3QL0
 
 | | Crystal structure of N23PP/S148A mutant of E. coli dihydrofolate reductase | | 分子名称: | Dihydrofolate reductase, FOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | 著者 | Bhabha, G, Ekiert, D.C, Wright, P.E, Wilson, I.A. | | 登録日 | 2011-02-02 | | 公開日 | 2011-04-20 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | A dynamic knockout reveals that conformational fluctuations influence the chemical step of enzyme catalysis.
Science, 332, 2011
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3QL3
 | | Re-refined coordinates for PDB entry 1RX2 | | 分子名称: | Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ... | | 著者 | Bhabha, G, Ekiert, D.C, Wright, P.E, Wilson, I.A. | | 登録日 | 2011-02-02 | | 公開日 | 2011-04-27 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | A dynamic knockout reveals that conformational fluctuations influence the chemical step of enzyme catalysis.
Science, 332, 2011
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4M6K
 | | Crystal structure of human dihydrofolate reductase (DHFR) bound to NADP+ and folate | | 分子名称: | Dihydrofolate reductase, FOLIC ACID, GLYCEROL, ... | | 著者 | Bhabha, G, Ekiert, D.C, Wright, P.E, Wilson, I.A. | | 登録日 | 2013-08-09 | | 公開日 | 2013-09-25 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.396 Å) | | 主引用文献 | Divergent evolution of protein conformational dynamics in dihydrofolate reductase.
Nat.Struct.Mol.Biol., 20, 2013
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4M6L
 | | Crystal structure of human dihydrofolate reductase (DHFR) bound to NADP+ and 5,10-dideazatetrahydrofolic acid | | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Dihydrofolate reductase, N-(4-{2-[(6S)-2-amino-4-oxo-1,4,5,6,7,8-hexahydropyrido[2,3-d]pyrimidin-6-yl]ethyl}benzoyl)-L-glutamic acid, ... | | 著者 | Bhabha, G, Ekiert, D.C, Wright, P.E, Wilson, I.A. | | 登録日 | 2013-08-09 | | 公開日 | 2013-09-25 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Divergent evolution of protein conformational dynamics in dihydrofolate reductase.
Nat.Struct.Mol.Biol., 20, 2013
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4M6J
 | | Crystal structure of human dihydrofolate reductase (DHFR) bound to NADPH | | 分子名称: | Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Bhabha, G, Ekiert, D.C, Wright, P.E, Wilson, I.A. | | 登録日 | 2013-08-09 | | 公開日 | 2013-09-25 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.201 Å) | | 主引用文献 | Divergent evolution of protein conformational dynamics in dihydrofolate reductase.
Nat.Struct.Mol.Biol., 20, 2013
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4W8F
 | | Crystal structure of the dynein motor domain in the AMPPNP-bound state | | 分子名称: | Dynein heavy chain lysozyme chimera, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | 著者 | Cheng, H.-C, Bhabha, G, Zhang, N, Vale, R.D. | | 登録日 | 2014-08-24 | | 公開日 | 2014-11-12 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (3.541 Å) | | 主引用文献 | Allosteric communication in the Dynein motor domain.
Cell, 159, 2014
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4PEK
 | | Crystal structure of a computationally designed retro-aldolase, RA114.3 | | 分子名称: | Retro-aldolase | | 著者 | Bhabha, G, Zhang, X, Liu, Y, Ekiert, D.C. | | 登録日 | 2014-04-23 | | 公開日 | 2015-04-08 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | De novo-designed enzymes as small-molecule-regulated fluorescence imaging tags and fluorescent reporters.
J.Am.Chem.Soc., 136, 2014
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4PEJ
 | | Crystal structure of a computationally designed retro-aldolase, RA110.4 (Cys free) | | 分子名称: | Retro-aldolase | | 著者 | Bhabha, G, Zhang, X, Liu, Y, Ekiert, D.C. | | 登録日 | 2014-04-23 | | 公開日 | 2015-04-08 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | De novo-designed enzymes as small-molecule-regulated fluorescence imaging tags and fluorescent reporters.
J.Am.Chem.Soc., 136, 2014
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5UWB
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5UWA
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5UVN
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5UW2
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5UW8
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4OU1
 | | Crystal structure of a computationally designed retro-aldolase covalently bound to folding probe 1 [(6-methoxynaphthalen-2-yl)(oxiran-2-yl)methanol] | | 分子名称: | (1S,2S)-1-(6-methoxynaphthalen-2-yl)propane-1,2-diol, BENZOIC ACID, PHOSPHATE ION, ... | | 著者 | Bhabha, G, Zhang, X, Ekiert, D.C. | | 登録日 | 2014-02-14 | | 公開日 | 2014-03-05 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Small molecule probes to quantify the functional fraction of a specific protein in a cell with minimal folding equilibrium shifts.
Proc.Natl.Acad.Sci.USA, 111, 2014
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5CWF
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5CWQ
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5CWO
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5CWN
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5CWJ
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5CWP
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5CWL
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5CWG
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5CWB
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5CWK
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5CWC
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