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5I2P
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BU of 5i2p by Molmil
Resonance assignments and NMR structure determination of tarantula toxin- W7A mutant of mu-TRTX-Pre1a (W6A in native sequence numbering)
分子名称: W7A mu-TRTX-Pre1a Toxin
著者Chin, Y.K.-Y, Wingerd, J.S, Mobli, M, Rash, L.D.
登録日2016-02-09
公開日2017-06-28
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Resonance assignments and NMR structure determination of tarantula toxin- W7A mutant of mu-TRTX-Pre1a
To Be Published
5I1X
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BU of 5i1x by Molmil
Resonance assignments and NMR structure determination of tarantula toxin, F8A mutant of beta-TRTX-Pre1a
分子名称: mu-TRTX-Pre1a toxin
著者Chin, Y.K.-Y, Wingerd, J.S, Mobli, M, Rash, L.D.
登録日2016-02-07
公開日2017-02-08
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Resonance assignments and NMR structure determination of tarantula toxin, mu-TRTX-Pre1a
To Be Published
8UWF
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BU of 8uwf by Molmil
NMR structure of the funnel-web spider toxin Hc3a
分子名称: Pi-Hexatoxin-Hc1b_1
著者Budusan, E, Payne, C.D, Gonzalez, T.I, Clark, R.J, Rosengren, K.J, Rash, L.D, Cristofori-Armstrong, B.
登録日2023-11-06
公開日2024-03-13
最終更新日2024-10-02
実験手法SOLUTION NMR
主引用文献The funnel-web spider venom derived single knot peptide Hc3a modulates acid-sensing ion channel 1a desensitisation.
Biochem Pharmacol, 228, 2024
2MFA
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BU of 2mfa by Molmil
Mambalgin-2
分子名称: Mambalgin-2
著者Schroeder, C.I, Rash, L.D, Vila-Farres, X, Rosengren, K.J, Mobli, M, King, G.F, Alewood, P.F, Craik, D.J, Durek, T.
登録日2013-10-08
公開日2014-01-01
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Chemical synthesis, 3D structure, and ASIC binding site of the toxin mambalgin-2.
Angew.Chem.Int.Ed.Engl., 53, 2014
2MUB
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BU of 2mub by Molmil
Solution structure of the analgesic sea anemone peptide APETx2
分子名称: Toxin APETx2
著者Mobli, M, King, G.F, Rosengren, K.J, Jensen, J.E.
登録日2014-09-07
公開日2014-12-24
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Understanding the Molecular Basis of Toxin Promiscuity: The Analgesic Sea Anemone Peptide APETx2 Interacts with Acid-Sensing Ion Channel 3 and hERG Channels via Overlapping Pharmacophores.
J.Med.Chem., 57, 2014
7JPM
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BU of 7jpm by Molmil
The solution structure of omega-theraphotoxin-Pm1b isolated from King Baboon spider
分子名称: Omega-theraphotoxin-Pm1b
著者Chin, Y.K.-Y, Ziegman, R, Alewood, P.F.
登録日2020-08-09
公開日2021-09-08
最終更新日2023-10-11
実験手法SOLUTION NMR
主引用文献Multitarget nociceptor sensitization by a promiscuous peptide from the venom of the King Baboon spider.
Proc.Natl.Acad.Sci.USA, 119, 2022
5T3M
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Solution structure of a triple mutant of HwTx-IV - a potent blocker of Nav1.7
分子名称: Mu-theraphotoxin-Hs2a
著者Rahnama, S, Sharma, G, Mobli, M.
登録日2016-08-25
公開日2017-09-06
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献The structure, dynamics and selectivity profile of a NaV1.7 potency-optimised huwentoxin-IV variant.
PLoS ONE, 12, 2017
2KNI
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High-resolution solution structure of the ASIC1a blocker PcTX1
分子名称: Psalmotoxin-1
著者King, G.F, Mobli, M, Saez, N.J.
登録日2009-08-25
公開日2010-09-01
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献A dynamic pharmacophore drives the interaction between Psalmotoxin-1 and the putative drug target acid-sensing ion channel 1a.
Mol.Pharmacol., 80, 2011
2N8F
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Chemical shift assignments and structure calculation of spider toxin pi-hexatoxin-Hi1a
分子名称: spider toxin pi-hexatoxin-Hi1a
著者Chin, Y.K.-Y, Pineda, S.S, Mobli, M, King, G.F.
登録日2015-10-13
公開日2016-10-19
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Potent neuroprotection after stroke afforded by a double-knot spider-venom peptide that inhibits acid-sensing ion channel 1a.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017

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件を2024-10-16に公開中

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