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6XKB
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Crystal structure of SR-related and CTD-associated factor 4(SCAF4-CID)with peptide S2,S5p-CTD
分子名称: S2,S5p-CTD peptide, SR-related and CTD-associated factor 4, UNKNOWN ATOM OR ION
著者Zhou, M.Q, Dong, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2020-06-26
公開日2021-01-20
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural basis for the recognition of the S2, S5-phosphorylated RNA polymerase II CTD by the mRNA anti-terminator protein hSCAF4.
Febs Lett., 596, 2022
7RRD
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IDO1 IN COMPLEX WITH COMPOUND S-1
分子名称: 3-[4-(1H-benzimidazol-2-yl)phenyl]-N-(4-fluorophenyl)oxetane-3-carboxamide, Indoleamine 2,3-dioxygenase 1
著者Lesburg, C.A.
登録日2021-08-09
公開日2022-08-24
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献Oxetane promise delivered: discovery of long acting IDO1 inhibitors suitable for Q3W oral or parenteral dosing
To Be Published
5CMZ
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BU of 5cmz by Molmil
Artificial HIV fusion inhibitor AP3 fused to the C-terminus of gp41 NHR
分子名称: 1,2-ETHANEDIOL, 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, Artificial HIV entry inhibitor AP3, ...
著者Zhu, Y, Ye, S, Zhang, R.
登録日2015-07-17
公開日2015-09-16
実験手法X-RAY DIFFRACTION (2.574 Å)
主引用文献Improved Pharmacological and Structural Properties of HIV Fusion Inhibitor AP3 over Enfuvirtide: Highlighting Advantages of Artificial Peptide Strategy.
Sci Rep, 5, 2015
5CN0
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BU of 5cn0 by Molmil
Artificial HIV fusion inhibitor AP2 fused to the C-terminus of gp41 NHR
分子名称: DI(HYDROXYETHYL)ETHER, Envelope glycoprotein,AP2, MAGNESIUM ION
著者Zhu, Y, Ye, S, Zhang, R.
登録日2015-07-17
公開日2015-09-16
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.901 Å)
主引用文献Improved Pharmacological and Structural Properties of HIV Fusion Inhibitor AP3 over Enfuvirtide: Highlighting Advantages of Artificial Peptide Strategy.
Sci Rep, 5, 2015
5CMU
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BU of 5cmu by Molmil
Artificial HIV fusion inhibitor AP1 fused to the C-terminus of gp41 NHR
分子名称: Envelope glycoprotein,AP1, GLYCEROL
著者Zhu, Y, Ye, S, Zhang, R.
登録日2015-07-17
公開日2015-09-16
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.113 Å)
主引用文献Improved Pharmacological and Structural Properties of HIV Fusion Inhibitor AP3 over Enfuvirtide: Highlighting Advantages of Artificial Peptide Strategy.
Sci Rep, 5, 2015
6OGK
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MeCP2 MBD in complex with DNA
分子名称: CALCIUM ION, DNA (5'-D(*CP*GP*GP*AP*GP*TP*GP*TP*AP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*TP*AP*(5CM)P*AP*CP*TP*CP*CP*G)-3'), ...
著者Lei, M, Tempel, W, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium, Structural Genomics Consortium (SGC)
登録日2019-04-02
公開日2019-05-01
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Plasticity at the DNA recognition site of the MeCP2 mCG-binding domain.
Biochim Biophys Acta Gene Regul Mech, 1862, 2019
6OGJ
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MeCP2 MBD in complex with DNA
分子名称: DNA (5'-D(*CP*GP*GP*AP*GP*TP*GP*TP*AP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*TP*AP*CP*AP*CP*TP*CP*CP*G)-3'), Methyl-CpG-binding protein 2, ...
著者Lei, M, Tempel, W, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2019-04-02
公開日2019-05-01
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Plasticity at the DNA recognition site of the MeCP2 mCG-binding domain.
Biochim Biophys Acta Gene Regul Mech, 1862, 2019
5WSH
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Structure of HLA-A2 P130
分子名称: Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, GLY-VAL-TRP-ILE-ARG-THR-PRO-THR-ALA, ...
著者Zhang, Y, Wu, Y, Qi, J, Liu, J, Gao, G.F, Meng, S.
登録日2016-12-07
公開日2017-12-20
最終更新日2019-01-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献CD8+T-Cell Response-Associated Evolution of Hepatitis B Virus Core Protein and Disease Progress.
J. Virol., 92, 2018
5H36
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Crystal structures of the TRIC trimeric intracellular cation channel orthologue from Rhodobacter sphaeroides
分子名称: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Uncharacterized protein TRIC
著者Kasuya, G, Hiraizumi, M, Hattori, M, Nureki, O.
登録日2016-10-20
公開日2017-01-11
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (3.409 Å)
主引用文献Crystal structures of the TRIC trimeric intracellular cation channel orthologues
Cell Res., 26, 2016
7EDO
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BU of 7edo by Molmil
First insight into marsupial MHC I peptide presentation: immune features of lower mammals paralleled with bats
分子名称: Beta-2-microglobulin, CYS-ASN-VAL-THR-LEU-ASN-TYR-PRO, MHC class I antigen
著者Wang, P.Y, Yue, C, Lu, D, Liu, K.F, Liu, S, Yao, S.J, Chai, Y, Qi, J.X, Lou, Y.L, Sun, Z.Y, Gao, G.F, Liu, W.J.
登録日2021-03-16
公開日2021-08-11
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Peptide Presentations of Marsupial MHC Class I Visualize Immune Features of Lower Mammals Paralleled with Bats.
J Immunol., 207, 2021
4O46
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14-3-3-gamma in complex with influenza NS1 C-terminal tail phosphorylated at S228
分子名称: 14-3-3 protein gamma, Nonstructural protein 1, UNKNOWN ATOM OR ION, ...
著者Qin, S, Liu, Y, Tempel, W, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2013-12-18
公開日2014-04-30
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis for histone mimicry and hijacking of host proteins by influenza virus protein NS1.
Nat Commun, 5, 2014
7E0B
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BU of 7e0b by Molmil
The crystal structure of sorting nexin 27 and PBM complex
分子名称: PBM, Sorting nexin-27
著者Shang, G.J, Qi, J.X.
登録日2021-01-27
公開日2022-02-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.29 Å)
主引用文献SNX27 suppresses SARS-CoV-2 infection by inhibiting viral lysosome/late endosome entry.
Proc.Natl.Acad.Sci.USA, 119, 2022
7JZI
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Crystal structure of LAIR1 ectodomain (from MGD21) in complex with Plasmodium RIFIN (PF3D7_1040300) V2 domain
分子名称: LAIR1 ectodomain from antibody MGD21, PLATINUM (II) ION, Rifin
著者Xu, K, Kwong, P.D.
登録日2020-09-02
公開日2021-05-26
最終更新日2021-09-22
実験手法X-RAY DIFFRACTION (2.707 Å)
主引用文献Structural basis of LAIR1 targeting by polymorphic Plasmodium RIFINs.
Nat Commun, 12, 2021
7JZ4
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Crystal structure of broadly Plasmodium RIFIN reactive LAIR1-inserted antibody MGD21
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, MGD21 heavy chain, MGD21 light chain, ...
著者Xu, K, Kwong, P.D.
登録日2020-09-01
公開日2021-05-26
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.747 Å)
主引用文献Structural basis of LAIR1 targeting by polymorphic Plasmodium RIFINs.
Nat Commun, 12, 2021
7JZK
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BU of 7jzk by Molmil
Crystal structure of LAIR1 ectodomain (from MGD21) in complex with Plasmodium RIFIN (PF3D7_0401300) V2 domain
分子名称: LAIR1 ecotodomain from MGD21 antibody, Rifin, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Xu, K, Kwong, P.D.
登録日2020-09-02
公開日2021-05-26
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.457 Å)
主引用文献Structural basis of LAIR1 targeting by polymorphic Plasmodium RIFINs.
Nat Commun, 12, 2021
7JZ1
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Crystal structure of broadly Plasmodium RIFIN reactive LAIR1-inserted antibody MGC34
分子名称: MGC34 heavy chain, MGC34 light chain
著者Xu, K, Kwong, P.D.
登録日2020-09-01
公開日2021-05-26
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.37 Å)
主引用文献Structural basis of LAIR1 targeting by polymorphic Plasmodium RIFINs.
Nat Commun, 12, 2021
8KA8
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BU of 8ka8 by Molmil
Cryo-EM structure of SARS-CoV-2 Delta RBD in complex with golden hamster ACE2 (local refinement)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, ...
著者Niu, S, Zhao, Z.N, Chai, Y, Gao, G.F.
登録日2023-08-02
公開日2024-01-31
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (2.96 Å)
主引用文献Structural basis and analysis of hamster ACE2 binding to different SARS-CoV-2 spike RBDs.
J.Virol., 98, 2024
8KC2
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BU of 8kc2 by Molmil
Cryo-EM structure of SARS-CoV-2 BA.3 RBD in complex with golden hamster ACE2 (local refinement)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, ...
著者Niu, S, Zhao, Z.N, Chai, Y, Gao, G.F.
登録日2023-08-05
公開日2024-01-31
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structural basis and analysis of hamster ACE2 binding to different SARS-CoV-2 spike RBDs.
J.Virol., 98, 2024
7WBL
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BU of 7wbl by Molmil
Cryo-EM structure of human ACE2 complexed with SARS-CoV-2 Omicron RBD
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike protein S1, ...
著者Liu, S, Gao, F.G.
登録日2021-12-17
公開日2022-01-19
最終更新日2022-03-02
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Receptor binding and complex structures of human ACE2 to spike RBD from omicron and delta SARS-CoV-2.
Cell, 185, 2022
8J7W
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BU of 8j7w by Molmil
Cryo-EM structure of hZnT7-Fab complex in zinc state 2, determined in heterogeneous conformations- one subunit in an inward-facing zinc-bound and the other in an outward-facing zinc-bound conformation
分子名称: Heavy chain of YN7114-08 Fab, Light chain of YN7114-08 Fab, ZINC ION, ...
著者Han, B.B, Inaba, K, Watanabe, S.
登録日2023-04-28
公開日2023-09-20
実験手法ELECTRON MICROSCOPY (2.92 Å)
主引用文献Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn 2+ uptake into the Golgi apparatus.
Nat Commun, 14, 2023
8J7X
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Cryo-EM structure of hZnT7DeltaHis-loop-Fab complex in zinc-unbound state, determined in outward-facing conformation
分子名称: Heavy chain of YN7114-08 Fab, Light chain of YN7114-08 Fab, Zinc transporter 7
著者Han, B.B, Inaba, K, Watanabe, S.
登録日2023-04-28
公開日2023-09-20
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn 2+ uptake into the Golgi apparatus.
Nat Commun, 14, 2023
8J7V
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BU of 8j7v by Molmil
Cryo-EM structure of hZnT7-Fab complex in zinc-unbound state, determined in heterogeneous conformations- one subunit in an inward-facing and the other in an outward-facing conformation
分子名称: Heavy chain of YN7114-08 Fab, Light chain of YN7114-08 Fab, Zinc transporter 7
著者Han, B.B, Inaba, K, Watanabe, S.
登録日2023-04-28
公開日2023-09-20
実験手法ELECTRON MICROSCOPY (2.79 Å)
主引用文献Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn 2+ uptake into the Golgi apparatus.
Nat Commun, 14, 2023
8J7U
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BU of 8j7u by Molmil
Cryo-EM structure of hZnT7-Fab complex in zinc-bound state, determined in outward-facing conformation
分子名称: Heavy chain of YN7114-08 Fab, Light chain of YN7114-08 Fab, ZINC ION, ...
著者Han, B.B, Inaba, K, Watanabe, S.
登録日2023-04-28
公開日2023-09-20
実験手法ELECTRON MICROSCOPY (3.12 Å)
主引用文献Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn 2+ uptake into the Golgi apparatus.
Nat Commun, 14, 2023
8J80
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Cryo-EM structure of hZnT7-Fab complex in zinc state 1, determined in heterogeneous conformations- one subunit in an inward-facing zinc-bound and the other in an outward-facing zinc-unbound conformation
分子名称: Heavy chain of YN7114-08 Fab, Light chain of YN7114-08 Fab, ZINC ION, ...
著者Han, B.B, Inaba, K, Watanabe, S.
登録日2023-04-28
公開日2023-09-20
実験手法ELECTRON MICROSCOPY (2.68 Å)
主引用文献Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn 2+ uptake into the Golgi apparatus.
Nat Commun, 14, 2023
8J7T
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BU of 8j7t by Molmil
Cryo-EM structure of hZnT7-Fab complex in zinc-unbound state, determined in outward-facing conformation
分子名称: Heavy chain of YN7114-08 Fab, Light chain of YN7114-08 Fab, Zinc transporter 7
著者Han, B.B, Inaba, K, Watanabe, S.
登録日2023-04-28
公開日2023-09-20
実験手法ELECTRON MICROSCOPY (2.2 Å)
主引用文献Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn 2+ uptake into the Golgi apparatus.
Nat Commun, 14, 2023

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