8CRY
 
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4XO0
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4XPC
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4XPE
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4XNO
 | | Crystal structure of 5'-CTTATPPPZZZATAAG | | 分子名称: | DNA (5'-D(*CP*TP*(BRU)P*AP*TP*(1WA)P*(1WA)P*(1WA)P*(1W5)P*(1W5)P*(1W5)P*AP*TP*AP*AP*G)-3') | | 著者 | Georgiadis, M.M, Singh, I. | | 登録日 | 2015-01-15 | | 公開日 | 2015-05-27 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.985 Å) | | 主引用文献 | Structural basis for a six nucleotide genetic alphabet.
J. Am. Chem. Soc., 137, 2015
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2O3C
 | | Crystal structure of zebrafish Ape | | 分子名称: | APEX nuclease 1, LEAD (II) ION | | 著者 | Georgiadis, M.M, Gaur, R.K, Delaplane, S, Svenson, J. | | 登録日 | 2006-12-01 | | 公開日 | 2007-12-11 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Evolution of the redox function in mammalian apurinic/apyrimidinic endonuclease
Mutat.Res., 643, 2008
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2O3H
 | | Crystal structure of the human C65A Ape | | 分子名称: | ACETATE ION, DNA-(apurinic or apyrimidinic site) lyase, SAMARIUM (III) ION | | 著者 | Georgiadis, M.M, Gaur, R.K, Delaplane, S, Svenson, J. | | 登録日 | 2006-12-01 | | 公開日 | 2007-12-11 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Evolution of the redox function in mammalian apurinic/apyrimidinic endonuclease
Mutat.Res., 643, 2008
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1MML
 | | MECHANISTIC IMPLICATIONS FROM THE STRUCTURE OF A CATALYTIC FRAGMENT OF MMLV REVERSE TRANSCRIPTASE | | 分子名称: | MMLV REVERSE TRANSCRIPTASE | | 著者 | Georgiadis, M.M, Jessen, S.M, Ogata, C.M, Telesnitsky, A, Goff, S.P, Hendrickson, W.A. | | 登録日 | 1995-07-18 | | 公開日 | 1995-10-15 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Mechanistic implications from the structure of a catalytic fragment of Moloney murine leukemia virus reverse transcriptase.
Structure, 3, 1995
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9BVD
 | | Crystal structure of SRY HMG box bound to DNA | | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(*CP*AP*CP*TP*AP*GP*CP*AP*TP*TP*GP*TP*TP*TP*GP*GP*G)-3'), DNA (5'-D(*GP*CP*CP*CP*AP*AP*AP*CP*AP*AP*TP*GP*CP*TP*AP*GP*TP*G)-3'), ... | | 著者 | Georgiadis, M.M. | | 登録日 | 2024-05-20 | | 公開日 | 2024-09-25 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | Role of nucleobase-specific interactions in the binding and bending of DNA by human male sex determination factor SRY.
J.Biol.Chem., 300, 2024
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8CRZ
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8CS0
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7UYO
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7UYN
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7UYP
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6MIH
 | | Crystal structure of host-guest complex with PC hachimoji DNA | | 分子名称: | DNA (5'-D(*CP*TP*TP*AP*(1WA)P*CP*(DB)P*T)-3'), DNA (5'-D(P*AP*(DS)P*GP*(1W5)P*TP*AP*AP*G)-3'), N-terminal fragment of MMLV reverse transcriptase | | 著者 | Georgiadis, M.M. | | 登録日 | 2018-09-19 | | 公開日 | 2019-02-27 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Hachimoji DNA and RNA: A genetic system with eight building blocks.
Science, 363, 2019
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6MIG
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6MIK
 | | Crystal structure of host-guest complex with PP hachimoji DNA | | 分子名称: | DNA (5'-D(*CP*TP*TP*AP*TP*(1WA)P*(1WA)P*(DS))-3'), DNA (5'-D(P*(DB)P*(1W5)P*(1W5)P*AP*TP*AP*AP*G)-3'), N-terminal fragment of MMLV reverse transcriptase | | 著者 | Georgiadis, M.M. | | 登録日 | 2018-09-19 | | 公開日 | 2019-02-27 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Hachimoji DNA and RNA: A genetic system with eight building blocks.
Science, 363, 2019
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6MKM
 | | Crystallographic solvent mapping analysis of DMSO/Tris bound to APE1 | | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DIMETHYL SULFOXIDE, ... | | 著者 | Georgiadis, M.M, He, H, Chen, Q. | | 登録日 | 2018-09-25 | | 公開日 | 2019-01-30 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.673 Å) | | 主引用文献 | Discovery of Macrocyclic Inhibitors of Apurinic/Apyrimidinic Endonuclease 1.
J. Med. Chem., 62, 2019
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6MK3
 | | Crystallographic solvent mapping analysis of DMSO bound to APE1 | | 分子名称: | 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, DNA-(apurinic or apyrimidinic site) lyase | | 著者 | Georgiadis, M.M, He, H, Chen, Q. | | 登録日 | 2018-09-24 | | 公開日 | 2019-01-30 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.478 Å) | | 主引用文献 | Discovery of Macrocyclic Inhibitors of Apurinic/Apyrimidinic Endonuclease 1.
J. Med. Chem., 62, 2019
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6MKO
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6MKK
 | | Crystallographic solvent mapping analysis of DMSO/Mg bound to APE1 | | 分子名称: | 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, DNA-(apurinic or apyrimidinic site) lyase, ... | | 著者 | Georgiadis, M.M, He, H, Chen, Q. | | 登録日 | 2018-09-25 | | 公開日 | 2019-01-30 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.442 Å) | | 主引用文献 | Discovery of Macrocyclic Inhibitors of Apurinic/Apyrimidinic Endonuclease 1.
J. Med. Chem., 62, 2019
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8DW1
 | | Crystal structure of a host-guest complex with 5'-CTTAGTTATAACTAAG-3' | | 分子名称: | DNA (5'-D(*CP*TP*TP*AP*GP*TP*TP*A)-3'), DNA (5'-D(P*TP*AP*AP*CP*TP*AP*AP*G)-3'), reverse transcriptase | | 著者 | Georgiadis, M.M. | | 登録日 | 2022-07-30 | | 公開日 | 2023-01-11 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.849 Å) | | 主引用文献 | Two distinct rotations of bithiazole DNA intercalation revealed by direct comparison of crystal structures of Co(III)•bleomycin A 2 and B 2 bound to duplex 5'-TAGTT sites.
Bioorg.Med.Chem., 77, 2023
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8DW8
 | | Host-guest structure of BLMA2 partially bound to 5'-ATTAGTTATAACTAAT-3' | | 分子名称: | BLEOMYCIN A2, DNA (5'-D(*AP*TP*TP*AP*GP*TP*TP*A)-3'), DNA (5'-D(P*TP*AP*AP*CP*TP*AP*AP*T)-3'), ... | | 著者 | Georgiadis, M.M. | | 登録日 | 2022-07-31 | | 公開日 | 2023-01-11 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | | 主引用文献 | Two distinct rotations of bithiazole DNA intercalation revealed by direct comparison of crystal structures of Co(III)•bleomycin A 2 and B 2 bound to duplex 5'-TAGTT sites.
Bioorg.Med.Chem., 77, 2023
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8DWM
 | | Host-guest complex of bleomycin A2 fully bound to CTTAGTTATAACTAAG | | 分子名称: | BLEOMYCIN A2, COBALT (III) ION, DNA (5'-D(*CP*TP*TP*AP*GP*TP*TP*A)-3'), ... | | 著者 | Georgiadis, M.M. | | 登録日 | 2022-08-01 | | 公開日 | 2023-01-11 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | | 主引用文献 | Two distinct rotations of bithiazole DNA intercalation revealed by direct comparison of crystal structures of Co(III)•bleomycin A 2 and B 2 bound to duplex 5'-TAGTT sites.
Bioorg.Med.Chem., 77, 2023
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1NIP
 | | CRYSTALLOGRAPHIC STRUCTURE OF THE NITROGENASE IRON PROTEIN FROM AZOTOBACTER VINELANDII | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, IRON/SULFUR CLUSTER, MAGNESIUM ION, ... | | 著者 | Komiya, H, Georgiadis, M.M, Chakrabarti, P, Woo, D, Kornuc, J.J, Rees, D.C. | | 登録日 | 1992-09-29 | | 公開日 | 1993-10-31 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystallographic structure of the nitrogenase iron protein from Azotobacter vinelandii.
Science, 257, 1992
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