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1EXK
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BU of 1exk by Molmil
SOLUTION STRUCTURE OF THE CYSTEINE-RICH DOMAIN OF THE ESCHERICHIA COLI CHAPERONE PROTEIN DNAJ.
分子名称: DNAJ PROTEIN, ZINC ION
著者Martinez-Yamout, M, Legge, G.B, Zhang, O, Wright, P.E, Dyson, H.J.
登録日2000-05-03
公開日2000-07-26
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of the cysteine-rich domain of the Escherichia coli chaperone protein DnaJ.
J.Mol.Biol., 300, 2000
5HPD
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BU of 5hpd by Molmil
Solution Structure of TAZ2-p53TAD
分子名称: CREB-binding protein,Cellular tumor antigen p53 fusion protein, ZINC ION
著者Krois, A.S, Ferreon, J.C, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E.
登録日2016-01-20
公開日2016-03-16
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Recognition of the disordered p53 transactivation domain by the transcriptional adapter zinc finger domains of CREB-binding protein.
Proc.Natl.Acad.Sci.USA, 113, 2016
5HOU
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BU of 5hou by Molmil
Solution Structure of p53TAD-TAZ1
分子名称: Cellular tumor antigen p53,CREB-binding protein fusion protein, ZINC ION
著者Krois, A.S, Ferreon, J.C, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E.
登録日2016-01-19
公開日2016-03-16
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Recognition of the disordered p53 transactivation domain by the transcriptional adapter zinc finger domains of CREB-binding protein.
Proc.Natl.Acad.Sci.USA, 113, 2016
6WLH
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BU of 6wlh by Molmil
RNA complex of WT1 zinc finger transcription factor
分子名称: RNA (29-MER), Wilms tumor protein, ZINC ION
著者Wright, P.E, Dyson, H.J.
登録日2020-04-20
公開日2021-03-03
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献RNA Binding by the KTS Splice Variants of Wilms' Tumor Suppressor Protein WT1.
Biochemistry, 59, 2020
7LVS
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BU of 7lvs by Molmil
The CBP TAZ1 Domain in Complex with a CITED2-HIF-1-Alpha Fusion Peptide
分子名称: Cbp/p300-interacting transactivator 2,Hypoxia-inducible factor 1-alpha, Histone lysine acetyltransferase CREBBP, ZINC ION
著者Appling, F.D, Berlow, R.B, Stanfield, R.L, Dyson, H.J, Wright, P.E.
登録日2021-02-26
公開日2021-07-28
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献The molecular basis of allostery in a facilitated dissociation process.
Structure, 29, 2021
2HDP
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BU of 2hdp by Molmil
Solution Structure of Hdm2 RING Finger Domain
分子名称: Ubiquitin-protein ligase E3 Mdm2, ZINC ION
著者Kostic, M, Matt, T, Yamout-Martinez, M, Dyson, H.J, Wright, P.E.
登録日2006-06-20
公開日2006-11-21
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the Hdm2 C2H2C4 RING, a domain critical for ubiquitination of p53.
J.Mol.Biol., 363, 2006
5HP0
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BU of 5hp0 by Molmil
Solution Structure of TAZ2-p53AD2
分子名称: CREB-binding protein,Cellular tumor antigen p53 fusion protein, ZINC ION
著者Krois, A.S, Ferreon, J.C, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E.
登録日2016-01-19
公開日2016-03-16
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Recognition of the disordered p53 transactivation domain by the transcriptional adapter zinc finger domains of CREB-binding protein.
Proc.Natl.Acad.Sci.USA, 113, 2016
6UNA
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BU of 6una by Molmil
Crystal structure of inactive p38gamma
分子名称: GLYCEROL, Mitogen-activated protein kinase 12, SULFATE ION
著者Aoto, P.C, Stanfield, R.L, Wilson, I.A, Dyson, H.J, Wright, P.E.
登録日2019-10-11
公開日2019-12-18
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.554 Å)
主引用文献A Dynamic Switch in Inactive p38 gamma Leads to an Excited State on the Pathway to an Active Kinase.
Biochemistry, 58, 2019
6V8U
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BU of 6v8u by Molmil
Kaiso (ZBTB33) zinc finger DNA binding domain in complex with a modified Kaiso binding sequence (KBS)
分子名称: CHLORIDE ION, DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*GP*GP*CP*AP*CP*GP*AP*AP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*CP*GP*TP*GP*CP*CP*AP*AP*TP*AP*AP*CP*G)-3'), ...
著者Nikolova, E.N, Stanfield, R.L, Dyson, H.J, Wright, P.E.
登録日2019-12-12
公開日2020-04-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.103 Å)
主引用文献A Conformational Switch in the Zinc Finger Protein Kaiso Mediates Differential Readout of Specific and Methylated DNA Sequences.
Biochemistry, 59, 2020
8T5X
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BU of 8t5x by Molmil
Probing the dissociation pathway of a kinetically labile transthyretin mutant (A25T)
分子名称: Transthyretin
著者Ferguson, J.A, Sun, X, Leach, B.I, Stanfield, R.L, Dyson, H.J, Wright, P.E.
登録日2023-06-14
公開日2023-08-02
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Probing the Dissociation Pathway of a Kinetically Labile Transthyretin Mutant.
J.Am.Chem.Soc., 146, 2024
6DFA
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BU of 6dfa by Molmil
Kaiso (ZBTB33) E535A zinc finger DNA binding domain in complex with the specific Kaiso binding sequence (KBS)
分子名称: CHLORIDE ION, DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*GP*GP*CP*AP*GP*GP*AP*AP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*CP*CP*TP*GP*CP*CP*AP*AP*TP*AP*AP*CP*G)-3'), ...
著者Nikolova, E.N, Stanfield, R.L, Dyson, H.J, Wright, P.E.
登録日2018-05-14
公開日2019-05-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.908 Å)
主引用文献A conformational switch in the zinc finger protein Kaiso mediates differential readout of specific and methylated DNA sequences.
Biochemistry, 2020
6DF9
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BU of 6df9 by Molmil
Kaiso (ZBTB33) E535Q zinc finger DNA binding domain in complex with the specific Kaiso binding sequence (KBS)
分子名称: CHLORIDE ION, DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*GP*GP*CP*AP*GP*GP*AP*AP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*CP*CP*TP*GP*CP*CP*AP*AP*TP*AP*AP*CP*G)-3'), ...
著者Nikolova, E.N, Stanfield, R.L, Dyson, H.J, Wright, P.E.
登録日2018-05-14
公開日2019-05-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.319 Å)
主引用文献A conformational switch in the zinc finger protein Kaiso mediates differential readout of specific and methylated DNA sequences.
Biochemistry, 2020
6DF8
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BU of 6df8 by Molmil
Kaiso (ZBTB33) zinc finger DNA binding domain in complex with the specific Kaiso binding sequence (KBS), pH 6.5
分子名称: CHLORIDE ION, DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*GP*GP*CP*AP*GP*GP*AP*AP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*CP*CP*TP*GP*CP*CP*AP*AP*TP*AP*AP*CP*G)-3'), ...
著者Nikolova, E.N, Stanfield, R.L, Dyson, H.J, Wright, P.E.
登録日2018-05-14
公開日2019-05-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.536 Å)
主引用文献A conformational switch in the zinc finger protein Kaiso mediates differential readout of specific and methylated DNA sequences.
Biochemistry, 2020
1XOB
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BU of 1xob by Molmil
THIOREDOXIN (REDUCED DITHIO FORM), NMR, 20 STRUCTURES
分子名称: THIOREDOXIN
著者Jeng, M.-F, Campbell, A.P, Begley, T, Holmgren, A, Case, D.A, Wright, P.E, Dyson, H.J.
登録日1995-11-28
公開日1996-06-10
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献High-resolution solution structures of oxidized and reduced Escherichia coli thioredoxin.
Structure, 2, 1994
1XOA
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BU of 1xoa by Molmil
THIOREDOXIN (OXIDIZED DISULFIDE FORM), NMR, 20 STRUCTURES
分子名称: THIOREDOXIN
著者Jeng, M.-F, Campbell, A.P, Begley, T, Holmgren, A, Case, D.A, Wright, P.E, Dyson, H.J.
登録日1995-11-28
公開日1996-06-10
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献High-resolution solution structures of oxidized and reduced Escherichia coli thioredoxin.
Structure, 2, 1994
6DF5
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BU of 6df5 by Molmil
Kaiso (ZBTB33) zinc finger DNA binding domain in complex with the specific Kaiso binding sequence (KBS)
分子名称: CHLORIDE ION, DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*GP*GP*CP*AP*GP*GP*AP*AP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*CP*CP*TP*GP*CP*CP*AP*AP*TP*AP*AP*CP*G)-3'), ...
著者Nikolova, E.N, Stanfield, R.L, Dyson, H.J, Wright, P.E.
登録日2018-05-14
公開日2019-05-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.819 Å)
主引用文献A conformational switch in the zinc finger protein Kaiso mediates differential readout of specific and methylated DNA sequences.
Biochemistry, 2020
6DFB
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BU of 6dfb by Molmil
Kaiso (ZBTB33) K539A zinc finger DNA binding domain in complex with the specific Kaiso binding sequence (KBS)
分子名称: CHLORIDE ION, DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*GP*GP*CP*AP*GP*GP*AP*AP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*CP*CP*TP*GP*CP*CP*AP*AP*TP*AP*AP*CP*G)-3'), ...
著者Nikolova, E.N, Stanfield, R.L, Dyson, H.J, Wright, P.E.
登録日2018-05-14
公開日2019-05-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献A conformational switch in the zinc finger protein Kaiso mediates differential readout of specific and methylated DNA sequences.
Biochemistry, 2020
6DFC
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BU of 6dfc by Molmil
Kaiso (ZBTB33) zinc finger DNA binding domain in complex with the specific Kaiso binding sequence (KBS) with a T-to-U substitution
分子名称: CHLORIDE ION, DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*GP*GP*CP*AP*AP*GP*AP*AP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*CP*UP*TP*GP*CP*CP*AP*AP*TP*AP*AP*CP*G)-3'), ...
著者Nikolova, E.N, Stanfield, R.L, Dyson, H.J, Wright, P.E.
登録日2018-05-14
公開日2019-05-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献A conformational switch in the zinc finger protein Kaiso mediates differential readout of specific and methylated DNA sequences.
Biochemistry, 2020
5U6H
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BU of 5u6h by Molmil
Solution structure of the zinc fingers 1 and 2 of MBNL1
分子名称: Muscleblind-like protein 1, ZINC ION
著者Phukan, P.D, Park, S, Martinez-Yamout, M.M, Zeeb, M, Dyson, H.J, Wright, P.E.
登録日2016-12-08
公開日2017-08-02
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural Basis for Interaction of the Tandem Zinc Finger Domains of Human Muscleblind with Cognate RNA from Human Cardiac Troponin T.
Biochemistry, 56, 2017
5U6L
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BU of 5u6l by Molmil
Solution structure of the zinc fingers 3 and 4 of MBNL1
分子名称: Muscleblind-like protein 1, ZINC ION
著者Phukan, P.D, Park, S, Martinez-Yamout, M.M, Zeeb, M, Dyson, H.J, Wright, P.E.
登録日2016-12-08
公開日2017-08-02
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural Basis for Interaction of the Tandem Zinc Finger Domains of Human Muscleblind with Cognate RNA from Human Cardiac Troponin T.
Biochemistry, 56, 2017
5U9B
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BU of 5u9b by Molmil
Solution structure of the zinc fingers 1 and 2 of MBNL1 in complex with human cardiac troponin T pre-mRNA
分子名称: Muscleblind-like protein 1, RNA (5'-R(P*GP*UP*CP*UP*CP*GP*CP*UP*UP*UP*UP*CP*CP*CP*C)-3'), ZINC ION
著者Phukan, P.D, Park, S, Martinez-Yamout, M.M, Zeeb, M, Dyson, H.J, Wright, P.E.
登録日2016-12-15
公開日2017-08-02
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural Basis for Interaction of the Tandem Zinc Finger Domains of Human Muscleblind with Cognate RNA from Human Cardiac Troponin T.
Biochemistry, 56, 2017
5VMV
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BU of 5vmv by Molmil
Kaiso (ZBTB33) zinc finger DNA binding domain in complex with its double CpG-methylated DNA consensus binding site
分子名称: CHLORIDE ION, DNA (5'-D(*TP*GP*CP*TP*TP*CP*TP*(5CM)P*GP*(5CM)P*GP*AP*GP*AP*AP*GP*CP*A)-3'), Transcriptional regulator Kaiso, ...
著者Nikolova, E.N, Stanfield, R.L, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E.
登録日2017-04-28
公開日2018-04-04
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.313 Å)
主引用文献CH···O Hydrogen Bonds Mediate Highly Specific Recognition of Methylated CpG Sites by the Zinc Finger Protein Kaiso.
Biochemistry, 57, 2018
5VMX
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BU of 5vmx by Molmil
Kaiso (ZBTB33) zinc finger DNA binding domain in complex with a hemi CpG-methylated DNA resembling the specific Kaiso binding sequence (KBS)
分子名称: CHLORIDE ION, DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*CP*GP*CP*GP*GP*GP*AP*AP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*CP*CP*(5CM)P*GP*(5CM)P*GP*AP*AP*TP*AP*AP*CP*G)-3'), ...
著者Nikolova, E.N, Stanfield, R.L, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E.
登録日2017-04-28
公開日2018-04-04
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献CH···O Hydrogen Bonds Mediate Highly Specific Recognition of Methylated CpG Sites by the Zinc Finger Protein Kaiso.
Biochemistry, 57, 2018
5VMY
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BU of 5vmy by Molmil
Kaiso (ZBTB33) zinc finger DNA binding domain in complex with a hemi CpG-methylated DNA resembling the specific Kaiso binding sequence (KBS)
分子名称: CHLORIDE ION, DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*CP*GP*CP*GP*GP*GP*AP*AP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*CP*CP*(5CM)P*GP*(5CM)P*GP*AP*AP*TP*AP*AP*CP*G)-3'), ...
著者Nikolova, E.N, Stanfield, R.L, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E.
登録日2017-04-28
公開日2018-04-04
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.002 Å)
主引用文献CH···O Hydrogen Bonds Mediate Highly Specific Recognition of Methylated CpG Sites by the Zinc Finger Protein Kaiso.
Biochemistry, 57, 2018
5U7G
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BU of 5u7g by Molmil
Crystal Structure of the Catalytic Core of CBP
分子名称: CREB-binding protein, ZINC ION
著者Park, S, Stanfield, R.L, Martinez-Yamout, M.M, Dyson, H.J, Wilson, I.A, Wright, P.E.
登録日2016-12-12
公開日2017-06-21
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.401 Å)
主引用文献Role of the CBP catalytic core in intramolecular SUMOylation and control of histone H3 acetylation.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017

 

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