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1MY3
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BU of 1my3 by Molmil
crystal structure of glutamate receptor ligand-binding core in complex with bromo-willardiine in the Zn crystal form
分子名称: 2-AMINO-3-(5-BROMO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, GLUTAMATE RECEPTOR 2, ZINC ION
著者Jin, R, Gouaux, E.
登録日2002-10-03
公開日2003-06-10
最終更新日2017-08-23
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Probing the Function, Conformational Plasticity, and Dimer-Dimer Contacts of the GluR2 Ligand-Binding Core: Studies of 5-Substituted Willardiines and GluR2 S1S2 in the Crystal
Biochemistry, 42, 2003
3IJ4
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BU of 3ij4 by Molmil
Cesium sites in the crystal structure of a functional acid sensing ion channel in the desensitized state
分子名称: Amiloride-sensitive cation channel 2, neuronal, CESIUM ION, ...
著者Gonzales, E.B, Gouaux, E.
登録日2009-08-03
公開日2009-11-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Pore architecture and ion sites in acid-sensing ion channels and P2X receptors.
Nature, 460, 2009
3USM
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BU of 3usm by Molmil
Crystal Structure of LeuT bound to L-selenomethionine in space group C2 from lipid bicelles (collected at 1.2 A)
分子名称: IODIDE ION, PHOSPHOCHOLINE, SELENOMETHIONINE, ...
著者Wang, H, Elferich, J, Gouaux, E.
登録日2011-11-23
公開日2012-01-11
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (3.008 Å)
主引用文献Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context.
Nat.Struct.Mol.Biol., 19, 2012
3USP
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BU of 3usp by Molmil
Crystal structure of LeuT in heptyl-beta-D-Selenoglucoside
分子名称: CHLORIDE ION, LEUCINE, SODIUM ION, ...
著者Wang, H, Elferich, J, Gouaux, E.
登録日2011-11-23
公開日2012-01-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context.
Nat.Struct.Mol.Biol., 19, 2012
3GIA
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BU of 3gia by Molmil
Crystal Structure of ApcT Transporter
分子名称: BICINE, DECANE, Uncharacterized protein MJ0609
著者Shaffer, P.L, Goehring, A.S, Shankaranarayanan, A, Gouaux, E, New York Consortium on Membrane Protein Structure (NYCOMPS)
登録日2009-03-05
公開日2009-08-18
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Structure and mechanism of a na+-independent amino Acid transporter.
Science, 325, 2009
3USL
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BU of 3usl by Molmil
Crystal Structure of LeuT bound to L-selenomethionine in space group C2 from lipid bicelles
分子名称: ACETATE ION, IODIDE ION, PHOSPHOCHOLINE, ...
著者Wang, H, Elferich, J, Gouaux, E.
登録日2011-11-23
公開日2012-01-11
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context.
Nat.Struct.Mol.Biol., 19, 2012
3I5D
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BU of 3i5d by Molmil
Crystal structure of the ATP-gated P2X4 ion channel in the closed, apo state at 3.5 Angstroms (R3)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, P2X purinoceptor
著者Kawate, T, Michel, J.C, Gouaux, E.
登録日2009-07-05
公開日2009-08-04
最終更新日2021-10-13
実験手法X-RAY DIFFRACTION (3.46 Å)
主引用文献Crystal structure of the ATP-gated P2X(4) ion channel in the closed state.
Nature, 460, 2009
1MQH
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BU of 1mqh by Molmil
Crystal Structure of the GluR2 Ligand Binding Core (S1S2J) in Complex with Bromo-Willardiine at 1.8 Angstroms Resolution
分子名称: 2-AMINO-3-(5-BROMO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, glutamate receptor 2
著者Jin, R, Banke, T.G, Mayer, M.L, Traynelis, S.F, Gouaux, E.
登録日2002-09-16
公開日2003-08-05
最終更新日2017-08-02
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis for partial agonist action at ionotropic glutamate receptors
Nat.Neurosci., 6, 2003
3USJ
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BU of 3usj by Molmil
Crystal structure of LeuT bound to L-leucine in space group P21 from lipid bicelles
分子名称: LEUCINE, SODIUM ION, Transporter
著者Wang, H, Elferich, J, Gouaux, E.
登録日2011-11-23
公開日2012-01-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context.
Nat.Struct.Mol.Biol., 19, 2012
3USK
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BU of 3usk by Molmil
Crystal structure of LeuT bound to L-leucine in space group P21 from lipid bicelles
分子名称: LEUCINE, SODIUM ION, Transporter
著者Wang, H, Elferich, J, Gouaux, E.
登録日2011-11-23
公開日2012-01-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (4.5 Å)
主引用文献Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context.
Nat.Struct.Mol.Biol., 19, 2012
3USO
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BU of 3uso by Molmil
Crystal structure of LeuT bound to L-selenomethionine in space group P21212 from lipid bicelles
分子名称: SELENOMETHIONINE, SODIUM ION, Transporter
著者Wang, H, Elferich, J, Gouaux, E.
登録日2011-11-23
公開日2012-01-11
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (4.5 Å)
主引用文献Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context.
Nat.Struct.Mol.Biol., 19, 2012
1MQG
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BU of 1mqg by Molmil
Crystal Structure of the GluR2 Ligand Binding Core (S1S2J) in Complex with Iodo-Willardiine at 2.15 Angstroms Resolution
分子名称: 2-AMINO-3-(5-IODO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, GLYCEROL, SULFATE ION, ...
著者Jin, R, Banke, T.G, Mayer, M.L, Traynelis, S.F, Gouaux, E.
登録日2002-09-16
公開日2003-08-05
最終更新日2017-05-10
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural basis for partial agonist action at ionotropic glutamate receptors
Nat.Neurosci., 6, 2003
3H9V
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BU of 3h9v by Molmil
Crystal structure of the ATP-gated P2X4 ion channel in the closed, apo state at 3.1 Angstroms
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GADOLINIUM ATOM, P2X purinoceptor
著者Kawate, T, Michel, J.C, Gouaux, E.
登録日2009-04-30
公開日2009-07-28
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal structure of the ATP-gated P2X(4) ion channel in the closed state.
Nature, 460, 2009
3USI
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BU of 3usi by Molmil
Crystal structure of LeuT bound to L-leucine in space group P2 from lipid bicelles
分子名称: LEUCINE, SODIUM ION, Transporter
著者Wang, H, Elferich, J, Gouaux, E.
登録日2011-11-23
公開日2012-01-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.106 Å)
主引用文献Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context.
Nat.Struct.Mol.Biol., 19, 2012
3H5V
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BU of 3h5v by Molmil
Crystal structure of the GluR2-ATD
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2
著者Jin, R, Singh, S.K, Gu, S, Furukawa, H, Sobolevsky, A, Zhou, J, Jin, Y, Gouaux, E.
登録日2009-04-22
公開日2009-06-09
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Crystal structure and association behaviour of the GluR2 amino-terminal domain.
Embo J., 28, 2009
1MQJ
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BU of 1mqj by Molmil
Crystal structure of the GluR2 ligand binding core (S1S2J) in complex with willardiine at 1.65 angstroms resolution
分子名称: 2-AMINO-3-(2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, ZINC ION, glutamate receptor 2
著者Jin, R, Banke, T.G, Mayer, M.L, Traynelis, S.F, Gouaux, E.
登録日2002-09-16
公開日2003-08-05
最終更新日2017-08-02
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural basis for partial agonist action at ionotropic glutamate receptors
Nat.Neurosci., 6, 2003
1MXW
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BU of 1mxw by Molmil
crystal titration experiments (AMPA co-crystals soaked in 1 mM BrW)
分子名称: GLUTAMATE RECEPTOR 2, ZINC ION
著者Jin, R, Gouaux, E.
登録日2002-10-03
公開日2003-06-10
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Probing the function, conformational plasticity, and dimer-dimer contacts of the GluR2 ligand-binding core: studies of 5-substituted willardiines and GluR2 S1S2 in the crystal.
Biochemistry, 42, 2003
1MXY
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BU of 1mxy by Molmil
crystal titration experiments (AMPA co-crystals soaked in 10 uM BrW)
分子名称: GLUTAMATE RECEPTOR 2, ZINC ION
著者Jin, R, Gouaux, E.
登録日2002-10-03
公開日2003-06-10
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Probing the function, conformational plasticity, and dimer-dimer contacts of the GluR2 ligand-binding core: studies of 5-substituted willardiines and GluR2 S1S2 in the crystal.
Biochemistry, 42, 2003
3GI8
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BU of 3gi8 by Molmil
Crystal Structure of ApcT K158A Transporter Bound to 7F11 Monoclonal Fab Fragment
分子名称: 7F11 Anti-ApcT Monoclonal Fab Heavy Chain, 7F11 Anti-ApcT Monoclonal Fab Light Chain, Uncharacterized protein MJ0609
著者Shaffer, P.L, Goehring, A.S, Shankaranarayanan, A, Gouaux, E, New York Consortium on Membrane Protein Structure (NYCOMPS)
登録日2009-03-05
公開日2009-08-18
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Structure and mechanism of a na+-independent amino Acid transporter.
Science, 325, 2009
1MXZ
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BU of 1mxz by Molmil
crystal titration experiments (AMPA co-crystals soaked in 1 uM BrW)
分子名称: GLUTAMATE RECEPTOR 2, ZINC ION
著者Jin, R, Gouaux, E.
登録日2002-10-03
公開日2003-06-10
最終更新日2017-08-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Probing the function, conformational plasticity, and dimer-dimer contacts of the GluR2 ligand-binding core: studies of 5-substituted willardiines and GluR2 S1S2 in the crystal.
Biochemistry, 42, 2003
1MY4
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BU of 1my4 by Molmil
crystal structure of glutamate receptor ligand-binding core in complex with iodo-willardiine in the Zn crystal form
分子名称: 2-AMINO-3-(5-IODO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, GLUTAMATE RECEPTOR 2, ZINC ION
著者Jin, R, Gouaux, E.
登録日2002-10-03
公開日2003-06-10
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Probing the Function, Conformational Plasticity, and Dimer-Dimer Contacts of the GluR2 Ligand-Binding Core: Studies of 5-Substituted Willardiines and GluR2 S1S2 in the Crystal
Biochemistry, 42, 2003
3TT3
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BU of 3tt3 by Molmil
Crystal Structure of LeuT in the inward-open conformation in complex with Fab
分子名称: Leucine transporter LeuT, mouse monoclonal 1gG1 Fab fragment, heavy chain, ...
著者Krishnamurthy, H, Gouaux, E.
登録日2011-09-13
公開日2012-01-04
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.22 Å)
主引用文献X-ray structures of LeuT in substrate-free outward-open and apo inward-open states.
Nature, 481, 2012
3TU0
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BU of 3tu0 by Molmil
Crystal structure of T355V, S354A, K288A LeuT mutant in complex with alanine and sodium
分子名称: ALANINE, Leucine transporter LeuT, SODIUM ION
著者Krishnamurthy, H, Gouaux, E.
登録日2011-09-15
公開日2012-01-04
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.994 Å)
主引用文献X-ray structures of LeuT in substrate-free outward-open and apo inward-open states.
Nature, 481, 2012
3H5W
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BU of 3h5w by Molmil
Crystal structure of the GluR2-ATD in space group P212121 without solvent
分子名称: Glutamate receptor 2
著者Jin, R, Singh, S.K, Gu, S, Furukawa, H, Sobolevsky, A, Zhou, J, Jin, Y, Gouaux, E.
登録日2009-04-22
公開日2009-06-09
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.686 Å)
主引用文献Crystal structure and association behaviour of the GluR2 amino-terminal domain.
Embo J., 28, 2009
3JAF
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BU of 3jaf by Molmil
Structure of alpha-1 glycine receptor by single particle electron cryo-microscopy, glycine/ivermectin-bound state
分子名称: (2aE,4E,5'S,6S,6'R,7S,8E,11R,13R,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17 -oxo-3',4',5',6,6',10,11,14,15,17,17a,20,20a,20b-tetradecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacy clooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-3-O-methyl-alpha-L-arabino-hexopyranoside, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycine receptor subunit alphaZ1
著者Du, J, Lu, W, Wu, S.P, Cheng, Y.F, Gouaux, E.
登録日2015-06-08
公開日2015-09-09
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Glycine receptor mechanism elucidated by electron cryo-microscopy.
Nature, 526, 2015

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