4POK
 
 | | Crystal structures of thioredoxin with mesna at 2.5A resolution | | 分子名称: | 1-THIOETHANESULFONIC ACID, Thioredoxin | | 著者 | Sridhar, V, Chie-Leon, B, Badger, J, Nienaber, V.L, Hausheer, F.H. | | 登録日 | 2014-02-25 | | 公開日 | 2014-10-29 | | 最終更新日 | 2024-11-27 | | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | | 主引用文献 | BNP7787 Forms Novel Covalent
Adducts on Human Thioredoxin
and Modulates Thioredoxin
Activity
J Pharmacol Clin Toxicol, 2, 2014
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4POM
 | | Crystal structures of thioredoxin with mesna at 1.85A resolution | | 分子名称: | 1-THIOETHANESULFONIC ACID, Thioredoxin | | 著者 | Sridhar, V, Chie-Leon, B, Badger, J, Nienaber, V.L, Hausheer, F.H. | | 登録日 | 2014-02-26 | | 公開日 | 2014-10-29 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | BNP7787 Forms Novel Covalent
Adducts on Human Thioredoxin
and Modulates Thioredoxin
Activity
J Pharmacol Clin Toxicol, 2, 2014
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6M6B
 | | Cryo-EM structure of Thermus thermophilus Mfd in complex with RNA polymerase and ATP-gamma-S | | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | 著者 | Shi, J, Wen, A, Feng, Y. | | 登録日 | 2020-03-14 | | 公開日 | 2020-10-14 | | 最終更新日 | 2025-06-18 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Structural basis of Mfd-dependent transcription termination.
Nucleic Acids Res., 48, 2020
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4TT7
 | | Crystal structure of human ALK with a covalent modification | | 分子名称: | 1,2-ETHANEDIOL, 1-THIOETHANESULFONIC ACID, ALK tyrosine kinase receptor | | 著者 | Badger, J, Sridhar, V, Chie-Leon, B, Nienaber, V.L, Hausheer, F.H. | | 登録日 | 2014-06-19 | | 公開日 | 2015-02-11 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Novel covalent modification of human anaplastic lymphoma kinase (ALK) and potentiation of crizotinib-mediated inhibition of ALK activity by BNP7787.
Onco Targets Ther, 8, 2015
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4POL
 | | Crystal structures of thioredoxin with mesna at 2.8A resolution | | 分子名称: | 1-THIOETHANESULFONIC ACID, Thioredoxin | | 著者 | Sridhar, V, Chie-Leon, B, Badger, J, Nienaber, V.L, Hausheer, F.H. | | 登録日 | 2014-02-26 | | 公開日 | 2014-10-29 | | 最終更新日 | 2024-11-27 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | BNP7787 Forms Novel Covalent
Adducts on Human Thioredoxin
and Modulates Thioredoxin
Activity
J Pharmacol Clin Toxicol, 2, 2014
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4MWR
 | | Anhui N9-zanamivir | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neuraminidase, ... | | 著者 | Wu, Y, Qi, J.X, Gao, F, Gao, G.F. | | 登録日 | 2013-09-25 | | 公開日 | 2013-11-20 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.797 Å) | | 主引用文献 | Characterization of two distinct neuraminidases from avian-origin human-infecting H7N9 influenza viruses
Cell Res., 23, 2013
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4MWX
 | | Shanghai N9-zanamivir | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neuraminidase, ... | | 著者 | Wu, Y, Qi, J.X, Gao, F, Gao, G.F. | | 登録日 | 2013-09-25 | | 公開日 | 2013-11-20 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.801 Å) | | 主引用文献 | Characterization of two distinct neuraminidases from avian-origin human-infecting H7N9 influenza viruses
Cell Res., 23, 2013
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4MWJ
 | | Anhui N9 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neuraminidase, ... | | 著者 | Wu, Y, Qi, J.X, Gao, F, Gao, G.F. | | 登録日 | 2013-09-25 | | 公開日 | 2013-11-20 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Characterization of two distinct neuraminidases from avian-origin human-infecting H7N9 influenza viruses
Cell Res., 23, 2013
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4MWW
 | | Shanghai N9-oseltamivir carboxylate | | 分子名称: | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Wu, Y, Qi, J.X, Gao, F, Gao, G.F. | | 登録日 | 2013-09-25 | | 公開日 | 2013-11-20 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Characterization of two distinct neuraminidases from avian-origin human-infecting H7N9 influenza viruses
Cell Res., 23, 2013
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4MWQ
 | | Anhui N9-oseltamivir carboxylate | | 分子名称: | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Wu, Y, Qi, J.X, Gao, F, Gao, G.F. | | 登録日 | 2013-09-25 | | 公開日 | 2013-11-20 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Characterization of two distinct neuraminidases from avian-origin human-infecting H7N9 influenza viruses
Cell Res., 23, 2013
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4MWL
 | | Shanghai N9 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neuraminidase, ... | | 著者 | Wu, Y, Qi, J.X, Gao, F, Gao, G.F. | | 登録日 | 2013-09-25 | | 公開日 | 2013-11-20 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Characterization of two distinct neuraminidases from avian-origin human-infecting H7N9 influenza viruses
Cell Res., 23, 2013
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4MX0
 | | Shanghai N9-peramivir | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(1-ACETYLAMINO-2-ETHYL-BUTYL)-4-GUANIDINO-2-HYDROXY-CYCLOPENTANECARBOXYLIC ACID, CALCIUM ION, ... | | 著者 | Wu, Y, Qi, J.X, Gao, F, Gao, G.F. | | 登録日 | 2013-09-25 | | 公開日 | 2013-11-20 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.101 Å) | | 主引用文献 | Characterization of two distinct neuraminidases from avian-origin human-infecting H7N9 influenza viruses
Cell Res., 23, 2013
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4MWV
 | | Anhui N9-peramivir | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(1-ACETYLAMINO-2-ETHYL-BUTYL)-4-GUANIDINO-2-HYDROXY-CYCLOPENTANECARBOXYLIC ACID, CALCIUM ION, ... | | 著者 | Wu, Y, Qi, J.X, Gao, F, Gao, G.F. | | 登録日 | 2013-09-25 | | 公開日 | 2013-11-20 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Characterization of two distinct neuraminidases from avian-origin human-infecting H7N9 influenza viruses
Cell Res., 23, 2013
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4MWU
 | | Anhui N9-laninamivir | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-acetamido-2,6-anhydro-4-carbamimidamido-3,4,5-trideoxy-7-O-methyl-D-glycero-D-galacto-non-2-enonic acid, CALCIUM ION, ... | | 著者 | Wu, Y, Qi, J.X, Gao, F, Gao, G.F. | | 登録日 | 2013-09-25 | | 公開日 | 2013-11-20 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.799 Å) | | 主引用文献 | Characterization of two distinct neuraminidases from avian-origin human-infecting H7N9 influenza viruses
Cell Res., 23, 2013
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5GSX
 | | Mouse MHC class I H-2Kd with a MERS-CoV-derived peptide 142-2 | | 分子名称: | 10-mer peptide from Spike protein, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ... | | 著者 | Liu, K, Chai, Y, Qi, J, Tan, W, Liu, W.J, Gao, G.F. | | 登録日 | 2016-08-17 | | 公開日 | 2017-06-07 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Protective T Cell Responses Featured by Concordant Recognition of Middle East Respiratory Syndrome Coronavirus-Derived CD8+ T Cell Epitopes and Host MHC.
J. Immunol., 198, 2017
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4MWY
 | | Shanghai N9-laninamivir | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-acetamido-2,6-anhydro-4-carbamimidamido-3,4,5-trideoxy-7-O-methyl-D-glycero-D-galacto-non-2-enonic acid, CALCIUM ION, ... | | 著者 | Wu, Y, Qi, J.X, Gao, F, Gao, G.F. | | 登録日 | 2013-09-25 | | 公開日 | 2013-11-20 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Characterization of two distinct neuraminidases from avian-origin human-infecting H7N9 influenza viruses
Cell Res., 23, 2013
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9CLX
 | | Angiotensin I converting enzyme full-length dimer | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, ... | | 著者 | Mancl, J.M, Tang, W.J. | | 登録日 | 2024-07-12 | | 公開日 | 2025-06-18 | | 実験手法 | ELECTRON MICROSCOPY (3.65 Å) | | 主引用文献 | Dimerization and dynamics of angiotensin-I converting enzyme revealed by cryoEM and MD simulations
Elife, 2025
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9D5M
 | | Apo ACE full dimer 1 prepared by chameleon | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, ... | | 著者 | Mancl, J.M, Tang, W.J. | | 登録日 | 2024-08-13 | | 公開日 | 2025-06-18 | | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | | 主引用文献 | Dimerization and dynamics of angiotensin-I converting enzyme revealed by cryoEM and MD simulations
Elife, 2025
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9D55
 | | Apo ACE full dimer 2 prepared by chameleon | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, ... | | 著者 | Mancl, J.M, Tang, W.J. | | 登録日 | 2024-08-13 | | 公開日 | 2025-06-18 | | 実験手法 | ELECTRON MICROSCOPY (3.15 Å) | | 主引用文献 | Dimerization and dynamics of angiotensin-I converting enzyme revealed by cryoEM and MD simulations
Elife, 2025
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9D5S
 | | Apo ACE full dimer 3 prepared by chameleon | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, ... | | 著者 | Mancl, J.M, Tang, W.J. | | 登録日 | 2024-08-14 | | 公開日 | 2025-06-18 | | 実験手法 | ELECTRON MICROSCOPY (2.99 Å) | | 主引用文献 | Dimerization and dynamics of angiotensin-I converting enzyme revealed by cryoEM and MD simulations
Elife, 2025
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9JQT
 | | Structure of interleukin receptor common gamma chain (IL2Rgamma/CD132) in complex with 2D4 | | 分子名称: | 2D4-Heavy Chain, 2D4-Light Chain, Anti-Fab nanobody, ... | | 著者 | Lu, Q.J, Yin, H.Q. | | 登録日 | 2024-09-28 | | 公開日 | 2024-12-18 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | 2D4, a humanized monoclonal antibody targeting CD132, is a promising treatment for systemic lupus erythematosus.
Signal Transduct Target Ther, 9, 2024
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5K07
 | | Crystal structure of CREN7-DSDNA (GTAATTGC) complex | | 分子名称: | Chromatin protein Cren7, DNA (5'-D(*GP*TP*AP*AP*TP*TP*GP*C)-3') | | 著者 | Zhang, Z.F, Gong, Y. | | 登録日 | 2016-05-17 | | 公開日 | 2017-05-24 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Sequence-Dependent T:G Base Pair Opening in DNA Double Helix Bound by Cren7, a Chromatin Protein Conserved among Crenarchaea
PLoS ONE, 11, 2016
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5K17
 | | Crystal structure of CREN7-DSDNA (GTGATCGC) complex | | 分子名称: | Chromatin protein Cren7, DNA (5'-D(*GP*TP*GP*AP*TP*CP*GP*C)-3') | | 著者 | Zhang, Z.F, Gong, Y. | | 登録日 | 2016-05-17 | | 公開日 | 2017-05-24 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Sequence-Dependent T:G Base Pair Opening in DNA Double Helix Bound by Cren7, a Chromatin Protein Conserved among Crenarchaea
PLoS ONE, 11, 2016
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6XOW
 | |
6K4Y
 | | CryoEM structure of sigma appropriation complex | | 分子名称: | 10 kDa anti-sigma factor, DNA (60-MER), DNA-directed RNA polymerase subunit alpha, ... | | 著者 | Shi, J, Wen, A, Feng, Y. | | 登録日 | 2019-05-27 | | 公開日 | 2019-08-07 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.79 Å) | | 主引用文献 | Structural basis of sigma appropriation.
Nucleic Acids Res., 47, 2019
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