1AFS
 
 | | RECOMBINANT RAT LIVER 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE (3-ALPHA-HSD) COMPLEXED WITH NADP AND TESTOSTERONE | | 分子名称: | 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, TESTOSTERONE | | 著者 | Bennett, M.J, Albert, R.H, Jez, J.M, Ma, H, Penning, T.M, Lewis, M. | | 登録日 | 1997-03-13 | | 公開日 | 1997-10-08 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Steroid recognition and regulation of hormone action: crystal structure of testosterone and NADP+ bound to 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase.
Structure, 5, 1997
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1MDT
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1DDT
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1LWI
 | | 3-ALPHA-HYDROXYSTEROID/DIHYDRODIOL DEHYDROGENASE FROM RATTUS NORVEGICUS | | 分子名称: | 3-ALPHA-HYDROXYSTEROID/DIHYDRODIOL DEHYDROGENASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Bennett, M.J, Schlegel, B.P, Jez, J.M, Penning, T.M, Lewis, M. | | 登録日 | 1996-02-24 | | 公開日 | 1996-12-07 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structure of 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase complexed with NADP+.
Biochemistry, 35, 1996
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1DE4
 | | HEMOCHROMATOSIS PROTEIN HFE COMPLEXED WITH TRANSFERRIN RECEPTOR | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BETA-2-MICROGLOBULIN, CALCIUM ION, ... | | 著者 | Bennett, M.J, Lebron, J.A, Bjorkman, P.J. | | 登録日 | 1999-11-12 | | 公開日 | 2000-01-19 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure of the hereditary haemochromatosis protein HFE complexed with transferrin receptor.
Nature, 403, 2000
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1Z8L
 | | Crystal structure of prostate-specific membrane antigen, a tumor marker and peptidase | | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Davis, M.I, Bennett, M.J, Thomas, L.M, Bjorkman, P.J. | | 登録日 | 2005-03-30 | | 公開日 | 2005-04-19 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Crystal structure of prostate-specific membrane antigen, a tumor marker and peptidase
Proc.Natl.Acad.Sci.USA, 102, 2005
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1A6Z
 | | HFE (HUMAN) HEMOCHROMATOSIS PROTEIN | | 分子名称: | BETA-2-MICROGLOBULIN, HFE | | 著者 | Lebron, J.A, Bennett, M.J, Vaughn, D.E, Chirino, A.J, Snow, P.M, Mintier, G.A, Feder, J.N, Bjorkman, P.J. | | 登録日 | 1998-03-04 | | 公開日 | 1999-03-23 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structure of the hemochromatosis protein HFE and characterization of its interaction with transferrin receptor.
Cell(Cambridge,Mass.), 93, 1998
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2GSG
 | | Crystal structure of the Fv fragment of a monoclonal antibody specific for poly-glutamine | | 分子名称: | SULFATE ION, monoclonal antibody heavy chain, monoclonal antibody light chain | | 著者 | Li, P, Huey-Tubman, K.E, West Jr, A.P, Bennett, M.J, Bjorkman, P.J. | | 登録日 | 2006-04-26 | | 公開日 | 2007-04-24 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The structure of a polyQ-anti-polyQ complex reveals binding according to a linear lattice model.
Nat.Struct.Mol.Biol., 14, 2007
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6CKS
 | | Crystal Structure of BRD4 with QC4956 | | 分子名称: | 4-[5-(ethylsulfonyl)-2-methoxyphenyl]-2-methyl-6-(1-methyl-1H-pyrazol-4-yl)isoquinolin-1(2H)-one, Bromodomain-containing protein 4 | | 著者 | Hosfield, D.J. | | 登録日 | 2018-02-28 | | 公開日 | 2018-05-02 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | Design, synthesis and biological evaluation of novel 4-phenylisoquinolinone BET bromodomain inhibitors.
Bioorg. Med. Chem. Lett., 28, 2018
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6CKR
 | | Crystal Structure of BRD4 with QC4956 | | 分子名称: | Bromodomain-containing protein 4, N-{3-[2-methyl-6-(1-methyl-1H-pyrazol-4-yl)-1-oxo-1,2-dihydroisoquinolin-4-yl]phenyl}methanesulfonamide | | 著者 | Hosfield, D.J. | | 登録日 | 2018-02-28 | | 公開日 | 2018-05-02 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | | 主引用文献 | Design, synthesis and biological evaluation of novel 4-phenylisoquinolinone BET bromodomain inhibitors.
Bioorg. Med. Chem. Lett., 28, 2018
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6DHL
 | | Bovine glutamate dehydrogenase complexed with epicatechin-3-gallate (ECG) | | 分子名称: | (2R,3S)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate, Glutamate dehydrogenase 1, mitochondrial | | 著者 | Smith, T.J. | | 登録日 | 2018-05-20 | | 公開日 | 2018-07-25 | | 実験手法 | X-RAY DIFFRACTION (3.624 Å) | | 主引用文献 | Green tea polyphenols control dysregulated glutamate dehydrogenase in transgenic mice by hijacking the ADP activation site.
J. Biol. Chem., 286, 2011
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1SGK
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1TOX
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1DTP
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1A80
 | | Native 2,5-DIKETO-D-GLUCONIC acid reductase a from CORYNBACTERIUM SP. complexed with nadph | | 分子名称: | 2,5-DIKETO-D-GLUCONIC ACID REDUCTASE A, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Khurana, S, Powers, D.B, Anderson, S, Blaber, M. | | 登録日 | 1998-03-31 | | 公開日 | 1999-03-30 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of 2,5-diketo-D-gluconic acid reductase A complexed with NADPH at 2.1-A resolution.
Proc.Natl.Acad.Sci.USA, 95, 1998
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