4UX1
 
 | | Cryo-EM structure of antagonist-bound E2P gastric H,K-ATPase (SCH.E2. AlF) | | 分子名称: | POTASSIUM-TRANSPORTING ATPASE ALPHA CHAIN 1, POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA | | 著者 | Abe, K, Tani, K, Fujiyoshi, Y. | | 登録日 | 2014-08-18 | | 公開日 | 2014-09-17 | | 最終更新日 | 2014-11-12 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (8 Å) | | 主引用文献 | Systematic Comparison of Molecular Conformations of H+,K+-ATPase Reveals an Important Contribution of the A-M2 Linker for the Luminal Gating.
J.Biol.Chem., 289, 2014
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1OED
 | | STRUCTURE OF ACETYLCHOLINE RECEPTOR PORE FROM ELECTRON IMAGES | | 分子名称: | Acetylcholine receptor beta subunit, Acetylcholine receptor delta subunit, Acetylcholine receptor gamma subunit, ... | | 著者 | Miyazawa, A, Fujiyoshi, Y, Unwin, N. | | 登録日 | 2003-03-24 | | 公開日 | 2003-06-26 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Structure and Gating Mechanism of the Acetylcholine Receptor Pore.
Nature, 423, 2003
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8IF4
 | | Structure of human alpha-2/delta-1 without mirogabalin | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Voltage-dependent calcium channel subunit alpha-2/delta-1 | | 著者 | Kozai, D, Numoto, N, Fujiyoshi, Y. | | 登録日 | 2023-02-17 | | 公開日 | 2023-04-05 | | 最終更新日 | 2023-04-12 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Recognition Mechanism of a Novel Gabapentinoid Drug, Mirogabalin, for Recombinant Human alpha 2 delta 1, a Voltage-Gated Calcium Channel Subunit.
J.Mol.Biol., 435, 2023
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8IF3
 | | Structure of human alpha-2/delta-1 with mirogabalin | | 分子名称: | 2-[(1R,5S,6S)-6-(aminomethyl)-3-ethyl-6-bicyclo[3.2.0]hept-3-enyl]acetic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Kozai, D, Numoto, N, Fujiyoshi, Y. | | 登録日 | 2023-02-17 | | 公開日 | 2023-04-05 | | 最終更新日 | 2023-04-12 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Recognition Mechanism of a Novel Gabapentinoid Drug, Mirogabalin, for Recombinant Human alpha 2 delta 1, a Voltage-Gated Calcium Channel Subunit.
J.Mol.Biol., 435, 2023
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4UX2
 | | Cryo-EM structure of antagonist-bound E2P gastric H,K-ATPase (SCH.E2. MgF) | | 分子名称: | POTASSIUM-TRANSPORTING ATPASE ALPHA CHAIN 1, POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA | | 著者 | Abe, K, Tani, K, Fujiyoshi, Y. | | 登録日 | 2014-08-18 | | 公開日 | 2014-09-17 | | 最終更新日 | 2014-11-12 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (7 Å) | | 主引用文献 | Systematic Comparison of Molecular Conformations of H+,K+-ATPase Reveals an Important Contribution of the A-M2 Linker for the Luminal Gating.
J.Biol.Chem., 289, 2014
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4BGN
 | | cryo-EM structure of the NavCt voltage-gated sodium channel | | 分子名称: | VOLTAGE-GATED SODIUM CHANNEL | | 著者 | Tsai, C.J, Tani, K, Irie, K, Hiroaki, Y, Shimomura, T, Mcmillan, D.G, Cook, G.M, Schertler, G, Fujiyoshi, Y, Li, X.D. | | 登録日 | 2013-03-28 | | 公開日 | 2013-07-10 | | 最終更新日 | 2023-12-20 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (9 Å) | | 主引用文献 | Two Alternative Conformations of a Voltage-Gated Sodium Channel.
J.Mol.Biol., 425, 2013
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1AT9
 | | STRUCTURE OF BACTERIORHODOPSIN AT 3.0 ANGSTROM DETERMINED BY ELECTRON CRYSTALLOGRAPHY | | 分子名称: | BACTERIORHODOPSIN, RETINAL | | 著者 | Kimura, Y, Vassylyev, D.G, Miyazawa, A, Kidera, A, Matsushima, M, Mitsuoka, K, Murata, K, Hirai, T, Fujiyoshi, Y. | | 登録日 | 1997-08-20 | | 公開日 | 1998-09-16 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (2.8 Å) | | 主引用文献 | Surface of bacteriorhodopsin revealed by high-resolution electron crystallography.
Nature, 389, 1997
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5X93
 | | Human endothelin receptor type-B in complex with antagonist K-8794 | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3-[6-[(4-tert-butylphenyl)sulfonylamino]-5-(2-methoxyphenoxy)-2-pyrimidin-2-yl-pyrimidin-4-yl]oxy-N-(2,6-dimethylphenyl)propanamide, CHOLESTEROL, ... | | 著者 | Shihoya, W, Nishizawa, T, Yamashita, K, Hirata, K, Okuta, A, Tani, K, Fujiyoshi, Y, Doi, T, Nureki, O. | | 登録日 | 2017-03-05 | | 公開日 | 2017-08-16 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | X-ray structures of endothelin ETB receptor bound to clinical antagonist bosentan and its analog
Nat. Struct. Mol. Biol., 24, 2017
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5XPR
 | | Human endothelin receptor type-B in complex with antagonist bosentan | | 分子名称: | 4-tert-butyl-N-[6-(2-hydroxyethyloxy)-5-(2-methoxyphenoxy)-2-pyrimidin-2-yl-pyrimidin-4-yl]benzenesulfonamide, Endothelin B receptor,Endolysin,Endothelin B receptor, SULFATE ION | | 著者 | Shihoya, W, Nishizawa, T, Yamashita, K, Hirata, K, Okuta, A, Tani, K, Fujiyoshi, Y, Doi, T, Nureki, O. | | 登録日 | 2017-06-04 | | 公開日 | 2017-08-16 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | X-ray structures of endothelin ETB receptor bound to clinical antagonist bosentan and its analog
Nat. Struct. Mol. Biol., 24, 2017
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4P79
 | | Crystal structure of mouse claudin-15 | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Claudin-15 | | 著者 | Suzuki, H, Nishizawa, T, Tani, K, Yamazaki, Y, Tamura, A, Ishitani, R, Dohmae, N, Tsukita, S, Nureki, O, Fujiyoshi, Y. | | 登録日 | 2014-03-26 | | 公開日 | 2014-04-30 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structure of a claudin provides insight into the architecture of tight junctions.
Science, 344, 2014
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1FQY
 | | STRUCTURE OF AQUAPORIN-1 AT 3.8 A RESOLUTION BY ELECTRON CRYSTALLOGRAPHY | | 分子名称: | AQUAPORIN-1 | | 著者 | Murata, K, Mitsuoka, K, Hirai, T, Walz, T, Agre, P, Heymann, J.B, Engel, A, Fujiyoshi, Y. | | 登録日 | 2000-09-07 | | 公開日 | 2000-10-18 | | 最終更新日 | 2024-04-17 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (3.8 Å) | | 主引用文献 | Structural determinants of water permeation through aquaporin-1.
Nature, 407, 2000
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1L9H
 | | Crystal structure of bovine rhodopsin at 2.6 angstroms RESOLUTION | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HEPTANE-1,2,3-TRIOL, MERCURY (II) ION, ... | | 著者 | Okada, T, Fujiyoshi, Y, Silow, M, Navarro, J, Landau, E.M, Shichida, Y. | | 登録日 | 2002-03-23 | | 公開日 | 2002-05-15 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Functional role of internal water molecules in rhodopsin revealed by X-ray crystallography.
Proc.Natl.Acad.Sci.USA, 99, 2002
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1I2H
 | | CRYSTAL STRUCTURE ANALYSIS OF PSD-ZIP45(HOMER1C/VESL-1L)CONSERVED HOMER 1 DOMAIN | | 分子名称: | PSD-ZIP45(HOMER-1C/VESL-1L) | | 著者 | Irie, K, Nakatsu, T, Mitsuoka, K, Fujiyoshi, Y, Kato, H. | | 登録日 | 2001-02-09 | | 公開日 | 2002-05-29 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal Structure of the Homer 1 Family Conserved Region Reveals the Interaction Between the EVH1 Domain and
Own Proline-rich Motif
J.Mol.Biol., 318, 2002
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3IYZ
 | | Structure of Aquaporin-4 S180D mutant at 10.0 A resolution from electron micrograph | | 分子名称: | Aquaporin-4 | | 著者 | Mitsuma, T, Tani, K, Hiroaki, Y, Kamegawa, A, Suzuki, H, Hibino, H, Kurachi, Y, Fujiyoshi, Y. | | 登録日 | 2010-07-24 | | 公開日 | 2010-08-25 | | 最終更新日 | 2023-09-06 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (10 Å) | | 主引用文献 | Influence of the cytoplasmic domains of aquaporin-4 on water conduction and array formation.
J.Mol.Biol., 402, 2010
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6AKG
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6AKE
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3IZ1
 | | C-alpha model fitted into the EM structure of Cx26M34A | | 分子名称: | Gap junction beta-2 protein | | 著者 | Oshima, A, Tani, K, Toloue, M.M, Hiroaki, Y, Smock, A, Inukai, S, Cone, A, Nicholson, B.J, Sosinsky, G.E, Fujiyoshi, Y. | | 登録日 | 2010-08-19 | | 公開日 | 2010-11-03 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (6 Å) | | 主引用文献 | Asymmetric configurations and N-terminal rearrangements in connexin26 gap junction channels.
J.Mol.Biol., 405, 2011
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3IZ2
 | | C-alpha model fitted into the EM structure of Cx26M34Adel2-7 | | 分子名称: | Gap junction beta-2 protein | | 著者 | Oshima, A, Tani, K, Toloue, M.M, Hiroaki, Y, Smock, A, Inukai, S, Cone, A, Nicholson, B.J, Sosinsky, G.E, Fujiyoshi, Y. | | 登録日 | 2010-08-19 | | 公開日 | 2010-11-03 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (10 Å) | | 主引用文献 | Asymmetric configurations and N-terminal rearrangements in connexin26 gap junction channels.
J.Mol.Biol., 405, 2011
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2AT9
 | | STRUCTURE OF BACTERIORHODOPSIN AT 3.0 ANGSTROM BY ELECTRON CRYSTALLOGRAPHY | | 分子名称: | 3-[[3-METHYLPHOSPHONO-GLYCEROLYL]PHOSPHONYL]-[1,2-DI[2,6,10,14-TETRAMETHYL-HEXADECAN-16-YL]GLYCEROL, BACTERIORHODOPSIN, RETINAL | | 著者 | Mitsuoka, K, Hirai, T, Murata, K, Miyazawa, A, Kidera, A, Kimura, Y, Fujiyoshi, Y. | | 登録日 | 1998-12-17 | | 公開日 | 1999-04-27 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (3 Å) | | 主引用文献 | The structure of bacteriorhodopsin at 3.0 A resolution based on electron crystallography: implication of the charge distribution.
J.Mol.Biol., 286, 1999
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3X29
 | | CRYSTAL STRUCTURE of MOUSE CLAUDIN-19 IN COMPLEX with C-TERMINAL FRAGMENT OF CLOSTRIDIUM PERFRINGENS ENTEROTOXIN | | 分子名称: | Claudin-19, Heat-labile enterotoxin B chain | | 著者 | Saitoh, Y, Suzuki, H, Tani, K, Nishikawa, K, Irie, K, Ogura, Y, Tamura, A, Tsukita, S, Fujiyoshi, Y. | | 登録日 | 2014-12-13 | | 公開日 | 2015-01-21 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | | 主引用文献 | Structural insight into tight junction disassembly by Clostridium perfringens enterotoxin
Science, 347, 2015
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6ACH
 | | Structure of NAD+-bound leucine dehydrogenase from Geobacillus stearothermophilus by cryo-EM | | 分子名称: | Leucine dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | 著者 | Yamaguchi, H, Kamegawa, A, Nakata, K, Kashiwagi, T, Mizukoshi, T, Fujiyoshi, Y, Tani, K. | | 登録日 | 2018-07-26 | | 公開日 | 2018-12-26 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural insights into thermostabilization of leucine dehydrogenase from its atomic structure by cryo-electron microscopy
J. Struct. Biol., 205, 2019
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7WSV
 | | Cryo-EM structure of the N-terminal deletion mutant of human pannexin-1 in a nanodisc | | 分子名称: | Pannexin-1 | | 著者 | Kuzuya, M, Hirano, H, Hayashida, K, Watanabe, M, Kobayashi, K, Tani, K, Fujiyoshi, Y, Oshima, A. | | 登録日 | 2022-02-01 | | 公開日 | 2022-02-16 | | 最終更新日 | 2022-02-23 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Structures of human pannexin-1 in nanodiscs reveal gating mediated by dynamic movement of the N terminus and phospholipids.
Sci.Signal., 15, 2022
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2ZZ9
 | | Structure of aquaporin-4 S180D mutant at 2.8 A resolution by electron crystallography | | 分子名称: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, Aquaporin-4 | | 著者 | Tani, K, Mitsuma, T, Hiroaki, Y, Kamegawa, A, Nishikawa, K, Tanimura, Y, Fujiyoshi, Y. | | 登録日 | 2009-02-06 | | 公開日 | 2009-06-09 | | 最終更新日 | 2023-11-08 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (2.8 Å) | | 主引用文献 | Mechanism of Aquaporin-4's Fast and Highly Selective Water Conduction and Proton Exclusion.
J.Mol.Biol., 389, 2009
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3IXZ
 | | Pig gastric H+/K+-ATPase complexed with aluminium fluoride | | 分子名称: | Potassium-transporting ATPase alpha, Potassium-transporting ATPase subunit beta | | 著者 | Abe, K, Tani, K, Nishizawa, T, Fujiyoshi, Y. | | 登録日 | 2009-03-09 | | 公開日 | 2009-06-23 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (6.5 Å) | | 主引用文献 | Inter-subunit interaction of gastric H+,K+-ATPase prevents reverse reaction of the transport cycle
Embo J., 28, 2009
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2B6P
 | | X-ray structure of lens Aquaporin-0 (AQP0) (lens MIP) in an open pore state | | 分子名称: | Lens fiber major intrinsic protein | | 著者 | Gonen, T, Cheng, Y, Sliz, P, Hiroaki, Y, Fujiyoshi, Y, Harrison, S.C, Walz, T. | | 登録日 | 2005-10-03 | | 公開日 | 2005-12-06 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Lipid-protein interactions in double-layered two-dimensional AQP0 crystals.
Nature, 438, 2005
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