4MWQ

Anhui N9-oseltamivir carboxylate

Summary for 4MWQ

• Entry DOI: 10.2210/pdb4mwq/pdb
• Related: 4MWJ 4MWL 4MWR 4MWU 4MWV 4MWW 4MWX 4MWY 4MX0
• Descriptor: Neuraminidase, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• Functional Keywords: 6-bladed beta-propeller, hydrolase, glycosylation
• Biological source: Influenza A virus
• Cellular location: Host apical cell membrane ; Single-pass type II membrane protein : A0A024E3Q2
• Total number of polymer chains: 1
• Total formula weight: 45879.75

Authors

Wu, Y.,Qi, J.X.,Gao, F.,Gao, G.F. (deposition date: 2013-09-25, release date: 2013-11-20, Last modification date: 2020-07-29)

• Primary citation: Wu, Y.,Bi, Y.H.,Vavricka, C.J.,Sun, X.M.,Zhang, Y.F.,Gao, F.,Zhao, M.,Xiao, H.X.,Qin, C.F.,He, J.H.,Liu, W.J.,Yan, J.H.,Qi, J.X.,Gao, G.F.; Characterization of two distinct neuraminidases from avian-origin human-infecting H7N9 influenza viruses; Cell Res., 23:1347-1355, 2013; PubMed: 24165891; DOI: 10.1038/cr.2013.144

Experimental method

X-RAY DIFFRACTION (2 Å)