6ZLH
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![BU of 6zlh by Molmil](/molmil-images/mine/6zlh) | the structure of glutamate transporter homologue GltTk in complex with the photo switchable compound (trans) | 分子名称: | (2~{S},3~{S})-2-azanyl-3-[[4-[2-(4-methoxyphenyl)hydrazinyl]phenyl]methoxy]butanedioic acid, DECYL-BETA-D-MALTOPYRANOSIDE, DI(HYDROXYETHYL)ETHER, ... | 著者 | Arkhipova, V, Slotboom, D.J, Guskov, A. | 登録日 | 2020-06-30 | 公開日 | 2021-01-27 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural Aspects of Photopharmacology: Insight into the Binding of Photoswitchable and Photocaged Inhibitors to the Glutamate Transporter Homologue. J.Am.Chem.Soc., 143, 2021
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6R7R
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![BU of 6r7r by Molmil](/molmil-images/mine/6r7r) | Crystal structure of the glutamate transporter homologue GltTk in complex with D-aspartate | 分子名称: | D-ASPARTIC ACID, DECYL-BETA-D-MALTOPYRANOSIDE, DI(HYDROXYETHYL)ETHER, ... | 著者 | Arkhipova, V, Guskov, A, Slotboom, D.J. | 登録日 | 2019-03-29 | 公開日 | 2019-04-17 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Binding and transport of D-aspartate by the glutamate transporter homolog Glt Tk . Elife, 8, 2019
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6XWR
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6XWP
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![BU of 6xwp by Molmil](/molmil-images/mine/6xwp) | |
6XWO
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![BU of 6xwo by Molmil](/molmil-images/mine/6xwo) | |
6XWN
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6XWQ
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6ZL4
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![BU of 6zl4 by Molmil](/molmil-images/mine/6zl4) | the structure of glutamate transporter homologue GltTk in complex with the photo switchable compound (cis) | 分子名称: | (2~{S},3~{S})-2-azanyl-3-[[4-[2-(4-methoxyphenyl)hydrazinyl]phenyl]methoxy]butanedioic acid, DECYL-BETA-D-MALTOPYRANOSIDE, DI(HYDROXYETHYL)ETHER, ... | 著者 | Arkhipova, V, Slotboom, D.J, Guskov, A. | 登録日 | 2020-06-30 | 公開日 | 2021-01-27 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural Aspects of Photopharmacology: Insight into the Binding of Photoswitchable and Photocaged Inhibitors to the Glutamate Transporter Homologue. J.Am.Chem.Soc., 143, 2021
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6ZGB
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![BU of 6zgb by Molmil](/molmil-images/mine/6zgb) | glutamate transporter homologue Glttk in complex with a photo cage compound | 分子名称: | (2~{S},3~{S})-2-azanyl-3-[(2-nitrophenyl)methoxy]butanedioic acid, DI(HYDROXYETHYL)ETHER, Proton/glutamate symporter, ... | 著者 | Arkhipova, V, Slotboom, D.J, Guskov, A. | 登録日 | 2020-06-18 | 公開日 | 2021-01-27 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural Aspects of Photopharmacology: Insight into the Binding of Photoswitchable and Photocaged Inhibitors to the Glutamate Transporter Homologue. J.Am.Chem.Soc., 143, 2021
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7NGH
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![BU of 7ngh by Molmil](/molmil-images/mine/7ngh) | Structure of glutamate transporter homologue in complex with Sybody | 分子名称: | ASPARTIC ACID, Proton/glutamate symporter, SDF family, ... | 著者 | Arkhipova, V, Slotboom, D.J, Guskov, A. | 登録日 | 2021-02-09 | 公開日 | 2021-09-15 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Kinetic mechanism of Na + -coupled aspartate transport catalyzed by Glt Tk . Commun Biol, 4, 2021
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4XQ3
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![BU of 4xq3 by Molmil](/molmil-images/mine/4xq3) | Crystal structure of Sso-SmAP2 | 分子名称: | Like-Sm ribonucleoprotein core | 著者 | Bezerra, G.A, Martens, B, Kreuter, M.J, Grishkovskaya, I, Manica, M, Arkhipova, V, Blasi, U, Djinovic-Carugo, K. | 登録日 | 2015-01-18 | 公開日 | 2015-04-29 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | The Heptameric SmAP1 and SmAP2 Proteins of the Crenarchaeon Sulfolobus Solfataricus Bind to Common and Distinct RNA Targets. Life, 5, 2015
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7ZV2
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![BU of 7zv2 by Molmil](/molmil-images/mine/7zv2) | HUMAN PRMT5:MEP50 Crystal Structure With MTA and Fragment Bound | 分子名称: | 5'-DEOXY-5'-METHYLTHIOADENOSINE, GLYCEROL, Methylosome protein 50, ... | 著者 | Ahmad, M.U, Koelmel, W, Arkhipova, V, Lawson, J.D, Smith, C.R, Gunn, R.J. | 登録日 | 2022-05-13 | 公開日 | 2022-10-19 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Fragment optimization and elaboration strategies - the discovery of two lead series of PRMT5/MTA inhibitors from five fragment hits. Rsc Med Chem, 13, 2022
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7ZVL
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![BU of 7zvl by Molmil](/molmil-images/mine/7zvl) | HUMAN PRMT5:MEP50 Crystal Structure With MTA and Fragment Bound | 分子名称: | 5'-DEOXY-5'-METHYLTHIOADENOSINE, CHLORIDE ION, GLYCEROL, ... | 著者 | Ahmad, M.U, Koelmel, W, Arkhipova, V, Lawson, J.D, Smith, C.R, Gunn, R.J. | 登録日 | 2022-05-16 | 公開日 | 2022-10-19 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | Fragment optimization and elaboration strategies - the discovery of two lead series of PRMT5/MTA inhibitors from five fragment hits. Rsc Med Chem, 13, 2022
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7ZUU
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![BU of 7zuu by Molmil](/molmil-images/mine/7zuu) | HUMAN PRMT5:MEP50 Crystal Structure With MTA and Fragment Bound | 分子名称: | 5'-DEOXY-5'-METHYLTHIOADENOSINE, GLYCEROL, Methylosome protein 50, ... | 著者 | Ahmad, M.U, Koelmel, W, Arkhipova, V, Lawson, J.D, Smith, C.R, Gunn, R.J. | 登録日 | 2022-05-13 | 公開日 | 2022-10-19 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Fragment optimization and elaboration strategies - the discovery of two lead series of PRMT5/MTA inhibitors from five fragment hits. Rsc Med Chem, 13, 2022
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7ZUQ
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![BU of 7zuq by Molmil](/molmil-images/mine/7zuq) | HUMAN PRMT5:MEP50 Crystal Structure With MTA and Fragment Bound | 分子名称: | 5'-DEOXY-5'-METHYLTHIOADENOSINE, GLYCEROL, Methylosome protein 50, ... | 著者 | Ahmad, M.U, Koelmel, W, Arkhipova, V, Lawson, J.D, Smith, C.R, Gunn, R.J. | 登録日 | 2022-05-13 | 公開日 | 2022-10-19 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | 主引用文献 | Fragment optimization and elaboration strategies - the discovery of two lead series of PRMT5/MTA inhibitors from five fragment hits. Rsc Med Chem, 13, 2022
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7ZUP
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![BU of 7zup by Molmil](/molmil-images/mine/7zup) | Human PRMT5:MEP50 structure with Fragment (Example 18) and MTA Bound | 分子名称: | 3-ethylimidazo[4,5-b]pyridin-2-amine, 5'-DEOXY-5'-METHYLTHIOADENOSINE, GLYCEROL, ... | 著者 | Ahmad, M.U, Koelmel, W, Arkhipova, V, Lawson, J.D, Smith, C.R, Gunn, R.J. | 登録日 | 2022-05-12 | 公開日 | 2022-10-19 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Fragment optimization and elaboration strategies - the discovery of two lead series of PRMT5/MTA inhibitors from five fragment hits. Rsc Med Chem, 13, 2022
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7ZUY
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![BU of 7zuy by Molmil](/molmil-images/mine/7zuy) | HUMAN PRMT5:MEP50 Crystal Structure With MTA and Fragment Bound | 分子名称: | 5'-DEOXY-5'-METHYLTHIOADENOSINE, GLYCEROL, Methylosome protein 50, ... | 著者 | Ahmad, M.U, Koelmel, W, Arkhipova, V, Lawson, J.D, Smith, C.R, Gunn, R.J. | 登録日 | 2022-05-13 | 公開日 | 2022-10-19 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Fragment optimization and elaboration strategies - the discovery of two lead series of PRMT5/MTA inhibitors from five fragment hits. Rsc Med Chem, 13, 2022
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7ZVU
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![BU of 7zvu by Molmil](/molmil-images/mine/7zvu) | HUMAN PRMT5:MEP50 Crystal Structure With MTA and Fragment Bound | 分子名称: | 5'-DEOXY-5'-METHYLTHIOADENOSINE, GLYCEROL, Methylosome protein 50, ... | 著者 | Ahmad, M.U, Koelmel, W, Arkhipova, V, Lawson, J.D, Smith, C.R, Gunn, R.J. | 登録日 | 2022-05-17 | 公開日 | 2022-10-19 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Fragment optimization and elaboration strategies - the discovery of two lead series of PRMT5/MTA inhibitors from five fragment hits. Rsc Med Chem, 13, 2022
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4M0L
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![BU of 4m0l by Molmil](/molmil-images/mine/4m0l) | Gamma subunit of the translation initiation factor 2 from Sulfolobus solfataricus complexed with GDP | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... | 著者 | Nikonov, O.S, Stolboushkina, E.A, Arkhipova, V.I, Gabdulkhakov, A.G, Nikulin, A.D, Lazopulo, A.M, Lazopulo, S.M, Garber, M.B, Nikonov, S.V. | 登録日 | 2013-08-01 | 公開日 | 2013-08-28 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Conformational transitions in the gamma subunit of the archaeal translation initiation factor 2. Acta Crystallogr.,Sect.D, 70, 2014
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4M53
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![BU of 4m53 by Molmil](/molmil-images/mine/4m53) | Gamma subunit of the translation initiation factor 2 from Sulfolobus solfataricus in complex with GDPCP | 分子名称: | BETA-MERCAPTOETHANOL, FORMIC ACID, MAGNESIUM ION, ... | 著者 | Nikonov, O.S, Stolboushkina, E.A, Arkhipova, V.I, Lazopulo, A.M, Lazopulo, S.M, Gabdulkhakov, A.G, Nikulin, A.D, Garber, M.B, Nikonov, S.V. | 登録日 | 2013-08-07 | 公開日 | 2013-08-28 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Conformational transitions in the gamma subunit of the archaeal translation initiation factor 2. Acta Crystallogr.,Sect.D, 70, 2014
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4M4S
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![BU of 4m4s by Molmil](/molmil-images/mine/4m4s) | Gamma subunit of the translation initiation factor 2 from Sulfolobus solfataricus in complex with GDP and formate ion mimic aIF2gamma*GDP*Pi complex (a formate ion substitutes for Pi) | 分子名称: | FORMIC ACID, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Nikonov, O.S, Stolboushkina, E.A, Arkhipova, V.I, Gabdulkhakov, A.G, Nikulin, A.D, Garber, M.B, Nikonov, S.V. | 登録日 | 2013-08-07 | 公開日 | 2014-03-12 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.251 Å) | 主引用文献 | Conformational transitions in the gamma subunit of the archaeal translation initiation factor 2. Acta Crystallogr.,Sect.D, 70, 2014
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4M2L
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![BU of 4m2l by Molmil](/molmil-images/mine/4m2l) | Gamma subunit of the translation initiation factor 2 from Sulfolobus solfataricus in nucleotide-free form | 分子名称: | 1,2-ETHANEDIOL, PHOSPHATE ION, SULFATE ION, ... | 著者 | Nikonov, O.S, Stolboushkina, E.A, Arkhipova, V.I, Gabdulkhakov, A.G, Nikulin, A.D, Garber, M.B, Nikonov, S.V. | 登録日 | 2013-08-05 | 公開日 | 2014-03-12 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.149 Å) | 主引用文献 | Conformational transitions in the gamma subunit of the archaeal translation initiation factor 2. Acta Crystallogr.,Sect.D, 70, 2014
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5MYJ
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![BU of 5myj by Molmil](/molmil-images/mine/5myj) | Structure of 70S ribosome from Lactococcus lactis | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Franken, L.E, Oostergetel, G.T, Pijning, T, Puri, P, Boekema, E.J, Poolman, B, Guskov, A. | 登録日 | 2017-01-26 | 公開日 | 2017-10-11 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (5.6 Å) | 主引用文献 | A general mechanism of ribosome dimerization revealed by single-particle cryo-electron microscopy. Nat Commun, 8, 2017
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7UYF
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![BU of 7uyf by Molmil](/molmil-images/mine/7uyf) | Human PRMT5:MEP50 structure with Fragment 4 and MTA Bound | 分子名称: | 4-methyl-1,5-naphthyridin-2-amine, 5'-DEOXY-5'-METHYLTHIOADENOSINE, CHLORIDE ION, ... | 著者 | Gunn, R.J, Lawson, J.D, Smith, C.R. | 登録日 | 2022-05-06 | 公開日 | 2022-10-05 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.82 Å) | 主引用文献 | Fragment optimization and elaboration strategies - the discovery of two lead series of PRMT5/MTA inhibitors from five fragment hits. Rsc Med Chem, 13, 2022
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7UY1
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![BU of 7uy1 by Molmil](/molmil-images/mine/7uy1) | HUMAN PRMT5:MEP50 COMPLEX WITH MTA and Fragment 5 Bound | 分子名称: | 1,2-ETHANEDIOL, 3-methyl-1,5-naphthyridin-2-amine, 5'-DEOXY-5'-METHYLTHIOADENOSINE, ... | 著者 | Gunn, R.J. | 登録日 | 2022-05-06 | 公開日 | 2022-10-05 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.66 Å) | 主引用文献 | Fragment optimization and elaboration strategies - the discovery of two lead series of PRMT5/MTA inhibitors from five fragment hits. Rsc Med Chem, 13, 2022
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