 7a5v by Molmil
CryoEM structure of a human gamma-aminobutyric acid receptor, the GABA(A)R-beta3 homopentamer, in complex with histamine and megabody Mb25 in lipid nanodisc
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
著者Nakane, T, Kotecha, A, Sente, A, Yamashita, K, McMullan, G, Masiulis, S, Brown, P.M.G.E, Grigoras, I.T, Malinauskaite, L, Malinauskas, T, Miehling, J, Yu, L, Karia, D, Pechnikova, E.V, de Jong, E, Keizer, J, Bischoff, M, McCormack, J, Tiemeijer, P, Hardwick, S.W, Chirgadze, D.Y, Murshudov, G, Aricescu, A.R, Scheres, S.H.W.
登録日2020-08-22
公開日2020-11-18
最終更新日2020-11-25
実験手法ELECTRON MICROSCOPY (1.7 Å)
主引用文献Single-particle cryo-EM at atomic resolution.
Nature, 587, 2020
7A4M
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BU of 7a4m by Molmil
Cryo-EM structure of mouse heavy-chain apoferritin at 1.22 A
分子名称: FE (III) ION, Ferritin heavy chain, ZINC ION
著者Nakane, T, Kotecha, A, Sente, A, Yamashita, K, McMullan, G, Masiulis, S, Brown, P.M.G.E, Grigoras, I.T, Malinauskaite, L, Malinauskas, T, Miehling, J, Yu, L, Karia, D, Pechnikova, E.V, de Jong, E, Keizer, J, Bischoff, M, McCormack, J, Tiemeijer, P, Hardwick, S.W, Chirgadze, D.Y, Murshudov, G, Aricescu, A.R, Scheres, S.H.W.
登録日2020-08-20
公開日2020-10-28
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (1.22 Å)
主引用文献Single-particle cryo-EM at atomic resolution.
Nature, 587, 2020
8ACK
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Structure of Pseudomonas aeruginosa aminopeptidase, PaAP
分子名称: CACODYLATE ION, Keratinase KP1, PCP, ...
著者Harding, C.J, Czekster, C.M.
登録日2022-07-05
公開日2023-07-12
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.784 Å)
主引用文献An anti-biofilm cyclic peptide targets a secreted aminopeptidase from P. aeruginosa.
Nat.Chem.Biol., 19, 2023
8ACR
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BU of 8acr by Molmil
Structure of Pseudomonas aeruginosa aminopeptidase, PaAP
分子名称: Keratinase KP1, SODIUM ION, ZINC ION
著者Harding, C.J, Czekster, C.M.
登録日2022-07-06
公開日2023-07-12
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献An anti-biofilm cyclic peptide targets a secreted aminopeptidase from P. aeruginosa.
Nat.Chem.Biol., 19, 2023
8ACG
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BU of 8acg by Molmil
Structure of Pseudomonas aeruginosa aminopeptidase, PaAP_T E340A mutant
分子名称: Keratinase KP1, MAGNESIUM ION, ZINC ION
著者Harding, C.J, Czekster, C.M.
登録日2022-07-05
公開日2023-07-12
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.84 Å)
主引用文献An anti-biofilm cyclic peptide targets a secreted aminopeptidase from P. aeruginosa.
Nat.Chem.Biol., 19, 2023
8AC7
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BU of 8ac7 by Molmil
Structure of Pseudomonas aeruginosa aminopeptidase, PaAP
分子名称: ACETATE ION, ISOPROPYL ALCOHOL, Keratinase KP1, ...
著者Harding, C.J, Czekster, C.M.
登録日2022-07-05
公開日2023-07-12
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献An anti-biofilm cyclic peptide targets a secreted aminopeptidase from P. aeruginosa.
Nat.Chem.Biol., 19, 2023
8AC9
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BU of 8ac9 by Molmil
Structure of Pseudomonas aeruginosa aminopeptidase, PaAP_T
分子名称: Keratinase KP1, ZINC ION
著者Harding, C.J, Czekster, C.M.
登録日2022-07-05
公開日2023-07-12
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.351 Å)
主引用文献An anti-biofilm cyclic peptide targets a secreted aminopeptidase from P. aeruginosa.
Nat.Chem.Biol., 19, 2023
6VJS
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BU of 6vjs by Molmil
Escherichia coli RNA polymerase and ureidothiophene-2-carboxylic acid complex
分子名称: 3-{[benzyl(ethyl)carbamoyl]amino}-5-(4-phenoxyphenyl)thiophene-2-carboxylic acid, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Murakami, K.S, Molodtsov, V.
登録日2020-01-17
公開日2020-10-07
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (4.02 Å)
主引用文献Evaluation of Bacterial RNA Polymerase Inhibitors in a Staphylococcus aureus -Based Wound Infection Model in SKH1 Mice.
Acs Infect Dis., 6, 2020

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件を2024-07-24に公開中

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