8E6K
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![BU of 8e6k by Molmil](/molmil-images/mine/8e6k) | 2H08 Fab in complex with influenza virus neuraminidase from A/Brevig Mission/1/1918 (H1N1) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2H08 fragment antigen binding heavy chain, 2H08 fragment antigen binding light chain, ... | 著者 | Turner, H.L, Ozorowski, G, Ward, A.B. | 登録日 | 2022-08-22 | 公開日 | 2023-08-09 | 最終更新日 | 2023-08-23 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Human anti-N1 monoclonal antibodies elicited by pandemic H1N1 virus infection broadly inhibit HxN1 viruses in vitro and in vivo. Immunity, 56, 2023
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8E6J
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6CYV
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![BU of 6cyv by Molmil](/molmil-images/mine/6cyv) | E. coli DHFR ternary complex with NADP and dihydrofolate | 分子名称: | DIHYDROFOLIC ACID, Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Cao, H, Rodrigues, J, Benach, J, Frommelt, A, Morisco, L, Koss, J, Shakhnovich, E, Skolnick, J. | 登録日 | 2018-04-06 | 公開日 | 2019-01-09 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | The crystal structure of a tetrahydrofolate-bound dihydrofolate reductase reveals the origin of slow product release. Commun Biol, 1, 2018
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6CXK
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![BU of 6cxk by Molmil](/molmil-images/mine/6cxk) | E. coli DHFR substrate complex with Dihydrofolate | 分子名称: | CHLORIDE ION, DIHYDROFOLIC ACID, Dihydrofolate reductase, ... | 著者 | Cao, H, Rodrigues, J, Benach, J, Frommelt, A, Morisco, L, Koss, J, Shakhnovich, E, Skolnick, J. | 登録日 | 2018-04-03 | 公開日 | 2019-01-09 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.108 Å) | 主引用文献 | The crystal structure of a tetrahydrofolate-bound dihydrofolate reductase reveals the origin of slow product release. Commun Biol, 1, 2018
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4HGZ
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![BU of 4hgz by Molmil](/molmil-images/mine/4hgz) | Structure of the CcbJ Methyltransferase from Streptomyces caelestis | 分子名称: | 1,2-ETHANEDIOL, CcbJ, LITHIUM ION, ... | 著者 | Bauer, J.A, Ondrovicova, G, Kutejova, E, Janata, J. | 登録日 | 2012-10-09 | 公開日 | 2013-10-30 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structure and possible mechanism of the CcbJ methyltransferase from Streptomyces caelestis. Acta Crystallogr.,Sect.D, 70, 2014
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8EQA
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8EQC
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4HGY
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![BU of 4hgy by Molmil](/molmil-images/mine/4hgy) | Structure of the CcbJ Methyltransferase from Streptomyces caelestis | 分子名称: | 1,2-ETHANEDIOL, CcbJ, SULFATE ION | 著者 | Bauer, J.A, Ondrovicova, G, Kutejova, E, Janata, J. | 登録日 | 2012-10-09 | 公開日 | 2013-10-30 | 最終更新日 | 2014-04-16 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structure and possible mechanism of the CcbJ methyltransferase from Streptomyces caelestis. Acta Crystallogr.,Sect.D, 70, 2014
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4HH4
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![BU of 4hh4 by Molmil](/molmil-images/mine/4hh4) | Structure of the CcbJ Methyltransferase from Streptomyces caelestis | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CcbJ, GLYCEROL, ... | 著者 | Bauer, J.A, Ondrovicova, G, Kutejova, E, Janata, J. | 登録日 | 2012-10-09 | 公開日 | 2013-10-30 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structure and possible mechanism of the CcbJ methyltransferase from Streptomyces caelestis. Acta Crystallogr.,Sect.D, 70, 2014
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7TBI
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![BU of 7tbi by Molmil](/molmil-images/mine/7tbi) | Composite structure of the S. cerevisiae nuclear pore complex (NPC) | 分子名称: | Dyn2, Nic96 R1, Nic96 R2, ... | 著者 | Petrovic, S, Samanta, D, Perriches, T, Bley, C.J, Thierbach, K, Brown, B, Nie, S, Mobbs, G.W, Stevens, T.A, Liu, X, Tomaleri, G.P, Schaus, L, Hoelz, A. | 登録日 | 2021-12-22 | 公開日 | 2022-06-15 | 最終更新日 | 2022-06-22 | 実験手法 | ELECTRON MICROSCOPY (25 Å) | 主引用文献 | Architecture of the linker-scaffold in the nuclear pore. Science, 376, 2022
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5WY8
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![BU of 5wy8 by Molmil](/molmil-images/mine/5wy8) | Crystal structure of PTP delta Ig1-Ig3 in complex with IL1RAPL1 Ig1-Ig3 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-1 receptor accessory protein-like 1, ... | 著者 | Kim, H.M, Won, S.Y, Kim, D. | 登録日 | 2017-01-11 | 公開日 | 2017-11-22 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.07 Å) | 主引用文献 | LAR-RPTP Clustering Is Modulated by Competitive Binding between Synaptic Adhesion Partners and Heparan Sulfate Front Mol Neurosci, 10, 2017
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8OU4
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![BU of 8ou4 by Molmil](/molmil-images/mine/8ou4) | Cereblon isoform 4 in complex with novel Benzamide-Type Cereblon Binder 11a | 分子名称: | 4-azanyl-~{N}-[(3~{S})-2,6-bis(oxidanylidene)piperidin-3-yl]-2-chloranyl-benzamide, Cereblon isoform 4, ZINC ION | 著者 | Heim, C, Bischof, L, Hartmann, M.D. | 登録日 | 2023-04-21 | 公開日 | 2023-11-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Leveraging Ligand Affinity and Properties: Discovery of Novel Benzamide-Type Cereblon Binders for the Design of PROTACs. J.Med.Chem., 66, 2023
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8OU3
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![BU of 8ou3 by Molmil](/molmil-images/mine/8ou3) | Cereblon isoform 4 in complex with novel Benzamide-Type Cereblon Binder 8d | 分子名称: | 4-azanyl-~{N}-[(3~{S})-2,6-bis(oxidanylidene)piperidin-3-yl]-2-fluoranyl-benzamide, Cereblon isoform 4, PHOSPHATE ION, ... | 著者 | Heim, C, Bischof, L, Maiwald, S, Hartmann, M.D. | 登録日 | 2023-04-21 | 公開日 | 2023-11-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | 主引用文献 | Leveraging Ligand Affinity and Properties: Discovery of Novel Benzamide-Type Cereblon Binders for the Design of PROTACs. J.Med.Chem., 66, 2023
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8OU6
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![BU of 8ou6 by Molmil](/molmil-images/mine/8ou6) | Cereblon isoform 4 in complex with novel Benzamide-Type Cereblon Binder 11c | 分子名称: | 4-azanyl-~{N}-[(3~{S})-2,6-bis(oxidanylidene)piperidin-3-yl]-2-methyl-benzamide, Cereblon isoform 4, PHOSPHATE ION, ... | 著者 | Heim, C, Bischof, L, Hartmann, M.D. | 登録日 | 2023-04-21 | 公開日 | 2023-11-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | Leveraging Ligand Affinity and Properties: Discovery of Novel Benzamide-Type Cereblon Binders for the Design of PROTACs. J.Med.Chem., 66, 2023
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8OU5
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![BU of 8ou5 by Molmil](/molmil-images/mine/8ou5) | Cereblon isoform 4 in complex with novel Benzamide-Type Cereblon Binder 11b | 分子名称: | 4-azanyl-~{N}-[(3~{S})-2,6-bis(oxidanylidene)piperidin-3-yl]-2-(trifluoromethyl)benzamide, Cereblon isoform 4, ZINC ION | 著者 | Heim, C, Bischof, L, Hartmann, M.D. | 登録日 | 2023-04-21 | 公開日 | 2023-11-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Leveraging Ligand Affinity and Properties: Discovery of Novel Benzamide-Type Cereblon Binders for the Design of PROTACs. J.Med.Chem., 66, 2023
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8OU7
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![BU of 8ou7 by Molmil](/molmil-images/mine/8ou7) | Cereblon isoform 4 in complex with novel Benzamide-Type Cereblon Binder 11d | 分子名称: | 4-azanyl-~{N}-[(3~{S})-2,6-bis(oxidanylidene)piperidin-3-yl]-2-methoxy-benzamide, Cereblon isoform 4, ZINC ION | 著者 | Heim, C, Bischof, L, Hartmann, M.D. | 登録日 | 2023-04-22 | 公開日 | 2023-11-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Leveraging Ligand Affinity and Properties: Discovery of Novel Benzamide-Type Cereblon Binders for the Design of PROTACs. J.Med.Chem., 66, 2023
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8OU9
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![BU of 8ou9 by Molmil](/molmil-images/mine/8ou9) | Cereblon isoform 4 in complex with novel Benzamide-Type Cereblon Binder 11e | 分子名称: | 4-azanyl-~{N}-[(3~{S})-2,6-bis(oxidanylidene)piperidin-3-yl]-2-oxidanyl-benzamide, Cereblon isoform 4, ZINC ION | 著者 | Heim, C, Bischof, L, Hartmann, M.D. | 登録日 | 2023-04-22 | 公開日 | 2023-11-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Leveraging Ligand Affinity and Properties: Discovery of Novel Benzamide-Type Cereblon Binders for the Design of PROTACs. J.Med.Chem., 66, 2023
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8OUA
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![BU of 8oua by Molmil](/molmil-images/mine/8oua) | Cereblon isoform 4 in complex with novel Benzamide-Type Cereblon Binder 11f | 分子名称: | 4-azanyl-~{N}-[(3~{S})-2,6-bis(oxidanylidene)piperidin-3-yl]-2,5-bis(fluoranyl)-3-methoxy-benzamide, Cereblon isoform 4, PHOSPHATE ION, ... | 著者 | Heim, C, Bischof, L, Hartmann, M.D. | 登録日 | 2023-04-22 | 公開日 | 2023-11-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Leveraging Ligand Affinity and Properties: Discovery of Novel Benzamide-Type Cereblon Binders for the Design of PROTACs. J.Med.Chem., 66, 2023
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5XEQ
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![BU of 5xeq by Molmil](/molmil-images/mine/5xeq) | Crystal Structure of human MDGA1 and human neuroligin-2 complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MAM domain-containing glycosylphosphatidylinositol anchor protein 1, ... | 著者 | Kim, H.M, Kim, J.A, Kim, D. | 登録日 | 2017-04-05 | 公開日 | 2017-07-12 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.136 Å) | 主引用文献 | Structural Insights into Modulation of Neurexin-Neuroligin Trans-synaptic Adhesion by MDGA1/Neuroligin-2 Complex Neuron, 94, 2017
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8CLO
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![BU of 8clo by Molmil](/molmil-images/mine/8clo) | Zearalenone lactonase from Streptomyces coelicoflavus | 分子名称: | 1,2-ETHANEDIOL, Hydrolase | 著者 | Puehringer, D, Grishkovskaya, I, Mlynek, G, Kostan, J. | 登録日 | 2023-02-17 | 公開日 | 2024-02-21 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Bacterial Lactonases ZenA with Noncanonical Structural Features Hydrolyze the Mycotoxin Zearalenone. Acs Catalysis, 14, 2024
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6XDS
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6YJ6
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![BU of 6yj6 by Molmil](/molmil-images/mine/6yj6) | Structure of the TFIIIC subcomplex tauA | 分子名称: | Transcription factor tau 131 kDa subunit, Transcription factor tau 55 kDa subunit, Transcription factor tau 95 kDa subunit,Transcription factor tau 95 kDa subunit | 著者 | Vorlaender, M.K, Muller, C.W. | 登録日 | 2020-04-02 | 公開日 | 2020-09-16 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structure of the TFIIIC subcomplex tau A provides insights into RNA polymerase III pre-initiation complex formation. Nat Commun, 11, 2020
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6ZN3
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2PY2
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![BU of 2py2 by Molmil](/molmil-images/mine/2py2) | Structure of Herring Type II Antifreeze Protein | 分子名称: | Antifreeze protein type II, CALCIUM ION | 著者 | Liu, Y, Li, Z, Lin, Q, Seetharaman, J, Sivaraman, J, Hew, C.-L. | 登録日 | 2007-05-15 | 公開日 | 2007-06-26 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structure and Evolutionary Origin of Ca-Dependent Herring Type II Antifreeze Protein. PLoS ONE, 2, 2007
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2XZS
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![BU of 2xzs by Molmil](/molmil-images/mine/2xzs) | Death associated protein kinase 1 residues 1-312 | 分子名称: | DEATH ASSOCIATED KINASE 1, MAGNESIUM ION | 著者 | Yumerefendi, H, Mas, P.J, Dordevic, N, McCarthy, A.A, Hart, D.J. | 登録日 | 2010-11-29 | 公開日 | 2011-12-07 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Death-Associated Protein Kinase Activity is Regulated by Coupled Calcium/Calmodulin Binding to Two Distinct Sites. Structure, 24, 2016
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