6ZLH

the structure of glutamate transporter homologue GltTk in complex with the photo switchable compound (trans)

Summary for 6ZLH

Entry DOI	10.2210/pdb6zlh/pdb
Related	6ZL4
Descriptor	Proton/glutamate symporter, SDF family, (2~{S},3~{S})-2-azanyl-3-[[4-[2-(4-methoxyphenyl)hydrazinyl]phenyl]methoxy]butanedioic acid, DECYL-BETA-D-MALTOPYRANOSIDE, ... (8 entities in total)
Functional Keywords	glutamate transporter, amino acid transporter, photoisomerization, membrane protein, transport protein
Biological source	Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
Total number of polymer chains	3
Total formula weight	146044.49
Authors	Arkhipova, V.,Slotboom, D.J.,Guskov, A. (deposition date: 2020-06-30, release date: 2021-01-27, Last modification date: 2024-01-31)
Primary citation	Arkhipova, V.,Fu, H.,Hoorens, M.W.H.,Trinco, G.,Lameijer, L.N.,Marin, E.,Feringa, B.L.,Poelarends, G.J.,Szymanski, W.,Slotboom, D.J.,Guskov, A. Structural Aspects of Photopharmacology: Insight into the Binding of Photoswitchable and Photocaged Inhibitors to the Glutamate Transporter Homologue. J.Am.Chem.Soc., 143:1513-1520, 2021 Cited by PubMed: 33449695 DOI: 10.1021/jacs.0c11336 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation