Search by PDB author

Initial Stuctural Analysis of Leishmania major Threonine Aldolase
分子名称:	THREONINE ALDOLASE, UNKNOWN LIGAND
著者	Hol, W.G.J, Robien, M.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
登録日	2004-03-30
公開日	2004-08-17
最終更新日	2018-01-31
実験手法	X-RAY DIFFRACTION (2.1 Å)
主引用文献	Initial Structural Analysis of Leishmania major Threonine Aldolase To be Published

1RHD

STRUCTURE OF BOVINE LIVER RHODANESE. I. STRUCTURE DETERMINATION AT 2.5 ANGSTROMS RESOLUTION AND A COMPARISON OF THE CONFORMATION AND SEQUENCE OF ITS TWO DOMAINS
分子名称:	RHODANESE
著者	Hol, W.G.J, Ploegman, J.H, Kalk, K.H, Drent, G.
登録日	1977-11-23
公開日	1978-01-16
最終更新日	2017-11-29
実験手法	X-RAY DIFFRACTION (2.5 Å)
主引用文献	Structure of bovine liver rhodanese. I. Structure determination at 2.5 A resolution and a comparison of the conformation and sequence of its two domains. J.Mol.Biol., 123, 1978

6TIM

THE ADAPTABILITY OF THE ACTIVE SITE OF TRYPANOSOMAL TRIOSEPHOSPHATE ISOMERASE AS OBSERVED IN THE CRYSTAL STRUCTURES OF THREE DIFFERENT COMPLEXES
分子名称:	SN-GLYCEROL-3-PHOSPHATE, TRIOSEPHOSPHATE ISOMERASE
著者	Noble, M.E.M, Wierenga, R.K, Hol, W.G.J.
登録日	1991-04-23
公開日	1992-10-15
最終更新日	2024-03-13
実験手法	X-RAY DIFFRACTION (2.2 Å)
主引用文献	The adaptability of the active site of trypanosomal triosephosphate isomerase as observed in the crystal structures of three different complexes. Proteins, 10, 1991

4TIM

CRYSTALLOGRAPHIC AND MOLECULAR MODELING STUDIES ON TRYPANOSOMAL TRIOSEPHOSPHATE ISOMERASE: A CRITICAL ASSESSMENT OF THE PREDICTED AND OBSERVED STRUCTURES OF THE COMPLEX WITH 2-PHOSPHOGLYCERATE
分子名称:	2-PHOSPHOGLYCERIC ACID, TRIOSEPHOSPHATE ISOMERASE
著者	Nobel, M.E.M, Wierenga, R.K, Hol, W.G.J.
登録日	1991-04-11
公開日	1992-10-15
最終更新日	2024-02-28
実験手法	X-RAY DIFFRACTION (2.4 Å)
主引用文献	Crystallographic and molecular modeling studies on trypanosomal triosephosphate isomerase: a critical assessment of the predicted and observed structures of the complex with 2-phosphoglycerate. J.Med.Chem., 34, 1991

1W97

cyto-EpsL: the cytoplasmic domain of EpsL, an inner membrane component of the type II secretion system of Vibrio cholerae
分子名称:	TYPE II SECRETION SYSTEM PROTEIN L
著者	Abendroth, J, Bagdasarian, M, Sansdkvist, M, Hol, W.G.J.
登録日	2004-10-06
公開日	2004-11-30
最終更新日	2019-05-08
実験手法	X-RAY DIFFRACTION (2.7 Å)
主引用文献	The Structure of the Cytoplasmic Domain of Epsl, an Inner Membrane Component of the Type II Secretion System of Vibrio Cholerae: An Unusual Member of the Actin-Like ATPase Superfamily J.Mol.Biol., 344, 2004

6MES

Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor (Chem 1907)
分子名称:	1-[(1H-benzimidazol-2-yl)methyl]-4-[(2,4-dichlorophenyl)methyl]-1,3-dihydro-2H-imidazol-2-one, GLYCEROL, METHIONINE, ...
著者	Barros-Alvarez, X, Hol, W.G.J.
登録日	2018-09-07
公開日	2019-09-18
最終更新日	2024-03-13
実験手法	X-RAY DIFFRACTION (2.9 Å)
主引用文献	Structure-guided discovery of selective methionyl-tRNA synthetase inhibitors with potent activity against Trypanosoma brucei Rsc Med Chem, 2020

5TIM

REFINED 1.83 ANGSTROMS STRUCTURE OF TRYPANOSOMAL TRIOSEPHOSPHATE ISOMERASE, CRYSTALLIZED IN THE PRESENCE OF 2.4 M-AMMONIUM SULPHATE. A COMPARISON WITH THE STRUCTURE OF THE TRYPANOSOMAL TRIOSEPHOSPHATE ISOMERASE-GLYCEROL-3-PHOSPHATE COMPLEX
分子名称:	2,3-DIHYDROXY-1,4-DITHIOBUTANE, SULFATE ION, TRIOSEPHOSPHATE ISOMERASE
著者	Wierenga, R.K, Hol, W.G.J.
登録日	1991-04-23
公開日	1992-10-15
最終更新日	2024-03-06
実験手法	X-RAY DIFFRACTION (1.83 Å)
主引用文献	Refined 1.83 A structure of trypanosomal triosephosphate isomerase crystallized in the presence of 2.4 M-ammonium sulphate. A comparison with the structure of the trypanosomal triosephosphate isomerase-glycerol-3-phosphate complex. J.Mol.Biol., 220, 1991

3BWB

Crystal structure of the apo form of spermidine synthase from Trypanosoma cruzi at 2.5 A resolution
分子名称:	Spermidine synthase
著者	Bosch, J, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
登録日	2008-01-08
公開日	2008-04-01
最終更新日	2011-07-13
実験手法	X-RAY DIFFRACTION (2.5 Å)
主引用文献	Crystal structure of spermidine synthase from Trypanosoma cruzi. To be Published

2PHH

THE COENZYME ANALOGUE ADENOSINE 5-DIPHOSPHORIBOSE DISPLACES FAD IN THE ACTIVE SITE OF P-HYDROXYBENZOATE HYDROXYLASE. AN X-RAY CRYSTALLOGRAPHIC INVESTIGATION
分子名称:	ADENOSINE-5-DIPHOSPHORIBOSE, P-HYDROXYBENZOATE HYDROXYLASE, P-HYDROXYBENZOIC ACID
著者	Van Derlaan, J.M, Drenth, J, Hol, W.G.J.
登録日	1989-06-19
公開日	1990-10-15
最終更新日	2024-02-21
実験手法	X-RAY DIFFRACTION (2.7 Å)
主引用文献	The coenzyme analogue adenosine 5-diphosphoribose displaces FAD in the active site of p-hydroxybenzoate hydroxylase. An x-ray crystallographic investigation. Biochemistry, 28, 1989

1HCY

CRYSTAL STRUCTURE OF HEXAMERIC HAEMOCYANIN FROM PANULIRUS INTERRUPTUS REFINED AT 3.2 ANGSTROMS RESOLUTION
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ARTHROPODAN HEMOCYANIN, COPPER (II) ION
著者	Volbeda, A, Hol, W.G.J.
登録日	1991-05-15
公開日	1994-01-31
最終更新日	2020-07-29
実験手法	X-RAY DIFFRACTION (3.2 Å)
主引用文献	Crystal structure of hexameric haemocyanin from Panulirus interruptus refined at 3.2 A resolution. J.Mol.Biol., 209, 1989

1HC1

CRYSTAL STRUCTURE OF HEXAMERIC HAEMOCYANIN FROM PANULIRUS INTERRUPTUS REFINED AT 3.2 ANGSTROMS RESOLUTION
分子名称:	ARTHROPODAN HEMOCYANIN, COPPER (II) ION
著者	Volbeda, A, Hol, W.G.J.
登録日	1991-05-15
公開日	1994-01-31
最終更新日	2024-06-05
実験手法	X-RAY DIFFRACTION (3.2 Å)
主引用文献	Crystal structure of hexameric haemocyanin from Panulirus interruptus refined at 3.2 A resolution. J.Mol.Biol., 209, 1989

2MAD

THE ACTIVE SITE STRUCTURE OF METHYLAMINE DEHYDROGENASE: HYDRAZINES IDENTIFY C6 AS THE REACTIVE SITE OF THE TRYPTOPHAN DERIVED QUINONE COFACTOR
分子名称:	METHYLAMINE DEHYDROGENASE (HEAVY SUBUNIT), METHYLAMINE DEHYDROGENASE (LIGHT SUBUNIT)
著者	Huizinga, E.G, Vellieux, F.M.D, Hol, W.G.J.
登録日	1992-05-20
公開日	1994-01-31
最終更新日	2024-06-05
実験手法	X-RAY DIFFRACTION (2.25 Å)
主引用文献	Active site structure of methylamine dehydrogenase: hydrazines identify C6 as the reactive site of the tryptophan-derived quinone cofactor. Biochemistry, 31, 1992

1MAF

The Active Site Structure of Methylamine Dehydrogenase: Hydrazines Identify C6 as the Reactive Site of the Tryptophan Derived Quinone Cofactor
分子名称:	METHYLAMINE DEHYDROGENASE (HEAVY SUBUNIT), METHYLAMINE DEHYDROGENASE (LIGHT SUBUNIT), NITROGEN MOLECULE
著者	Huizinga, E.G, Vellieux, F.M.D, Hol, W.G.J.
登録日	1992-05-20
公開日	1994-01-31
最終更新日	2024-06-05
実験手法	X-RAY DIFFRACTION (2.6 Å)
主引用文献	Active site structure of methylamine dehydrogenase: hydrazines identify C6 as the reactive site of the tryptophan-derived quinone cofactor. Biochemistry, 31, 1992

1MAE

The Active Site Structure of Methylamine Dehydrogenase: Hydrazines Identify C6 as the Reactive Site of the Tryptophan Derived Quinone Cofactor
分子名称:	METHYLAMINE DEHYDROGENASE (HEAVY SUBUNIT), METHYLAMINE DEHYDROGENASE (LIGHT SUBUNIT), NITROGEN MOLECULE
著者	Huizinga, E.G, Vellieux, F.M.D, Hol, W.G.J.
登録日	1992-05-20
公開日	1994-01-31
最終更新日	2024-06-05
実験手法	X-RAY DIFFRACTION (2.8 Å)
主引用文献	Active site structure of methylamine dehydrogenase: hydrazines identify C6 as the reactive site of the tryptophan-derived quinone cofactor. Biochemistry, 31, 1992

3BWC

Crystal structure of spermidine synthase from Trypanosoma cruzi in complex with SAM at 2.3 A resolution
分子名称:	BETA-MERCAPTOETHANOL, S-ADENOSYLMETHIONINE, Spermidine synthase
著者	Bosch, J, Arakaki, T.L, Le Trong, I, Merritt, E.A, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
登録日	2008-01-09
公開日	2008-04-01
最終更新日	2023-11-15
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Crystal structure of spermidine synthase from Trypanosoma cruzi. To be Published

5USF

Leishmania donovani tyrosyl-tRNA synthetase in complex with nanobody and inhibitor
分子名称:	5'-O-[N-(L-TYROSYL)SULFAMOYL]ADENOSINE, Immunoglobulin heavy chain variable region, Tyrosyl-tRNA synthetase, ...
著者	Barros-Alvarez, X, Hol, W.G.J.
登録日	2017-02-13
公開日	2017-05-17
最終更新日	2023-10-04
実験手法	X-RAY DIFFRACTION (2.75 Å)
主引用文献	Leishmania donovani tyrosyl-tRNA synthetase structure in complex with a tyrosyl adenylate analog and comparisons with human and protozoan counterparts. Biochimie, 138, 2017

5V49

Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor (Chem 1917)
分子名称:	GLYCEROL, METHIONINE, Methionyl-tRNA synthetase, ...
著者	Barros-Alvarez, X, Hol, W.G.J.
登録日	2017-03-08
公開日	2017-07-26
最終更新日	2024-03-06
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Optimization of a binding fragment targeting the "enlarged methionine pocket" leads to potent Trypanosoma brucei methionyl-tRNA synthetase inhibitors. Bioorg. Med. Chem. Lett., 27, 2017

1MU7

Crystal Structure of a Human Tyrosyl-DNA Phosphodiesterase (Tdp1)-Tungstate Complex
分子名称:	GLYCEROL, TUNGSTATE(VI)ION, Tyrosyl-DNA Phosphodiesterase
著者	Davies, D.R, Interthal, H, Champoux, J.J, Hol, W.G.J.
登録日	2002-09-23
公開日	2003-01-07
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	Insights Into Substrate Binding and Catalytic Mechanism of Human Tyrosyl-DNA Phosphodiesterase (Tdp1) from Vanadate- and Tungstate-Inhibited Structures J.Mol.Biol., 324, 2003

1MU9

Crystal Structure of a Human Tyrosyl-DNA Phosphodiesterase (Tdp1)-Vanadate Complex
分子名称:	GLYCEROL, Tyrosyl-DNA Phosphodiesterase, VANADATE ION
著者	Davies, D.R, Interthal, H, Champoux, J.J, Hol, W.G.J.
登録日	2002-09-23
公開日	2003-01-07
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (2.05 Å)
主引用文献	Insights Into Substrate Binding and Catalytic Mechanism of Human Tyrosyl-DNA Phosphodiesterase (Tdp1) from Vanadate- and Tungstate-Inhibited Structures J.Mol.Biol., 324, 2002

6AX8

Mycobacterium tuberculosis methionyl-tRNA synthetase in complex with methionyl-adenylate
分子名称:	Methionine-tRNA ligase, [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl] (2S)-2-azanyl-4-methylsulfanyl-butanoate
著者	Barros-Alvarez, X, Hol, W.G.J.
登録日	2017-09-06
公開日	2018-04-11
最終更新日	2024-03-13
実験手法	X-RAY DIFFRACTION (2.6 Å)
主引用文献	The crystal structure of the drug target Mycobacterium tuberculosis methionyl-tRNA synthetase in complex with a catalytic intermediate. Acta Crystallogr F Struct Biol Commun, 74, 2018

6BQM

Secreted serine protease VesC from Vibrio cholerae
分子名称:	serine protease VesC
著者	Park, Y.J, Korotkov, K.V, Delarosa, J.R, Turley, S, DiMaio, F, Hol, W.G.J.
登録日	2017-11-28
公開日	2018-11-28
最終更新日	2023-10-04
実験手法	X-RAY DIFFRACTION (2.2 Å)
主引用文献	Suppressor Mutations in Type II Secretion Mutants of Vibrio cholerae: Inactivation of the VesC Protease. Msphere, 5, 2020

6CML

Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor (Chem 2093)
分子名称:	1-[(5-chloro-1H-imidazo[4,5-b]pyridin-2-yl)methyl]-4-[(2-chloro-4-methoxyphenyl)methyl]-3-ethyl-1,3-dihydro-2H-imidazol-2-one, GLYCEROL, METHIONINE, ...
著者	Barros-Alvarez, X, Hol, W.G.J.
登録日	2018-03-05
公開日	2019-03-13
最終更新日	2024-03-13
実験手法	X-RAY DIFFRACTION (2.7 Å)
主引用文献	Structure-guided discovery of selective methionyl-tRNA synthetase inhibitors with potent activity against Trypanosoma brucei Rsc Med Chem, 11, 2020

3TEC

CALCIUM BINDING TO THERMITASE. CRYSTALLOGRAPHIC STUDIES OF THERMITASE AT 0, 5 AND 100 MM CALCIUM
分子名称:	CALCIUM ION, EGLIN C, THERMITASE
著者	Gros, P, Kalk, K.H, Hol, W.G.J.
登録日	1990-10-26
公開日	1992-01-15
最終更新日	2024-02-28
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	Calcium binding to thermitase. Crystallographic studies of thermitase at 0, 5, and 100 mM calcium. J.Biol.Chem., 266, 1991

1PBB

CRYSTAL STRUCTURES OF WILD-TYPE P-HYDROXYBENZOATE HYDROXYLASE COMPLEXED WITH 4-AMINOBENZOATE, 2,4-DIHYDROXYBENZOATE AND 2-HYDROXY-4-AMINOBENZOATE AND OF THE TRY222ALA MUTANT, COMPLEXED WITH 2-HYDROXY-4-AMINOBENZOATE. EVIDENCE FOR A PROTON CHANNEL AND A NEW BINDING MODE OF THE FLAVIN RING
分子名称:	2,4-DIHYDROXYBENZOIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOATE HYDROXYLASE
著者	Schreuder, H.A, Mattevi, A, Hol, W.G.J.
登録日	1994-07-06
公開日	1994-09-30
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (2.5 Å)
主引用文献	Crystal structures of wild-type p-hydroxybenzoate hydroxylase complexed with 4-aminobenzoate,2,4-dihydroxybenzoate, and 2-hydroxy-4-aminobenzoate and of the Tyr222Ala mutant complexed with 2-hydroxy-4-aminobenzoate. Evidence for a proton channel and a new binding mode of the flavin ring Biochemistry, 33, 1994

2SBT

A COMPARISON OF THE THREE-DIMENSIONAL STRUCTURES OF SUBTILISIN BPN AND SUBTILISIN NOVO
分子名称:	ACETONE, SUBTILISIN NOVO
著者	Drenth, J, Hol, W.G.J, Jansonius, J.N, Koekoek, R.
登録日	1976-09-07
公開日	1976-10-06
最終更新日	2024-02-21
実験手法	X-RAY DIFFRACTION (2.8 Å)
主引用文献	A comparison of the three-dimensional structures of subtilisin BPN' and subtilisin novo. Cold Spring Harbor Symp.Quant.Biol., 36, 1972

12 3 4 5 6 7 8 9 10 11 12 13 14 >

全ヒット件数:	332
表示件数:	25
表示順	関連性が高い順