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3F5C
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Structure of Dax-1:LRH-1 complex
分子名称: Nuclear receptor subfamily 0 group B member 1, Nuclear receptor subfamily 5 group A member 2
著者Fletterick, R.J, Sablin, E.P.
登録日2008-11-03
公開日2008-12-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The structure of corepressor Dax-1 bound to its target nuclear receptor LRH-1.
Proc.Natl.Acad.Sci.USA, 105, 2008
1ANB
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BU of 1anb by Molmil
ANIONIC TRYPSIN MUTANT WITH SER 214 REPLACED BY GLU
分子名称: ANIONIC TRYPSIN, BENZAMIDINE, CALCIUM ION
著者Fletterick, R.J, Mcgrath, M.E.
登録日1994-12-21
公開日1997-04-01
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Perturbing the polar environment of Asp102 in trypsin: consequences of replacing conserved Ser214.
Biochemistry, 31, 1992
1AND
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BU of 1and by Molmil
ANIONIC TRYPSIN MUTANT WITH ARG 96 REPLACED BY HIS
分子名称: ANIONIC TRYPSIN, BENZAMIDINE, COPPER (II) ION
著者Fletterick, R.J, Mcgrath, M.E.
登録日1994-12-21
公開日1997-04-01
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of an engineered, metal-actuated switch in trypsin.
Biochemistry, 32, 1993
1ANC
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BU of 1anc by Molmil
ANIONIC TRYPSIN MUTANT WITH SER 214 REPLACED BY LYS
分子名称: ANIONIC TRYPSIN, BENZAMIDINE, CALCIUM ION
著者Fletterick, R.J, Mcgrath, M.E.
登録日1994-12-21
公開日1997-04-01
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Perturbing the polar environment of Asp102 in trypsin: consequences of replacing conserved Ser214.
Biochemistry, 31, 1992
1ANE
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BU of 1ane by Molmil
ANIONIC TRYPSIN WILD TYPE
分子名称: ANIONIC TRYPSIN, BENZAMIDINE
著者Fletterick, R.J, Mcgrath, M.E.
登録日1994-12-21
公開日1997-04-01
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of an engineered, metal-actuated switch in trypsin.
Biochemistry, 32, 1993
1F29
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BU of 1f29 by Molmil
CRYSTAL STRUCTURE ANALYSIS OF CRUZAIN BOUND TO A VINYL SULFONE DERIVED INHIBITOR (I)
分子名称: 3-[[N-[MORPHOLIN-N-YL]-CARBONYL]-PHENYLALANINYL-AMINO]-5- PHENYL-PENTANE-1-SULFONYLBENZENE, CRUZAIN
著者Brinen, L.S, Hansell, E, Roush, W.R, McKerrow, J.H, Fletterick, R.J.
登録日2000-05-23
公開日2000-07-26
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献A target within the target: probing cruzain's P1' site to define structural determinants for the Chagas' disease protease.
Structure Fold.Des., 8, 2000
1MDU
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BU of 1mdu by Molmil
Crystal structure of the chicken actin trimer complexed with human gelsolin segment 1 (GS-1)
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, ...
著者Dawson, J.F, Sablin, E.P, Spudich, J.A, Fletterick, R.J.
登録日2002-08-07
公開日2003-01-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of an F-actin trimer disrupted by gelsolin and implications for the mechanism of severing
J.Biol.Chem., 278, 2003
2AIM
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BU of 2aim by Molmil
CRUZAIN INHIBITED WITH BENZOYL-ARGININE-ALANINE-FLUOROMETHYLKETONE
分子名称: BENZOYL-ARGININE-ALANINE-FLUORO-METHYL KETONE, CRUZAIN
著者Gillmor, S.A, Fletterick, R.J.
登録日1997-04-21
公開日1997-10-22
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural determinants of specificity in the cysteine protease cruzain.
Protein Sci., 6, 1997
6DDA
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BU of 6dda by Molmil
Nurr1 Covalently Modified by a Dopamine Metabolite
分子名称: 5-hydroxy-1,2-dihydro-6H-indol-6-one, BROMIDE ION, Nuclear receptor subfamily 4 group A member 2, ...
著者Bruning, J.M, Wang, Y, Otrabella, F, Boxue, T, Liu, H, Bhattacharya, P, Guo, S, Holton, J.M, Fletterick, R.J, Jacobson, M.P, England, P.M.
登録日2018-05-09
公開日2019-03-20
最終更新日2019-11-06
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Covalent Modification and Regulation of the Nuclear Receptor Nurr1 by a Dopamine Metabolite.
Cell Chem Biol, 26, 2019
2Z4J
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BU of 2z4j by Molmil
Crystal structure of AR LBD with SHP peptide NR Box 2
分子名称: 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, Nuclear receptor 0B2
著者Jouravel, N, Fletterick, R.J.
登録日2007-06-19
公開日2007-12-04
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Interaction between the androgen receptor and a segment of its corepressor SHP
Acta Crystallogr.,Sect.D, 63, 2007
1YGP
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BU of 1ygp by Molmil
PHOSPHORYLATED FORM OF YEAST GLYCOGEN PHOSPHORYLASE WITH PHOSPHATE BOUND IN THE ACTIVE SITE.
分子名称: PHOSPHATE ION, PYRIDOXAL-5'-PHOSPHATE, YEAST GLYCOGEN PHOSPHORYLASE
著者Lin, K, Rath, V.L, Dai, S.C, Fletterick, R.J, Hwang, P.K.
登録日1996-05-30
公開日1996-12-23
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A protein phosphorylation switch at the conserved allosteric site in GP.
Science, 273, 1996
3I00
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BU of 3i00 by Molmil
Crystal Structure of the huntingtin interacting protein 1 coiled coil domain
分子名称: Huntingtin-interacting protein 1
著者Wilbur, J.D, Hwang, P.K, Brodsky, F.M, Fletterick, R.J.
登録日2009-06-24
公開日2010-02-23
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Accommodation of structural rearrangements in the huntingtin-interacting protein 1 coiled-coil domain.
Acta Crystallogr.,Sect.D, 66, 2010
3LVG
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BU of 3lvg by Molmil
Crystal structure of a clathrin heavy chain and clathrin light chain complex
分子名称: Clathrin heavy chain 1, Clathrin light chain B
著者Wilbur, J.D, Hwang, P.K, Ybe, J.A, Lane, M, Sellers, B.D, Jacobson, M.P, Fletterick, R.J, Brodsky, F.M.
登録日2010-02-20
公開日2010-06-09
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (7.94 Å)
主引用文献Conformation switching of clathrin light chain regulates clathrin lattice assembly.
Dev.Cell, 18, 2010
3LVH
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Crystal structure of a clathrin heavy chain and clathrin light chain complex
分子名称: Clathrin heavy chain 1, Clathrin light chain B
著者Wilbur, J.D, Hwang, P.K, Ybe, J.A, Lane, M, Sellers, B.D, Jacobson, M.P, Fletterick, R.J, Brodsky, F.M.
登録日2010-02-20
公開日2010-06-09
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (9 Å)
主引用文献Conformation switching of clathrin light chain regulates clathrin lattice assembly.
Dev.Cell, 18, 2010
1HGX
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BU of 1hgx by Molmil
HYPOXANTHINE-GUANINE-XANTHINE PHOSPHORIBOSYLTRANSFERASE (HGXPRTASE)
分子名称: GUANOSINE-5'-MONOPHOSPHATE, HYPOXANTHINE-GUANINE-XANTHINE PHOSPHORIBOSYLTRANSFERASE, SULFATE ION
著者Somoza, J.R, Wang, C.C, Fletterick, R.J.
登録日1996-03-12
公開日1996-08-17
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the hypoxanthine-guanine-xanthine phosphoribosyltransferase from the protozoan parasite Tritrichomonas foetus.
Biochemistry, 35, 1996
3F7D
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BU of 3f7d by Molmil
SF-1 LBD bound by phosphatidylcholine
分子名称: (2S)-2-{[(1R)-1-hydroxyhexadecyl]oxy}-3-{[(1R)-1-hydroxyoctadecyl]oxy}propyl 2-(trimethylammonio)ethyl phosphate, Peroxisome proliferator-activated receptor gamma coactivator 1-alpha, nuclear receptor SF-1
著者Sablin, E.P, Fletterick, R.J.
登録日2008-11-07
公開日2008-12-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of SF-1 bound by different phospholipids: evidence for regulatory ligands.
Mol.Endocrinol., 23, 2009
3COB
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BU of 3cob by Molmil
Structural Dynamics of the Microtubule binding and regulatory elements in the Kinesin-like Calmodulin binding protein
分子名称: ADENOSINE-5'-DIPHOSPHATE, Kinesin heavy chain-like protein, MAGNESIUM ION
著者Vinogradova, M.V, Malanina, G.G, Reddy, V, Reddy, A.S.N, Fletterick, R.J.
登録日2008-03-27
公開日2008-06-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural dynamics of the microtubule binding and regulatory elements in the kinesin-like calmodulin binding protein.
J.Struct.Biol., 163, 2008
3CNZ
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Structural dynamics of the microtubule binding and regulatory elements in the kinesin-like calmodulin binding protein
分子名称: ADENOSINE-5'-DIPHOSPHATE, Kinesin heavy chain-like protein, MAGNESIUM ION
著者Vinogradova, M.V, Malanina, G.G, Reddy, V, Reddy, A.S.N, Fletterick, R.J.
登録日2008-03-26
公開日2008-06-17
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural dynamics of the microtubule binding and regulatory elements in the kinesin-like calmodulin binding protein.
J.Struct.Biol., 163, 2008
1XZX
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BU of 1xzx by Molmil
Thyroxine-Thyroid Hormone Receptor Interactions
分子名称: 3,5,3'TRIIODOTHYRONINE, CACODYLATE ION, Thyroid hormone receptor beta-1
著者Sandler, B, Webb, P, Apriletti, J.W, Huber, B.R, Togashi, M, Cunha Lima, S.T, Juric, S, Nilsson, S, Wagner, R, Fletterick, R.J, Baxter, J.D.
登録日2004-11-12
公開日2004-12-07
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Thyroxine-thyroid hormone receptor interactions.
J.Biol.Chem., 279, 2004
1YMT
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BU of 1ymt by Molmil
Mouse SF-1 LBD
分子名称: 1-CIS-9-OCTADECANOYL-2-CIS-9-HEXADECANOYL PHOSPHATIDYL GLYCEROL, Nuclear receptor 0B2, Steroidogenic factor 1
著者Krylova, I.N, Sablin, E.P, Moore, J, Xu, R.X, Waitt, G.M, Juzumiene, D, Bynum, J.M, Fletterick, R.J, Willson, T.M, Ingraham, H.A.
登録日2005-01-21
公開日2005-03-15
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF-1 and LRH-1
Cell(Cambridge,Mass.), 120, 2005
1YV0
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BU of 1yv0 by Molmil
Crystal structure of skeletal muscle troponin in the Ca2+-free state
分子名称: MAGNESIUM ION, Troponin C, skeletal muscle, ...
著者Vinogradova, M.V, Stone, D.B, Malanina, G.G, Karatzaferi, C, Cooke, R, Mendelson, R.A, Fletterick, R.J.
登録日2005-02-14
公開日2005-04-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (7 Å)
主引用文献Ca2+-regulated structural changes in troponin
Proc.Natl.Acad.Sci.USA, 102, 2005
1YOK
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crystal structure of human LRH-1 bound with TIF-2 peptide and phosphatidylglycerol
分子名称: (2S)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(6E)-HEXADEC-6-ENOYLOXY]PROPYL (8E)-OCTADEC-8-ENOATE, Nuclear receptor coactivator 2, Orphan nuclear receptor NR5A2
著者Krylova, I.N, Sablin, E.P, Moore, J, Xu, R.X, Waitt, G.M, MacKay, J.A, Juzumiene, D, Bynum, J.M, Madauss, K, Montana, V, Lebedeva, L, Suzawa, M, Williams, J.D, Williams, S.P, Guy, R.K, Thornton, J.W, Fletterick, R.J, Willson, T.M, Ingraham, H.A.
登録日2005-01-27
公開日2005-07-19
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF-1 and LRH-1.
Cell(Cambridge,Mass.), 120, 2005
1YTZ
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Crystal structure of skeletal muscle troponin in the Ca2+-activated state
分子名称: ALPHA-[4-(1,1,3,3 - TETRAMETHYLBUTYL)PHENYL]-OMEGA-HYDROXY-POLY(OXY-1,2-ETHANEDIYL), CALCIUM ION, Troponin C, ...
著者Vinogradova, M.V, Stone, D.B, Malanina, G.G, Karatzaferi, C, Cooke, R, Mendelson, R.A, Fletterick, R.J.
登録日2005-02-11
公開日2005-04-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Ca2+-regulated structural changes in troponin
Proc.Natl.Acad.Sci.Usa, 102, 2005
1XJ7
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Complex Androgen Receptor LBD and RAC3 peptide
分子名称: 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, RAC3 derived peptide
著者Estebanez-Perpina, E, Moore, J.M.R, Mar, E, Nguyen, P, Delgado-Rodrigues, E, Baxter, J.D, Buehrer, B.M, Webb, P, Fletterick, R.J, Guy, R.K.
登録日2004-09-22
公開日2005-01-25
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The Molecular Mechanisms of Coactivator Utilization in Ligand-dependent Transactivation by the Androgen Receptor
J.Biol.Chem., 280, 2005
1Y0X
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Thyroxine-Thyroid Hormone Receptor Interactions
分子名称: 3,5,3',5'-TETRAIODO-L-THYRONINE, CACODYLATE ION, Thyroid hormone receptor beta-1
著者Sandler, B, Webb, P, Apriletti, J.W, Huber, B.R, Togashi, M, Cunha Lima, S.T, Juric, S, Nilsson, S, Wagner, R, Fletterick, R.J, Baxter, J.D.
登録日2004-11-16
公開日2004-12-07
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Thyroxine-thyroid hormone receptor interactions.
J.Biol.Chem., 279, 2004

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