1FTK
 
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1FTM
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2NWW
 | | Crystal structure of GltPh in complex with TBOA | | 分子名称: | (3S)-3-(BENZYLOXY)-L-ASPARTIC ACID, 425aa long hypothetical proton glutamate symport protein | | 著者 | Gouaux, E, Boudker, O, Ryan, R, Yernool, D, Shimamoto, K. | | 登録日 | 2006-11-16 | | 公開日 | 2007-02-27 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Coupling substrate and ion binding to extracellular gate of a sodium-dependent aspartate transporter.
Nature, 445, 2007
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4TLL
 | | Crystal structure of GluN1/GluN2B NMDA receptor, structure 1 | | 分子名称: | 1-AMINOCYCLOPROPANECARBOXYLIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[(1R,2S)-3-(4-benzylpiperidin-1-yl)-1-hydroxy-2-methylpropyl]phenol, ... | | 著者 | Gouaux, E, Lee, C.-H, Lu, W. | | 登録日 | 2014-05-30 | | 公開日 | 2014-07-02 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (3.59 Å) | | 主引用文献 | NMDA receptor structures reveal subunit arrangement and pore architecture.
Nature, 511, 2014
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4TLM
 | | Crystal structure of GluN1/GluN2B NMDA receptor, structure 2 | | 分子名称: | 1-AMINOCYCLOPROPANECARBOXYLIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[(1R,2S)-3-(4-benzylpiperidin-1-yl)-1-hydroxy-2-methylpropyl]phenol, ... | | 著者 | Gouaux, E, Lee, C.-H, Lu, W. | | 登録日 | 2014-05-30 | | 公開日 | 2014-07-02 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (3.77 Å) | | 主引用文献 | NMDA receptor structures reveal subunit arrangement and pore architecture.
Nature, 511, 2014
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6C13
 | | CryoEM structure of mouse PCDH15-4EC-LHFPL5 complex | | 分子名称: | Protocadherin-15, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Gouaux, E, Ge, J, Elferich, J. | | 登録日 | 2018-01-03 | | 公開日 | 2018-08-15 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (11.33 Å) | | 主引用文献 | Structure of mouse protocadherin 15 of the stereocilia tip link in complex with LHFPL5.
Elife, 7, 2018
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2NWX
 | | Crystal structure of GltPh in complex with L-aspartate and sodium ions | | 分子名称: | 425aa long hypothetical proton glutamate symport protein, ASPARTIC ACID, PALMITIC ACID, ... | | 著者 | Gouaux, E, Boudker, O, Ryan, R, Yernool, D, Shimamoto, K. | | 登録日 | 2006-11-16 | | 公開日 | 2007-02-27 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (3.29 Å) | | 主引用文献 | Coupling substrate and ion binding to extracellular gate of a sodium-dependent aspartate transporter.
Nature, 445, 2007
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6C10
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6C14
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2NWL
 | | Crystal structure of GltPh in complex with L-Asp | | 分子名称: | ASPARTIC ACID, PALMITIC ACID, glutamate symport protein | | 著者 | Gouaux, E, Boudker, O, Ryan, R, Yernool, D, Shimamoto, K. | | 登録日 | 2006-11-15 | | 公開日 | 2007-02-27 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.96 Å) | | 主引用文献 | Coupling substrate and ion binding to extracellular gate of a sodium-dependent aspartate transporter.
Nature, 445, 2007
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4XP1
 | | X-ray structure of Drosophila dopamine transporter bound to neurotransmitter dopamine | | 分子名称: | 1,2-ETHANEDIOL, 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Gouaux, E, Penmatsa, A, Wang, K. | | 登録日 | 2015-01-16 | | 公開日 | 2015-05-06 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | | 主引用文献 | Neurotransmitter and psychostimulant recognition by the dopamine transporter.
Nature, 521, 2015
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4XP5
 | | X-ray structure of Drosophila dopamine transporter bound to cocaine analogue-RTI55 | | 分子名称: | 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, Antibody fragment heavy chain-protein, 9D5-heavy chain, ... | | 著者 | Gouaux, E, Penmatsa, A, Wang, K. | | 登録日 | 2015-01-16 | | 公開日 | 2015-05-06 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Neurotransmitter and psychostimulant recognition by the dopamine transporter.
Nature, 521, 2015
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4M48
 | | X-ray structure of dopamine transporter elucidates antidepressant mechanism | | 分子名称: | 9D5 antibody, heavy chain, light chain, ... | | 著者 | Gouaux, E, Penmatsa, A, Wang, K. | | 登録日 | 2013-08-06 | | 公開日 | 2013-09-18 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.955 Å) | | 主引用文献 | X-ray structure of dopamine transporter elucidates antidepressant mechanism.
Nature, 503, 2013
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6NJM
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6NJN
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6NJL
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2I3V
 | | Measurement of conformational changes accompanying desensitization in an ionotropic glutamate receptor: Structure of G725C mutant | | 分子名称: | GLUTAMIC ACID, Glutamate receptor 2, ZINC ION | | 著者 | Armstrong, N, Jasti, J, Beich-Frandsen, M, Gouaux, E. | | 登録日 | 2006-08-21 | | 公開日 | 2006-10-17 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Measurement of Conformational Changes accompanying Desensitization in an Ionotropic Glutamate Receptor.
Cell(Cambridge,Mass.), 127, 2006
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8VBY
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2I3W
 | | Measurement of conformational changes accompanying desensitization in an ionotropic glutamate receptor: Structure of S729C mutant | | 分子名称: | GLUTAMATE RECEPTOR SUBUNIT 2, GLUTAMIC ACID | | 著者 | Armstrong, N, Jasti, J, Beich-Frandsen, M, Gouaux, E. | | 登録日 | 2006-08-21 | | 公開日 | 2006-10-17 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Measurement of Conformational Changes accompanying Desensitization in an Ionotropic Glutamate Receptor.
Cell(Cambridge,Mass.), 127, 2006
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1LB8
 | | Crystal structure of the Non-desensitizing GluR2 ligand binding core mutant (S1S2J-L483Y) in complex with AMPA at 2.3 resolution | | 分子名称: | (S)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID, Glutamate receptor 2 | | 著者 | Sun, Y, Olson, R, Horning, M, Armstrong, N, Mayer, M, Gouaux, E. | | 登録日 | 2002-04-02 | | 公開日 | 2002-06-05 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Mechanism of glutamate receptor desensitization.
Nature, 417, 2002
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8TKP
 | | Structure of the C. elegans TMC-2 complex | | 分子名称: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Clark, S, Jeong, H, Goehring, A, Posert, R, Gouaux, E. | | 登録日 | 2023-07-25 | | 公開日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | The structure of the Caenorhabditis elegans TMC-2 complex suggests roles of lipid-mediated subunit contacts in mechanosensory transduction.
Proc.Natl.Acad.Sci.USA, 121, 2024
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3JAE
 | | Structure of alpha-1 glycine receptor by single particle electron cryo-microscopy, glycine-bound state | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycine receptor subunit alphaZ1 | | 著者 | Du, J, Lu, W, Wu, S.P, Cheng, Y.F, Gouaux, E. | | 登録日 | 2015-06-08 | | 公開日 | 2015-09-09 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Glycine receptor mechanism elucidated by electron cryo-microscopy.
Nature, 526, 2015
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3JAD
 | | Structure of alpha-1 glycine receptor by single particle electron cryo-microscopy, strychnine-bound state | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycine receptor subunit alphaZ1, STRYCHNINE | | 著者 | Du, J, Lu, W, Wu, S.P, Cheng, Y.F, Gouaux, E. | | 登録日 | 2015-06-08 | | 公開日 | 2015-09-09 | | 最終更新日 | 2024-11-06 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Glycine receptor mechanism elucidated by electron cryo-microscopy.
Nature, 526, 2015
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3F4I
 | | Crystal Structure of LeuT bound to L-selenomethionine and sodium | | 分子名称: | SELENOMETHIONINE, SODIUM ION, Transporter, ... | | 著者 | Singh, S.K, Piscitelli, C.L, Yamashita, A, Gouaux, E. | | 登録日 | 2008-10-31 | | 公開日 | 2008-12-23 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | A competitive inhibitor traps LeuT in an open-to-out conformation.
Science, 322, 2008
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3F4J
 | | Crystal structure of LeuT bound to glycine and sodium | | 分子名称: | GLYCINE, SODIUM ION, Transporter, ... | | 著者 | Singh, S.K, Piscitelli, C.L, Yamashita, A, Gouaux, E. | | 登録日 | 2008-10-31 | | 公開日 | 2008-12-23 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | A competitive inhibitor traps LeuT in an open-to-out conformation.
Science, 322, 2008
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