3M7N
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3EIK
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3G9A
| Green fluorescent protein bound to minimizer nanobody | 分子名称: | Green fluorescent protein, Minimizer | 著者 | Kirchhofer, A, Helma, J, Schmidthals, K, Frauer, C, Cui, S, Karcher, A, Pellis, M, Muyldermans, S, Delucci, C.C, Cardoso, M.C, Leonhardt, H, Hopfner, K.-P, Rothbauer, U. | 登録日 | 2009-02-13 | 公開日 | 2009-12-08 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.614 Å) | 主引用文献 | Modulation of protein properties in living cells using nanobodies Nat.Struct.Mol.Biol., 17, 2010
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3K1K
| Green fluorescent protein bound to enhancer nanobody | 分子名称: | Enhancer, Green Fluorescent Protein | 著者 | Kirchhofer, A, Helma, J, Schmidthals, K, Frauer, C, Cui, S, Karcher, A, Pellis, M, Muyldermans, S, Delucci, C.C, Cardoso, M.C, Leonhardt, H, Hopfner, K.-P, Rothbauer, U. | 登録日 | 2009-09-28 | 公開日 | 2009-12-08 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Modulation of protein properties in living cells using nanobodies Nat.Struct.Mol.Biol., 17, 2010
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3L51
| Crystal Structure of the Mouse Condensin Hinge Domain | 分子名称: | GLYCEROL, Structural maintenance of chromosomes protein 2, Structural maintenance of chromosomes protein 4 | 著者 | Griese, J.J, Hopfner, K.-P. | 登録日 | 2009-12-21 | 公開日 | 2010-02-16 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.506 Å) | 主引用文献 | Structure and DNA binding activity of the mouse condensin hinge domain highlight common and diverse features of SMC proteins Nucleic Acids Res., 38, 2010
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3M85
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4Y42
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1XEW
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1XBS
| Crystal structure of human dim2: a dim1-like protein | 分子名称: | Dim1-like protein | 著者 | Simeoni, F, Arvai, A, Hopfner, K.-P, Bello, P, Gondeau, C, Heitz, F, Tainer, J, Divita, G. | 登録日 | 2004-08-31 | 公開日 | 2005-08-30 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Biochemical Characterization and Crystal Structure of a Dim1 Family Associated Protein: Dim2 Biochemistry, 44, 2005
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2B2N
| Structure of transcription-repair coupling factor | 分子名称: | O-ACETALDEHYDYL-HEXAETHYLENE GLYCOL, SODIUM ION, SULFATE ION, ... | 著者 | Assenmacher, N, Wenig, K, Lammens, A, Hopfner, K.-P. | 登録日 | 2005-09-19 | 公開日 | 2006-01-24 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural Basis for Transcription-coupled Repair: the N Terminus of Mfd Resembles UvrB with Degenerate ATPase Motifs J.Mol.Biol., 355, 2006
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1XEX
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4WVY
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1II7
| Crystal structure of P. furiosus Mre11 with manganese and dAMP | 分子名称: | 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, MANGANESE (II) ION, Mre11 nuclease, ... | 著者 | Hopfner, K.-P, Karcher, A, Craig, L, Woo, T.T, Carney, J.P, Tainer, J.A. | 登録日 | 2001-04-20 | 公開日 | 2001-05-30 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural biochemistry and interaction architecture of the DNA double-strand break repair Mre11 nuclease and Rad50-ATPase. Cell(Cambridge,Mass.), 105, 2001
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1RFN
| HUMAN COAGULATION FACTOR IXA IN COMPLEX WITH P-AMINO BENZAMIDINE | 分子名称: | CALCIUM ION, P-AMINO BENZAMIDINE, PROTEIN (COAGULATION FACTOR IX), ... | 著者 | Hopfner, K.-P, Lang, A, Karcher, A, Sichler, K, Kopetzki, E, Brandstetter, H, Huber, R, Bode, W, Engh, R.A. | 登録日 | 1999-04-19 | 公開日 | 1999-09-01 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Coagulation factor IXa: the relaxed conformation of Tyr99 blocks substrate binding. Structure Fold.Des., 7, 1999
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1TGO
| THERMOSTABLE B TYPE DNA POLYMERASE FROM THERMOCOCCUS GORGONARIUS | 分子名称: | PROTEIN (THERMOSTABLE B DNA POLYMERASE) | 著者 | Hopfner, K.-P, Eichinger, A, Engh, R.A, Laue, F, Ankenbauer, W, Huber, R, Angerer, B. | 登録日 | 1999-02-23 | 公開日 | 1999-03-22 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of a thermostable type B DNA polymerase from Thermococcus gorgonarius. Proc.Natl.Acad.Sci.USA, 96, 1999
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1II8
| Crystal structure of the P. furiosus Rad50 ATPase domain | 分子名称: | PHOSPHATE ION, Rad50 ABC-ATPase | 著者 | Hopfner, K.-P, Karcher, A, Craig, L, Woo, T.T, Carney, J.P, Tainer, J.A. | 登録日 | 2001-04-20 | 公開日 | 2001-05-30 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (3.02 Å) | 主引用文献 | Structural biochemistry and interaction architecture of the DNA double-strand break repair Mre11 nuclease and Rad50-ATPase. Cell(Cambridge,Mass.), 105, 2001
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3PP4
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3PP3
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6GPG
| Structure of the RIG-I Singleton-Merten syndrome variant C268F | 分子名称: | MAGNESIUM ION, Probable ATP-dependent RNA helicase DDX58, RNA (5'-R(*CP*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*CP*G)-3'), ... | 著者 | Laessig, C, Lammens, K, Hopfner, K.-P. | 登録日 | 2018-06-05 | 公開日 | 2018-08-08 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.894 Å) | 主引用文献 | Unified mechanisms for self-RNA recognition by RIG-I Singleton-Merten syndrome variants. Elife, 7, 2018
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6G7E
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5DA9
| ATP-gamma-S bound Rad50 from Chaetomium thermophilum in complex with the Rad50-binding domain of Mre11 | 分子名称: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Putative double-strand break protein, ... | 著者 | Seifert, F.U, Lammens, K, Stoehr, G, Kessler, B, Hopfner, K.-P. | 登録日 | 2015-08-19 | 公開日 | 2016-03-02 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural mechanism of ATP-dependent DNA binding and DNA end bridging by eukaryotic Rad50. Embo J., 35, 2016
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5DAC
| ATP-gamma-S bound Rad50 from Chaetomium thermophilum in complex with DNA | 分子名称: | 4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE, DNA (5'-D(P*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*C)-3'), DNA (5'-D(P*GP*GP*GP*GP*GP*GP*GP*GP*GP*GP*GP*GP*GP*GP*G)-3'), ... | 著者 | Seifert, F.U, Lammens, K, Stoehr, G, Kessler, B, Hopfner, K.-P. | 登録日 | 2015-08-19 | 公開日 | 2016-03-02 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.503 Å) | 主引用文献 | Structural mechanism of ATP-dependent DNA binding and DNA end bridging by eukaryotic Rad50. Embo J., 35, 2016
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4WK1
| Crystal structure of Staphylococcus aureus PstA in complex with c-di-AMP | 分子名称: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, CALCIUM ION, PstA | 著者 | Mueller, M, Hopfner, K.-P, Witte, G. | 登録日 | 2014-10-01 | 公開日 | 2014-11-26 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | c-di-AMP recognition by Staphylococcus aureus PstA. Febs Lett., 589, 2015
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4WK3
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5N6I
| Crystal structure of mouse cGAS in complex with 39 bp DNA | 分子名称: | Cyclic GMP-AMP synthase, DNA (36-MER), DNA (37-MER), ... | 著者 | Andreeva, L, Kostrewa, D, Hopfner, K.-P. | 登録日 | 2017-02-15 | 公開日 | 2017-09-13 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | cGAS senses long and HMGB/TFAM-bound U-turn DNA by forming protein-DNA ladders. Nature, 549, 2017
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