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2PPI
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BU of 2ppi by Molmil
Structure of the BTB (Tramtrack and Bric a brac) domain of human Gigaxonin
分子名称: Gigaxonin
著者Amos, A, Turnbull, A.P, Tickle, J, Keates, T, Bullock, A, Savitsky, P, Burgess-Brown, N, Debreczeni, J.E, Ugochukwu, E, Umeano, C, Pike, A.C.W, Papagrigoriou, E, Sundstrom, M, Arrowsmith, C.H, Weigelt, J, Edwards, A, von Delft, F, Knapp, S, Structural Genomics Consortium (SGC)
登録日2007-04-30
公開日2007-05-08
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of the BTB (Tramtrack and Bric a brac) domain of human Gigaxonin.
To be Published
2BKD
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BU of 2bkd by Molmil
Structure of the N-terminal domain of Fragile X Mental Retardation Protein
分子名称: Fragile X messenger ribonucleoprotein 1
著者Ramos, A, Hollingworth, D, Adinolfi, S, Castets, M, Kelly, G, Frenkiel, T.A, Bardoni, B, Pastore, A.
登録日2005-02-15
公開日2006-01-18
最終更新日2023-02-01
実験手法SOLUTION NMR
主引用文献The structure of the N-terminal domain of the fragile X mental retardation protein: a platform for protein-protein interaction.
Structure, 14, 2006
1EKZ
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BU of 1ekz by Molmil
NMR STRUCTURE OF THE COMPLEX BETWEEN THE THIRD DSRBD FROM DROSOPHILA STAUFEN AND A RNA HAIRPIN
分子名称: MATERNAL EFFECT PROTEIN (STAUFEN), STAUFEN DOUBLE-STRANDED RNA BINDING DOMAIN
著者Ramos, A, Grunert, S, Bycroft, M, St Johnston, D, Varani, G.
登録日2000-03-11
公開日2000-08-21
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献RNA recognition by a Staufen double-stranded RNA-binding domain.
EMBO J., 19, 2000
1IKD
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BU of 1ikd by Molmil
ACCEPTOR STEM, NMR, 30 STRUCTURES
分子名称: TRNA ALA ACCEPTOR STEM
著者Ramos, A, Varani, G.
登録日1996-11-15
公開日1997-04-01
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure of the acceptor stem of Escherichia coli tRNA Ala: role of the G3.U70 base pair in synthetase recognition.
Nucleic Acids Res., 25, 1997
2C47
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BU of 2c47 by Molmil
Structure of casein kinase 1 gamma 2
分子名称: (2R,3R,4S,5R)-2-(4-AMINO-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-(HYDROXYMETHYL)TETRAHYDROFURAN-3,4-DIOL, CASEIN KINASE 1 GAMMA 2 ISOFORM, MAGNESIUM ION
著者Bunkoczi, G, Rellos, P, Das, S, Ugochukwu, E, Fedorov, O, Sobott, F, Eswaran, J, Amos, A, Ball, L, von Delft, F, Bullock, A, Debreczeni, J, Turnbull, A, Sundstrom, M, Weigelt, J, Arrowsmith, C, Edwards, A, Knapp, S.
登録日2005-10-16
公開日2005-11-07
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The Structure of Casein Kinase 1 Gamma 2
To be Published
2BUJ
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BU of 2buj by Molmil
Crystal structure of the human Serine-threonine Kinase 16 in complex with staurosporine
分子名称: CHLORIDE ION, SERINE/THREONINE-PROTEIN KINASE 16, STAUROSPORINE
著者Debreczeni, J.E, Eswaran, J, Bullock, A, Filippakopoulos, P, Kavanagh, K, Amos, A, Fedorov, O, Sobott, F, Ball, L.J, von Delft, F, Arrowsmith, C, Sundstrom, M, Edwards, A, Knapp, S.
登録日2005-06-13
公開日2005-07-05
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structure of the Human Serine-Threonine Kinase 16 in Complex with Staurosporine
To be Published
2IWI
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BU of 2iwi by Molmil
CRYSTAL STRUCTURE OF THE HUMAN PIM2 IN COMPLEX WITH A RUTHENIUM ORGANOMETALLIC LIGAND RU1
分子名称: RUTHENIUM-PYRIDOCARBAZOLE-1, SERINE/THREONINE-PROTEIN KINASE PIM-2
著者Russo, S, Debreczeni, J.E, Amos, A, Bullock, A.N, Fedorov, O, Niesen, F, Sobott, F, Turnbull, A, Pike, A.C.W, Ugochukwu, E, Papagrigoriou, E, Bunkoczi, G, Gorrec, F, Edwards, A, Arrowsmith, C, Weigelt, J, Sundstrom, M, von Delft, F, Knapp, S.
登録日2006-06-30
公開日2006-08-02
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of the PIM2 kinase in complex with an organoruthenium inhibitor.
PLoS ONE, 4, 2009
2UZP
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BU of 2uzp by Molmil
Crystal structure of the C2 domain of human protein kinase C gamma.
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, COBALT (II) ION, ...
著者Pike, A.C.W, Amos, A, Johansson, C, Sobott, F, Savitsky, P, Berridge, G, Fedorov, O, Umeano, C, Gorrec, F, Bunkoczi, G, Debreczeni, J, von Delft, F, Arrowsmith, C.H, Edwards, A, Weigelt, J, Sundstrom, M, Knapp, S.
登録日2007-04-30
公開日2007-05-29
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of C2 Domain of Protein Kinase C Gamma
To be Published
2VD5
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BU of 2vd5 by Molmil
Structure of Human Myotonic Dystrophy Protein Kinase in Complex with the Bisindoylmaleide inhibitor BIM VIII
分子名称: 3-[1-(3-AMINOPROPYL)-1H-INDOL-3-YL]-4-(1-METHYL-1H-INDOL-3-YL)-1H-PYRROLE-2,5-DIONE, DMPK PROTEIN
著者Pike, A.C.W, Amos, A, Elkins, J, Bullock, A, Guo, K, Fedorov, O, Bunkoczi, G, Filippakopoulos, P, Pilka, E.S, Ugochukwu, E, Umeano, C, Niesen, F, Sundstrom, M, Weigelt, J, Edwards, A, Arrowsmith, C.H, von Delft, F, Knapp, S.
登録日2007-09-30
公開日2007-11-06
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of Dystrophia Myotonica Protein Kinase.
Protein Sci., 18, 2009
5CQW
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BU of 5cqw by Molmil
Tetragonal Complex Structure of Protein Kinase CK2 Catalytic Subunit with a Benzotriazole-Based Inhibitor Generated by click-chemistry
分子名称: 4-[4-[2-[4,5,6,7-tetrakis(bromanyl)benzotriazol-2-yl]ethyl]-1,2,3-triazol-1-yl]butan-1-amine, CHLORIDE ION, Casein kinase II subunit alpha, ...
著者Niefind, K, Schnitzler, A, Swider, R, Maslyk, M, Ramos, A.
登録日2015-07-22
公開日2015-09-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Synthesis, Biological Activity and Structural Study of New Benzotriazole-Based Protein Kinase CK2 Inhibitors
Rsc Adv, 5, 2015
5G1N
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BU of 5g1n by Molmil
Aspartate transcarbamoylase domain of human CAD bound to PALA
分子名称: 1,2-ETHANEDIOL, CAD PROTEIN, N-(PHOSPHONACETYL)-L-ASPARTIC ACID
著者Ruiz-Ramos, A, Grande-Garcia, A, Moreno-Morcillo, M.D, Ramon-Maiques, S.
登録日2016-03-29
公開日2016-06-22
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure and Functional Characterization of Human Aspartate Transcarbamoylase, the Target of the Anti-Tumoral Drug Pala.
Structure, 24, 2016
5G1O
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BU of 5g1o by Molmil
Aspartate transcarbamoylase domain of human CAD in apo form
分子名称: 1,2-ETHANEDIOL, CAD protein, GLYCEROL
著者Ruiz-Ramos, A, Grande-Garcia, A, Moreno-Morcillo, M.D, Ramon-Maiques, S.
登録日2016-03-29
公開日2016-06-22
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure and Functional Characterization of Human Aspartate Transcarbamoylase, the Target of the Anti-Tumoral Drug Pala.
Structure, 24, 2016
5G1P
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BU of 5g1p by Molmil
Aspartate transcarbamoylase domain of human CAD bound to carbamoyl phosphate
分子名称: CAD PROTEIN, PHOSPHORIC ACID MONO(FORMAMIDE)ESTER
著者Ruiz-Ramos, A, Grande-Garcia, A, Moreno-Morcillo, M.D, Ramon-Maiques, S.
登録日2016-03-29
公開日2016-06-22
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.19 Å)
主引用文献Structure and Functional Characterization of Human Aspartate Transcarbamoylase, the Target of the Anti-Tumoral Drug Pala.
Structure, 24, 2016
5CQU
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BU of 5cqu by Molmil
Monoclinic Complex Structure of Protein Kinase CK2 Catalytic Subunit with a Benzotriazole-Based Inhibitor Generated by click-chemistry
分子名称: 4-[4-[2-[4,5,6,7-tetrakis(bromanyl)benzotriazol-2-yl]ethyl]-1,2,3-triazol-1-yl]butan-1-amine, Casein kinase II subunit alpha, GLYCEROL, ...
著者Niefind, K, Schnitzler, A, Swider, R, Maslyk, M, Ramos, A.
登録日2015-07-22
公開日2015-09-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Synthesis, Biological Activity and Structural Study of New Benzotriazole-Based Protein Kinase CK2 Inhibitors
Rsc Adv, 5, 2015
8COO
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BU of 8coo by Molmil
Solution structure of Zipcode binding protein 1 (ZBP1) KH3(DD)KH4 domains in complex with N6-Methyladenosine containing RNA
分子名称: Insulin-like growth factor 2 mRNA-binding protein 1, RNA_(5'-R(*(UP*CP*GP*GP*(6MZ)P*CP*U)-3')
著者Nicastro, G, Abis, G, Taylor, I.A, Ramos, A.
登録日2023-02-28
公開日2024-02-07
実験手法SOLUTION NMR
主引用文献Direct m6A recognition by IMP1 underlays an alternative model of target selection for non-canonical methyl-readers.
Nucleic Acids Res., 51, 2023
3COI
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BU of 3coi by Molmil
Crystal structure of p38delta kinase
分子名称: Mitogen-activated protein kinase 13
著者Atwell, S, Burley, S.K, Houle, A, Ramos, A, Sauder, J.M, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2008-03-28
公開日2008-04-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Crystal structure of p38delta kinase.
To be Published
6ES4
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BU of 6es4 by Molmil
A cryptic RNA-binding domain mediates Syncrip recognition and exosomal partitioning of miRNA targets
分子名称: 1,2-ETHANEDIOL, SULFATE ION, Syncrip, ...
著者Hobor, F, Dallmann, A, Ball, N.J, Cicchini, C, Battistelli, C, Ogrodowicz, R.W, Christodoulou, E, Martin, S.R, Castello, A, Tripodi, M, Taylor, I.A, Ramos, A.
登録日2017-10-19
公開日2018-03-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A cryptic RNA-binding domain mediates Syncrip recognition and exosomal partitioning of miRNA targets.
Nat Commun, 9, 2018
2N8M
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BU of 2n8m by Molmil
Zipcode-binding-protein-1 KH3(DD)KH4 domains in complex with the KH4 RNA target
分子名称: Insulin-like growth factor 2 mRNA-binding protein 1, RNA (5'-R(P*UP*CP*GP*GP*AP*CP*U)-3')
著者Nicastro, G, Ramos, A, Candel, A, Hollingworth, D.
登録日2015-10-21
公開日2017-01-25
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Zipcode-binding-protein-1 KH3(DD)KH4 domains in complex with the RNA target UCGGACU
To be Published
6SAI
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BU of 6sai by Molmil
NMR solution structure of Hml-2 C-terminal dimer domain
分子名称: Gag protein
著者Nicastro, G, Taylor, I.A, Ball, N.J, Ramos, A.
登録日2019-07-16
公開日2020-01-15
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural basis for Fullerene geometry in a human endogenous retrovirus capsid.
Nat Commun, 10, 2019
2JVZ
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BU of 2jvz by Molmil
Solution NMR Structure of the Second and Third KH Domains of KSRP
分子名称: Far upstream element-binding protein 2
著者Diaz-Moreno, I, Hollingworth, D, Garcia-Mayoral, M.F, Kelly, G, Cukier, C.D, Ramos, A.
登録日2007-09-28
公開日2009-02-17
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution NMR Structure of the Second and Third KH Domains of KSRP
To be Published, 2007
2N8L
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BU of 2n8l by Molmil
Zipcode-binding-protein-1 KH3KH4(DD) domains in complex with the KH3 RNA target
分子名称: Insulin-like growth factor 2 mRNA-binding protein 1, RNA (5'-R(P*GP*CP*AP*CP*AP*CP*CP*C)-3')
著者Nicastro, G, Candel, A.M, Ramos, A, Hollingworth, D.
登録日2015-10-21
公開日2017-01-25
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Zipcode-binding-protein-1 KH3KH4(DD) domains in complex with the RNA target GCACACCC
To be Published
4B8T
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BU of 4b8t by Molmil
RNA BINDING PROTEIN Solution structure of the third KH domain of KSRP in complex with the G-rich target sequence.
分子名称: 5'-R(*AP*GP*GP*GP*UP)-3', KH-TYPE SPLICING REGULATORY PROTEIN
著者Nicastro, G, Garcia-Mayoral, M.F, Hollingworth, D, Kelly, G, Martin, S.R, Briata, P, Gherzi, R, Ramos, A.
登録日2012-08-30
公開日2012-11-07
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Noncanonical G Recognition Mediates Ksrp Regulation of Let-7 Biogenesis
Nat.Struct.Mol.Biol., 19, 2012
2OPV
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BU of 2opv by Molmil
Solution NMR Structure of the Second Domain of KSRP
分子名称: KHSRP protein
著者Diaz-Moreno, I, Ramos, A, Garcia-Mayoral, M.F, Hollingworth, D.
登録日2007-01-30
公開日2008-02-26
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献The NMR Structures of the N-terminal Domains of KSRP
To be Published
2OPU
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Solution NMR Structure of the First Domain of KSRP
分子名称: KHSRP protein
著者Diaz-Moreno, I, Ramos, A, Garcia-Mayoral, M.F, Hollingworth, D.
登録日2007-01-30
公開日2008-02-26
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Phosphorylation-mediated unfolding of a KH domain regulates KSRP localization via 14-3-3 binding.
Nat.Struct.Mol.Biol., 16, 2009
6QEY
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IMP1 KH1 and KH2 domains create a structural platform with unique RNA recognition and re-modelling properties
分子名称: ACETONITRILE, Insulin-like growth factor 2 mRNA-binding protein 1, PHOSPHATE ION
著者Dagil, R, Ball, N.J, Ogrodowicz, R.W, Purkiss, A.G, Taylor, I.A, Ramos, A.
登録日2019-01-09
公開日2019-03-27
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献IMP1 KH1 and KH2 domains create a structural platform with unique RNA recognition and re-modelling properties.
Nucleic Acids Res., 47, 2019

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