3QYA
 
 | | Crystal structure of a red-emitter mutant of Lampyris turkestanicus luciferase | | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | 著者 | Kheirabadi, M, Gohlke, U, Hossein Khani, S, Heinemann, U, Naderi-Manesh, H. | | 登録日 | 2011-03-03 | | 公開日 | 2012-03-07 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | | 主引用文献 | Crystal structure of native and a mutant of Lampyris turkestanicus luciferase implicate in bioluminescence color shift.
Biochim.Biophys.Acta, 1834, 2013
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5UFR
 | | Structure of RORgt bound to | | 分子名称: | (S)-[4-chloro-2-(dimethylamino)-3-phenylquinolin-6-yl](1-methyl-1H-imidazol-5-yl)(pyridin-4-yl)methanol, Nuclear receptor ROR-gamma | | 著者 | Spurlino, J, Abad, M. | | 登録日 | 2017-01-05 | | 公開日 | 2017-04-05 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.068 Å) | | 主引用文献 | Identification and structure activity relationships of quinoline tertiary alcohol modulators of ROR gamma t.
Bioorg. Med. Chem. Lett., 27, 2017
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5UHI
 | | Structure of RORgt bound to | | 分子名称: | (R)-(4-chloro-2-methoxy-3-{[4-(1H-pyrazol-1-yl)phenyl]methyl}quinolin-6-yl)(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methanol, Nuclear receptor ROR-gamma | | 著者 | Spurlino, J, Abad, M. | | 登録日 | 2017-01-11 | | 公開日 | 2017-04-05 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (3.198 Å) | | 主引用文献 | Identification and structure activity relationships of quinoline tertiary alcohol modulators of ROR gamma t.
Bioorg. Med. Chem. Lett., 27, 2017
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2RDL
 | | Hamster Chymase 2 | | 分子名称: | Chymase 2, METHOXYSUCCINYL-ALA-ALA-PRO-ALA-CHLOROMETHYLKETONE INHIBITOR, SULFATE ION | | 著者 | Spurlino, J, Abad, M, Kervinen, J. | | 登録日 | 2007-09-24 | | 公開日 | 2007-10-30 | | 最終更新日 | 2012-12-12 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural basis for elastolytic substrate specificity in rodent alpha-chymases.
J.Biol.Chem., 283, 2008
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4CA0
 | | Structural Basis for the microtubule binding of the human kinetochore Ska complex | | 分子名称: | SPINDLE AND KINETOCHORE-ASSOCIATED PROTEIN 1 | | 著者 | Abad, M, Medina, B, Santamaria, A, Zou, J, Plasberg-Hill, C, Madhumalar, A, Jayachandran, U, Redli, P.M, Rappsilber, J, Nigg, E.A, Jeyaprakash, A.A. | | 登録日 | 2013-10-04 | | 公開日 | 2014-01-22 | | 実験手法 | X-RAY DIFFRACTION (2.259 Å) | | 主引用文献 | Structural Basis for Microtubule Recognition by the Human Kinetochore Ska Complex.
Nat.Commun., 5, 2014
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4C9Y
 | | Structural Basis for the microtubule binding of the human kinetochore Ska complex | | 分子名称: | SPINDLE AND KINETOCHORE-ASSOCIATED PROTEIN 1 | | 著者 | Abad, M, Medina, B, Santamaria, A, Zou, J, Plasberg-Hill, C, Madhumalar, A, Jayachandran, U, Redli, P.M, Rappsilber, J, Nigg, E.A, Jeyaprakash, A.A. | | 登録日 | 2013-10-04 | | 公開日 | 2014-01-22 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Structural Basis for Microtubule Recognition by the Human Kinetochore Ska Complex.
Nat.Commun., 5, 2014
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4M46
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5W4V
 | | Structure of RORgt bound to a tertiary alcohol | | 分子名称: | (R)-(4-chloro-2-methoxy-3-{[4-(1H-pyrazol-1-yl)phenyl]methyl}quinolin-6-yl)(1-methyl-1H-imidazol-5-yl)[6-(trifluoromethyl)pyridin-3-yl]methanol, Nuclear receptor ROR-gamma | | 著者 | Spurlino, J, Hars, U. | | 登録日 | 2017-06-13 | | 公開日 | 2017-12-27 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | 6-Substituted quinolines as ROR gamma t inverse agonists.
Bioorg. Med. Chem. Lett., 27, 2017
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5W4R
 | | Structure of RORgt bound to a tertiary alcohol | | 分子名称: | 1-{4-[(R)-(4-chloro-2-methoxy-3-{[4-(1H-pyrazol-1-yl)phenyl]methyl}quinolin-6-yl)(hydroxy)(1-methyl-1H-imidazol-5-yl)methyl]piperidin-1-yl}ethan-1-one, Nuclear receptor ROR-gamma | | 著者 | Spurlino, J. | | 登録日 | 2017-06-12 | | 公開日 | 2017-12-27 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (3.002 Å) | | 主引用文献 | 6-Substituted quinolines as ROR gamma t inverse agonists.
Bioorg. Med. Chem. Lett., 27, 2017
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5UFO
 | | Structure of RORgt bound to | | 分子名称: | (S)-{4-chloro-2-methoxy-3-[4-(methylsulfonyl)phenyl]quinolin-6-yl}(1-methyl-1H-imidazol-5-yl)[6-(trifluoromethyl)pyridin-3-yl]methanol, Nuclear receptor ROR-gamma | | 著者 | Spurlino, J. | | 登録日 | 2017-01-05 | | 公開日 | 2017-04-05 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.802 Å) | | 主引用文献 | Identification and structure activity relationships of quinoline tertiary alcohol modulators of ROR gamma t.
Bioorg. Med. Chem. Lett., 27, 2017
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4YMQ
 | | X-ray co-structure of nuclear receptor ROR-GAMMAT + SRC2 peptide with a benzothiadiazole dioxide inverse agonist | | 分子名称: | 4-{3-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)benzyl]-2,2-dioxido-2,1,3-benzothiadiazol-1(3H)-yl}-N-[(2R)-4-hydroxybutan-2-yl]-N-methylbutanamide, GLYCEROL, Nuclear receptor ROR-gamma, ... | | 著者 | li, X. | | 登録日 | 2015-03-07 | | 公開日 | 2015-04-22 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Discovery of 1,3-dihydro-2,1,3-benzothiadiazole 2,2-dioxide analogs as new RORC modulators.
Bioorg.Med.Chem.Lett., 25, 2015
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6URI
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