2CV8
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2CSO
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2CU1
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2CZ9
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![BU of 2cz9 by Molmil](/molmil-images/mine/2cz9) | Crystal Structure of galactokinase from Pyrococcus horikoshi | 分子名称: | CHLORIDE ION, GLYCEROL, Probable galactokinase | 著者 | Inagaki, E, Sakamoto, K, Shinkai, A, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2005-07-12 | 公開日 | 2006-09-26 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Crystal Structure of galactokinase from Pyrococcus horikoshi To be Published
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2CXA
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![BU of 2cxa by Molmil](/molmil-images/mine/2cxa) | Crystal structure of Leucyl/phenylalanyl-tRNA protein transferase from Escherichia coli | 分子名称: | Leucyl/phenylalanyl-tRNA-protein transferase | 著者 | Kato-Murayama, M, Bessho, Y, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2005-06-28 | 公開日 | 2005-12-28 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | The crystal structure of leucyl/phenylalanyl-tRNA-protein transferase from Escherichia coli Protein Sci., 16, 2007
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2CYY
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![BU of 2cyy by Molmil](/molmil-images/mine/2cyy) | Crystal structure of PH1519 from Pyrococcus horikosii OT3 | 分子名称: | CALCIUM ION, GLUTAMINE, Putative HTH-type transcriptional regulator PH1519 | 著者 | Okazaki, N, Nakano, N, Shinkai, A, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2005-07-08 | 公開日 | 2006-09-19 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of PH1519 from Pyrococcus horikosii OT3 To be Published
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6ACR
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![BU of 6acr by Molmil](/molmil-images/mine/6acr) | Crystal structure of human ALK2 kinase domain with R206H mutation in complex with RK-59638 | 分子名称: | Activin receptor type-1, N-(4-methoxyphenyl)-4-[3-(pyridin-3-yl)-1H-pyrazol-4-yl]pyrimidin-2-amine, SULFATE ION | 著者 | Sakai, N, Mishima-Tsumagari, C, Matsumoto, T, Shirouzu, M. | 登録日 | 2018-07-27 | 公開日 | 2019-03-20 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Bis-Heteroaryl Pyrazoles: Identification of Orally Bioavailable Inhibitors of Activin Receptor-Like Kinase-2 (R206H). Chem. Pharm. Bull., 67, 2019
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4Z16
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![BU of 4z16 by Molmil](/molmil-images/mine/4z16) | Crystal Structure of the Jak3 Kinase Domain Covalently Bound to N-(3-(((5-chloro-2-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)amino)methyl)phenyl)acrylamide | 分子名称: | N-(3-{[(5-chloro-2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino]methyl}phenyl)prop-2-enamide, Tyrosine-protein kinase JAK3 | 著者 | McNally, R, Tan, L, Gray, N.S, Eck, M.J. | 登録日 | 2015-03-26 | 公開日 | 2016-02-10 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Development of Selective Covalent Janus Kinase 3 Inhibitors. J.Med.Chem., 58, 2015
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6JUX
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![BU of 6jux by Molmil](/molmil-images/mine/6jux) | Crystal structure of human ALK2 kinase domain with R206H mutation in complex with RK-71807 | 分子名称: | 4-(1-ethyl-3-pyridin-3-yl-pyrazol-4-yl)-~{N}-(4-piperazin-1-ylphenyl)pyrimidin-2-amine, Activin receptor type-1, SULFATE ION | 著者 | Sakai, N, Mishima-Tsumagari, C, Matsumoto, T, Shirouzu, M. | 登録日 | 2019-04-15 | 公開日 | 2020-04-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structural Basis of Activin Receptor-Like Kinase 2 (R206H) Inhibition by Bis-heteroaryl Pyrazole-Based Inhibitors for the Treatment of Fibrodysplasia Ossificans Progressiva Identified by the Integration of Ligand-Based and Structure-Based Drug Design Approaches. Acs Omega, 5, 2020
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1RKR
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![BU of 1rkr by Molmil](/molmil-images/mine/1rkr) | CRYSTAL STRUCTURE OF AZURIN-I FROM ALCALIGENES XYLOSOXIDANS NCIMB 11015 | 分子名称: | AZURIN-I, COPPER (II) ION | 著者 | Li, C, Inoue, T, Gotowda, M, Suzuki, S, Yamaguchi, K, Kataoka, K, Kai, Y. | 登録日 | 1997-05-17 | 公開日 | 1998-05-20 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Structure of azurin I from the denitrifying bacterium Alcaligenes xylosoxidans NCIMB 11015 at 2.45 A resolution. Acta Crystallogr.,Sect.D, 54, 1998
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5VUB
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![BU of 5vub by Molmil](/molmil-images/mine/5vub) | Pim1 Kinase in complex with a benzofuranone inhibitor | 分子名称: | (2Z)-6-methoxy-7-(piperazin-1-ylmethyl)-2-(1H-pyrrolo[3,2-b]pyridin-3-ylmethylidene)-1-benzofuran-3-one, GLYCEROL, Serine/threonine-protein kinase pim-1 | 著者 | Parker, L.J. | 登録日 | 2017-05-18 | 公開日 | 2017-12-13 | 最終更新日 | 2018-01-17 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Theoretical Analysis of Activity Cliffs among Benzofuranone-Class Pim1 Inhibitors Using the Fragment Molecular Orbital Method with Molecular Mechanics Poisson-Boltzmann Surface Area (FMO+MM-PBSA) Approach J Chem Inf Model, 57, 2017
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2GS9
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![BU of 2gs9 by Molmil](/molmil-images/mine/2gs9) | Crystal structure of TT1324 from Thermus thermophilis HB8 | 分子名称: | FORMIC ACID, Hypothetical protein TT1324, S-ADENOSYL-L-HOMOCYSTEINE | 著者 | Kamitori, S, Abe, A, Ebihara, A, Kanagawa, M, Nakagawa, N, Kuroishi, C, Agari, Y, Kuramitsu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2006-04-25 | 公開日 | 2007-03-13 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal structure of TT1324 from Thermus thermophilis HB8 To be Published
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1E7Z
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![BU of 1e7z by Molmil](/molmil-images/mine/1e7z) | Crystal structure of the EMAP2/RNA binding domain of the p43 protein from human aminoacyl-tRNA synthetase complex | 分子名称: | ENDOTHELIAL-MONOCYTE ACTIVATING POLYPEPTIDE II, MERCURY (II) ION | 著者 | Pasqualato, S, Kerjan, P, Renault, L, Menetrey, J, Mirande, M, Cherfils, J. | 登録日 | 2000-09-13 | 公開日 | 2000-11-27 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Structure of the Emapii Domain of Human Aminoacyl-tRNA Synthetase Complex Reveals Evolutionary Dimeric Mimicry Embo J., 20, 2001
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7DEV
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![BU of 7dev by Molmil](/molmil-images/mine/7dev) | Crystal Structures of Anthocyanin 5,3'-aromatic acyltransferase from Gentiana triflora | 分子名称: | Anthocyanin 5-aromatic acyltransferase | 著者 | Murayama, K, Kato-Murayama, M, Shirouzu, M. | 登録日 | 2020-11-05 | 公開日 | 2021-09-15 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Anthocyanin 5,3'-aromatic acyltransferase from Gentiana triflora, a structural insight into biosynthesis of a blue anthocyanin. Phytochemistry, 186, 2021
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7DEX
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![BU of 7dex by Molmil](/molmil-images/mine/7dex) | Crystal Structures of Anthocyanin 5,3'-aromatic acyltransferase H174A mutant with caffeoyl-CoA | 分子名称: | Anthocyanin 5-aromatic acyltransferase, S-[2-[3-[[(2R)-4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethyl] (E)-3-[3,4-bis(oxidanyl)phenyl]prop-2-enethioate | 著者 | Murayama, K, Kato-Murayama, M, Shirouzu, M. | 登録日 | 2020-11-05 | 公開日 | 2021-09-15 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Anthocyanin 5,3'-aromatic acyltransferase from Gentiana triflora, a structural insight into biosynthesis of a blue anthocyanin. Phytochemistry, 186, 2021
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5K7X
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5XON
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![BU of 5xon by Molmil](/molmil-images/mine/5xon) | RNA Polymerase II elongation complex bound with Spt4/5 and TFIIS | 分子名称: | DNA (48-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... | 著者 | Ehara, H, Yokoyama, T, Shigematsu, H, Shirouzu, M, Sekine, S. | 登録日 | 2017-05-29 | 公開日 | 2017-08-16 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.83 Å) | 主引用文献 | Structure of the complete elongation complex of RNA polymerase II with basal factors Science, 357, 2017
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2YVQ
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![BU of 2yvq by Molmil](/molmil-images/mine/2yvq) | Crystal structure of MGS domain of carbamoyl-phosphate synthetase from homo sapiens | 分子名称: | Carbamoyl-phosphate synthase | 著者 | Xie, Y, Ihsanawati, Kishishita, S, Murayama, K, Takemoto, C, Shirozu, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-04-13 | 公開日 | 2008-04-15 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Crystal structure of MGS domain of carbamoyl-phosphate synthetase from homo sapiens To be Published
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3P0B
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4E1B
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![BU of 4e1b by Molmil](/molmil-images/mine/4e1b) | Re-refinement of PDB entry 2EQA - SUA5 protein from Sulfolobus tokodaii with bound threonylcarbamoyladenylate | 分子名称: | MAGNESIUM ION, YrdC/Sua5 family protein, threonylcarbamoyladenylate | 著者 | Parthier, C, Goerlich, S, Jaenecke, F, Breithaupt, C, Braeuer, U, Fandrich, U, Clausnitzer, D, Wehmeier, U.F, Boettcher, C, Scheel, D, Stubbs, M.T. | 登録日 | 2012-03-06 | 公開日 | 2012-03-14 | 最終更新日 | 2012-05-02 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The O-Carbamoyltransferase TobZ Catalyzes an Ancient Enzymatic Reaction. Angew.Chem.Int.Ed.Engl., 51, 2012
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5VUA
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![BU of 5vua by Molmil](/molmil-images/mine/5vua) | Pim1 Kinase in complex with a benzofuranone inhibitor | 分子名称: | (2Z)-6-methoxy-7-(piperazin-1-ylmethyl)-2-(1H-pyrrolo[2,3-c]pyridin-3-ylmethylidene)-1-benzofuran-3-one, GLYCEROL, PHOSPHATE ION, ... | 著者 | Parker, L.J. | 登録日 | 2017-05-18 | 公開日 | 2017-12-13 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Theoretical Analysis of Activity Cliffs among Benzofuranone-Class Pim1 Inhibitors Using the Fragment Molecular Orbital Method with Molecular Mechanics Poisson-Boltzmann Surface Area (FMO+MM-PBSA) Approach J Chem Inf Model, 57, 2017
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5VUC
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![BU of 5vuc by Molmil](/molmil-images/mine/5vuc) | Pim1 Kinase in complex with a benzofuranone inhibitor | 分子名称: | (2Z)-2-(1H-indol-3-ylmethylidene)-6-methoxy-7-(piperazin-1-ylmethyl)-1-benzofuran-3-one, GLYCEROL, Serine/threonine-protein kinase pim-1 | 著者 | Parker, L.J. | 登録日 | 2017-05-18 | 公開日 | 2017-12-13 | 最終更新日 | 2018-01-17 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Theoretical Analysis of Activity Cliffs among Benzofuranone-Class Pim1 Inhibitors Using the Fragment Molecular Orbital Method with Molecular Mechanics Poisson-Boltzmann Surface Area (FMO+MM-PBSA) Approach J Chem Inf Model, 57, 2017
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2YRW
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![BU of 2yrw by Molmil](/molmil-images/mine/2yrw) | Crystal structure of GAR synthetase from Geobacillus kaustophilus | 分子名称: | PHOSPHATE ION, Phosphoribosylglycinamide synthetase | 著者 | Baba, S, Kanagawa, M, Kuramitsu, S, Yokoyama, S, Kawai, G, Sampei, G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-04-03 | 公開日 | 2007-10-09 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structures of glycinamide ribonucleotide synthetase, PurD, from thermophilic eubacteria J.Biochem., 148, 2010
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2YS6
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![BU of 2ys6 by Molmil](/molmil-images/mine/2ys6) | Crystal structure of GAR synthetase from Geobacillus kaustophilus | 分子名称: | ADENOSINE MONOPHOSPHATE, GLYCINE, Phosphoribosylglycinamide synthetase | 著者 | Baba, S, Kanagawa, M, Kuramitsu, S, Yokoyama, S, Kawai, G, Sampei, G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-04-03 | 公開日 | 2007-10-09 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Crystal structures of glycinamide ribonucleotide synthetase, PurD, from thermophilic eubacteria J.Biochem., 148, 2010
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2YS7
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![BU of 2ys7 by Molmil](/molmil-images/mine/2ys7) | Crystal structure of GAR synthetase from Geobacillus kaustophilus | 分子名称: | Phosphoribosylglycinamide synthetase | 著者 | Baba, S, Kanagawa, M, Kuramitsu, S, Yokoyama, S, Kawai, G, Sampei, G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-04-03 | 公開日 | 2007-10-09 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Crystal structures of glycinamide ribonucleotide synthetase, PurD, from thermophilic eubacteria J.Biochem., 148, 2010
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